BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0060.p (1149 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralsto... 1548 0.0 NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisse... 1170 0.0 NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisse... 1158 0.0 PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudom... 1062 0.0 STM0231 [L] COG0587 DNA polymerase III, alpha subunit Sty Salmon... 1021 0.0 >RSc2205 [L] COG0587 DNA polymerase III, alpha subunit Rso Ralstonia solanacearum Length = 1173 Score = 1548 bits (4009), Expect = 0.0, Method: Compositional matrix adjust. Identities = 785/1178 (66%), Positives = 928/1178 (78%), Gaps = 35/1178 (2%) Query: 1 MTTPQFVHLRLHSEYSIVDGLVRIDDVVKAAAKDGQAALAITDLANLFGMVKFYKGARGK 60 M +P+FVHLRLHSEYS+VDG VR+D+ VKAAA DG ALA+TDLAN FG+V+FYK ARGK Sbjct: 1 MNSPRFVHLRLHSEYSVVDGNVRLDEAVKAAAADGMGALALTDLANAFGLVRFYKEARGK 60 Query: 61 GVKPIAGCDVWISNDDDRDKPTRLLLLVKDHHGYLQLCDLLSRAWLTNLHRGRAELRPEW 120 GVKPI G DVWI+N D+RDKP+RLLLLV++ GYL LC LL+RAWL+N HRGRAE+ PEW Sbjct: 61 GVKPIVGADVWITNHDERDKPSRLLLLVRNKQGYLNLCMLLARAWLSNQHRGRAEVAPEW 120 Query: 121 LEQLRHDEG--GNGLIALSGAHFGDVGIAIENGNVAAAERAAQRWSEVFPGAFYVEIQRA 178 + +E GL+ALSGA GD+G+A+ NGN A A + A +WS+VFP +FY+E+QRA Sbjct: 121 FGEPGVEEAPMATGLLALSGAMGGDIGMALANGNEALARKLATQWSQVFPASFYIELQRA 180 Query: 179 NQPNMEVQVRQSVALAARLALPVVATHPIQFLSQDEFVAHEARTCIAEGEILANARRVRR 238 E V+Q+V LAA + LPVVATHP+QF++ D+F AHEAR CIAEG++LAN RR RR Sbjct: 181 GNAGTEAYVQQAVKLAASMQLPVVATHPVQFMTPDDFTAHEARVCIAEGDLLANPRRTRR 240 Query: 239 FNEQQNFKTQAEMAALFADLPGAVQNTIEIAKRCNLMLTLGKPQLPNFPTPDGMTIDDFL 298 F Q FKTQ EM ALFAD+P A+ NT +IA+RCNL L LGKP+LP FPTPDGM++DD+L Sbjct: 241 FTTDQYFKTQDEMCALFADIPSALANTAQIAQRCNLTLELGKPKLPLFPTPDGMSLDDYL 300 Query: 299 VAETKIGLEARLKHLYPDEARREKERPRYEARLKFENDTIIKMKFPGYFLIVADFIQWAK 358 V K GLE R+ L+PDEA RE +RP Y ARL+FE TIIKM FPGYFLIVADFI WAK Sbjct: 301 VHLAKDGLEKRMAVLFPDEAVREAKRPEYYARLEFETGTIIKMGFPGYFLIVADFINWAK 360 Query: 359 NNGVPVGPGRGSGAGSLVAYALSITDLDPLEYNLLFERFLNPERVSMPDFDIDFCQEGRD 418 NNGVPVGPGRGSGAGSLVAYAL ITDLDPL+YNLLFERFLNPERVSMPDFDIDFCQ GRD Sbjct: 361 NNGVPVGPGRGSGAGSLVAYALGITDLDPLKYNLLFERFLNPERVSMPDFDIDFCQHGRD 420 Query: 419 RVIQYVKDRYGKEAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVT 478 RVI YVK++YGK+AVSQIATFGTMAAK AVRDVGRVLDLGYNF DG++KLIPFKPGKLVT Sbjct: 421 RVIHYVKEKYGKDAVSQIATFGTMAAKAAVRDVGRVLDLGYNFVDGVAKLIPFKPGKLVT 480 Query: 479 LADAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMX---VLIAPGKLTDFCPLYT 535 + +A +EEPLL ER NEEEVKQL+ LAQ+VEG+ RN+GM VLIAPGKLTDFCPLYT Sbjct: 481 IEEAKKEEPLLAEREANEEEVKQLLELAQRVEGMTRNVGMHAGGVLIAPGKLTDFCPLYT 540 Query: 536 QGG-DAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIKQLDPAMADFDLARLPL 594 QGG DAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILD A RYI+ LDP+ AD++ + +PL Sbjct: 541 QGGEDAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDWAERYIRTLDPSRADWNCSHIPL 600 Query: 595 TDRASYDLLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFCK 654 TD+A++D+L A TVAVFQLESRGMQGMLKDA+PDRFEDIIALVALYRPGPMDLIP FC Sbjct: 601 TDKAAFDILKTANTVAVFQLESRGMQGMLKDAKPDRFEDIIALVALYRPGPMDLIPSFCA 660 Query: 655 RKHG-EKFDYPDPRTEGILSETYGIMVYQEQVMQMAQVVGGYSLGGADLLRRAMGKKKAE 713 RKHG EK +YPDPR E +L ETYGIMVYQEQVMQMAQ+VGGYSLGGADLLRRAMGKKKAE Sbjct: 661 RKHGREKVEYPDPRVEPVLKETYGIMVYQEQVMQMAQIVGGYSLGGADLLRRAMGKKKAE 720 Query: 714 EMAEHRNIFREGAAKDGLSQEKADEIFDLMEKFAGYGFNKSHAAAYALLSYHTAYLKAHH 773 EMAEHR +FR GAAKDGLS EKADEIFDLMEKFAGYGFNKSHAAAYALL+Y+TA+LKAHH Sbjct: 721 EMAEHRELFRGGAAKDGLSTEKADEIFDLMEKFAGYGFNKSHAAAYALLAYYTAWLKAHH 780 Query: 774 PAAFMAANLSLAMDDTEKIKILVEDSLDVCGLSLLPPDINLSDYRFIPVGEPGKKAVHIR 833 PA FMAAN+SLAMDDT+K+KIL +D+ GL++LPPDIN S YRF P A IR Sbjct: 781 PAEFMAANMSLAMDDTDKVKILYDDARGKNGLAVLPPDINASQYRFTPT-----DAKTIR 835 Query: 834 YGLGAVKGSGQSAIEAIIAARQDGPFKDLFDFAKRVDKKQINRRTVDSLIRAGAFDCFGV 893 YGLG VKGSGQ AIE I+ AR+DGPFKDLFDF +RVD++Q+NRRT+++L+RAGAFD Sbjct: 836 YGLGGVKGSGQGAIEDILRAREDGPFKDLFDFCERVDRRQVNRRTIEALVRAGAFDSLNA 895 Query: 894 DRAILQATVGLAWENAEQMEASANQVSLF---GGDDSDLETPLEYVQVRPWSDKQRLTEE 950 +RA L ++GLA E AEQ A+ANQVSLF G DD++ P E + PWS K++L EE Sbjct: 896 NRAQLLVSIGLAMEAAEQKAAAANQVSLFDLMGSDDAEQHRP-ELLDEAPWSTKRKLQEE 954 Query: 951 KTALGFYLSGHLFDAYEKEVRQFVRTKISSL-------------EPSRDPR--SLAGIIT 995 K ALGFYLSGHLFD EVR+F RT ++ L SRD R ++AG+I Sbjct: 955 KQALGFYLSGHLFDECRDEVRRFARTTLADLAREVNGNGNNGGGYGSRDARNKTVAGVIV 1014 Query: 996 GIRVQMTQRGKLLIVSLDDGSGT--VDVTVYGELAEPNKAFFKEDELLIVQGKVSEDRFN 1053 G+R QMTQRGK+++V LDDGS + +VTV+ EL + N+A FKEDE+LIVQG D F Sbjct: 1015 GLRTQMTQRGKMIVVMLDDGSQSEATEVTVFNELFDANRALFKEDEVLIVQGNARHDTFT 1074 Query: 1054 GGLRISAEKVMDIGAARIQYGQRVVVSLNKSVDPVHLRDTLSSYRQPQ--GLPFVMKYVQ 1111 GG+R++AE V+D+ AR +Y + ++ + LR+ L+ Y Q G+ + Y Sbjct: 1075 GGVRMTAEAVLDLTQARARYADAIGLTFRDNASAARLRELLTPYLAAQVPGVRVRISYAA 1134 Query: 1112 SGVGCEVMLGDAWRVVPSDGLQVSLRESFGQEAVVVEY 1149 +G CE +LG+ W+V PSD + S R + E V + Y Sbjct: 1135 NGARCEAVLGEQWQVTPSDEVLASFRSALSTENVYMIY 1172 >NMB1827 [L] COG0587 DNA polymerase III, alpha subunit Nme Neisseria meningitidis MC58 Length = 1144 Score = 1170 bits (3026), Expect = 0.0, Method: Compositional matrix adjust. Identities = 608/1161 (52%), Positives = 793/1161 (68%), Gaps = 29/1161 (2%) Query: 1 MTTPQFVHLRLHSEYSIVDGLVRIDDVVKAAAKDGQAALAITDLANLFGMVKFYKGARGK 60 MT P ++ LRLH+E+SI DG+VRI ++ A + G AL I+DL N FG+VKFYK R Sbjct: 1 MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSA 60 Query: 61 GVKPIAGCDVWISNDDDRDKPTRLLLLVKDHHGYLQLCDLLSRAWL---TNLHRGRAELR 117 G+KPI DV I N D DKP R +L++++ GYL+L +LL+ A++ N+H AEL Sbjct: 61 GIKPIGAADVRIGNPDAPDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHH--AELN 118 Query: 118 PEWLEQLRHDEGGNGLIALSGAHFGDVGIAIENGNVAAAERAAQRWSEVFPGAFYVEIQR 177 