BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0031.p (481 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM3551 [E] COG0405 Gamma-glutamyltransferase Sty Salmonella typ... 605 e-173 Zggt [E] COG0405 Gamma-glutamyltransferase EcZ Escherichia coli ... 594 e-169 ECs4293 [E] COG0405 Gamma-glutamyltransferase Ecs Escherichia co... 594 e-169 ggt [E] COG0405 Gamma-glutamyltransferase Eco Escherichia coli K12 594 e-169 HP1118 [E] COG0405 Gamma-glutamyltransferase Hpy Helicobacter py... 489 e-138 >STM3551 [E] COG0405 Gamma-glutamyltransferase Sty Salmonella typhimurium LT2 Length = 580 Score = 605 bits (1561), Expect = e-173, Method: Compositional matrix adjust. Identities = 294/483 (60%), Positives = 372/483 (77%), Gaps = 2/483 (0%) Query: 1 MMIHDAKTGKNVALDFREMAPAKASRDMYLDDKGNVAPGRSLYTHLAVGVPGTVAGLTHA 60 M+ K G A+DFREMAPA A+RDM+LDD+GN +SL +HLA G PGTVAG + A Sbjct: 98 FMLLRTKDGATTAIDFREMAPAGATRDMFLDDQGNADAKKSLTSHLASGTPGTVAGFSLA 157 Query: 61 LQKYGTMKLSDVIAPAVKLAEKGYEVSPSLALILAAE-RDHLGQWDSSKAIFFKDGRPLQ 119 L+KYGTM L+ V+ PA+KLAE+G+ V+ +LA L + + ++SKAIF+KDG PL+ Sbjct: 158 LEKYGTMPLNKVVRPAMKLAEEGFVVNDALANDLKTYGSEVILNHENSKAIFWKDGEPLK 217 Query: 120 AGEKLVQKDLAKSLKLIGKKGPSVFYEGEIGKKIVAEMDKHNGLITAADLKNYKVVEREP 179 G+KLVQK+LAKSL++I + GP FY+G I +I EM K+ GL+T DL NYK VER P Sbjct: 218 KGDKLVQKNLAKSLEMIAENGPDAFYKGAIADQIAGEMQKNGGLMTKEDLANYKAVERTP 277 Query: 180 VVGNYRGYQVMSMPPPSSGGIHIIQMMNILERYPLKQYGADSAQTIHLMAEAMKLAYADR 239 + G+YRGYQV SMPPPSSGGIHI+Q++NILE + +K+YG SA + +MAEA K AYADR Sbjct: 278 ISGDYRGYQVFSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADR 337 Query: 240 AEYLGDPDFNKVPVKGLTSRAYADELAKKINPDRATPSAEIKPGKPQPYESDQTTHFSVA 299 +EYLGDPDF KVP + LT +AYA LA +I+ ++A PS++IKPGK PYES+QTTHFSV Sbjct: 338 SEYLGDPDFVKVPWQALTHKAYAKTLADQIDINKAKPSSQIKPGKLAPYESNQTTHFSVV 397 Query: 300 DNKGNLIATTYTLNLNFGSGIVAGGTGITLNNEMDDFSAKPGVPNAFGLVGGEANAVGPA 359 D GN +A TYTLN FG+GIVAG TGI LNN+MDDFSAKPGVPN +GLVGG+ANAVGP Sbjct: 398 DKDGNAVAVTYTLNTTFGTGIVAGNTGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPK 457 Query: 360 KRPLSSMSPTFVLKDGKPFLVTGSPGGSRIITTTMQTILNVIEHDMNVAEATVTPRVHHQ 419 KRPLSSMSPT V+K+GK +LVTGSPGGSRIITT +Q ++N I+ MNVAEAT PR HHQ Sbjct: 458 KRPLSSMSPTIVVKEGKTWLVTGSPGGSRIITTVLQMVVNSIDFGMNVAEATNAPRFHHQ 517 Query: 420 WAPDQLRIEKGISADTIRILQDKGQKISVQPSMGRTQTIQI-KDGMFYGYSDPRNPDGRT 478 W PD+LR+EKG S DT+++L+ KGQK++++ +MG TQ+I + DG YG SDPR+ D T Sbjct: 518 WLPDELRVEKGFSPDTLKLLEQKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLT 577 Query: 479 LGF 481 G+ Sbjct: 578 AGY 580 >Zggt [E] COG0405 Gamma-glutamyltransferase