BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0042.p (449 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1552 [O] COG0265 Trypsin-like serine proteases, typically per... 579 e-165 PA0766 [O] COG0265 Trypsin-like serine proteases, typically peri... 399 e-111 RSc1058 [O] COG0265 Trypsin-like serine proteases, typically per... 394 e-109 NMB0532 [O] COG0265 Trypsin-like serine proteases, typically per... 374 e-103 NMA0710 [O] COG0265 Trypsin-like serine proteases, typically per... 369 e-102 >RSp1552 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Rso Ralstonia solanacearum Length = 490 Score = 579 bits (1492), Expect = e-165, Method: Compositional matrix adjust. Identities = 301/437 (68%), Positives = 357/437 (81%), Gaps = 3/437 (0%) Query: 14 LATPTDFSGIVERAGPAVVNISVTGKAKRVS-DDASDDVDPNDPFSEFFKRFGPQFQQPP 72 +A P DFS IVER GPAVVNIS T +A+R S V P+DPF+EFF+RF PQ Q Sbjct: 54 VAVPMDFSAIVERYGPAVVNISTTARAQRTSIQGLPPGVSPDDPFAEFFRRFMPQAPQQ- 112 Query: 73 RTPQIMRGLGSGFIISPDGLILTNAHVVDGAQEVTVKLTDRREFKAKVLGADKQSDIAVI 132 + Q+++GLGSGFI+SPDGLILTNAHVVDGAQEV+VKLTDRREFKAKVLG DKQSD+AV+ Sbjct: 113 QGDQVVKGLGSGFIVSPDGLILTNAHVVDGAQEVSVKLTDRREFKAKVLGVDKQSDVAVL 172 Query: 133 RIAAKDLPTVQIGNPALMKVGEPVLAIGSPYGFDNTATAGIVSAKSRALPDDNYVPFIQT 192 RIAA +LPTVQIG+PA KVGEPVLAIGSPYGF+NT TAGIVSAKSR+LPDD YVPFIQT Sbjct: 173 RIAASNLPTVQIGSPAGTKVGEPVLAIGSPYGFENTVTAGIVSAKSRSLPDDTYVPFIQT 232 Query: 193 DVAVNPGNSGGPLFNLKGQVVGINSQIYSQTGGYQGLSFSIPIDVAMKVEQQLVQHGKVT 252 DVAVNPGNSGGPLFN +G+V+GINSQIYSQTGGYQGLSF++PIDVAMKVEQQLV GKVT Sbjct: 233 DVAVNPGNSGGPLFNQRGEVIGINSQIYSQTGGYQGLSFAVPIDVAMKVEQQLVATGKVT 292 Query: 253 RGRLGVSVQEINQALAESFGLKKSEGALVSSVEKGSPAEKAGVQAGDVILRFNGQAIDHS 312 RGRLG+SVQE++Q+LA+SF L K EGALV++VEK PA KAG+Q GDVIL+ I HS Sbjct: 293 RGRLGISVQEVDQSLADSFNLPKPEGALVNAVEKDGPAAKAGLQPGDVILQIGDVHIGHS 352 Query: 313 VDLPTLVADTAPGTTQKIEVMRNGALKSLNITVGELKPTKEAAASRNEP-QGRLGLAVRP 371 DLP VA+ PG+T ++++R+G +L++TVGE K K AA + P +GRLGLAVRP Sbjct: 353 GDLPEQVAEIKPGSTVPLQIIRHGKPTALSVTVGEAKDAKVAANTSAAPDKGRLGLAVRP 412 Query: 372 LDKSEQQQIGVHGGLLVEDVNGPAAVAGIQSGDVILSLNGNAVTSVEQLRSLVSKAGKSV 431 L E++Q G+ GGL+V D +GPAA AGIQ GDVILSLNG V+S ++LR+LV +AGK V Sbjct: 413 LQAEEKRQSGLPGGLVVMDSSGPAAKAGIQPGDVILSLNGTPVSSAQELRALVDRAGKHV 472 Query: 432 ALLVERGDDKIFVPVYL 448 ALLV+R D KIFVP+ L Sbjct: 473 ALLVQRDDAKIFVPLDL 489 >PA0766 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Pae