PEWLE + +GLI LSGAH+G+VG+ + NGN AA AA +++ FP AFY+E+QR Sbjct: 119 PEWLE----NGDNSGLICLSGAHYGEVGVNLLNGNEDAARTAALKYAAWFPDAFYMELQR 174 Query: 178 -ANQPNMEVQVRQSVALAARLALPVVATHPIQFLSQDEFVAHEARTCIAEGEILANARRV 236 +P E V SV LA L LPVVATHP QF+S+D+F AHEAR CIA G +L + +R Sbjct: 175 LPERPEWEACVSGSVKLAEELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRP 234 Query: 237 RRFNEQQNFKTQAEMAALFADLPGAVQNTIEIAKRCNLMLTLGKPQLPNFPTPDGMTIDD 296 R F Q F MA FADLP A++NT+EIAKRCNL +TLGK LP FPTPDG+++DD Sbjct: 235 RDFTPGQFFIPPETMAERFADLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDD 294 Query: 297 FLVAETKIGLEARLKHLYPDEARREKERPRYEARLKFENDTIIKMKFPGYFLIVADFIQW 356 +L+ + GL+ R+ LYPDEA R + P Y+ RL FE + II+MKFPGYFLIV DFI W Sbjct: 295 YLIKLSNEGLQERMVQLYPDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINW 354 Query: 357 AKNNGVPVGPGRGSGAGSLVAYALSITDLDPLEYNLLFERFLNPERVSMPDFDIDFCQEG 416 AK +G PVGPGRGSGAGSLVAY+L ITDLDPL+Y LLFERFLNPERVSMPDFD+DFCQ Sbjct: 355 AKTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQSN 414 Query: 417 RDRVIQYVKDRYGKEAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKL 476 R RVI+YV+++YG EAVSQI TFGTM++K +RDVGRVL+L + CD +SKLIP + K Sbjct: 415 RGRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVGRVLELPFMLCDKLSKLIPLEANKP 474 Query: 477 VTLADAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMX---VLIAPGKLTDFCPL 533 ++L A+E EP ++E +E EE +L+ LA+++E + R +GM VLIAPGK++D+ P+ Sbjct: 475 LSLEKAMETEPQIQELIE-AEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPV 533 Query: 534 YTQGGDAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIKQLDPAMADFDLARLP 593 Y A VS YDK DVE VGLVKFDFLGL LTI++ A IK + D+ ++P Sbjct: 534 YQADESASPVSMYDKGDVEDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDI--IDVGKIP 591 Query: 594 LTDRASYDLLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFC 653 L D+ +Y + A T AVFQ ES GM+ MLK A +FE++IA V+LYRPGPMD IPDF Sbjct: 592 LDDQVAYQIFRDANTTAVFQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFV 651 Query: 654 KRKHGEKFDYPDPRTEGILSETYGIMVYQEQVMQMAQVVGGYSLGGADLLRRAMGKKKAE 713 R G++F Y P EGIL+ TYGIMVYQEQVMQ AQ++GGYSLGGADLLRRAMGKKK E Sbjct: 652 ARMKGQEFQYIHPLLEGILAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPE 711 Query: 714 EMAEHRNIFREGAAKDGLSQEKADEIFDLMEKFAGYGFNKSHAAAYALLSYHTAYLKAHH 773 EM +HR IF EGAAK G+S+EK+DEIF+ MEKFAGYGFNKSHAAAYAL+SY TA+LKAH+ Sbjct: 712 EMVKHREIFAEGAAKQGISREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHY 771 Query: 774 PAAFMAANLSLAMDDTEKIKILVEDSLDVCGLSLLPPDINLSDYRFIPVGEPGKKAVHIR 833 PA FMAA +S +D+T+++K +D G+ LPPDIN SDYRF P + + IR Sbjct: 772 PAEFMAATMSSELDNTDQLKHFYDDC-RANGIEFLPPDINESDYRFTPYPD-----MKIR 825 Query: 834 YGLGAVKGSGQSAIEAIIAARQD-GPFKDLFDFAKRVDKKQINRRTVDSLIRAGAFDCFG 892 Y LGA+KG+G++A+E+I AARQ G F L DF +RV K+ +NRRT+++LIR GAFD Sbjct: 826 YALGAIKGTGEAAVESITAARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDSIE 885 Query: 893 VDRAILQATVGLAWENAEQMEASANQVSLFGGDDSDLETPLEYVQVRPWSDKQRLTEEKT 952 +RA+L A + LA +NA+Q A+ANQ LF + +E P+ + WS+ ++L EEKT Sbjct: 886 PNRAMLLANIDLAMDNADQKAANANQGGLFDMMEDAIE-PVRLIDAPMWSESEKLAEEKT 944 Query: 953 ALGFYLSGHLFDAYEKEVRQFVRTKISSLEPSRDPRSLAGIITGIRVQMTQRGKLLIVSL 1012 +GFYLSGH F Y +EVRQ TK+ L+P +D LAG +T +R M +RGK+ VSL Sbjct: 945 VIGFYLSGHPFGPYAQEVRQIAPTKLDRLKP-QDSVRLAGFVTAVRTMMGKRGKIAFVSL 1003 Query: 1013 DDGSGTVDVTVYGELAEPNKAFFKEDELLIVQGKVSEDRFNG--GLRISAEKVMDIGAAR 1070 +D SG V++ V G+ E K D++LI++ KVS D + G GLRI A +VM + AR Sbjct: 1004 EDLSGQVEIMVGGQTLENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQTAR 1063 Query: 1071 IQYGQRVVVSLNKSVDPVHLRDTLSSYRQPQG--LPFVMKYVQSGVGCEVMLGDAWRVVP 1128 +Y + + ++L D L L++++ P +P + Y + + W V P Sbjct: 1064 ERYARSLSLALAPHHDIGGLVRLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTP 1123 Query: 1129 SDGLQVSLRESFGQEAVVVEY 1149 S L L G +V V + Sbjct: 1124 SSALFGELETLLGSRSVRVNW 1144 >NMA0632 [L] COG0587 DNA polymerase III, alpha subunit NmA Neisseria meningitidis Z2491 Length = 1144 Score = 1158 bits (2995), Expect = 0.0, Method: Compositional matrix adjust. Identities = 607/1161 (52%), Positives = 791/1161 (68%), Gaps = 29/1161 (2%) Query: 1 MTTPQFVHLRLHSEYSIVDGLVRIDDVVKAAAKDGQAALAITDLANLFGMVKFYKGARGK 60 MT P ++ LRLH+E+SI DG+VRI ++ A + G AL I+DL N FG+VKFYK R Sbjct: 1 MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDLMNEFGLVKFYKACRSA 60 Query: 61 GVKPIAGCDVWISNDDDRDKPTRLLLLVKDHHGYLQLCDLLSRAWL---TNLHRGRAELR 117 G+KPI DV I N D DKP R +L++++ GYL+L +LL+ A++ N+H AEL Sbjct: 61 GIKPIGAADVRIGNPDAPDKPFRAMLIIRNDAGYLRLSELLTAAYVGKDRNVHH--AELN 118 Query: 118 PEWLEQLRHDEGGNGLIALSGAHFGDVGIAIENGNVAAAERAAQRWSEVFPGAFYVEIQR 177 PEWLE + +GLI LSGAH+G+VG+ + NGN AA AA +++ FP AFY+E+QR Sbjct: 119 PEWLE----NGDNSGLICLSGAHYGEVGVNLLNGNEDAARAAALKYAAWFPDAFYLELQR 174 Query: 178 -ANQPNMEVQVRQSVALAARLALPVVATHPIQFLSQDEFVAHEARTCIAEGEILANARRV 236 +P E V SV LA L LPVVATHP QF+S+D+F AHEAR CIA G +L + +R Sbjct: 175 LPERPEWEACVSGSVKLAEELGLPVVATHPTQFMSRDDFNAHEARVCIAGGWVLTDKKRP 234 Query: 237 RRFNEQQNFKTQAEMAALFADLPGAVQNTIEIAKRCNLMLTLGKPQLPNFPTPDGMTIDD 296 R F Q F MA F+DLP A++NT+EIAKRCNL +TLGK LP FPTPDG+++DD Sbjct: 235 RDFTPSQFFIPPETMAERFSDLPEALENTVEIAKRCNLHITLGKNFLPLFPTPDGLSLDD 294 Query: 297 FLVAETKIGLEARLKHLYPDEARREKERPRYEARLKFENDTIIKMKFPGYFLIVADFIQW 356 +LV + GL+ R+ LYPDEA R + P Y+ RL FE + II+MKFPGYFLIV DFI W Sbjct: 295 YLVKLSNEGLQERMVQLYPDEAERAAKMPEYQERLDFELNIIIQMKFPGYFLIVQDFINW 354 Query: 357 AKNNGVPVGPGRGSGAGSLVAYALSITDLDPLEYNLLFERFLNPERVSMPDFDIDFCQEG 416 AK +G PVGPGRGSGAGSLVAY+L ITDLDPL+Y LLFERFLNPERVSMPDFD+DFCQ Sbjct: 355 AKTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLFERFLNPERVSMPDFDVDFCQAN 414 Query: 417 RDRVIQYVKDRYGKEAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKL 476 R RVI+YV+++YG EAVSQI TFGTM++K +RDVGRVL+L + CD +SKLIP + K Sbjct: 415 RGRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVGRVLELPFTLCDKLSKLIPLEANKP 474 Query: 477 VTLADAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMX---VLIAPGKLTDFCPL 533 + L DA++ EP ++E +E EE +L+ LA+++E + R +GM VLIAPGK++D+ P+ Sbjct: 475 LGLDDAMKAEPQIQELIE-AEEADELITLAKKLEDLTRGLGMHAGGVLIAPGKISDYSPV 533 Query: 534 YTQGGDAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIKQLDPAMADFDLARLP 593 Y A VS YDK DVE VGLVKFDFLGL LTI++ A IK + D+ +P Sbjct: 534 YQADESASPVSMYDKGDVEDVGLVKFDFLGLRNLTIIEMAQNNIKNTTGDIV--DVGTIP 591 Query: 594 LTDRASYDLLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMDLIPDFC 653 L D+ +Y + A T AVFQ ES GM+ MLK A +FE++IA V+LYRPGPMD IPDF Sbjct: 592 LDDQTAYQIFRDANTTAVFQFESTGMKKMLKTAHTTKFEELIAFVSLYRPGPMDNIPDFV 651 Query: 654 KRKHGEKFDYPDPRTEGILSETYGIMVYQEQVMQMAQVVGGYSLGGADLLRRAMGKKKAE 713 R G++F Y P EGIL+ TYGIMVYQEQVMQ AQ++GGYSLGGADLLRRAMGKKK E Sbjct: 652 ARMKGQEFQYIHPLLEGILAPTYGIMVYQEQVMQAAQIIGGYSLGGADLLRRAMGKKKPE 711 Query: 714 EMAEHRNIFREGAAKDGLSQEKADEIFDLMEKFAGYGFNKSHAAAYALLSYHTAYLKAHH 773 EM +HR IF EGAAK G+S+EK+DEIF+ MEKFAGYGFNKSHAAAYAL+SY TA+LKAH+ Sbjct: 712 EMVKHREIFAEGAAKQGISREKSDEIFNYMEKFAGYGFNKSHAAAYALISYQTAWLKAHY 771 Query: 774 PAAFMAANLSLAMDDTEKIKILVEDSLDVCGLSLLPPDINLSDYRFIPVGEPGKKAVHIR 833 PA FMAA +S +D+T+++K +D G+ LPPDIN SDYRF P + + IR Sbjct: 772 PAEFMAATMSSELDNTDQLKHFYDDC-RANGIEFLPPDINESDYRFTPYPD-----MKIR 825 Query: 834 YGLGAVKGSGQSAIEAIIAARQD-GPFKDLFDFAKRVDKKQINRRTVDSLIRAGAFDCFG 892 Y LGA+KG+G++A+E+I +ARQ G F L DF +RV K+ +NRRT+++LIR GAFD Sbjct: 826 YALGAIKGTGEAAVESITSARQSGGKFTGLLDFCERVGKEHMNRRTLEALIRGGAFDSIE 885 Query: 893 VDRAILQATVGLAWENAEQMEASANQVSLFGGDDSDLETPLEYVQVRPWSDKQRLTEEKT 952 +RA+L A + LA NA+Q A+ANQ LF + +E P+ + WS+ ++L EEKT Sbjct: 886 PNRAMLLANIDLAMNNADQKAANANQGGLFDMMEDAIE-PVRLIDAPMWSESEKLAEEKT 944 Query: 953 ALGFYLSGHLFDAYEKEVRQFVRTKISSLEPSRDPRSLAGIITGIRVQMTQRGKLLIVSL 1012 +GFYLSGH F Y +EVRQ K+S L+P +D LAG +T +R M +RGK+ VSL Sbjct: 945 VIGFYLSGHPFGPYAQEVRQIAPQKLSKLKP-QDSVRLAGFVTAVRTMMGKRGKIAFVSL 1003 Query: 1013 DDGSGTVDVTVYGELAEPNKAFFKEDELLIVQGKVSEDRFNG--GLRISAEKVMDIGAAR 1070 +D SG V++ V G+ E K D++LI++ KVS D + G GLRI A +VM + AR Sbjct: 1004 EDLSGQVEIMVGGQTLENCADCLKADQVLIIESKVSRDDYGGGDGLRILANQVMTLQTAR 1063 Query: 1071 IQYGQRVVVSLNKSVDPVHLRDTLSSYRQPQG--LPFVMKYVQSGVGCEVMLGDAWRVVP 1128 +Y + + ++L D L L++++ P +P + Y + + W V P Sbjct: 1064 ERYARSLSLALAPHHDIGELVQLLAAHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTP 1123 Query: 1129 SDGLQVSLRESFGQEAVVVEY 1149 S L L G +V V + Sbjct: 1124 SSALFGELETLLGSRSVRVNW 1144 >PA3640 [L] COG0587 DNA polymerase III, alpha subunit Pae Pseudomonas aeruginosa Length = 1173 Score = 1062 bits (2746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 576/1189 (48%), Positives = 783/1189 (65%), Gaps = 60/1189 (5%) Query: 3 TPQFVHLRLHSEYSIVDGLVRIDDVVKAAAKDGQAALAITDLANLFGMVKFYKGARGKGV 