BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0683.p (469 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0093 [H] COG0499 S-adenosylhomocysteine hydrolase Rso Ralston... 780 0.0 BMEI2029 [H] COG0499 S-adenosylhomocysteine hydrolase Bme Brucel... 641 0.0 mll5088 [H] COG0499 S-adenosylhomocysteine hydrolase Mlo Mesorhi... 634 0.0 CC0257 Non COG 634 0.0 SMc02755 [H] COG0499 S-adenosylhomocysteine hydrolase Sme Sinorh... 626 e-179 >RSc0093 [H] COG0499 S-adenosylhomocysteine hydrolase Rso Ralstonia solanacearum Length = 474 Score = 780 bits (2015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/472 (80%), Positives = 415/472 (87%), Gaps = 13/472 (2%) Query: 9 TNSTKDYVIADISLAQWGHKEIKIAETEMPGLMAIREEFAAAQPLKGARITGSIHMTIQT 68 T+ DY++ADI LA WG KEI IAETEMPGLMAIR+EFAA+QPLKGARI GS+HMTIQT Sbjct: 5 TDLKHDYLVADIKLADWGRKEIAIAETEMPGLMAIRDEFAASQPLKGARIAGSLHMTIQT 64 Query: 69 AVLIQTLEALGAKVRWASCNIYSTQDHAAAAIADKGTPVFAFKGESLDDYWEFTHRIFEW 128 AVLI+TL+ALGA VRWASCNI+STQDHAAAAIA GTPVFAFKGESL +YW+FTHRIFEW Sbjct: 65 AVLIETLKALGADVRWASCNIFSTQDHAAAAIAASGTPVFAFKGESLKEYWDFTHRIFEW 124 Query: 129 QGGENEQANMILDDGGDATLLLHLGTRAEKDASVLNNPGSEEEICLFNSIKKX------- 181 G NMILDDGGDATLLLHLG +AE+DASV+ PGSEEE LF +IK+ Sbjct: 125 ADGGT--PNMILDDGGDATLLLHLGAKAEQDASVIAKPGSEEETFLFAAIKEKLAKDATF 182 Query: 182 YSTRLAQVKGVTEETTTGVHRLYQMFKDGKLAFPAINVNDSVTKSKFDNLYGCRESLVDG 241 YS L +KGVTEETTTGVHRLYQM + G+L FPAINVNDSVTKSKFDNLYGCRESLVDG Sbjct: 183 YSRNLDAIKGVTEETTTGVHRLYQMAQRGELRFPAINVNDSVTKSKFDNLYGCRESLVDG 242 Query: 242 IKRATDVMIAGKVAVIAGYGDVGKGSAQAMRALSAQVWVTEIDPICALQAAMEGYRVVTM 301 IKRATDVMIAGKVAV+AGYGDVGKGSAQA+RALSAQVWVTEIDPICALQAAMEGYRVVTM Sbjct: 243 IKRATDVMIAGKVAVVAGYGDVGKGSAQALRALSAQVWVTEIDPICALQAAMEGYRVVTM 302 Query: 302 DYAAEHGDIFVTCTGNYHVITHDHMKKMKDQAIVCNIGHFDNEIEVAALKQYSWENIKPQ 361 DYAAEHGDIFVTCTGNYHVITHDHM KMKDQAIVCNIGHFDNEI++A+++QY WE IKPQ Sbjct: 303 DYAAEHGDIFVTCTGNYHVITHDHMAKMKDQAIVCNIGHFDNEIDIASVEQYQWEEIKPQ 362 Query: 362 VDHVIFPDGKRIILLAEGRLVNLGCGTGHPSYVMSSSFANQTIAQIELFVN----TKNYP 417 VDHVIFPDGK+II+LA+GRLVNLGC TGHPSYVMSSSFANQTIAQIEL+ + YP Sbjct: 363 VDHVIFPDGKKIIILAKGRLVNLGCATGHPSYVMSSSFANQTIAQIELWTEAQKGSSKYP 422 Query: 418 VGVYTLPKHLDEKVARLQLKKLNAQLSTLTAEQASYIGVKSDGPYKPDHYRY 469 VGVYTLPKHLDEKVARLQLKKLNAQL+ LT +QA+YIGV +GPYK DHYRY Sbjct: 423 VGVYTLPKHLDEKVARLQLKKLNAQLTVLTDKQAAYIGVSKEGPYKADHYRY 474 >BMEI2029 [H] COG0499 S-adenosylhomocysteine hydrolase Bme Brucella melitensis Length = 481 Score = 641 bits (1654), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/471 (67%), Positives = 375/471 (79%), Gaps = 11/471 (2%) Query: 6 AMTTNSTKDYVIADISLAQWGHKEIKIAETEMPGLMAIREEFAAAQPLKGARITGSIHMT 65 AMT +++D+V+ DISLA WG +E+ IAETEMPGLMA REEF +QPLKGARI+GS+HMT Sbjct: 15 AMT--ASQDFVVKDISLADWGRRELDIAETEMPGLMAAREEFGKSQPLKGARISGSLHMT 72 Query: 66 IQTAVLIQTLEALGAKVRWASCNIYSTQDHAAAAIADKGTPVFAFKGESLDDYWEFTHRI 125 IQTAVLI+TL+ LGA+VRWASCNI+STQDHAAAAIA GTPVFA KGE+L++YW +T +I Sbjct: 73 IQTAVLIETLKVLGAEVRWASCNIFSTQDHAAAAIAATGTPVFAVKGETLEEYWTYTDQI 132 Query: 126 FEWQGGENEQANMILDDGGDATLLLHLGTRAEKDASVLNNPGSEEEICLFNSIKKX---- 181 F+W GE +NMILDDGGDAT+ + +G RAE VL+NP SEEE LF IKK Sbjct: 133 FQWPDGE--PSNMILDDGGDATMYILIGARAEAGEDVLSNPQSEEEEVLFAQIKKRMAAT 190 Query: 182 ---YSTRLAQVKGVTEETTTGVHRLYQMFKDGKLAFPAINVNDSVTKSKFDNLYGCRESL 238 ++ + A +KGVTEETTTGV+RLYQ+ K G L FPAINVNDSVTKSKFDN YGC+ESL Sbjct: 191 PGFFTKQRAAIKGVTEETTTGVNRLYQLQKKGLLPFPAINVNDSVTKSKFDNKYGCKESL 250 Query: 239 VDGIKRATDVMIAGKVAVIAGYGDVGKGSAQAMRALSAQVWVTEIDPICALQAAMEGYRV 298 VDGI+R TDVM+AGKVAV+ GYGDVGKGSAQ++ A+V VTE+DPICALQAAM+G+ V Sbjct: 251 VDGIRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEV 310 Query: 299 VTMDYAAEHGDIFVTCTGNYHVITHDHMKKMKDQAIVCNIGHFDNEIEVAALKQYSWENI 358 VT+D AA DI VT TGN VIT DHM+KMKD IV NIGHFDNEI+VAAL+ W N+ Sbjct: 311 VTLDDAASTADIVVTTTGNKDVITIDHMRKMKDMCIVGNIGHFDNEIQVAALRNLKWTNV 370 Query: 359 KPQVDHVIFPDGKRIILLAEGRLVNLGCGTGHPSYVMSSSFANQTIAQIELFVNTKNYPV 418 KPQVD + FPDGKR+ILL+EGRL+NLG TGHPS+VMS+SF NQ + QIELF T Y Sbjct: 371 KPQVDLIEFPDGKRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLGQIELFTRTDAYKN 430 Query: 419 GVYTLPKHLDEKVARLQLKKLNAQLSTLTAEQASYIGVKSDGPYKPDHYRY 469 VY LPKHLDEKVARL L KL A+L+ L+ EQA+YIGV GP+K +HYRY Sbjct: 431 EVYVLPKHLDEKVARLHLDKLGAKLTVLSEEQAAYIGVTPQGPFKSEHYRY 481 >mll5088 [H] COG0499 S-adenosylhomocysteine hydrolase Mlo Mesorhizobium loti Length = 466 Score = 634 bits (1636), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/465 (66%), Positives = 370/465 (79%), Gaps = 9/465 (1%) Query: 12 TKDYVIADISLAQWGHKEIKIAETEMPGLMAIREEFAAAQPLKGARITGSIHMTIQTAVL 71 +KDYV+ADISLA WG KE+ IAETEMPGLMA REEF A +PLKGARITGS+HMTIQTAVL Sbjct: 4 SKDYVVADISLAGWGRKELDIAETEMPGLMACREEFGAKKPLKGARITGSLHMTIQTAVL 63 Query: 72 IQTLEALGAKVRWASCNIYSTQDHAAAAIADKGTPVFAFKGESLDDYWEFTHRIFEWQGG 131 I+TL+ALGA +RWASCNI+STQDHAAAAIA+ G PVFA KGESL+ YW++T RIF+W G Sbjct: 64 IETLKALGADIRWASCNIFSTQDHAAAAIAEAGIPVFAVKGESLEQYWDYTDRIFQWADG 123 Query: 132 