BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0577.p (428 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PM1365 [S] COG3395 Uncharacterized protein conserved in bacteria... 390 e-108 HI1011 [S] COG3395 Uncharacterized protein conserved in bacteria... 384 e-106 BMEII1091 [S] COG3395 Uncharacterized protein conserved in bacte... 364 e-100 STM2917 [S] COG3395 Uncharacterized protein conserved in bacteri... 349 8e-96 ygbK [S] COG3395 Uncharacterized protein conserved in bacteria E... 323 4e-88 >PM1365 [S] COG3395 Uncharacterized protein conserved in bacteria Pmu Pasteurella multocida Length = 413 Score = 390 bits (1002), Expect = e-108, Method: Compositional matrix adjust. Identities = 211/412 (51%), Positives = 269/412 (65%), Gaps = 9/412 (2%) Query: 7 LLGCIADDFTGATDLANMLVRGGMRTVQTIGIPEQLPAVAADALVIALKSRTIPAAEAVE 66 +LG IADDFTGA+D+A+ LV G+ TVQ G+P+Q DA+VI+LKSR+ P EA+ Sbjct: 1 MLGVIADDFTGASDIASFLVENGLATVQMNGVPKQSLTAPVDAIVISLKSRSNPVDEAIA 60 Query: 67 QSLAALRWLQQQGCTQFFFKYCSTFDSTDAGNIGQVTDALLKELGADFTIACPAFPENGR 126 QSL AL WLQQQGCTQF+FKYCSTFDST GNIG VTDALL L ADFTI CPA P NGR Sbjct: 61 QSLQALHWLQQQGCTQFYFKYCSTFDSTAKGNIGPVTDALLDALSADFTIICPALPVNGR 120 Query: 127 TIYRGYLFVADGLLNESGMENHPLTPMTDANLVRVLQRQTESKVGLVRYDTVAKDAAAVT 186 TI+ GYLFV + LLNESGM+NHP+TPM DANLVR++ +Q K GLVRY + K + V Sbjct: 121 TIFNGYLFVGEVLLNESGMQNHPITPMKDANLVRLMDQQARGKTGLVRYADLLKGSDYVK 180 Query: 187 ERFTALRTDGVKMAIADAVSDRDLYVLGEACAELKLVTGGSGIALGLPENFRRAGLLHAS 246 F L+ G + A+ D+V + L VL EA +LKLVTGGSG+A + R +G H Sbjct: 181 SCFRTLQQQGFRYAVVDSVDNDQLAVLAEAITDLKLVTGGSGLAAYMAA--RASGGQH-- 236 Query: 247 AEAAQLPQVGGLSAVLAGSASKATNAQVAEWTARHPAWRIDPLALARGEAVVAQALA-FA 305 + A LP G + VL+GS S TN QVA++ + P + +D + + A LA + Sbjct: 237 GDNALLPPKGK-TVVLSGSCSVMTNKQVAKYAEKAPHFYLD-VEQSLSNPAYADVLAKWV 294 Query: 306 DEHISKE-AVLIYATATPDEVKAVQKELGVAKAGHLVEQALADIARGLRERGVRRFVVAG 364 H+ + A ++YAT +PD++K +Q E GV KA +E A +A+ L+ GV F+ AG Sbjct: 295 IAHLDHDLAPMVYATVSPDKLKQIQAEFGVEKASQAIENTFAQLAQKLKAAGVVNFITAG 354 Query: 365 GETSGAVVQALDVRALRIGPQIDPGVPATATLDDQPLALALKSGNFGSVDFF 416 GETS VVQ L +IG QI PGVP LD+ + LALKSGNFG+ DFF Sbjct: 355 GETSSIVVQQLGFTGFQIGKQIAPGVPWLKALDED-IYLALKSGNFGTEDFF 405 >HI1011 [S] COG3395 Uncharacterized