BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0739.p (583 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value yeaG [T] COG2766 Putative Ser protein kinase Eco Escherichia col... 865 0.0 ZyeaG [T] COG2766 Putative Ser protein kinase EcZ Escherichia co... 865 0.0 ECs2492 [T] COG2766 Putative Ser protein kinase Ecs Escherichia ... 865 0.0 STM1285 [T] COG2766 Putative Ser protein kinase Sty Salmonella t... 864 0.0 PA0588 [T] COG2766 Putative Ser protein kinase Pae Pseudomonas a... 863 0.0 >yeaG [T] COG2766 Putative Ser protein kinase Eco Escherichia coli K12 Length = 644 Score = 865 bits (2235), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/550 (73%), Positives = 476/550 (86%), Gaps = 4/550 (0%) Query: 1 MDIYSSFASRFDKTREEEFSLEEYLSLCKNDPAVYASAAERMLMAIGEPEKVDTREDPRL 60 M+I+ + R++ ++EEF+L+E+L+ C+ D + YA+AAER+LMAIGEP VDT ++PRL Sbjct: 1 MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAQEPRL 60 Query: 61 SRLFANKVIKVYPAFKEFYGAEEVIEQVVAYFRHASQGLEEKKQILYLLGPVGGGKSSIA 120 SRLF+N+VI YPAF+EFYG E+ IEQ+V+Y +HA+QGLEEKKQILYLLGPVGGGKSS+A Sbjct: 61 SRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLA 120 Query: 121 ERLKQLMEHIPFYSIKG----SPVNESPFGLFDYEEDGQILEEQFGIPRRYLKSILSPWA 176 ERLK LM+ +P Y + SPVN+ PF LF+ +ED QILE+++GIPRRYL +I+SPWA Sbjct: 121 ERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQILEKEYGIPRRYLGTIMSPWA 180 Query: 177 VKRLHEFNGDIRQFRVVKRYPSILRQIAISKTEPGDENNQDISTLVGKVDIRKLEQYSQD 236 KRLHEF GDI +FRVVK +PSIL+QIAI+KTEPGDENNQDIS LVGKVDIRKLE Y+Q+ Sbjct: 181 AKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDENNQDISALVGKVDIRKLEHYAQN 240 Query: 237 DADAYSYSGGLCLSNQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIIL 296 D DAY YSG LC +NQG++EFVEMFKAPIKVLHPLLTATQEGN+ GTEG A+PF+GIIL Sbjct: 241 DPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIIL 300 Query: 297 AHSNESEWKAFRNNKNNEALLDRIYIVKVPYCLRVSEEIRIYEKLLRTSSLANATCAPGT 356 AHSNESEW FRNNKNNEA LDR+YIVKVPYCLR+SEEI+IYEKLL S L +A CAPGT Sbjct: 301 AHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGT 360 Query: 357 LKMMAQFSILTRLGEPENSSLISKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGIS 416 L+ +++FSIL+RL EPENSS+ SKM+VYDGE+LKDTDPKAKSYQEYRDYAGVDEGM G+S Sbjct: 361 LETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLS 420 Query: 417 TRFAFKILSRVFNFDTTEIAANPVHLMYILEQQIEREQFPPEQEQKYLSFVKDTLASRYA 476 TRFAFKILSRVFNFD E+AANPVHL Y+LEQQIEREQFP EQ ++YL F+K L +YA Sbjct: 421 TRFAFKILSRVFNFDHVEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYA 480 Query: 477 EFIGKEIQTAYLESYSEYGQNVFDRYVTYADFWIQDQEFRDHDTGESFDRASLNAELEKI 536 EFIGKEIQTAYLESYSEYGQN+FDRYVTYADFWIQDQE+RD DTG+ FDR SLNAELEKI Sbjct: 481 EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKI 540 Query: 537 EKPAGRXPPE 546 EKPAG P+ Sbjct: 541 EKPAGISNPK 550 >ZyeaG [T] COG2766 Putative Ser protein kinase EcZ Escherichia coli O157:H7 EDL933 Length = 644 Score = 865 bits (2235), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/550 (73%), Positives = 476/550 (86%), Gaps = 4/550 (0%) Query: 1 MDIYSSFASRFDKTREEEFSLEEYLSLCKNDPAVYASAAERMLMAIGEPEKVDTREDPRL 60 M+I+ + R++ ++EEF+L+E+L+ C+ D + YA+AAER+LMAIGEP VDT ++PRL Sbjct: 1 MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAQEPRL 60 Query: 61 SRLFANKVIKVYPAFKEFYGAEEVIEQVVAYFRHASQGLEEKKQILYLLGPVGGGKSSIA 120 SRLF+N+VI YPAF+EFYG E+ IEQ+V+Y +HA+QGLEEKKQILYLLGPVGGGKSS+A Sbjct: 61 SRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLA 120 Query: 121 ERLKQLMEHIPFYSIKG----SPVNESPFGLFDYEEDGQILEEQFGIPRRYLKSILSPWA 176 ERLK LM+ +P Y + SPVN+ PF LF+ +ED QILE+++GIPRRYL +I+SPWA Sbjct: 121 ERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQILEKEYGIPRRYLGTIMSPWA 180 Query: 177 VKRLHEFNGDIRQFRVVKRYPSILRQIAISKTEPGDENNQDISTLVGKVDIRKLEQYSQD 236 KRLHEF GDI +FRVVK +PSIL+QIAI+KTEPGDENNQDIS LVGKVDIRKLE Y+Q+ Sbjct: 181 AKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDENNQDISALVGKVDIRKLEHYAQN 240 Query: 237 DADAYSYSGGLCLSNQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIIL 296 D DAY YSG LC +NQG++EFVEMFKAPIKVLHPLLTATQEGN+ GTEG A+PF+GIIL Sbjct: 241 DPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIIL 300 Query: 297 AHSNESEWKAFRNNKNNEALLDRIYIVKVPYCLRVSEEIRIYEKLLRTSSLANATCAPGT 356 AHSNESEW FRNNKNNEA LDR+YIVKVPYCLR+SEEI+IYEKLL S L +A CAPGT Sbjct: 301 AHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGT 360 Query: 357 LKMMAQFSILTRLGEPENSSLISKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGIS 416 L+ +++FSIL+RL EPENSS+ SKM+VYDGE+LKDTDPKAKSYQEYRDYAGVDEGM G+S Sbjct: 361 LETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLS 420 Query: 417 TRFAFKILSRVFNFDTTEIAANPVHLMYILEQQIEREQFPPEQEQKYLSFVKDTLASRYA 476 TRFAFKILSRVFNFD E+AANPVHL Y+LEQQIEREQFP EQ ++YL F+K L +YA Sbjct: 421 TRFAFKILSRVFNFDHVEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYA 480 Query: 477 EFIGKEIQTAYLESYSEYGQNVFDRYVTYADFWIQDQEFRDHDTGESFDRASLNAELEKI 536 EFIGKEIQTAYLESYSEYGQN+FDRYVTYADFWIQDQE+RD DTG+ FDR SLNAELEKI Sbjct: 481 EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKI 540 Query: 537 EKPAGRXPPE 546 EKPAG P+ Sbjct: 541 EKPAGISNPK 550 >ECs2492 [T] COG2766 Putative Ser protein kinase Ecs Escherichia coli O157:H7 Length = 644 Score = 865 bits (2235), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/550 (73%), Positives = 476/550 (86%), Gaps = 4/550 (0%) Query: 1 MDIYSSFASRFDKTREEEFSLEEYLSLCKNDPAVYASAAERMLMAIGEPEKVDTREDPRL 60 M+I+ + R++ ++EEF+L+E+L+ C+ D + YA+AAER+LMAIGEP VDT ++PRL Sbjct: 1 MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAQEPRL 60 Query: 61 SRLFANKVIKVYPAFKEFYGAEEVIEQVVAYFRHASQGLEEKKQILYLLGPVGGGKSSIA 120 SRLF+N+VI YPAF+EFYG E+ IEQ+V+Y +HA+QGLEEKKQILYLLGPVGGGKSS+A Sbjct: 61 SRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLA 120 Query: 121 ERLKQLMEHIPFYSIKG----SPVNESPFGLFDYEEDGQILEEQFGIPRRYLKSILSPWA 176 ERLK LM+ +P Y + SPVN+ PF LF+ +ED QILE+++GIPRRYL +I+SPWA Sbjct: 121 ERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQILEKEYGIPRRYLGTIMSPWA 