ENEQANMILDDGGDATLLLHLGTRAEKDASVLNNPGSEEEICLFNSIKKX-------YST 184 +NMILDDGGDAT+ + +G RAE VL+NP SEEE + +KK ++ Sbjct: 124 G--LSNMILDDGGDATMYILIGARAEAGEDVLSNPQSEEEEYFYAQVKKRLKASPGFFTK 181 Query: 185 RLAQVKGVTEETTTGVHRLYQMFKDGKLAFPAINVNDSVTKSKFDNLYGCRESLVDGIKR 244 + A ++GVTEETTTGV+RLYQ+ K G L FPAINVNDSVTKSKFDN YGC+ESLVDGI+R Sbjct: 182 QKAAIRGVTEETTTGVNRLYQLQKKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRR 241 Query: 245 ATDVMIAGKVAVIAGYGDVGKGSAQAMRALSAQVWVTEIDPICALQAAMEGYRVVTMDYA 304 TD M+AGKVAV+ GYGDVGKGS+ +++ A+V VTE+DPICALQAAM+G+ VVT++ A Sbjct: 242 GTDTMMAGKVAVVCGYGDVGKGSSASLKGAGARVKVTEVDPICALQAAMDGFEVVTLEDA 301 Query: 305 AEHGDIFVTCTGNYHVITHDHMKKMKDQAIVCNIGHFDNEIEVAALKQYSWENIKPQVDH 364 A DI +T TGN V+T DHM+ MKD IV NIGHFDNEI+VA+L+ W N+KPQVD Sbjct: 302 APTADIVITTTGNKDVVTLDHMRSMKDMVIVGNIGHFDNEIQVASLRNLKWTNVKPQVDM 361 Query: 365 VIFPDGKRIILLAEGRLVNLGCGTGHPSYVMSSSFANQTIAQIELFVNTKNYPVGVYTLP 424 + FPDGKR+ILL+EGRL+NLG TGHPS+VMS+SF NQ +AQIELF + Y VY LP Sbjct: 362 ITFPDGKRMILLSEGRLLNLGNATGHPSFVMSASFTNQVLAQIELFTKGEQYQNQVYVLP 421 Query: 425 KHLDEKVARLQLKKLNAQLSTLTAEQASYIGVKSDGPYKPDHYRY 469 KHLDEKVARL L KL A+L+ L+ EQA+YIGV GP+KP+HYRY Sbjct: 422 KHLDEKVARLHLDKLGARLTELSGEQAAYIGVTPQGPFKPEHYRY 466 >CC0257 Non COG Length = 463 Score = 634 bits (1635), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/463 (67%), Positives = 368/463 (79%), Gaps = 9/463 (1%) Query: 14 DYVIADISLAQWGHKEIKIAETEMPGLMAIREEFAAAQPLKGARITGSIHMTIQTAVLIQ 73 DY++ DISLA +G KEI IAETEMPGLMA R E+ Q LKGARI GS+HMTIQTAVLI+ Sbjct: 3 DYIVKDISLADFGRKEIAIAETEMPGLMATRAEYGPQQILKGARIAGSLHMTIQTAVLIE 62 Query: 74 TLEALGAKVRWASCNIYSTQDHAAAAIADKGTPVFAFKGESLDDYWEFTHRIFEWQGGEN 133 TL ALGA+VRWASCNI+STQDHAAAAIA G PVFAFKGE+L +YWE+ H+IFEW G Sbjct: 63 TLTALGAEVRWASCNIFSTQDHAAAAIAAAGVPVFAFKGENLVEYWEYAHKIFEWHDGG- 121 Query: 134 EQANMILDDGGDATLLLHLGTRAEKDASVLNNPGSEEEICLFNSIKK-------XYSTRL 186 N+ILDDGGDATLL LG +AEKD S+LNNP +EEE L+ +KK YS Sbjct: 122 -YPNLILDDGGDATLLCVLGPKAEKDPSILNNPQNEEEEALYAVMKKYLAEKPGFYSAIR 180 Query: 187 AQVKGVTEETTTGVHRLYQMFKDGKLAFPAINVNDSVTKSKFDNLYGCRESLVDGIKRAT 246 A + GV+EETTTGVHRLYQM + +L FPAINVNDSVTKSKFDNLYGCRESLVD I+R T Sbjct: 181 AAIGGVSEETTTGVHRLYQMAQKDELPFPAINVNDSVTKSKFDNLYGCRESLVDAIRRGT 240 Query: 247 DVMIAGKVAVIAGYGDVGKGSAQAMRALSAQVWVTEIDPICALQAAMEGYRVVTMDYAAE 306 DVM++GKVAV+ GYGDVGKGSA ++R A+V VTE+DPICALQAAMEGY V T++ A+ Sbjct: 241 DVMLSGKVAVVCGYGDVGKGSAASLRQGGARVIVTEVDPICALQAAMEGYEVQTLNDVAD 300 Query: 307 