BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0559.p (706 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2971 Non COG 681 0.0 PA5040 [U] COG4796 Type II secretory pathway, component HofQ Pae... 439 e-123 NMB1812 [U] COG4796 Type II secretory pathway, component HofQ Nm... 391 e-108 NMA0650 [U] COG4796 Type II secretory pathway, component HofQ Nm... 391 e-108 VC2630 [U] COG4796 Type II secretory pathway, component HofQ Vch... 359 2e-98 >RSc2971 Non COG Length = 714 Score = 681 bits (1758), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/712 (51%), Positives = 474/712 (66%), Gaps = 32/712 (4%) Query: 8 LALLTMFCLLAGSGAHIHVHAQA-QRNAIVAIDVAQRDARTEVRIKLRTPPATSPVHFST 66 +A L++ L+ G A A NA+ ++ A T V + L+ PA PV FST Sbjct: 22 VAWLSLCMLMVGGQALAQQAITAPASNAVERVEQASTGESTVVTVTLKDTPAQKPVEFST 81 Query: 67 ASPARIVIDLADT---DNSADVQTPGADNNSGALRGVTIASSAGRSRVVLNLRHMPPYSV 123 PARI ID T A+ Q G LR ++ R+RVVL+L Y Sbjct: 82 QQPARIAIDFFGTAFAQGRANYQYGGK-----LLRAASVVQIGDRTRVVLDLARQSQYKS 136 Query: 124 RTEGDTVIATI--------TAITTIAASAASAGNEAPPTGARPSIGSIDFRRGAQGEGRI 175 G+ + T+ T + T AA A +AG E RPS+ +IDFRRG + GR+ Sbjct: 137 EIRGNQYVLTLGAAPTASATPVPTFAAPAPTAGVE------RPSVRNIDFRRGEELAGRV 190 Query: 176 IIDLPGPETALDIRQQGRQIVADILNAGVPARAPRRLDVSDFGTPVKTIASSDRGTDVRL 235 ++DL +A++I QQG+ +V D A +P RR DVSDFGTPV+ + ++D GT RL Sbjct: 191 VVDLSTSNSAINIAQQGQNLVVDFAGATLPQSLRRRFDVSDFGTPVQAMRATDNGTGARL 250 Query: 236 LIDTEALAEYHAYQKEAQLVIEVRNPADAEKRAAQRQQPYRGDKLSLQFQNIEVRAILQV 295 +I+ +Y +YQ + Q V+EVR P + YRG+++SL FQNI++R++LQV Sbjct: 251 VIEPRGNWQYSSYQTDTQFVVEVR-PTKEDPNKLISGPGYRGERMSLNFQNIDIRSLLQV 309 Query: 296 LADFTGINIIASDGVGGALTLRLKEVPWDQALDIVLQARGLDMRRNGNVMWVAPREELLT 355 ADFT +NI+ SD V G L+LRLK+VPWDQAL IVL ++GL RRNGNV+WVAPR EL T Sbjct: 310 FADFTNLNIVTSDSVTGTLSLRLKDVPWDQALQIVLDSKGLASRRNGNVLWVAPRNELAT 369 Query: 356 RERLELEQRAQIAELEPLRAEVFQLNYQKAEAFRKIFGEDVAAGISTASERRPTLLSRRG 415 +E+ ELE + Q+ ELEPLR++VF+LNYQ+A+ R + A+ R +LS+RG Sbjct: 370 KEKAELESQQQVTELEPLRSQVFRLNYQRADDVRNMLLGTGGTAGGGAAASR--ILSKRG 427 Query: 416 SAVVDQRTNQLFVTDTPSVLDNIRKLLEKIDVASRQVLIEARIVEADDSFSRNLGARLGF 475 S D RTNQLFV+D PS L+ ++ L KID+ RQV+IEARIVEADD+FSRNLGA+LGF Sbjct: 428 SLTSDARTNQLFVSDIPSKLEEVQAFLLKIDIPVRQVMIEARIVEADDTFSRNLGAKLGF 487 Query: 476 SAKANGIAAGSSYNQAGEVAGLTPAVAN-SYSANHAVNLPAQGIGGAAAGSFALSLFNAA 534 +AK NG G++Y+ ++P + ++ + AV+LPA GI G A S A+SLFNA Sbjct: 488 AAKTNGAGYGNTYSNV-----VSPVTKDATWDNSAAVSLPANGINGVNAASVAVSLFNAG 542 Query: 535 