EcZ Escherichia coli O157:H7 EDL933 Length = 581 Score = 594 bits (1531), Expect = e-169, Method: Compositional matrix adjust. Identities = 290/483 (60%), Positives = 370/483 (76%), Gaps = 2/483 (0%) Query: 1 MMIHDAKTGKNVALDFREMAPAKASRDMYLDDKGNVAPGRSLYTHLAVGVPGTVAGLTHA 60 M+ +K G A+DFREMAPAKA+RDM+LDD+GN +SL +HLA G PGTVAG + A Sbjct: 99 FMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLA 158 Query: 61 LQKYGTMKLSDVIAPAVKLAEKGYEVSPSLALILAAE-RDHLGQWDSSKAIFFKDGRPLQ 119 L KYGTM L+ V+ PA KLA G+ V+ LA L + L ++SKAIF+K+G PL+ Sbjct: 159 LDKYGTMPLNKVVQPAFKLARDGFIVNDELADDLKTYGSEVLPNHENSKAIFWKEGEPLK 218 Query: 120 AGEKLVQKDLAKSLKLIGKKGPSVFYEGEIGKKIVAEMDKHNGLITAADLKNYKVVEREP 179 G+KLVQ +LAKSL++I + GP FY+G I ++I EM K+ GLIT DL YK VER P Sbjct: 219 KGDKLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTP 278 Query: 180 VVGNYRGYQVMSMPPPSSGGIHIIQMMNILERYPLKQYGADSAQTIHLMAEAMKLAYADR 239 + G+YRGYQV SMPPPSSGGIHI+Q++NILE + +K+YG SA + +MAEA K AYADR Sbjct: 279 ISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADR 338 Query: 240 AEYLGDPDFNKVPVKGLTSRAYADELAKKINPDRATPSAEIKPGKPQPYESDQTTHFSVA 299 +EYLGDPDF KVP + LT++AYA +A++I+ ++A PS+EI+PGK PYES+QTTH+SV Sbjct: 339 SEYLGDPDFVKVPWQALTNKAYAKSIAEQIDINKAKPSSEIRPGKLAPYESNQTTHYSVV 398 Query: 300 DNKGNLIATTYTLNLNFGSGIVAGGTGITLNNEMDDFSAKPGVPNAFGLVGGEANAVGPA 359 D GN +A TYTLN FG+GIVAG +GI LNN+MDDFSAKPGVPN +GLVGG+ANAVGP Sbjct: 399 DKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPN 458 Query: 360 KRPLSSMSPTFVLKDGKPFLVTGSPGGSRIITTTMQTILNVIEHDMNVAEATVTPRVHHQ 419 KRPLSSMSPT V+KDGK +LVTGSPGGS IITT +Q ++N I++ MNVAEAT PR HHQ Sbjct: 459 KRPLSSMSPTIVVKDGKTWLVTGSPGGSLIITTVLQMVVNSIDYGMNVAEATNAPRFHHQ 518 Query: 420 WAPDQLRIEKGISADTIRILQDKGQKISVQPSMGRTQTIQI-KDGMFYGYSDPRNPDGRT 478 W PD+LR+EKG S DT+++L+ KGQK++++ +MG TQ+I + DG YG SDPR+ D T Sbjct: 519 WLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLT 578 Query: 479 LGF 481 G+ Sbjct: 579 AGY 581 >ECs4293 [E] COG0405 Gamma-glutamyltransferase Ecs Escherichia coli O157:H7 Length = 581 Score = 594 bits (1531), Expect = e-169, Method: Compositional matrix adjust. Identities = 290/483 (60%), Positives = 370/483 (76%), Gaps = 2/483 (0%) Query: 1 MMIHDAKTGKNVALDFREMAPAKASRDMYLDDKGNVAPGRSLYTHLAVGVPGTVAGLTHA 60 M+ +K G A+DFREMAPAKA+RDM+LDD+GN +SL +HLA G PGTVAG + A Sbjct: 99 FMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLA 158 Query: 61 LQKYGTMKLSDVIAPAVKLAEKGYEVSPSLALILAAE-RDHLGQWDSSKAIFFKDGRPLQ 119 L KYGTM L+ V+ PA KLA G+ V+ LA L + L ++SKAIF+K+G PL+ Sbjct: 159 LDKYGTMPLNKVVQPAFKLARDGFIVNDELADDLKTYGSEVLPNHENSKAIFWKEGEPLK 218 Query: 