BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0746.p (289 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll1685 [GEPR] COG0477 Permeases of the major facilitator superf... 224 1e-58 mlr2429 [GEPR] COG0477 Permeases of the major facilitator superf... 98 2e-20 BS_ycxA [GEPR] COG0477 Permeases of the major facilitator superf... 71 3e-12 yhjX [GEPR] COG0477 Permeases of the major facilitator superfami... 66 1e-10 ZyhjX [GEPR] COG0477 Permeases of the major facilitator superfam... 65 1e-10 >mll1685 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 469 Score = 224 bits (572), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 136/274 (49%), Positives = 176/274 (64%), Gaps = 11/274 (4%) Query: 8 HSAFKDDPKKDP--GNNF-----GADSSYAVVRLLITLVLMVIGASGMYVVAVVLPAVQA 60 + F+D ++ P +F G DSSYA +RL I++VL IGA GM+ V VVLPAVQ Sbjct: 49 EAGFRDRRQETPLTRTDFSRPSPGIDSSYAWMRLAISMVLATIGAVGMWAVVVVLPAVQG 108 Query: 61 EFGVARGVASMPYTLSMIGFGIGGMLMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNI 120 EFGV R ASMPYT +M+GF G +L+G+ DR G IP L+ +V L G +LA ++ +I Sbjct: 109 EFGVDRAAASMPYTATMVGFAAGNVLVGRAIDRMGYWIPALISSVALSAGLLLAALSTSI 168 Query: 121 IVFTLAHGLLIGLCGSSATFSPLIADTSLWFVRRRGIAVAVCASGNYLGGAIWPPIVQHF 180 + FTLA G+LIG+ G+S F PLIAD S WF RRRG+AV A+GNYL GA+WP I+ Sbjct: 169 LQFTLAQGVLIGV-GTSVIFGPLIADISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTL 227 Query: 181 VDTVGWRQTYFGLGVVCFIVMGGLALLMRRRPPVAVAAAARNGVSLTSERPFGLPMGKAQ 240 + GWR TY +G+ C + M L L++RR P A A + S+ +P + Q Sbjct: 228 IKAEGWRFTYAAIGIFCLVTMVPLVLMLRRGAPEATADGSPGSRSV---QPIPMSPAAMQ 284 Query: 241 LLLCVAGIACCVAMAMPQVHIVAYCGDLGYGAXH 274 LL VAG+ CCVAM+MPQVHIVAYC DLGYG H Sbjct: 285 GLLVVAGLGCCVAMSMPQVHIVAYCMDLGYGMAH 318 >mlr2429 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 400 Score = 98.2 bits (243), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 67/219 (30%), Positives = 118/219 (53%), Gaps = 2/219 (0%) Query: 48 MYVVAVVLPAVQAEFGVARGVASMPYTLSMIGFGIGGMLMGKLADRFGVMIPLLVGAVCL 107 M+ +A+ L + + +R S TL+ + G+GG G L+DRFG I + +GAV L Sbjct: 24 MFSLAIFLEPMALDTQWSRAGISSAMTLNFLVMGLGGFAWGALSDRFGARIVVAIGAVLL 83 Query: 108 GLGFILAGMAPNIIVFTLAHGLLIGLCGSSATFSPLIADTSLWFVRRRGIAVAVCASGNY 167 GL ++A A +++ F +++G+L+GL +SA F+P+IA T+ WF R +AV++ ++G Sbjct: 84 GLALVVASRAGSLLTFQISYGVLVGLA-ASAFFAPMIALTTAWFDTNRSLAVSLVSAGMG 142 Query: 168 LGGAIWPPIVQHFVDTVGWRQTYFGLGVVCFIVMGGLALLMRRRPPVAVAAAARNGVSLT 227 + P + + WR F +G++ ++++ LL+R+ P AVAA A V+ Sbjct: 143 VAPMTISPFARWLISAYEWRTAMFDIGIMAWVLLLPAVLLVRQPPKPAVAAGASAPVAEG 202 Query: 228 SERPFGLPMGKAQLL-LCVAGIACCVAMAMPQVHIVAYC 265 + + Q + L + CC A + P H+V+Y Sbjct: 203 AGMSVAQALRSPQFIVLGLTFFTCCAAHSGPIFHMVSYA 241 >BS_ycxA [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 409 Score = 70.9 bits (172), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 62/217 (28%), Positives = 98/217 (45%), Gaps = 7/217 (3%) Query: 