ANRFLTLELSALEADGKGKIVSSPRVVTADQQPALIEQGEEIPYQQATSSGATSTAFKKA 594 A RFL LELSALEADG+GKI+SSPRVVTAD ALIEQG E+PYQQATSSGATS +FKKA Sbjct: 543 AGRFLALELSALEADGRGKIISSPRVVTADNIKALIEQGTEVPYQQATSSGATSVSFKKA 602 Query: 595 NLKLEVTPQITPDGNVILSVDINKDSRGTATPGGLAINTKHVKTLVQVENGGTVVIGGIY 654 NLKLEVTP+ITPDGNV L VD+NKDS GT T G AINTKHV+T V VENGGTVVIGGIY Sbjct: 603 NLKLEVTPKITPDGNVFLDVDVNKDSLGTQTTNGFAINTKHVQTQVLVENGGTVVIGGIY 662 Query: 655 TQTESNTVSKVPLLGDIPVLGNLFRHSARIDHKTELLIFLTPKIVADRNFLR 706 TQ E V+KVPLLGDIPVLGNLF+ +A+ + +TELL+FLTP++++D+ L+ Sbjct: 663 TQNERTDVNKVPLLGDIPVLGNLFKSTAKTNDRTELLVFLTPRVLSDQLSLK 714 >PA5040 [U] COG4796 Type II secretory pathway, component HofQ Pae Pseudomonas aeruginosa Length = 714 Score = 439 bits (1130), Expect = e-123, Method: Compositional matrix adjust. Identities = 274/705 (38%), Positives = 407/705 (57%), Gaps = 52/705 (7%) Query: 34 AIVAIDVAQRDA------RTEVRIKLRTPPATSPVHFSTASPARIVIDLADTDNSADVQT 87 A++A D+ + D R E++++ P A +P ++ PARI +DL N + T Sbjct: 20 ALLAADLEKLDVAALPGDRVELKLQFDEPVA-APRGYTIEQPARIALDLPGVQNK--LGT 76 Query: 88 PGADNNSGALRGVTIASSAGRSRVVLNLRHMPPYSVRTEGDT---VIATITAITTIAASA 144 + + G R VT+ + R+R+++NL + Y+ R EG+ V+ A ++A++A Sbjct: 77 KNRELSVGNTRSVTVVEAKDRTRLIINLTALSSYTTRVEGNNLFVVVGNSPAGASVASAA 136 Query: 145 ASAGNEAPPTGARP-----------SIGSIDFRRGAQGEGRIIIDLPGPETALDIRQQGR 193 + AP + A+P +I +IDF+RG +GEG ++IDL P + DI++QG Sbjct: 137 PVKASPAPASYAQPIKPKPYVPAGRAIRNIDFQRGEKGEGNVVIDLSDPTLSPDIQEQGG 196 Query: 194 QIVADILNAGVPARAPRRLDVSDFGTPVKTIASSDRGTDVRLLIDTEALAEYHAYQKEAQ 253 +I D +P RLDV DF TPV+ + +S + + I+ L +Y YQ + + Sbjct: 197 KIRLDFAKTQLPDALRVRLDVKDFATPVQFVNASAQSDRTSITIEPSGLYDYLVYQTDNR 256 Query: 254 LVIEVR--NPADAEKRAAQRQQPYRGDKLSLQFQNIEVRAILQVLADFTGINIIASDGVG 311 L + ++ DAE+R + Y G+KLSL FQ+I+VR++LQ++ADFT +N++ASD V Sbjct: 257 LTVSIKPMTTEDAERRK-KDNFAYTGEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQ 315 Query: 312 GALTLRLKEVPWDQALDIVLQARGLDMRRNGNVMWVAPREELLTRERLELEQRAQIAELE 371 G +TLRL+ VPWDQALD+VL+ +GLD R+ GNV+ VAP +E+ RER ELE + QIAEL Sbjct: 316 GNITLRLQNVPWDQALDLVLKTKGLDKRKLGNVLLVAPADEIAARERQELEAQKQIAELA 375 Query: 372 PLRAEVFQLNYQKAEAFRKIFGEDVAAGISTASERRPTLLSRRGSAVVDQRTNQLFVTDT 431 PLR E+ Q+NY KA K+F + G E RGS VD RTN + Sbjct: 376 PLRRELIQVNYAKAADIAKLFQSVTSDGGQEGKE------GGRGSITVDDRTNSIIAYQP 429 Query: 432 PSVLDNIRKLLEKIDVASRQVLIEARIVEADDSFSRNLGARLGFSA-KANGIAAGSSYN- 489 LD +R+++ ++D+ RQV+IEARIVEA+ + ++LG R G + K N G N Sbjct: 430 QERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNWSGYGKDGNI 489 Query: 490 --------QAGEVAGLT--PAVANSYSANHAVNLPAQGIGGAAAGSFALSLFNAAANRFL 539 G +AG P S S + V+L GA + + + N L Sbjct: 490 GIKDEDGMNCGPIAGSCTFPTTGTSKSPSPFVDL------GAKDATSGIGIGFITDNIIL 543 Query: 540 TLELSALEADGKGKIVSSPRVVTADQQPALIEQGEEIPYQQATSSGATSTAFKKANLKLE 599 L+LSA+E G G+IVS P+VVT+D++ A I +G E+PYQ+A+SSGATST+FK+A L LE Sbjct: 544 DLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGSEVPYQEASSSGATSTSFKEAALSLE 603 Query: 600 VTPQITPDGNVILSVDINKDS--RGTATPGGLAINTKHVKTLVQVENGGTVVIGGIYTQT 657 VTPQITPD +I+ V + KD+ G IN V + V +G T+VIGG+++ Sbjct: 604 VTPQITPDNRIIVEVKVTKDAPDYQNMLNGVPPINKNEVNAKILVNDGETIVIGGVFSNE 663 Query: 658 ESNTVSKVPLLGDIPVLGNLFRHSARIDHKTELLIFLTPKIVADR 702 +S +V KVP LG++P LG LFR D K ELL+FLTP+I+ ++ Sbjct: 664 QSKSVEKVPFLGELPYLGRLFRRDTVTDRKNELLVFLTPRIMNNQ 708 >NMB1812 [U] COG4796 Type II secretory pathway, component HofQ Nme Neisseria meningitidis MC58 Length = 769 Score = 391 bits (1005), Expect = e-108, Method: Compositional matrix adjust. Identities = 232/549 (42%), Positives = 328/549 (59%), Gaps = 26/549 (4%) Query: 162 SIDFRRGAQGEGRIIIDLPGPETALDIRQQGRQIVADILNAGVPARAPRRLDVSDFGTPV 221 +IDFR+ + G I + G DI QQ I+ + N +P R LDV+DF TPV Sbjct: 227 NIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPV 286 Query: 222 KTIASSDRGTDVRLLIDTEALAEYHAYQKEA---QLVIEVRNPADAEKRAAQRQQP--YR 276 + + D +L+I T + K A +V + P + Sbjct: 287 QKVTLKRLNNDTQLIITTAG--NWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKTFT 344 Query: 277 GDKLSLQFQNIEVRAILQVLADFTGINIIASDGVGGALTLRLKEVPWDQALDIVLQARGL 336 G K+SL FQ++E+R ILQ+LA +G+NI+ASD V G +TL LK+VPWDQALD+V+QAR L Sbjct: 345 GRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNL 404 Query: 337 DMRRNGNVMWVAPREELLTRERLELEQRAQIAELEPLRAEVFQLNYQKAEAFRKIFGEDV 396 DMR+ GN++ +APR+ELL +++ L+ IA+L L ++ FQL Y+ E FR I D Sbjct: 405 DMRQQGNIVNIAPRDELLAKDKALLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDN 464 Query: 397 AAGISTASERRPTLLSRRGSAVVDQRTNQLFVTDTPSVLDNIRKLLEKIDVASRQVLIEA 456 A + R TL+S RGS ++D TN L VTDT SV++ RKL++++DV ++QV+IEA Sbjct: 465 A----DTTGNRNTLISGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMIEA 520 Query: 457 RIVEADDSFSRNLGARLGFSAKANGIAAGSSYNQAGEVAGLTPAVANSYSANHAVNLPAQ 516 RIVEA D FSR+LG + G + K S++ G +G + + A +NLP Sbjct: 521 RIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGW-GVNSGF--GGDDKWGAETKINLPIT 577 Query: 517 GIGGAAAGSFALSLFNAAANRFLTLELSALEADGKGKIVSSPRVVTADQQPALIEQGEEI 