BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0616.p (188 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value HI0694 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 203 2e-52 L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 201 5e-52 ymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase a... 198 5e-51 NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 198 5e-51 ECs1607 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 197 9e-51 >HI0694 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Hin Haemophilus influenzae Length = 240 Score = 203 bits (516), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 98/181 (54%), Positives = 133/181 (73%), Gaps = 3/181 (1%) Query: 3 LILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAISH 62 ++LFNKP+ V+ QF+ + R TL D++ IP++Y AGRLD DSEGL++LT++GELQH ++ Sbjct: 53 VVLFNKPFDVLTQFTDEQGRATLKDFISIPNVYAAGRLDRDSEGLLILTNNGELQHRLAD 112 Query: 63 PKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIRER 122 PK K K Y VQVEG P+ L +LR ++L D VT+ ++VR + EP LW RNPPIRER Sbjct: 113 PKFKTEKTYWVQVEGIPEETDLAQLRKGVELKDGVTKSAKVRLISEPN-LWERNPPIRER 171 Query: 123 KNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTVDPQ 182 KN PTSWL I+ISEG+NRQVRRMTA +G PTLRLVR+++G L+ + L G ++ + Sbjct: 172 KNIPTSWLEIKISEGRNRQVRRMTAHIGFPTLRLVRVSMG--LLSINGLENGSFRLLSLD 229 Query: 183 E 183 E Sbjct: 230 E 230 >L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Lla Lactococcus lactis Length = 185 Score = 201 bits (512), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 98/177 (55%), Positives = 127/177 (71%), Gaps = 2/177 (1%) Query: 3 LILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAISH 62 +ILFNKPY V+ +F+ + R+TL DY+ IP++Y AGRLD DSEGL+LLTDDG+L H ++ Sbjct: 9 IILFNKPYDVLTKFTDGEGRKTLKDYIKIPNVYAAGRLDKDSEGLLLLTDDGKLNHLLTD 68 Query: 63 PKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIRER 122 PK K K YLVQVEG + ++L+ L L D T ++V+ + EP WLW R PPIRER Sbjct: 69 PKSKSYKTYLVQVEGEFSPEAAQKLQKGLLLKDGKTLPAKVKLIDEPDWLWERTPPIRER 128 Query: 123 KNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTV 179 K PTSW+ I I EGKNRQ+RRMTAAVG PTLRL+R +IG ++L L GE+K + Sbjct: 129 KAIPTSWVEISIKEGKNRQIRRMTAAVGFPTLRLIRWSIGQYSLGN--LKSGEYKII 183 >ymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Eco Escherichia coli K12 Length = 207 Score = 198 bits (504), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 97/177 (54%), Positives = 128/177 (72%), Gaps = 2/177 (1%) Query: 3 LILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAISH 62 +ILFNKPY V+ QF+ + R+TL +++ + +Y AGRLD DSEGL++LT++G LQ ++ Sbjct: 31 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 90 Query: 63 PKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIRER 122 P ++ K+Y VQVEG P ++LE LRN + L D T + V EPAWLWPRNPPIRER Sbjct: 91 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 150 Query: 123 KNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWKTV 179 K+ PTSWL I + EG+NRQVRRMTA VG PTLRL+R A+G ++L D L GEW+ V Sbjct: 151 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSL--DNLANGEWREV 205 >NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Nme Neisseria meningitidis MC58 Length = 186 Score = 198 bits (504), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 100/176 (56%), Positives = 120/176 (68%), Gaps = 2/176 (1%) Query: 3 LILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAISH 62 LI FNKPY V+CQFS + ++L D++++P YPAGRLD DSEGL+LLTDDG LQ I+ Sbjct: 4 LIAFNKPYGVICQFSPHEKHKSLKDFINLPGFYPAGRLDTDSEGLLLLTDDGRLQAQITD 63 Query: 63 PKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQ--EPAWLWPRNPPIR 120 PK K PK Y Q+EG PD + LE LR +DLG FVTR + +R ++ E LW R PPIR Sbjct: 64 PKFKHPKTYWAQLEGVPDESRLESLRKGIDLGGFVTRPASIRILKHGEADSLWERIPPIR 123 Query: 121 ERKNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEW 176 RK P W+ I ISEGKNRQVRRMTA G P LRL+R+A G L L PGEW Sbjct: 124 VRKTVPDFWIEITISEGKNRQVRRMTAKAGYPCLRLIRVASGRLKLFDLDLKPGEW 179 >ECs1607 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Ecs Escherichia coli O157:H7 Length = 217 Score = 197 bits (502), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 96/175 (54%), Positives = 127/175 (72%), Gaps = 2/175 (1%) Query: 3 LILFNKPYQVMCQFSAQDDRETLADYLDIPDIYPAGRLDADSEGLMLLTDDGELQHAISH 62 +ILFNKPY V+ QF+ + R+TL +++ + +Y AGRLD DSEGL++LT++G LQ ++ Sbjct: 41 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 100 Query: 63 PKRKQPKVYLVQVEGTPDANSLERLRNPLDLGDFVTRKSEVRHVQEPAWLWPRNPPIRER 122 P ++ K+Y VQVEG P ++LE LRN + L D T + V EPAWLWPRNPPIRER Sbjct: 101 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 160 Query: 123 KNHPTSWLTIQISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFALATDPLLPGEWK 177 K+ PTSWL I + EG+NRQVRRMTA VG PTLRL+R A+G ++L D L GEW+ Sbjct: 161 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSL--DNLANGEWR 213