BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0719.p (303 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 304 1e-82 YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 294 2e-79 yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 281 1e-75 ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 281 1e-75 ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 281 1e-75 >PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 304 bits (779), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 154/292 (52%), Positives = 202/292 (69%), Gaps = 1/292 (0%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELENTLAVQLFDRVGKRLMLN 60 M ++ RQLQIF AVA+ GSTTAAA+ ++LSQSA SAALNELE+ L+ +LFDRVGKRL LN Sbjct: 1 MALSFRQLQIFCAVARCGSTTAAAESISLSQSATSAALNELESQLSTRLFDRVGKRLQLN 60 Query: 61 DNGRLLLPQAQHLLDAANTIEQQFLTPDQVGAELHIGASTTIGSYMLPQMVAAYRRDHPQ 120 + GR LPQA LLD +EQQF A L + AS+TIG+Y+LP+++A++ R+ P Sbjct: 61 EVGRRFLPQALRLLDGVAQLEQQFAVSAAPQASLTVAASSTIGNYVLPRLLASFEREQPG 120 Query: 121 LRVRALVANTADIVNAVSNFEVDAALIEGPCHASDVDVEPWMTDELIVVASPQHALAAQG 180 +RV A + NT V V F D LIEGPCH + VEPW+ D LIVVA+P H LA++ Sbjct: 121 VRVNASIGNTGSAVQDVVTFAADIGLIEGPCHEPGLRVEPWLEDSLIVVAAPGHPLASR- 179 Query: 181 KKLTLKTLSEADWLLREAGSGTREAVEHALLPYLHHLPSACEFGNSEAIKRATAEGMGIS 240 +++ + L A WLLRE GSGTRE V HALL +LH+L + + G+SEAIK + A G+GIS Sbjct: 180 TQVSREALRRARWLLREPGSGTREEVSHALLGHLHYLEDSLDLGSSEAIKHSVAAGLGIS 239 Query: 241 CLSRAVVVDLLESGRLIELATPLPPLRRHFYLVRNKHRVLSVRLASLLDFCR 292 CLSR VV + L +G L+EL + LPPLRR FY++R + + LS + CR Sbjct: 240 CLSRWVVEEQLATGALVELRSSLPPLRRRFYMLRQRDKFLSPGFERFWEHCR 291 >YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 290 Score = 294 bits (752), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 156/293 (53%), Positives = 200/293 (68%), Gaps = 5/293 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELENTLAVQLFDRVGKRLMLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE L VQLFDRVGKRL+ N Sbjct: 1 MHITLRQLEVFTEVLKSGSTTQASVVLALSQSAVSAALADLEGQLGVQLFDRVGKRLVTN 60 Query: 61 DNGRLLLPQAQHLLDAANTIEQQFLTPDQVGAELHIGASTTIGSYMLPQMVAAYRRDHPQ 120 ++GRLL P+A LLD A IEQ FL +GA L I AS+TIG+YMLP M+A YRRD P Sbjct: 61 EHGRLLYPKALALLDQAIEIEQLFL--HDLGA-LRIAASSTIGNYMLPGMIAKYRRDFPG 117 Query: 121 LRVRALVANTADIVNAVSNFEVDAALIEGPCHASDVDVEPWMTDELIVVASPQHALAAQG 180 + + N+ D++ AV++F D LIEGPCH ++ + W+ DEL+V A+P L Sbjct: 118 TPLELNIGNSQDVIEAVADFRGDLGLIEGPCHMPELVTQNWLRDELVVFAAPDSPLCH-- 175 Query: 181 KKLTLKTLSEADWLLREAGSGTREAVEHALLPYLHHLPSACEFGNSEAIKRATAEGMGIS 240 K LTL L++ADW+LRE GSGTRE ++H LL L H E GNSEAIKRA GMG+S Sbjct: 176 KALTLVDLADADWILRERGSGTREVLDHLLLAQLPHFKLVMELGNSEAIKRAVRYGMGVS 235 Query: 241 CLSRAVVVDLLESGRLIELATPLPPLRRHFYLVRNKHRVLSVRLASLLDFCRD 293 CLSR V+ D L SG L+EL PLPPL R YL+ ++ + +S L L +C++ Sbjct: 236 CLSRRVIADQLASGELVELNIPLPPLIRTLYLIHHRQKHISNALLRFLSYCQE 288 >yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 293 Score = 281 bits (719), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 150/291 (51%), Positives = 201/291 (69%), Gaps = 5/291 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELENTLAVQLFDRVGKRLMLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE L VQLFDRVGKRL++N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DNGRLLLPQAQHLLDAANTIEQQFLTPDQVGAELHIGASTTIGSYMLPQMVAAYRRDHPQ 120 ++GRLL P+A LL+ A IEQ F + GA + I AS+TIG+Y+LP ++A YR D+PQ Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDN--GA-IRIYASSTIGNYILPAVIARYRHDYPQ 117 Query: 121 LRVRALVANTADIVNAVSNFEVDAALIEGPCHASDVDVEPWMTDELIVVASPQHALAAQG 180 L + V N+ D++ AV +F VD IEGPCH++++ EPW+ DEL+V A+P LA Sbjct: 118 LPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLAR-- 175 Query: 181 KKLTLKTLSEADWLLREAGSGTREAVEHALLPYLHHLPSACEFGNSEAIKRATAEGMGIS 240 +TL+ L+ A W+LRE GSGTRE V++ LL +L A E GNSEAIK A G+GIS Sbjct: 176 GPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGIS 235 Query: 241 CLSRAVVVDLLESGRLIELATPLPPLRRHFYLVRNKHRVLSVRLASLLDFC 291 CLSR V+ D L++G L E+A PLP L R + + ++ + LS L LD+C Sbjct: 236 CLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 281 bits (719), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 150/291 (51%), Positives = 201/291 (69%), Gaps = 5/291 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELENTLAVQLFDRVGKRLMLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE L VQLFDRVGKRL++N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DNGRLLLPQAQHLLDAANTIEQQFLTPDQVGAELHIGASTTIGSYMLPQMVAAYRRDHPQ 120 ++GRLL P+A LL+ A IEQ F + GA + I AS+TIG+Y+LP ++A YR D+PQ Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDN--GA-IRIYASSTIGNYILPAVIARYRHDYPQ 117 Query: 121 LRVRALVANTADIVNAVSNFEVDAALIEGPCHASDVDVEPWMTDELIVVASPQHALAAQG 180 L + V N+ D++ AV +F VD IEGPCH++++ EPW+ DEL+V A+P LA Sbjct: 118 LPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLAR-- 175 Query: 181 KKLTLKTLSEADWLLREAGSGTREAVEHALLPYLHHLPSACEFGNSEAIKRATAEGMGIS 240 +TL+ L+ A W+LRE GSGTRE V++ LL +L A E GNSEAIK A G+GIS Sbjct: 176 GPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGIS 235 Query: 241 CLSRAVVVDLLESGRLIELATPLPPLRRHFYLVRNKHRVLSVRLASLLDFC 291 CLSR V+ D L++G L E+A PLP L R + + ++ + LS L LD+C Sbjct: 236 CLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 293 Score = 281 bits (719), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 150/291 (51%), Positives = 201/291 (69%), Gaps = 5/291 (1%) Query: 1 MKITLRQLQIFLAVAQSGSTTAAADLVALSQSAASAALNELENTLAVQLFDRVGKRLMLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE L VQLFDRVGKRL++N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DNGRLLLPQAQHLLDAANTIEQQFLTPDQVGAELHIGASTTIGSYMLPQMVAAYRRDHPQ 120 ++GRLL P+A LL+ A IEQ F + GA + I AS+TIG+Y+LP ++A YR D+PQ Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDN--GA-IRIYASSTIGNYILPAVIARYRHDYPQ 117 Query: 121 LRVRALVANTADIVNAVSNFEVDAALIEGPCHASDVDVEPWMTDELIVVASPQHALAAQG 180 L + V N+ D++ AV +F VD IEGPCH++++ EPW+ DEL+V A+P LA Sbjct: 118 LPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPLAR-- 175 Query: 181 KKLTLKTLSEADWLLREAGSGTREAVEHALLPYLHHLPSACEFGNSEAIKRATAEGMGIS 240 +TL+ L+ A W+LRE GSGTRE V++ LL +L A E GNSEAIK A G+GIS Sbjct: 176 GPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGIS 235 Query: 241 CLSRAVVVDLLESGRLIELATPLPPLRRHFYLVRNKHRVLSVRLASLLDFC 291 CLSR V+ D L++G L E+A PLP L R + + ++ + LS L LD+C Sbjct: 236 CLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286