protein conserved in bacteria Hin Haemophilus influenzae Length = 413 Score = 384 bits (987), Expect = e-106, Method: Compositional matrix adjust. Identities = 201/414 (48%), Positives = 259/414 (62%), Gaps = 7/414 (1%) Query: 7 LLGCIADDFTGATDLANMLVRGGMRTVQTIGIPEQLPAVAADALVIALKSRTIPAAEAVE 66 +LG IADDFTGA+D+A+ LV G+ TVQ G+P Q DA+VI+LKSR+ P EA+E Sbjct: 1 MLGVIADDFTGASDIASFLVENGLSTVQMNGVPTQSLNSKVDAIVISLKSRSNPVNEAIE 60 Query: 67 QSLAALRWLQQQGCTQFFFKYCSTFDSTDAGNIGQVTDALLKELGADFTIACPAFPENGR 126 QSL A +WL++ GCTQF+FKYCSTFDST GNIG VTDALL EL DFT+ PA P NGR Sbjct: 61 QSLRAYQWLKENGCTQFYFKYCSTFDSTAKGNIGPVTDALLDELNEDFTVITPALPVNGR 120 Query: 127 TIYRGYLFVADGLLNESGMENHPLTPMTDANLVRVLQRQTESKVGLVRYDTVAKDAAAVT 186 TI+ GYLFV D LL+ESGM+NHP+TPM DANL+R++ Q + K GLV Y V K A+ V Sbjct: 121 TIFNGYLFVGDVLLSESGMKNHPITPMVDANLMRLMDAQAKGKTGLVAYADVIKGASRVQ 180 Query: 187 ERFTALRTDGVKMAIADAVSDRDLYVLGEACAELKLVTGGSGIALGLPENFRRAGLLHAS 246 E F L+ G + A+ DAV + L VL EA A+ KLVTGGSG+ + A L Sbjct: 181 ECFAELKAQGYRYAVVDAVDNSQLEVLAEAVADFKLVTGGSGLGA-----YMAARLSGGK 235 Query: 247 AEAAQLPQVGGLSAVLAGSASKATNAQVAEWTARHPAWRIDPLALARGEAVVAQALAFAD 306 G + VL+GS S TN QV ++ + P +++D E + Q + Sbjct: 236 KGTNAFTPTKGKTVVLSGSCSVMTNKQVEKYREKAPHFQLDVEQAIHNENYIEQLYQWVI 295 Query: 307 EHISKE-AVLIYATATPDEVKAVQKELGVAKAGHLVEQALADIARGLRERGVRRFVVAGG 365 ++ E A ++YAT PD +KA+Q + GV +A H +E A +A L++ GV F+ AGG Sbjct: 296 ANLDSEFAPMVYATVPPDALKAIQHQFGVDQASHAIENTFAKLAAKLKQYGVTNFITAGG 355 Query: 366 ETSGAVVQALDVRALRIGPQIDPGVPATATLDDQPLALALKSGNFGSVDFFEKA 419 ETS VVQ L IG QI PGVP +++ + LALKSGNFG DFFE A Sbjct: 356 ETSSIVVQELGFTGFHIGKQIAPGVPWLKAVEED-IFLALKSGNFGKEDFFEYA 408 >BMEII1091 [S] COG3395 Uncharacterized protein conserved in bacteria Bme Brucella melitensis Length = 436 Score = 364 bits (934), Expect = e-100, Method: Compositional matrix adjust. Identities = 201/417 (48%), Positives = 277/417 (66%), Gaps = 4/417 (0%) Query: 8 LGCIADDFTGATDLANMLVRGGMRTVQTIGIPEQLPAVAADALVIALKSRTIPAAEAVEQ 67 LG IADDFTGATD+A LV G+RT+Q G+P AV ADA+VI+LK+R+ P +A+ + Sbjct: 15 LGVIADDFTGATDIAGFLVGNGLRTIQLNGVPADDLAVDADAVVISLKARSCPTGQAIAE 74 Query: 68 SLAALRWLQQQGCTQFFFKYCSTFDSTDAGNIGQVTDALLKELGADFTIACPAFPENGRT 127 SLAAL+WLQ+ C QFFFKYCSTFDST GNIG VTDALL+ LG +FT+ CPA P NGRT Sbjct: 75 SLAALKWLQKNNCQQFFFKYCSTFDSTPKGNIGPVTDALLEALGEEFTVICPALPVNGRT 134 Query: 128 IYRGYLFVADGLLNESGMENHPLTPMTDANLVRVLQRQTESKVGLVRYDTVAKDAAAVTE 187 IY GYLFV LL+E+GM NHP+TPMTD+N++RV++ Q+ + G + V + + AV + Sbjct: 135 IYNGYLFVNGVLLSETGMRNHPVTPMTDSNIMRVMESQSRGRAGNISSTIVDQGSDAVRD 194 Query: 188 RFTALRTDGVKMAIADAVSDRDLYVLGEACAELKLVTGGSGIALGLPENFRRAGLLHASA 247 L+++G++ A+ DA++D+ + LG A +++KLVTGGSG+A G+ + + + +A Sbjct: 195 ALRKLQSEGIRYAVLDALNDQHIETLGRAVSQMKLVTGGSGLADGMARAWTQLRGKNVAA 254 Query: 248 EAAQLPQVGGLSAVLAGSASKATNAQVAEWTARHPAWRIDPLALARGEAVVAQALAFADE 307 A V G + +L+GS S+ TNAQVA + A+ PA +D + A +A LA Sbjct: 255 AEAAGAPVKGRTVILSGSCSQMTNAQVAAYKAKAPALAMD-VEKAINDAAYIDVLAEWVL 313 Query: 308 HISKEAV--LIYATATPDEVKAVQKELGVAKAGHLVEQALADIARGLRERGVRRFVVAGG 365 S +A+ L+YAT P+ +KAVQ+ G +A +E +A+ L G RF+VAGG Sbjct: 314 AQSGDALPPLVYATMPPEALKAVQERFGGERASAAIEDLFGQLAKRLEAEGFTRFIVAGG 373 Query: 366 ETSGAVVQALDVRALRIGPQIDPGVPATATLDDQPLALALKSGNFGSVDFFEKALRF 422 ETSGAV QAL + IGPQI PGVP + +PL+LALKSGNFG+ FF +A + Sbjct: 374 ETSGAVTQALAIDGFTIGPQIAPGVPWVRGI-GKPLSLALKSGNFGTEAFFFEAQKI 429 >STM2917 [S] COG3395 Uncharacterized protein conserved in bacteria Sty Salmonella typhimurium LT2 Length = 420 Score = 349 bits (895), Expect = 8e-96, Method: Compositional matrix adjust. Identities = 191/417 (45%), Positives = 263/417 (63%), Gaps = 7/417 (1%) Query: 8 LGCIADDFTGATDLANMLVRGGMRTVQTIGIPEQLPAVAADALVIALKSRTIPAAEAVEQ 67 +G IADDFTGATD+A+ LV GM TVQ +P DA+VI+LK+R+ PA EA++Q Sbjct: 4 IGVIADDFTGATDIASFLVENGMPTVQINDVPTGTQPEGCDAVVISLKTRSCPAQEAIKQ 63 Query: 68 SLAALRWLQQQGCTQFFFKYCSTFDSTDAGNIGQVTDALLKELGADFTIACPAFPENGRT 127 SLAAL WL++QGC Q +FKYCSTFDST GNIG VTDAL+ L FT+ PA P NGRT Sbjct: 64 SLAALVWLKKQGCQQVYFKYCSTFDSTAEGNIGPVTDALMVALDTSFTVISPALPVNGRT 123 Query: 128 IYRGYLFVADGLLNESGMENHPLTPMTDANLVRVLQRQTESKVGLVRYDTVAKDAAAVTE 187 +Y+GYLFV + LL ESGM +HP+ PMTD+ L R+++ Q + + G++ T+ + AA Sbjct: 124 VYQGYLFVMNHLLAESGMRHHPINPMTDSYLPRLMEAQAQGRCGVIPAQTLDEGVAATRA 183 Query: 188 RFTALRTDGVKMAIADAVSDRDLYVLGEACAELKLVTGGSGIALGLPENFRRAGLLHASA 247 + L+ +G + A+ DA+++R L + GE + LVTGGSG+A+GL + + G+ + A Sbjct: 184 ALSRLQQEGYRYAVLDALNERHLEIQGEVLRDAPLVTGGSGLAMGLARQWAKHGV--SQA 241 Query: 248 