120 AGEKLVQKDLAKSLKLIGKKGPSVFYEGEIGKKIVAEMDKHNGLITAADLKNYKVVEREP 179 G+KLVQ +LAKSL++I + GP FY+G I ++I EM K+ GLIT DL YK VER P Sbjct: 219 KGDKLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTP 278 Query: 180 VVGNYRGYQVMSMPPPSSGGIHIIQMMNILERYPLKQYGADSAQTIHLMAEAMKLAYADR 239 + G+YRGYQV SMPPPSSGGIHI+Q++NILE + +K+YG SA + +MAEA K AYADR Sbjct: 279 ISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADR 338 Query: 240 AEYLGDPDFNKVPVKGLTSRAYADELAKKINPDRATPSAEIKPGKPQPYESDQTTHFSVA 299 +EYLGDPDF KVP + LT++AYA +A++I+ ++A PS+EI+PGK PYES+QTTH+SV Sbjct: 339 SEYLGDPDFVKVPWQALTNKAYAKSIAEQIDINKAKPSSEIRPGKLAPYESNQTTHYSVV 398 Query: 300 DNKGNLIATTYTLNLNFGSGIVAGGTGITLNNEMDDFSAKPGVPNAFGLVGGEANAVGPA 359 D GN +A TYTLN FG+GIVAG +GI LNN+MDDFSAKPGVPN +GLVGG+ANAVGP Sbjct: 399 DKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPN 458 Query: 360 KRPLSSMSPTFVLKDGKPFLVTGSPGGSRIITTTMQTILNVIEHDMNVAEATVTPRVHHQ 419 KRPLSSMSPT V+KDGK +LVTGSPGGS IITT +Q ++N I++ MNVAEAT PR HHQ Sbjct: 459 KRPLSSMSPTIVVKDGKTWLVTGSPGGSLIITTVLQMVVNSIDYGMNVAEATNAPRFHHQ 518 Query: 420 WAPDQLRIEKGISADTIRILQDKGQKISVQPSMGRTQTIQI-KDGMFYGYSDPRNPDGRT 478 W PD+LR+EKG S DT+++L+ KGQK++++ +MG TQ+I + DG YG SDPR+ D T Sbjct: 519 WLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLT 578 Query: 479 LGF 481 G+ Sbjct: 579 AGY 581 >ggt [E] COG0405 Gamma-glutamyltransferase Eco Escherichia coli K12 Length = 580 Score = 594 bits (1531), Expect = e-169, Method: Compositional matrix adjust. Identities = 289/483 (59%), Positives = 370/483 (76%), Gaps = 2/483 (0%) Query: 1 MMIHDAKTGKNVALDFREMAPAKASRDMYLDDKGNVAPGRSLYTHLAVGVPGTVAGLTHA 60 M+ +K G A+DFREMAPAKA+RDM+LDD+GN +SL +HLA G PGTVAG + A Sbjct: 98 FMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLA 157 Query: 61 LQKYGTMKLSDVIAPAVKLAEKGYEVSPSLALILAAE-RDHLGQWDSSKAIFFKDGRPLQ 119 L KYGTM L+ V+ PA KLA G+ V+ +LA L + L ++SKAIF+K+G PL+ Sbjct: 158 LDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLK 217 Query: 120 AGEKLVQKDLAKSLKLIGKKGPSVFYEGEIGKKIVAEMDKHNGLITAADLKNYKVVEREP 179 G+ LVQ +LAKSL++I + GP FY+G I ++I EM K+ GLIT DL YK VER P Sbjct: 218 KGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTP 277 Query: 180 VVGNYRGYQVMSMPPPSSGGIHIIQMMNILERYPLKQYGADSAQTIHLMAEAMKLAYADR 239 + G+YRGYQV SMPPPSSGGIHI+Q++NILE + +K+YG SA + +MAEA K AYADR Sbjct: 278 ISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADR 337 Query: 240 AEYLGDPDFNKVPVKGLTSRAYADELAKKINPDRATPSAEIKPGKPQPYESDQTTHFSVA 299 +EYLGDPDF KVP + LT++AYA +A +I+ ++A PS+EI+PGK PYES+QTTH+SV Sbjct: 338 SEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTTHYSVV 397 Query: 300 DNKGNLIATTYTLNLNFGSGIVAGGTGITLNNEMDDFSAKPGVPNAFGLVGGEANAVGPA 359 D GN +A TYTLN FG+GIVAG +GI LNN+MDDFSAKPGVPN +GLVGG+ANAVGP Sbjct: 398 DKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPN 457 Query: 360 KRPLSSMSPTFVLKDGKPFLVTGSPGGSRIITTTMQTILNVIEHDMNVAEATVTPRVHHQ 419 KRPLSSMSPT V+KDGK +LVTGSPGGSRIITT +Q ++N I++ +NVAEAT PR HHQ Sbjct: 458 KRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGLNVAEATNAPRFHHQ 517 Query: 420 WAPDQLRIEKGISADTIRILQDKGQKISVQPSMGRTQTIQI-KDGMFYGYSDPRNPDGRT 478 W PD+LR+EKG S DT+++L+ KGQK++++ +MG TQ+I + DG YG SDPR+ D T Sbjct: 518 WLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLT 577 Query: 479 LGF 481 G+ Sbjct: 578 AGY 580 >HP1118 [E] COG0405 Gamma-glutamyltransferase Hpy Helicobacter pylori 26695 Length = 567 Score = 489 bits (1260), Expect = e-138, Method: Compositional matrix adjust. Identities = 252/477 (52%), Positives = 325/477 (68%), Gaps = 7/477 (1%) Query: 2 MIHDAKTGKNVALDFREMAPAKASRDMYLDDKGNVAPGRSLYTHLAVGVPGTVAGLTHAL 61 +IH A G+NVALDFRE AP KA+++M+LD +GNV P S +LA GVPGTVAG+ L Sbjct: 89 VIHLA-NGENVALDFREKAPLKATKNMFLDKQGNVVPKLSEDGYLAAGVPGTVAGMEAML 147 Query: 62 QKYGTMKLSDVIAPAVKLAEKGYEVSPSLALILAAERDHLGQWDSSKAIFFKDGR-PLQA 120 +KYGT KLS +I PA+KLAE GY +S A L R+ ++ SSK FFK G Q Sbjct: 148 KKYGTKKLSQLIDPAIKLAENGYAISQRQAETLKEARERFLKYSSSKKYFFKKGHLDYQE 207 Query: 121 GEKLVQKDLAKSLKLIGKKGPSVFYEGEIGKKIVAEMDKHNGLITAADLKNYKVVEREPV 180 G+ VQKDLAK+L I G FY+G++ + I +M K+ G+IT DL +Y V R+PV Sbjct: 208 GDLFVQKDLAKTLNQIKTLGAKGFYQGQVAELIEKDMKKNGGIITKEDLASYNVKWRKPV 267 Query: 181 VGNYRGYQVMSMPPPSSGGIHIIQMMNILERYPLKQYGADSAQTIHLMAEAMKLAYADRA 240 VG+YRGY+++SM PPSSGG H+IQ++N++E L G +++ IH+ AEAM+ AYADR+ Sbjct: 268 VGSYRGYKIISMSPPSSGGTHLIQILNVMENADLSALGYGASKNIHIAAEAMRQAYADRS 327 Query: 241 EYLGDPDFNKVPVKGLTSRAYADELAKKINPDRATPSAEIKPGKPQPYESDQTTHFSVAD 300 Y+GD DF VPV L ++AYA ++ I PD TPS++IKPG Q +E TTH+SVAD Sbjct: 328 VYMGDADFVSVPVDKLINKAYAKKIFDTIQPDTVTPSSQIKPGMGQLHEGSNTTHYSVAD 387 Query: 301 NKGNLIATTYTLNLNFGSGIVAGGTGITLNNEMDDFSAKPGVPNAFGLVGGEANAVGPAK 360 GN ++ TYT+N ++GS G G LNNEMDDFS KPG PN +GLVGG+ANA+ K Sbjct: 388 RWGNAVSVTYTINASYGSAASIDGAGFLLNNEMDDFSIKPGNPNLYGLVGGDANAIEANK 447 Query: 361 RPLSSMSPTFVLKDGKPFLVTGSPGGSRIITTTMQTILNVIEHDMNVAEATVTPRVHHQW 420 RPLSSMSPT VLK+ K FLV GSPGGSRIITT +Q I NVI+++MN++EA PR H QW Sbjct: 448 RPLSSMSPTIVLKNNKVFLVVGSPGGSRIITTVLQVISNVIDYNMNISEAVSAPRFHMQW 507 Query: 421 APDQLRIEK-GISADTIRILQDKGQKISVQPSMGRTQTIQI----KDGMFYGYSDPR 472 PD+LRIEK G+ AD L G +I +P MG IQ+ K +FYG +DPR Sbjct: 508 LPDELRIEKFGMPADVKDNLTKMGYQIVTKPVMGDVNAIQVLPKTKGSVFYGSTDPR 564