Pseudomonas aeruginosa Length = 474 Score = 399 bits (1025), Expect = e-111, Method: Compositional matrix adjust. Identities = 226/445 (50%), Positives = 306/445 (68%), Gaps = 16/445 (3%) Query: 19 DFSGIVERAGPAVVNISVTGK----AKRVSDDASDDVDPNDP-FSEFFKRFGPQFQQPPR 73 DF+ +VE+A PAVVNIS K A + D++ P F +F +R PQ + PR Sbjct: 29 DFTPLVEQASPAVVNISTRQKLPDRAMARGQLSIPDLEGLPPMFRDFLERSIPQVPRNPR 88 Query: 74 TPQI-MRGLGSGFIISPDGLILTNAHVVDGAQEVTVKLTDRREFKAKVLGADKQSDIAVI 132 Q + LGSGFIIS DG ILTN HVV A E+ V+L+DR E KAK++GAD +SD+AV+ Sbjct: 89 GQQREAQSLGSGFIISNDGYILTNNHVVADADEILVRLSDRSEHKAKLIGADPRSDVAVL 148 Query: 133 RIAAKDLPTVQIGNPALMKVGEPVLAIGSPYGFDNTATAGIVSAKSRALPDDNYVPFIQT 192 +I AK+LPT+++G+ +KVGE VLAIGSP+GFD++ TAGIVSAK R+LP+++YVPFIQT Sbjct: 149 KIEAKNLPTLKLGDSNKLKVGEWVLAIGSPFGFDHSVTAGIVSAKGRSLPNESYVPFIQT 208 Query: 193 DVAVNPGNSGGPLFNLKGQVVGINSQIYSQTGGYQGLSFSIPIDVAMKVEQQLVQHGKVT 252 DVA+NPGNSGGPL NL+G+VVGINSQI++++GG+ GLSF+IPIDVA+ V QL + GKV+ Sbjct: 209 DVAINPGNSGGPLLNLQGEVVGINSQIFTRSGGFMGLSFAIPIDVALNVADQLKKAGKVS 268 Query: 253 RGRLGVSVQEINQALAESFGLKKSEGALVSSVEKGSPAEKAGVQAGDVILRFNGQAIDHS 312 RG LGV +QE+N+ LAESFGL K GALV+ + + PA K G+Q GDVIL NGQ+I+ S Sbjct: 269 RGWLGVVIQEVNKDLAESFGLDKPSGALVAQLVEDGPAAKGGLQVGDVILSLNGQSINES 328 Query: 313 VDLPTLVADTAPGTTQKIEVMRNGALKSLNITVGELKPTKEAAASRNEP-----QGRLGL 367 DLP LV + PG ++V+RNG KSL++ VG L E AS P RLG+ Sbjct: 329 ADLPHLVGNMKPGDKINLDVIRNGQRKSLSMAVGSLPDDDEEIASMGAPGAERSSNRLGV 388 Query: 368 AVRPLDKSEQQQIGVHGGLLVEDV-NGPAAVAGIQSGDVILSLNGNAVTSVEQLRSLVSK 426 V L +++ + + GG+++++V +GPAAV G++ GDVI L+ AVTS + V+K Sbjct: 389 TVADLTAEQRKSLDIQGGVVIKEVQDGPAAVIGLRPGDVITHLDNKAVTSTKVFAD-VAK 447 Query: 427 A---GKSVALLVERGDDKIFVPVYL 448 A +SV++ V R F+ L Sbjct: 448 ALPKNRSVSMRVLRQGRASFITFKL 472 >RSc1058 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Rso Ralstonia solanacearum Length = 505 Score = 394 bits (1013), Expect = e-109, Method: Compositional matrix adjust. Identities = 220/471 (46%), Positives = 311/471 (66%), Gaps = 46/471 (9%) Query: 4 PVVAAPSSPTLATPT----DFSGIVERAGPAVVNISVTGKAKRVSDDASDDVDPNDPFSE 59 P A ++ ++AT T DF+ +VE+ PAVVNI T K R+ ++ SDD +E Sbjct: 27 PAYAQNATGSVATGTYGLPDFADLVEKVSPAVVNIRTTEKV-RMQNNPSDD-----DMAE 80 Query: 60 FFKRFGPQFQQP-PRTP-----------------QIMRGLGSGFIISPDGLILTNAHVVD 101 FF+RF F P P TP + RG+GSGFI+S DG +LTNAHVV+ Sbjct: 81 FFRRF---FGVPMPGTPGQGQGQKRRNAPPQAEEEQSRGVGSGFIMSGDGYVLTNAHVVE 