EAAQLPQVGGLSAVLAGSASKATNAQVAEWTARHPAWRIDPLALARGEAVVAQALAFADE 307 +A P + G + VL+GS S+ TN QVA + P +D E A A A A Sbjct: 242 RSAGYP-LSGRAVVLSGSCSQMTNQQVAFYRQHAPTRDVDVARCLSSETREAYAEALAQW 300 Query: 308 HISKE---AVLIYATATPDEVKAVQKELGVAKAGHLVEQALADIARGLRERGVRRFVVAG 364 +S++ A +I ATA+ + A+Q++ G +A H VE + +A L E G+ RF+VAG Sbjct: 301 VLSQDSELAPMISATASTQALAAIQQQYGATEASHAVEALFSLLAARLAEGGITRFIVAG 360 Query: 365 GETSGAVVQALDVRALRIGPQIDPGVPATATLDDQPLALALKSGNFGSVDFFEKALR 421 GETSG V Q+L + IGP I PGVP L P++LALKSGNFG FF +A R Sbjct: 361 GETSGVVTQSLGITGFHIGPCISPGVPWVNAL-HAPVSLALKSGNFGDESFFIRAQR 416 >ygbK [S] COG3395 Uncharacterized protein conserved in bacteria Eco Escherichia coli K12 Length = 388 Score = 323 bits (829), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 176/384 (45%), Positives = 238/384 (61%), Gaps = 6/384 (1%) Query: 8 LGCIADDFTGATDLANMLVRGGMRTVQTIGIPEQLPAVAADALVIALKSRTIPAAEAVEQ 67 +G IADDFTGATD+A+ LV G+ TVQ G+P A DALVI+LK+R+ P EA +Q Sbjct: 4 IGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAIDALVISLKTRSCPVVEATQQ 63 Query: 68 SLAALRWLQQQGCTQFFFKYCSTFDSTDAGNIGQVTDALLKELGADFTIACPAFPENGRT 127 SLAAL WLQQQGC Q +FKYCSTFDST GNIG VTDAL+ L FT+ PA P NGRT Sbjct: 64 SLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDALMDALDTPFTVFSPALPVNGRT 123 Query: 128 IYRGYLFVADGLLNESGMENHPLTPMTDANLVRVLQRQTESKVGLVRYDTVAKDAAAVTE 187 +Y+GYLFV + LL ESGM +HP+ PMTD+ L R+++ Q+ + G+V + AV + Sbjct: 124 VYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEAQSTGRCGVVSAHVFEQGVDAVRQ 183 Query: 188 RFTALRTDGVKMAIADAVSDRDLYVLGEACAELKLVTGGSGIALGLPENFRRAGLLHASA 247 L+ +G + A+ DA+++ L + GEA + LVTGGSG+A+GL + + A Sbjct: 184 ELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPLVTGGSGLAIGLARQWAQEN--GNQA 241 Query: 248 EAAQLPQVGGLSAVLAGSASKATNAQVAEWTARHPAWRIDPLALARGEAVVAQALAFADE 307 A P + G VL+GS S+ TN QVA + PA +D E + A A A+ Sbjct: 242 RKAGRP-LAGRGVVLSGSCSQMTNRQVAHYRQIAPAREVDVARCLSIETLAAYAHELAEW 300 Query: 308 HISKEAV---LIYATATPDEVKAVQKELGVAKAGHLVEQALADIARGLRERGVRRFVVAG 364 + +E+V L++ATA+ D + A+Q++ G KA VE + +A L GV RF+VAG Sbjct: 301 VLGQESVLAPLVFATASTDALAAIQQQYGAQKASQAVETLFSQLAARLAAEGVTRFIVAG 360 Query: 365 GETSGAVVQALDVRALRIGPQIDP 388 GETSG V Q+L ++ IGP I P Sbjct: 361 GETSGVVTQSLGIKGFHIGPTISP 384