54 VLPAVQAEFGVARGVASMPYTLSMIGFGIGGMLMGKLADRFGVMIPLLVGAVCLGLGFIL 113 +LP A F R + S+ ++ MI GI +G DRF V + +GAVC+ F++ Sbjct: 33 MLPMADA-FHADRSLISVSVSIFMITTGIVQFFVGFFIDRFSVRKIMALGAVCISASFLV 91 Query: 114 AGMAPNIIVFTLAHGLLIGLCGSSATFSPLIADTSLWFVRRRGIAVAVCASGNYLGGAIW 173 +PN+ VF+ +G+L G+ S A S WF +G+A+A+ + N G + Sbjct: 92 LPYSPNVHVFSAIYGVLGGIGYSCAVGVTTQYFISCWFDTHKGLALAILTNANSAGLVVS 151 Query: 174 PPIVQHFVD-TVGWRQTYFGLGVVCFIVMGGLALLMRRRPPVAVAAAARNGVSLTSERPF 232 PP + GW+ TY LG+V V+ L + + PP A A + R F Sbjct: 152 PPPIWAAAPYHAGWQSTYTILGIVMAAVLVPLLVFGMKHPPHAQAETVKKSY---DWRGF 208 Query: 233 GLPMGKAQL--LLCVAGIACCVAMAMPQVHIVAYCGD 267 M +++L +L C M + H+V D Sbjct: 209 WNVMKQSRLIHILYFGVFTCGFTMGIIDAHLVPILKD 245 >yhjX [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 402 Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 63/253 (24%), Positives = 115/253 (45%), Gaps = 13/253 (5%) Query: 27 SSYAVVR--LLITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVASMPYTLSMIGFGIGG 84 S+Y R LI ++ +Y ++ A+ A+ + + L +G I Sbjct: 4 SNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAPVSQVAFSFGLLSLGLAISS 63 Query: 85 MLMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLLIGLCGSSATFSPLI 144 + GKL +RFGV + + LGLGF L + N+++ L+ G+L+GL A + + Sbjct: 64 SVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNLMMLWLSAGVLVGLA-DGAGYLLTL 122 Query: 145 ADTSLWFVRRRGIAVAVCASGNY-LGGAIWPPIVQHFVDTVGWRQTYFGLGVVCFIVMGG 203 ++ WF R+G+ ++ A G+Y LG + I ++TVG +T+ G + +++ Sbjct: 123 SNCVKWFPERKGL-ISAFAIGSYGLGSLGFKFIDTQLLETVGLEKTFVIWGAIALLMIVF 181 Query: 204 LALLMRRRPPVAVAAAARNGVSLTSERPFGLPMGKAQL-LLCVAGIACCVAMAMPQVHIV 262 A LM+ P V + NGV + + M K Q +L V + C M ++++ Sbjct: 182 GATLMKDAPKQEVKTS--NGV-VEKDYTLAESMRKPQYWMLAVMFLTAC----MSGLYVI 234 Query: 263 AYCGDLGYGAXHI 275 D+ H+ Sbjct: 235 GVAKDIAQSLAHL 247 >ZyhjX [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 400 Score = 65.5 bits (158), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 63/253 (24%), Positives = 115/253 (45%), Gaps = 13/253 (5%) Query: 27 SSYAVVR--LLITLVLMVIGASGMYVVAVVLPAVQAEFGVARGVASMPYTLSMIGFGIGG 84 S+Y R LI ++ +Y ++ A+ A+ + + L +G I Sbjct: 4 SNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAPVSQVAFSFGLLSLGLAISS 63 Query: 85 MLMGKLADRFGVMIPLLVGAVCLGLGFILAGMAPNIIVFTLAHGLLIGLCGSSATFSPLI 144 + GKL +RFGV + + LGLGF L + N+++ L+ G+L+GL A + + Sbjct: 64 SVAGKLQERFGVKRVTIASGILLGLGFFLTAHSDNLMMLWLSAGVLVGLA-DGAGYLLTL 122 Query: 145 ADTSLWFVRRRGIAVAVCASGNY-LGGAIWPPIVQHFVDTVGWRQTYFGLGVVCFIVMGG 203 ++ WF R+G+ ++ A G+Y LG + I ++TVG +T+ G + +++ Sbjct: 123 SNCVKWFPERKGL-ISAFAIGSYGLGSLGFKFIDTQLLETVGLEKTFVIWGAIALVMIVF 181 Query: 204 LALLMRRRPPVAVAAAARNGVSLTSERPFGLPMGKAQL-LLCVAGIACCVAMAMPQVHIV 262 A LM+ P V + NGV + + M K Q +L V + C M ++++ Sbjct: 182 GATLMKDAPKQEVKTS--NGV-VEKDYTLAESMRKPQYWMLAVMFLTAC----MSGLYVI 234 Query: 263 AYCGDLGYGAXHI 275 D+ H+ Sbjct: 235 GVAKDIAQSLAHL 247