137 Query: 102 GAQEVTVKLTDRREFKAKVLGADKQSDIAVIRIAAKDLPTVQIGNPALMKVGEPVLAIGS 161 GA+ + V LTD+REFKAK++G+DK++D+A++++ A LP++++G+ ++VGE VLAIGS Sbjct: 138 GAETIYVTLTDKREFKAKLIGSDKRTDVALVKVEATGLPSLKLGDSDKVRVGEWVLAIGS 197 Query: 162 PYGFDNTATAGIVSAKSRALPDDNYVPFIQTDVAVNPGNSGGPLFNLKGQVVGINSQIYS 221 P+G DNT TAGIVSAK R D Y+PFIQ+DVAVNPGNSGGPL NL+G+V+GIN+QI+S Sbjct: 198 PFGLDNTVTAGIVSAKGRDTGD--YLPFIQSDVAVNPGNSGGPLINLRGEVIGINNQIFS 255 Query: 222 QTGGYQGLSFSIPIDVAMKVEQQLVQHGKVTRGRLGVSVQEINQALAESFGLKKSEGALV 281 Q+GGY G+SF+IPID AM+V +QL G+VTRGR+GV++ + + AES GL ++ GA V Sbjct: 256 QSGGYMGISFAIPIDEAMRVAEQLKTQGRVTRGRIGVAIDNVPKDAAESLGLGRARGAYV 315 Query: 282 SSVEKGSPAEKAGVQAGDVILRFNGQAIDHSVDLPTLVADTAPGTTQKIEVMRNGALKSL 341 +VE G PA+KAG++AGD++L+FNG+ ++ + DL V ++ PGT ++V R GA + L Sbjct: 316 GNVESGGPADKAGIEAGDIVLKFNGRDVEKAGDLQRQVGESKPGTRATVQVWRKGATRDL 375 Query: 342 NITVGELKPTKEAA-------ASRNEP----QGRLGLAVRPLDKSEQQQIGVHGGLLVED 390 +TV EL+P + A + +P Q LGL V L + Q++ G+ V+ Sbjct: 376 TVTVAELQPDTKVAQRGKGGQSDNGQPGAGKQNALGLVVADLSEGAQREFKTKAGVEVQV 435 Query: 391 VNGPAAVAGIQSGDVILSLNGNAVTSVEQLRSLVSKAGKS--VALLVERGD 439 +GPAA AGI+ GDVIL + VTS +Q +V + KS VA+ V RGD Sbjct: 436 ADGPAARAGIRPGDVILRVGDTDVTSAKQFNDVVGRLDKSRMVAVFVRRGD 486 >NMB0532 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Nme Neisseria meningitidis MC58 Length = 499 Score = 374 bits (961), Expect = e-103, Method: Compositional matrix adjust. Identities = 213/443 (48%), Positives = 288/443 (65%), Gaps = 13/443 (2%) Query: 19 DFSGIVERAGPAVVNISVTG--KAKRVSDDASDDVDP---NDPFSEFFKRFGPQFQQPPR 73 DF+ +V+ GPAVVNI + + S +A +D DP NDPF EFFKR P + P+ Sbjct: 56 DFAQLVQSEGPAVVNIQAAPAPRTQNGSGNAENDSDPIADNDPFYEFFKRLVPNMPEIPQ 115 Query: 74 TPQIMRGL--GSGFIISPDGLILTNAHVVDGAQEVTVKLTDRREFKAKVLGADKQSDIAV 131 GL GSGFIIS DG ILTN HVV G + V L D+RE+ AK++G+D QSD+A+ Sbjct: 116 EEADDGGLNFGSGFIISKDGYILTNTHVVTGMGSIKVLLNDKREYTAKLIGSDVQSDVAL 175 Query: 132 IRI-AAKDLPTVQIGNPALMKVGEPVLAIGSPYGFDNTATAGIVSAKSRALPDDNYVPFI 190 ++I A ++LP V+IGNP +K GE V AIG+P+GFDN+ TAGIVSAK R+LP+++Y PFI Sbjct: 176 LKIDATEELPVVKIGNPKDLKPGEWVAAIGAPFGFDNSVTAGIVSAKGRSLPNESYTPFI 235 Query: 191 QTDVAVNPGNSGGPLFNLKGQVVGINSQIYSQTGGYQGLSFSIPIDVAMKVEQQLVQHGK 250 QTDVA+NPGNSGGPLFNLKGQVVGINSQIYS++GG+ G+SF+IPIDVAM V +QL GK Sbjct: 236 QTDVAINPGNSGGPLFNLKGQVVGINSQIYSRSGGFMGISFAIPIDVAMNVAEQLKNTGK 295 Query: 251 VTRGRLGVSVQEINQALAESFGLKKSEGALVSSVEKGSPAEKAGVQAGDVILRFNGQAID 