180 Query: 177 VKRLHEFNGDIRQFRVVKRYPSILRQIAISKTEPGDENNQDISTLVGKVDIRKLEQYSQD 236 KRLHEF GDI +FRVVK +PSIL+QIAI+KTEPGDENNQDIS LVGKVDIRKLE Y+Q+ Sbjct: 181 AKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDENNQDISALVGKVDIRKLEHYAQN 240 Query: 237 DADAYSYSGGLCLSNQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIIL 296 D DAY YSG LC +NQG++EFVEMFKAPIKVLHPLLTATQEGN+ GTEG A+PF+GIIL Sbjct: 241 DPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIIL 300 Query: 297 AHSNESEWKAFRNNKNNEALLDRIYIVKVPYCLRVSEEIRIYEKLLRTSSLANATCAPGT 356 AHSNESEW FRNNKNNEA LDR+YIVKVPYCLR+SEEI+IYEKLL S L +A CAPGT Sbjct: 301 AHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGT 360 Query: 357 LKMMAQFSILTRLGEPENSSLISKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGIS 416 L+ +++FSIL+RL EPENSS+ SKM+VYDGE+LKDTDPKAKSYQEYRDYAGVDEGM G+S Sbjct: 361 LETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLS 420 Query: 417 TRFAFKILSRVFNFDTTEIAANPVHLMYILEQQIEREQFPPEQEQKYLSFVKDTLASRYA 476 TRFAFKILSRVFNFD E+AANPVHL Y+LEQQIEREQFP EQ ++YL F+K L +YA Sbjct: 421 TRFAFKILSRVFNFDHVEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYA 480 Query: 477 EFIGKEIQTAYLESYSEYGQNVFDRYVTYADFWIQDQEFRDHDTGESFDRASLNAELEKI 536 EFIGKEIQTAYLESYSEYGQN+FDRYVTYADFWIQDQE+RD DTG+ FDR SLNAELEKI Sbjct: 481 EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKI 540 Query: 537 EKPAGRXPPE 546 EKPAG P+ Sbjct: 541 EKPAGISNPK 550 >STM1285 [T] COG2766 Putative Ser protein kinase Sty Salmonella typhimurium LT2 Length = 644 Score = 864 bits (2233), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/550 (73%), Positives = 476/550 (86%), Gaps = 4/550 (0%) Query: 1 MDIYSSFASRFDKTREEEFSLEEYLSLCKNDPAVYASAAERMLMAIGEPEKVDTREDPRL 60 M+I+ + R++ ++EEF+L+++L++C+ D + YA+AAER+LMAIGEP VDT ++PRL Sbjct: 1 MNIFDHYRQRYEAAKDEEFTLQDFLTICRQDRSAYANAAERLLMAIGEPNMVDTAQEPRL 60 Query: 61 SRLFANKVIKVYPAFKEFYGAEEVIEQVVAYFRHASQGLEEKKQILYLLGPVGGGKSSIA 120 SRLF+N+VI YPAF+EFYG E+ IEQ+V+Y +HA+QGLEEKKQILYLLGPVGGGKSS+A Sbjct: 61 SRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLA 120 Query: 121 ERLKQLMEHIPFYSIKG----SPVNESPFGLFDYEEDGQILEEQFGIPRRYLKSILSPWA 176 ERLK LM+ +P Y + SPVN+ P LF+ +ED QILE+++GIPRRYL +I+SPWA Sbjct: 121 ERLKSLMQRVPIYVLSANGERSPVNDHPLCLFNPQEDAQILEKEYGIPRRYLGTIMSPWA 180 Query: 177 VKRLHEFNGDIRQFRVVKRYPSILRQIAISKTEPGDENNQDISTLVGKVDIRKLEQYSQD 236 KRLHEF GDI +FRVVK +PSIL QIAI+KTEPGDENNQDIS LVGKVDIRKLE ++Q+ Sbjct: 181 AKRLHEFGGDITKFRVVKVWPSILEQIAIAKTEPGDENNQDISALVGKVDIRKLEHHAQN 240 Query: 237 DADAYSYSGGLCLSNQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIIL 296 D DAY YSG LC +NQG++EFVEMFKAPIKVLHPLLTATQEGN+ GTEG A+PF+GIIL Sbjct: 241 DPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIIL 300 Query: 297 AHSNESEWKAFRNNKNNEALLDRIYIVKVPYCLRVSEEIRIYEKLLRTSSLANATCAPGT 356 AHSNESEW FRNNKNNEA LDR+YIVKVPYCLR+SEEI+IYEKLL S LA+A CAPGT Sbjct: 301 AHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELAHAPCAPGT 360 Query: 357 LKMMAQFSILTRLGEPENSSLISKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGIS 416 L+ +++FSIL+RL EPENSS+ SKM+VYDGE+LKDTDPKAKSYQEYRDYAGVDEGM G+S Sbjct: 361 LETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLS 420 Query: 417 TRFAFKILSRVFNFDTTEIAANPVHLMYILEQQIEREQFPPEQEQKYLSFVKDTLASRYA 476 TRFAFKILSRVFNFD E+AANPVHL Y+LEQQIEREQFP EQ ++YL F+K L +YA Sbjct: 421 TRFAFKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYA 480 Query: 477 EFIGKEIQTAYLESYSEYGQNVFDRYVTYADFWIQDQEFRDHDTGESFDRASLNAELEKI 536 EFIGKEIQTAYLESYSEYGQN+FDRYVTYADFWIQDQE+RD DTG+ FDR SLNAELEKI Sbjct: 481 EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKI 540 Query: 537 EKPAGRXPPE 546 EKPAG P+ Sbjct: 541 EKPAGISNPK 550 >PA0588 [T] COG2766 Putative Ser protein kinase Pae Pseudomonas aeruginosa Length = 640 Score = 863 bits (2230), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/546 (76%), Positives = 481/546 (88%) Query: 1 MDIYSSFASRFDKTREEEFSLEEYLSLCKNDPAVYASAAERMLMAIGEPEKVDTREDPRL 60 M I+S F RF+ TR+EE+SL+EYL LCK D YASAAER+LMAIGEPE +DT D RL Sbjct: 1 MSIFSHFQERFEATRQEEYSLQEYLDLCKQDKTAYASAAERLLMAIGEPELLDTSVDSRL 60 Query: 61 SRLFANKVIKVYPAFKEFYGAEEVIEQVVAYFRHASQGLEEKKQILYLLGPVGGGKSSIA 120 SR+F+NKVI+ YPAF +F+G EE I+Q+VA+FRHA+QGLEEKKQILYLLGPVGGGKSS+A Sbjct: 61 SRIFSNKVIRRYPAFADFHGMEECIDQIVAFFRHAAQGLEEKKQILYLLGPVGGGKSSLA 120 Query: 121 ERLKQLMEHIPFYSIKGSPVNESPFGLFDYEEDGQILEEQFGIPRRYLKSILSPWAVKRL 180 E+LKQLME +PFY+IKGSPV ESP GLF+ +EDG ILEE +GIPRRYL+SI+SPWA KRL Sbjct: 121 EKLKQLMEKVPFYAIKGSPVFESPLGLFNPDEDGAILEEDYGIPRRYLRSIMSPWATKRL 180 Query: 181 HEFNGDIRQFRVVKRYPSILRQIAISKTEPGDENNQDISTLVGKVDIRKLEQYSQDDADA 240 +EF GDI QFRVVK YPSIL QIAI+KTEPGDENNQDIS LVGKVDIRKLE+Y Q+DADA Sbjct: 181 NEFGGDISQFRVVKLYPSILNQIAIAKTEPGDENNQDISALVGKVDIRKLEEYPQNDADA 240 Query: 241 YSYSGGLCLSNQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIILAHSN 300 YSYSG LC +NQGL+EFVEMFKAPIKVLHPLLTATQEGN+ TEG GA+P+ GIILAHSN Sbjct: 241 YSYSGALCRANQGLMEFVEMFKAPIKVLHPLLTATQEGNYNSTEGLGALPYSGIILAHSN 300 Query: 301 ESEWKAFRNNKNNEALLDRIYIVKVPYCLRVSEEIRIYEKLLRTSSLANATCAPGTLKMM 360 ESEW +FRNNKNNEA +DRIYIVKVPYCLRV++EI+IY+KLL SSLA+A CAP TLKM+ Sbjct: 301 ESEWHSFRNNKNNEAFIDRIYIVKVPYCLRVADEIKIYDKLLVNSSLAHAHCAPDTLKML 360 Query: 361 AQFSILTRLGEPENSSLISKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGISTRFA 420 +QFS+L+RL EPENS++ SKM+VYDGENLKDTDPKAKS QEYRD AGVDEGM G+STRFA Sbjct: 361 SQFSVLSRLKEPENSNIYSKMRVYDGENLKDTDPKAKSIQEYRDSAGVDEGMAGLSTRFA 420 Query: 421 FKILSRVFNFDTTEIAANPVHLMYILEQQIEREQFPPEQEQKYLSFVKDTLASRYAEFIG 480 FKILS+VFNFD E+AANPVHL+Y+LEQQIE+EQF PE ++YL F+K+ LA RY EFIG Sbjct: 421 FKILSKVFNFDPHEVAANPVHLLYVLEQQIEQEQFQPETRERYLRFIKEYLAPRYVEFIG 480 Query: 481 KEIQTAYLESYSEYGQNVFDRYVTYADFWIQDQEFRDHDTGESFDRASLNAELEKIEKPA 540 KEIQTAYLESYSEYGQN+FDRYV YADFWIQDQE+RD +TGE +RA+LN ELEKIEKPA Sbjct: 481 KEIQTAYLESYSEYGQNIFDRYVLYADFWIQDQEYRDPETGEILNRAALNEELEKIEKPA 540 Query: 541 GRXPPE 546 G P+ Sbjct: 541 GISNPK 546