576 AAA S +SL A ++ L LELSA E+ K K +++PRV+T +++ A IE G EI Sbjct: 578 ----AAANS--ISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEI 631 Query: 577 PY---QQATSSGATSTAFKKANLKLEVTPQITPDGNVILSVDINKDSRGTATPGG---LA 630 P+ A +T+T KKA L L VTP ITPDG +I++V INKDS G L Sbjct: 632 PFTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILC 691 Query: 631 INTKHVKTLVQVENGGTVVIGGIYTQTESNTVSKVPLLGDIPVLGNLFRHSARIDHKTEL 690 I+TK++ T VENGGT+++GGIY + NT++KVPLLGDIPV+GNLF+ + + EL Sbjct: 692 ISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRREL 751 Query: 691 LIFLTPKIV 699 LIF+TP+I+ Sbjct: 752 LIFITPRIM 760 >NMA0650 [U] COG4796 Type II secretory pathway, component HofQ NmA Neisseria meningitidis Z2491 Length = 761 Score = 391 bits (1004), Expect = e-108, Method: Compositional matrix adjust. Identities = 233/551 (42%), Positives = 332/551 (60%), Gaps = 30/551 (5%) Query: 162 SIDFRRGAQGEGRIIIDLPGPETALDIRQQGRQIVADILNAGVPARAPRRLDVSDFGTPV 221 +IDFR+ + G I + G DI QQ I+ + N +P R LDV+DF TPV Sbjct: 219 NIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPV 278 Query: 222 KTIASSDRGTDVRLLIDTEALAEYHAYQKEA-------QLVIEVRNPADAEKRAAQRQQP 274 + + D +L+I T + K A Q++ + +N A + Sbjct: 279 QKVTLKRLNNDTQLIITTAG--NWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKT-- 334 Query: 275 YRGDKLSLQFQNIEVRAILQVLADFTGINIIASDGVGGALTLRLKEVPWDQALDIVLQAR 334 + G K+SL FQ++E+R ILQ+LA +G+NI+ASD V G +TL LK+VPWDQALD+V+QAR Sbjct: 335 FTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQAR 394 Query: 335 GLDMRRNGNVMWVAPREELLTRERLELEQRAQIAELEPLRAEVFQLNYQKAEAFRKIFGE 394 LDMR+ GN++ +APR+ELL +++ L+ IA+L L ++ FQL Y+ E FR I Sbjct: 395 NLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRL 454 Query: 395 DVAAGISTASERRPTLLSRRGSAVVDQRTNQLFVTDTPSVLDNIRKLLEKIDVASRQVLI 454 D A + R TL+S RGS ++D TN L VTDT SV++ RKL++++DV ++QV+I Sbjct: 455 DNA----DTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQVMI 510 Query: 455 EARIVEADDSFSRNLGARLGFSAKANGIAAGSSYNQAGEVAGLTPAVANSYSANHAVNLP 514 EARIVEA D FSR+LG + G + K S++ G +G + + A +NLP Sbjct: 511 EARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGW-GVNSGF--GGDDKWGAETKINLP 567 Query: 515 AQGIGGAAAGSFALSLFNAAANRFLTLELSALEADGKGKIVSSPRVVTADQQPALIEQGE 574 AAA S +SL A ++ L LELSA E+ K K +++PRV+T +++ A IE G Sbjct: 568 IT----AAANS--ISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGY 621 Query: 575 EIPY---QQATSSGATSTAFKKANLKLEVTPQITPDGNVILSVDINKDSRGTATPGG--- 628 EIP+ A +T+T KKA L L VTP ITPDG +I++V