310 V RG+LGV +QE++ LA+SFGL K+ GAL++ + GSPAE+AG+QAGD++L +G I Sbjct: 296 VQRGQLGVIIQEVSYGLAQSFGLDKAGGALIAKILPGSPAERAGLQAGDIVLSLDGGEIR 355 Query: 311 HSVDLPTLVADTAPGTTQKIEVMRNGALKSLNITVGELKPTKEAAASRNE----PQGRLG 366 S DLP +V PG + V R G ++ + +G A++ +E Q Sbjct: 356 SSGDLPVMVGAITPGKEVSLGVWRKGEEITIKVKLGNAAEHIGASSKTDEAPYTEQQSGT 415 Query: 367 LAVRPLDKSEQQQIGVHGG-LLVEDVNGPAAVAGIQSGDVILSLNGNAVTSVEQLRSLVS 425 +V + Q GG L+V V+ A AG++ GD IL++ V R + Sbjct: 416 FSVESAGITLQTHTDSSGGHLVVVRVSDAAERAGLRRGDEILAVGQVPVNDEAGFRKAMD 475 Query: 426 KAGKSVALLVERGDDKIFVPVYL 448 KAGK+V LL+ R + +F+ + L Sbjct: 476 KAGKNVPLLIMRRGNTLFIALNL 498 >NMA0710 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain NmA Neisseria meningitidis Z2491 Length = 499 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 211/443 (47%), Positives = 286/443 (64%), Gaps = 13/443 (2%) Query: 19 DFSGIVERAGPAVVNISVTG--KAKRVSDDASDDVDP---NDPFSEFFKRFGPQFQQPPR 73 DF +V+ GPAVVNI + + S +A D DP +DPF EFFKR P + P+ Sbjct: 56 DFVQLVQSEGPAVVNIQAAPAPRTQNGSSNAETDSDPLADSDPFYEFFKRLVPNMPEIPQ 115 Query: 74 TPQIMRGL--GSGFIISPDGLILTNAHVVDGAQEVTVKLTDRREFKAKVLGADKQSDIAV 131 GL GSGFIIS DG ILTN HVV G + V L D+RE+ AK++G+D QSD+A+ Sbjct: 116 EEADDGGLNFGSGFIISKDGYILTNTHVVTGMGSIKVLLNDKREYTAKLIGSDVQSDVAL 175 Query: 132 IRI-AAKDLPTVQIGNPALMKVGEPVLAIGSPYGFDNTATAGIVSAKSRALPDDNYVPFI 190 ++I A ++LP V+IGNP +K GE V AIG+P+GFDN+ TAGIVSAK R+LP+++Y PFI Sbjct: 176 LKIDATEELPVVKIGNPKDLKPGEWVAAIGAPFGFDNSVTAGIVSAKGRSLPNESYTPFI 235 Query: 191 QTDVAVNPGNSGGPLFNLKGQVVGINSQIYSQTGGYQGLSFSIPIDVAMKVEQQLVQHGK 250 QTDVA+NPGNSGGPLFNLKGQVVGINSQIYS++GG+ G+SF+IPIDVAM V +QL GK Sbjct: 236 QTDVAINPGNSGGPLFNLKGQVVGINSQIYSRSGGFMGISFAIPIDVAMNVAEQLKNTGK 295 Query: 251 VTRGRLGVSVQEINQALAESFGLKKSEGALVSSVEKGSPAEKAGVQAGDVILRFNGQAID 310 V RG+LGV +QE++ LA+SFGL K+ GAL++ + GSPAE+AG++AGD++L +G I Sbjct: 296 VQRGQLGVIIQEVSYGLAQSFGLDKAGGALIAKILPGSPAERAGLRAGDIVLSLDGGEIR 355 Query: 311 HSVDLPTLVADTAPGTTQKIEVMRNGALKSLNITVGELKPTKEAAASRNEP----QGRLG 366 S DLP +V PG + V R G ++ + +G A++ +E Q Sbjct: 356 SSGDLPVMVGAITPGKEVSLGVWRKGEEITIKVKLGNAAEHIGASSKTDEAPYTEQQSGT 415 Query: 367 LAVRPLDKSEQQQIGVHGG-LLVEDVNGPAAVAGIQSGDVILSLNGNAVTSVEQLRSLVS 425 +V + Q GG L+V V+ A AG++ GD IL++ V R + Sbjct: 416 FSVESAGITLQTHTDSSGGHLVVVRVSDAAERAGLRRGDEILAVGQVPVNDEAGFRKAMD 475 Query: 426 KAGKSVALLVERGDDKIFVPVYL 448 KAGK+V LL+ R + +F+ + L Sbjct: 476 KAGKNVPLLIMRRGNTLFIALNL 498