HGDIFVTCTGNYHVITHDHMKKMKDQAIVCNIGHFDNEIEVAALKQYSWENIKPQVDHVI 366 DIFVT TGN VIT D M+KMK+ AIVCNIGHFD+EI++A L+ + W+ IKPQV HV Sbjct: 301 KADIFVTATGNKDVITVDDMRKMKNNAIVCNIGHFDSEIQIAGLRNFKWDEIKPQVHHVE 360 Query: 367 FPDGKRIILLAEGRLVNLGCGTGHPSYVMSSSFANQTIAQIELFVNTKNYPVGVYTLPKH 426 FPDGK++I+L+EGRLVNLG TGHPS+VMS+SF NQT+AQIEL+ N Y VYTLPKH Sbjct: 361 FPDGKKLIVLSEGRLVNLGNATGHPSFVMSASFTNQTLAQIELWTNKAKYENQVYTLPKH 420 Query: 427 LDEKVARLQLKKLNAQLSTLTAEQASYIGVKSDGPYKPDHYRY 469 LDEKVA L L+KL A+L+TL +QA YIGV GP+KPDHYRY Sbjct: 421 LDEKVAFLHLEKLGAKLTTLRKDQADYIGVPEAGPFKPDHYRY 463 >SMc02755 [H] COG0499 S-adenosylhomocysteine hydrolase Sme Sinorhizobium meliloti Length = 466 Score = 626 bits (1614), Expect = e-179, Method: Compositional matrix adjust. Identities = 307/467 (65%), Positives = 367/467 (78%), Gaps = 9/467 (1%) Query: 10 NSTKDYVIADISLAQWGHKEIKIAETEMPGLMAIREEFAAAQPLKGARITGSIHMTIQTA 69 ++T+DY++ADI LA +G KEI IAETEMPGLMA REEF A++PLKGARITGS+HMTIQTA Sbjct: 2 SATQDYIVADIGLADFGRKEIAIAETEMPGLMACREEFGASKPLKGARITGSLHMTIQTA 61 Query: 70 VLIQTLEALGAKVRWASCNIYSTQDHAAAAIADKGTPVFAFKGESLDDYWEFTHRIFEWQ 129 VLI+TL ALGA+VRWASCNI+STQDHAAAAIA G PVFA KGE+L++YW +T +IF+W Sbjct: 62 VLIETLVALGAEVRWASCNIFSTQDHAAAAIAASGVPVFAVKGETLEEYWTYTDKIFQWA 121 Query: 130 GGENEQANMILDDGGDATLLLHLGTRAEKDASVLNNPGSEEEICLFNSIKKX-------Y 182 G +NMILDDGGDAT+ + LG RAE ++L NPGSEEE LF IKK + Sbjct: 122 DGG--VSNMILDDGGDATMYILLGARAEAGENILTNPGSEEEEILFAQIKKRLAATPGWF 179 Query: 183 STRLAQVKGVTEETTTGVHRLYQMFKDGKLAFPAINVNDSVTKSKFDNLYGCRESLVDGI 242 + + +KGVTEETTTGV+RLYQ+ G L FPAINVNDSVTKSKFDN YGC+ESLVDGI Sbjct: 180 TRQRDAIKGVTEETTTGVNRLYQLQAKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGI 239 Query: 243 KRATDVMIAGKVAVIAGYGDVGKGSAQAMRALSAQVWVTEIDPICALQAAMEGYRVVTMD 302 +R TDVM+AGKVAV+ GYGDVGKGSA ++ A+V VTE+DPICALQAAM+GY VV ++ Sbjct: 240 RRGTDVMMAGKVAVVCGYGDVGKGSAASLSGAGARVKVTEVDPICALQAAMDGYEVVQLE 299 Query: 303 YAAEHGDIFVTCTGNYHVITHDHMKKMKDQAIVCNIGHFDNEIEVAALKQYSWENIKPQV 362 DIF+T TGN VI +HM+ MKD AIV NIGHFDNEI+V+AL+ W N+KPQV Sbjct: 300 DVVSSADIFITTTGNKDVIRIEHMRAMKDMAIVGNIGHFDNEIQVSALRNLKWTNVKPQV 359 Query: 363 DHVIFPDGKRIILLAEGRLVNLGCGTGHPSYVMSSSFANQTIAQIELFVNTKNYPVGVYT 422 D + FP G RIILL+EGRL+NLG TGHPS+VMS+SF+NQ +AQIELF + Y VY Sbjct: 360 DLIEFPKGNRIILLSEGRLLNLGNATGHPSFVMSASFSNQVLAQIELFTKGEQYKNEVYV 419 Query: 423 LPKHLDEKVARLQLKKLNAQLSTLTAEQASYIGVKSDGPYKPDHYRY 469 LPK LDEKVARL L KL A+L+ L+ EQASYIGVK GP+K +HYRY Sbjct: 420 LPKQLDEKVARLHLAKLGAKLTELSEEQASYIGVKQQGPFKAEHYRY 466