BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0546.p         (161 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc0309 [M] COG2870 ADP-heptose synthase, bifunctional sugar kin...   193   1e-49
NMA0356 [M] COG2870 ADP-heptose synthase, bifunctional sugar kin...   143   2e-34
NMB2076 [M] COG2870 ADP-heptose synthase, bifunctional sugar kin...   141   5e-34
HI1526 [M] COG2870 ADP-heptose synthase, bifunctional sugar kina...   127   1e-29
YPO0654 [M] COG2870 ADP-heptose synthase, bifunctional sugar kin...   127   1e-29

>RSc0309 [M] COG2870 ADP-heptose synthase, bifunctional sugar
           kinase/adenylyltransferase Rso Ralstonia solanacearum
          Length = 166

 Score =  193 bits (491), Expect = 1e-49,   Method: Compositional matrix adjust.
 Identities = 93/140 (66%), Positives = 113/140 (80%)

Query: 4   FEKKICSRADLQARVAALPQPVVLTNGVFDILHRGHVTYLAQARAEGASLVVAANTDASV 63
           FE+K+C  AD++ARV ALP+P+V TNGVFDILHRGHVTYLAQARA GASLVV  NTDASV
Sbjct: 11  FEQKLCDSADVEARVRALPRPLVFTNGVFDILHRGHVTYLAQARALGASLVVGVNTDASV 70

Query: 64  KRLGKGDDRPINTCEDRMAVLAALESVSLVVPFDEDTALEVVQEARPQIYVKGGDYDMSA 123
           + LGKGDDRP+N   DR+AVLAALESVSLVV F E T +E+++  RP IYVKGGDYD+  
Sbjct: 71  RMLGKGDDRPLNAEVDRLAVLAALESVSLVVLFAERTPVELIRRVRPDIYVKGGDYDIDT 130

Query: 124 IPEGQAVAAYGGKSVAIAFE 143
           + E + V  +GG ++AI F+
Sbjct: 131 LEETRVVRGWGGTALAIPFD 150


>NMA0356 [M] COG2870 ADP-heptose synthase, bifunctional sugar
           kinase/adenylyltransferase NmA Neisseria meningitidis
           Z2491
          Length = 168

 Score =  143 bits (360), Expect = 2e-34,   Method: Compositional matrix adjust.
 Identities = 82/140 (58%), Positives = 98/140 (70%)

Query: 3   DFEKKICSRADLQARVAALPQPVVLTNGVFDILHRGHVTYLAQARAEGASLVVAANTDAS 62
           DFE KIC    L AR+A LP+P+V TNG FDILHRGHVTYLAQAR+ G +LV+A NTDAS
Sbjct: 9   DFESKICPPEALAARLALLPRPLVFTNGCFDILHRGHVTYLAQARSMGGALVLALNTDAS 68

Query: 63  VKRLGKGDDRPINTCEDRMAVLAALESVSLVVPFDEDTALEVVQEARPQIYVKGGDYDMS 122
           V+RLGKG DRPIN  E+R AV AALESV LV  FD DT   +++  +P+I VKGGD+   
Sbjct: 69  VRRLGKGGDRPINPLENRAAVAAALESVDLVTWFDGDTPAALIEAVKPEILVKGGDWAAD 128

Query: 123 AIPEGQAVAAYGGKSVAIAF 142
            I       A GG+  +I F
Sbjct: 129 KIVGAAETLARGGQVFSIPF 148


>NMB2076 [M] COG2870 ADP-heptose synthase, bifunctional sugar
           kinase/adenylyltransferase Nme Neisseria meningitidis
           MC58
          Length = 168

 Score =  141 bits (356), Expect = 5e-34,   Method: Compositional matrix adjust.
 Identities = 81/140 (57%), Positives = 98/140 (70%)

Query: 3   DFEKKICSRADLQARVAALPQPVVLTNGVFDILHRGHVTYLAQARAEGASLVVAANTDAS 62
           DFE KIC    L AR+A LP+P+V TNG FDILHRGHVTYLAQAR+ G +LV+A NTDAS
Sbjct: 9   DFESKICPPEALAARLALLPRPLVFTNGCFDILHRGHVTYLAQARSMGDALVLALNTDAS 68

Query: 63  VKRLGKGDDRPINTCEDRMAVLAALESVSLVVPFDEDTALEVVQEARPQIYVKGGDYDMS 122
           V+RLGKG DRP+N  E+R AV AALESV LV  FD DT   +++  +P+I VKGGD+   
Sbjct: 69  VRRLGKGGDRPVNPLENRAAVAAALESVDLVTWFDGDTPAALIEAVKPEILVKGGDWAAD 128

Query: 123 AIPEGQAVAAYGGKSVAIAF 142
            I       A GG+  +I F
Sbjct: 129 KIVGAAETLARGGQVFSIPF 148


>HI1526 [M] COG2870 ADP-heptose synthase, bifunctional sugar
           kinase/adenylyltransferase Hin Haemophilus influenzae
          Length = 476

 Score =  127 bits (319), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 71/141 (50%), Positives = 88/141 (62%), Gaps = 4/141 (2%)

Query: 8   ICSRADLQARVA---ALPQPVVLTNGVFDILHRGHVTYLAQARAEGASLVVAANTDASVK 64
           I S A+L+  VA   A  + +V+TNG FDILH GH++YL  AR  G  L+VA N+D SVK
Sbjct: 322 IMSEAELKDAVAQAKARGEKIVMTNGCFDILHPGHISYLENARKLGDRLIVAVNSDDSVK 381

Query: 65  RLGKGDDRPINTCEDRMAVLAALESVSLVVPFDEDTALEVVQEARPQIYVKGGDYDMSAI 124
           RL KG+ RPIN  E+RMAVLA L SV  +VPF EDT   ++ E  P + VKGGDY    I
Sbjct: 382 RL-KGESRPINNLENRMAVLAGLASVDWLVPFTEDTPQRLIGEILPDLLVKGGDYKPEEI 440

Query: 125 PEGQAVAAYGGKSVAIAFEXG 145
              + V A GG    + FE G
Sbjct: 441 AGSKEVWANGGDVKVLNFENG 461


>YPO0654 [M] COG2870 ADP-heptose synthase, bifunctional sugar
           kinase/adenylyltransferase Ype Yersinia pestis
          Length = 476

 Score =  127 bits (318), Expect = 1e-29,   Method: Compositional matrix adjust.
 Identities = 65/123 (52%), Positives = 82/123 (66%), Gaps = 1/123 (0%)

Query: 23  QPVVLTNGVFDILHRGHVTYLAQARAEGASLVVAANTDASVKRLGKGDDRPINTCEDRMA 82
           + VV+TNG+FDILH GHV+YLA AR  G  L+VA N+DAS KRL KG+ RP+N  E RM 
Sbjct: 340 EKVVMTNGIFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRL-KGEKRPVNPLEQRMV 398

Query: 83  VLAALESVSLVVPFDEDTALEVVQEARPQIYVKGGDYDMSAIPEGQAVAAYGGKSVAIAF 142
           VL ALE+V  VVPF+EDT   ++ +  P + VKGGDY    I   + V A GG+   + F
Sbjct: 399 VLGALEAVDWVVPFEEDTPQRLIADILPDLLVKGGDYKPHEIAGSEEVWAAGGEVKVLNF 458

Query: 143 EXG 145
           E G
Sbjct: 459 EDG 461