INKDS G Sbjct: 622 EIPFTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTI 681 Query: 629 LAINTKHVKTLVQVENGGTVVIGGIYTQTESNTVSKVPLLGDIPVLGNLFRHSARIDHKT 688 L I+TK++ T VENGGT+++GGIY + NT++KVPLLGDIPV+GNLF+ + + Sbjct: 682 LCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDRR 741 Query: 689 ELLIFLTPKIV 699 ELLIF+TP+I+ Sbjct: 742 ELLIFITPRIM 752 >VC2630 [U] COG4796 Type II secretory pathway, component HofQ Vch Vibrio cholerae Length = 578 Score = 359 bits (921), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 215/544 (39%), Positives = 315/544 (57%), Gaps = 21/544 (3%) Query: 162 SIDFRRGAQGEGRIIIDLPGPETALDIRQQGRQIVADILNAGVPARAPRRLDVSDFGTPV 221 +IDFR + +I++L P +D+++ + ++L V LDV DF TPV Sbjct: 48 NIDFRVNKEKAAVLIVELASPSAVVDVQKVQEGLSIELLKTDVADDKLYLLDVKDFSTPV 107 Query: 222 KTIA--SSDRGTDVRLLIDTEALAEYHAYQKEAQLVIEVRNPADAEKRAAQRQQPYRGDK 279 +++ + T + + +D E +Y K ++VI + AD EK + G Sbjct: 108 ESVEVFRKEPSTQLVVTVDGEFQHDYTLKGKYLEVVIS-KLKAD-EKPKPKSVLEKEGKL 165 Query: 280 LSLQFQNIEVRAILQVLADFTGINIIASDGVGGALTLRLKEVPWDQALDIVLQARGLDMR 339 +S+ FQ+I VR +LQ++AD+ G N++ SD V G LTLRL VPW Q LDI+LQ +GLD R Sbjct: 166 ISINFQDIPVRNVLQLIADYNGFNLVVSDSVVGNLTLRLDGVPWQQVLDIILQVKGLDKR 225 Query: 340 RNGNVMWVAPREELLTRERLELEQRAQIAELEPLRAEVFQLNYQKAEAFRKIFGEDVAAG 399 +GNV+ +AP+EEL RE+ LE+ EL L++E+ ++N+ KA D+AA Sbjct: 226 VDGNVILIAPKEELDLREKQALEKARLAEELGDLKSEIIKINFAKA--------SDIAAM 277 Query: 400 ISTASERRPTLLSRRGSAVVDQRTNQLFVTDTPSVLDNIRKLLEKIDVASRQVLIEARIV 459 I E +LS RGS +D+RTN L + + P + IR+++E +D+ +QV IEARIV Sbjct: 278 I--GGEGNVNMLSERGSISIDERTNSLLIRELPDNIAVIREIIESLDIPVKQVQIEARIV 335 Query: 460 EADDSFSRNLGARLGFSAKANGIAAGSSYNQAGEVAGLTPAVANSYSANHAVNLPAQGIG 519 + LG R G + + G S GL VNL + Sbjct: 336 TVKEGNLEELGVRWGVMSTNGSHSVGGSIESNLWQKGLLADDEFPVDEFLNVNLAST--- 392 Query: 520 GAAAGSFALSLFNAAANRFLTLELSALEADGKGKIVSSPRVVTADQQPALIEQGEEIPYQ 579 A A S A + + L LELSAL+ + K +I+SSPR++T ++QPA IEQG EIPY Sbjct: 393 SANASSIAFQVAKLGSGTLLDLELSALQNESKAEIISSPRLITTNKQPAYIEQGTEIPYL 452 Query: 580 QATSSGATSTAFKKANLKLEVTPQITPDGNVILSVDINKDSRG----TATPGGLAINTKH 635 +++SSGA++ AFKKA L L+VTPQITPD ++L + + +D RG T T ++I+T+ Sbjct: 453 ESSSSGASTVAFKKAVLSLKVTPQITPDNRLVLDLSVTQDRRGETVKTGTGEAVSIDTQR 512 Query: 636 VKTLVQVENGGTVVIGGIYTQTESNTVSKVPLLGDIPVLGNLFRHSARIDHKTELLIFLT 695 + T V V NG TVV+GGI+ + +N+V KVPLLGD+PVLG LFR + K+ELLIF+T Sbjct: 513 IGTQVLVNNGETVVLGGIFQHSINNSVDKVPLLGDLPVLGALFRRTYEQMGKSELLIFVT 572 Query: 696 PKIV 699 PK+V Sbjct: 573 PKVV 576