62 T FVHLRLH+E+S+VDGLVR+ + KA A G A+A+TD +N+ +VKFYK A G G+ Sbjct: 2 TVSFVHLRLHTEFSLVDGLVRVKPLAKAVAGLGMPAVAVTDQSNMCSLVKFYKTAMGAGI 61 Query: 63 KPIAGCDVWISNDDDRDKPTRLLLLVKDHHGYLQLCDLLSRAWLTNLHRGRAELRPEWLE 122 KPI G D+W+++ ++ +RL LL + GY L +L+SR W G + +W++ Sbjct: 62 KPICGADIWLASREEDGPLSRLSLLAMNAKGYRNLTELISRGWSEGQRNGEIIIERDWVK 121 Query: 123 QLRHDEGGNGLIALSGAHFGDVGIAIENGNVAAAERAAQRWSEVFPGAFYVEIQRANQPN 182 E GLIALS A G++G A+ +G A AE + W EVFP FYVE+QR ++ N Sbjct: 122 -----EAAEGLIALSAAKEGEIGHALLDGEEAKAEALLREWMEVFPERFYVEVQRTSRVN 176 Query: 183 MEVQVRQSVALAARLALPVVATHPIQFLSQDEFVAHEARTCIAEGEILANARRVRRFNEQ 242 E + +VALA+R P+VAT+ ++F+ Q++F AHE R CI EG L + RR R +++Q Sbjct: 177 DEEHLHAAVALASRCNAPLVATNDVRFIKQEDFEAHETRVCIGEGRTLDDPRRPRTYSDQ 236 Query: 243 QNFKTQAEMAALFADLPGAVQNTIEIAKRCNLMLTLGKPQLPNFPTPDGMTIDDFLVAET 302 Q K+ AEMA LF+DLP A++NT+EIAKRCN+ + LGK LP+FPTP+GM IDD+L + Sbjct: 237 QYLKSPAEMAELFSDLPEALENTVEIAKRCNIEVQLGKYFLPDFPTPNGMGIDDYLRHAS 296 Query: 303 KIGLEARLKHLYP-DEARREKERPRYEARLKFENDTIIKMKFPGYFLIVADFIQWAKNNG 361 GLE RL+ L P D E +R Y RL FE D II+M FPGYFLIV DFI+WAKNNG Sbjct: 297 FEGLEERLEVLLPKDTPDYEAKRQVYVDRLNFELDIIIQMGFPGYFLIVMDFIKWAKNNG 356 Query: 362 VPVGPGRGSGAGSLVAYALSITDLDPLEYNLLFERFLNPERVSMPDFDIDFCQEGRDRVI 421 VPVGPGRGSGAGSLVAY L ITDLDPL Y+LLFERFLNPER+SMPDFD+DFC EGRDRVI Sbjct: 357 VPVGPGRGSGAGSLVAYVLKITDLDPLAYDLLFERFLNPERISMPDFDVDFCMEGRDRVI 416 Query: 422 QYVKDRYGKEAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLAD 481 YV D YG+ AVSQI TFGTMAAK VRDV RV Y D +SK+IPF+ G +TL Sbjct: 417 DYVADAYGRNAVSQIITFGTMAAKAVVRDVARVQGKSYGLADRLSKMIPFEVG--MTLDK 474 Query: 482 AIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMX---VLIAPGKLTDFCPLYTQGG 538 A E+E +L++ L+++EE ++ +A ++EGI R G V+IAP KLTDF P+ Sbjct: 475 AYEQEEMLRDFLKSDEEAAEIWEMALKLEGITRGTGKHAGGVVIAPTKLTDFSPIACDEE 534 Query: 539 DAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYI------KQLDPAMADFDLARL 592 G+V+Q+DKDDVEA GLVKFDFLGL TLTI+ A+ I K L+P DF + Sbjct: 535 GGGLVTQFDKDDVEAAGLVKFDFLGLRTLTIIKWAMEIINREQAKKGLEPVNIDF----I 590 Query: 593 PLTDRASYDLLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIP 650 PL D+ +Y LL KA+T AVFQLESRGM+ ++K +PD ED+IALVAL+RPGP+ ++ Sbjct: 591 PLDDKPTYSLLQKAETTAVFQLESRGMKELIKKLKPDCLEDLIALVALFRPGPLQSGMVD 650 Query: 651 DFCKRKHGE-KFDYPDPR-----TEGILSETYGIMVYQEQVMQMAQVVGGYSLGGADLLR 704 DF RKHG + YP P E +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LR Sbjct: 651 DFINRKHGRAELSYPHPDYQYAGLEPVLKPTYGIILYQEQVMQIAQVMAGYTLGGADMLR 710 Query: 705 RAMGKKKAEEMAEHRNIFREGAAKDGLSQEKADEIFDLMEKFAGYGFNKSHAAAYALLSY 764 RAMGKKK EEMA+ R F EG +G+ + A IFDL+EKFAGYGFNKSH+AAY L+SY Sbjct: 711 RAMGKKKPEEMAKQRGGFIEGCKNNGIDADLAGNIFDLVEKFAGYGFNKSHSAAYGLVSY 770 Query: 765 HTAYLKAHHPAAFMAANLSLAMDDTEKIKILVEDSLDVCGLSLLPPDINLSDYRFIPVGE 824 TA+LK H PA FMAA L+ M +T+K+ L+E+ + L ++ PD+N S++RF V + Sbjct: 771 QTAWLKTHFPAPFMAAVLTADMQNTDKVVTLIEECRHM-KLRIVAPDVNNSEFRFT-VDD 828 Query: 825 PGKKAVHIRYGLGAVKGSGQSAIEAIIAARQD-GPFKDLFDFAKRVDKKQINRRTVDSLI 883 G+ I YGLGA+KG G+ +EAI R + GPF LFDF RVD K+IN+RT+++LI Sbjct: 829 DGR----IVYGLGAIKGVGEGPVEAITECRAEGGPFNTLFDFCDRVDLKRINKRTLEALI 884 Query: 884 RAGAFDCFG---------------VDRAILQATVGLAWENAEQMEAS--ANQVSLFGGDD 926 RAGA D G ++RA+L A + A + AEQ S + + LFGG Sbjct: 885 RAGALDRLGPHYHDELKAYQATVDLNRAVLLAAMEEAIQAAEQTARSHDSGHMDLFGGVF 944 Query: 927 SDLETPL--EYVQVRPWSDKQRLTEEKTALGFYLSGHLFDAYEKEVRQFVRTKISSLEPS 984 ++ E + + +V+ + K+RL EK LG YL+GH D YE EVR+F R +I L+P+ Sbjct: 945 AEPEADVYANHRKVKELTLKERLKGEKDTLGLYLTGHPIDEYEGEVRRFARQRIVELKPA 1004 Query: 985 RDPRSLAGIITGIRVQMTQRG-KLLIVSLDDGSGTVDVTVYGELAEPNKAFFKEDELLIV 1043 RD +++AG+I +RV ++G K+ V+LDD SG ++ +++ E ++ + D L++V Sbjct: 1005 RDTQTVAGLIVNLRVMKNKKGDKMGFVTLDDRSGRIEASLFSEAFAAAQSLLQTDALVVV 1064 Query: 1044 QGKVSEDRFNGGLRISAEKVMDIGAARIQYGQRVVVSLNKSV---DPVHLRDTLSSYRQP 1100 +G+VS+D F+GGLR+ A++VM + AR + + + L+ + D + L + R Sbjct: 1065 EGEVSQDDFSGGLRLRAKRVMSLEEARTGLAESLRMKLHADLLKGDRLRWLGELFN-RHR 1123 Query: 1101 QGLPFVMKYVQSGVGCEVMLGDAWRVVPSDGLQVSLRESFGQEAVVVEY 1149 P + Y + + G++WRV P+D L +LR+ FG++ V + Y Sbjct: 1124 GSCPITLDYTSADAKALLQFGESWRVDPADDLIQALRDQFGRDNVFLNY 1172 >STM0231 [L] COG0587 DNA polymerase III, alpha subunit Sty Salmonella typhimurium LT2 Length = 1160 Score = 1021 bits (2639), Expect = 0.0, Method: Compositional matrix adjust. Identities = 560/1174 (47%), Positives = 771/1174 (65%), Gaps = 40/1174 (3%) Query: 1 MTTPQFVHLRLHSEYSIVDGLVRIDDVVKAAAKDGQAALAITDLANLFGMVKFYKGARGK 60 M+ P+FVHLR+HS+YS++DGL + +VK AA G ALAITD NL G+VKFY G Sbjct: 1 MSEPRFVHLRVHSDYSMIDGLAKTGPLVKKAASLGMPALAITDFTNLCGLVKFYGAGHGA 60 Query: 61 GVKPIAGCDVWISNDDDRDKPTRLLLLVKDHHGYLQLCDLLSRAWLTNLHRGRAELRPEW 120 G+KPI G D + N+ D+ T L +L ++ GY L L+S+A+ + +W Sbjct: 61 GIKPIVGADFNVHNELLGDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIERDW 120 Query: 121 LEQLRHDEGGNGLIALSGAHFGDVGIAIENGNVAAAERAAQRWSEVFPGAFYVEIQRANQ 180 L +L+ GLI LSG GDVG + GN A E + FP +++E+ R + Sbjct: 121 LVELK-----EGLILLSGGRMGDVGRCLLRGNQALVEECVAFYEAHFPDRYFLELIRTGR 175 Query: 181 PNMEVQVRQSVALAARLALPVVATHPIQFLSQDEFVAHEARTCIAEGEILANARRVRRFN 240 + E + +V LA LPVVAT+ ++FL D+F AHE R I +G L + +R R ++ Sbjct: 176 QDEETYLHAAVELAEARGLPVVATNDVRFLESDDFDAHEIRVAIHDGFTLDDPKRPRNYS 235 Query: 241 EQQNFKTQAEMAALFADLPGAVQNTIEIAKRCNLMLTLGKPQLPNFPTPDGMTIDDFLVA 300 QQ +++ EM LF+D+P A++NT+EIAKRCN+ + LG+ LP FPT D MT +D+LV Sbjct: 236 PQQYMRSEEEMCELFSDIPEALENTVEIAKRCNVTVRLGEYFLPQFPTGD-MTTEDYLVK 294 Query: 301 ETKIGLEARLKHLYPDEARREKERPRYEARLKFENDTIIKMKFPGYFLIVADFIQWAKNN 360 + K GLE RL L+PDE R+K RP Y+ RL E I +M FPGYFLIV +FIQW+K+N Sbjct: 295 KAKEGLEERLAFLFPDEEERKKRRPEYDERLDIELQVINQMGFPGYFLIVMEFIQWSKDN 354 Query: 361 GVPVGPGRGSGAGSLVAYALSITDLDPLEYNLLFERFLNPERVSMPDFDIDFCQEGRDRV 420 GVPVGPGRGSGAGSLVAYAL ITDLDPLE++LLFERFLNPERVSMPDFD+DFC E RD+V Sbjct: 355 GVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQV 414 Query: 421 IQYVKDRYGKEAVSQIATFGTMAAKGAVRDVGRVLDLGYNFCDGISKLIPFKPGKLVTLA 480 I++V D YG++AVSQI TFGTMAAK +RDVGRVL Y F D ISKL+P PG +TLA Sbjct: 415 IEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLVPPDPG--MTLA 472 Query: 481 DAIEEEPLLKERLENEEEVKQLMGLAQQVEGIARNIGMX---VLIAPGKLTDFCPLYTQG 537 A E EP L E E +EEV+ L+ +A+++EG+ RN G V+IAP K+TDF PLY Sbjct: 473 KAFEAEPQLPEIYEADEEVRALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDE 532 Query: 538 GDAGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDRAVRYIKQLDPAMAD--FDLARLPLT 595 V+Q+DK DVE GLVKFDFLGL TLTI++ A+ I + + D+A +PL Sbjct: 533 EGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLD 592 Query: 596 DRASYDLLTKAKTVAVFQLESRGMQGMLKDARPDRFEDIIALVALYRPGPMD--LIPDFC 653 D+ S+D+L +++T AVFQLESRGM+ ++K +PD FED+IALVAL+RPGP+ ++ +F Sbjct: 593 DKKSFDMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFI 652 Query: 654 KRKHG-EKFDYPDPRTEG-----ILSETYGIMVYQEQVMQMAQVVGGYSLGGADLLRRAM 707 RKHG E+ YPD + + +L TYGI++YQEQVMQ+AQV+ GY+LGGAD+LRRAM Sbjct: 653 DRKHGREELSYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAM 712 Query: 708 GKKKAEEMAEHRNIFREGAAKDGLSQEKADEIFDLMEKFAGYGFNKSHAAAYALLSYHTA 767 GKKK EEMA+ R++F EGA K+G+ E A +IFDL+EKFAGYGFNKSH+AAYAL+SY T Sbjct: 713 GKKKPEEMAKQRSVFEEGAKKNGIDGELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTL 772 Query: 768 YLKAHHPAAFMAANLSLAMDDTEKIKILVEDSLDVCGLSLLPPDINLSDYRFIPVGEPGK 827 +LKAH+PA FMAA ++ MD+TEK+ LV++ + GL +LPPDIN Y F V + G+ Sbjct: 773 WLKAHYPAEFMAAVMTADMDNTEKVVGLVDECWRM-GLKILPPDINSGLYHF-HVNDEGE 830 Query: 828 KAVHIRYGLGAVKGSGQSAIEAIIAAR-QDGPFKDLFDFAKRVDKKQINRRTVDSLIRAG 886 I YG+GA+KG G+ IEAII AR Q G F++LFD R D K++NRR ++ LI +G Sbjct: 831 ----IVYGIGAIKGVGEGPIEAIIDARNQGGYFRELFDLCARTDTKKLNRRVLEKLIMSG 886 Query: 887 AFDCFGVDRAILQATVGLAWENAEQMEASA--NQVSLFGGDDSDLE-TPLEYVQVRPWSD 943 AFD G RA L ++G A + A+Q + Q +FG + E Y +PW + Sbjct: 887 AFDRLGPHRAALMNSLGDALKAADQHAKAEAIGQTDMFGVLAEEPEQIEQSYASCQPWPE 946 Query: 944 KQRLTEEKTALGFYLSGHLFDAYEKEVRQFV-RTKISSLEPSRDPR--SLAGIITGIRVQ 1000 + L E+ LG YL+GH + Y KE+ ++V ++ + P+ + + AG++ RV Sbjct: 947 QVVLDGERETLGLYLTGHPINQYLKEIERYVGGVRLKDMHPTERGKVTTAAGLVIAARVM 1006 Query: 1001 MTQRG-KLLIVSLDDGSGTVDVTVYGELAEPNKAFFKEDELLIVQGKVSEDRFNGGLRIS 1059 +T+RG ++ I +LDD SG ++V ++ + + + ++D +LIV G+VS D F+GGL+++ Sbjct: 1007 VTKRGNRIGICTLDDRSGRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMT 1066 Query: 1060 AEKVMDIGAARIQYGQRVVVSL-NKSVDPV---HLRDTLSSYRQPQGLPFVMKYVQSGVG 1115 A +VMDI AR +Y + + +SL ++ +D LR +L +R +P + Y ++ Sbjct: 1067 AREVMDIDEAREKYARGLAISLTDRQIDDQLLNRLRQSLEPHRSGT-IPVHLYYQRADAR 1125 Query: 1116 CEVMLGDAWRVVPSDGLQVSLRESFGQEAVVVEY 1149 + G WRV PSD L LR G E V +E+ Sbjct: 1126 ARLRFGATWRVSPSDRLLNDLRGLIGSEQVELEF 1159