BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0537.p (313 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0360 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto... 241 2e-63 XF2099 [QR] COG0500 SAM-dependent methyltransferases Xfa Xylella... 156 5e-38 NMB0271 [QR] COG0500 SAM-dependent methyltransferases Nme Neisse... 99 1e-20 VC1114 [QR] COG0500 SAM-dependent methyltransferases Vch Vibrio ... 98 3e-20 NMA2215 [QR] COG0500 SAM-dependent methyltransferases NmA Neisse... 95 2e-19 >RSc0360 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia solanacearum Length = 367 Score = 241 bits (614), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 141/288 (48%), Positives = 176/288 (61%), Gaps = 18/288 (6%) Query: 33 ESDFLRREVSARMLERLLLIKIEPQRVLDAGCGEGADIAALQKRFSDAQVVGLDGAFNMV 92 E+DFL REV RM +RL IK+ P R LD GCG G +A L+ ++ DAQ+ GLD + M+ Sbjct: 79 EADFLLREVGQRMQDRLSYIKLTPARALDLGCGLGQGLAVLRAQYPDAQICGLDWSAAML 138 Query: 93 ALARE--HQLAAQSAVNRLLNKWLPAANPGGGASLACADFAQLPFAPNALDMVWSNLALH 150 A AR+ Q + + RLL K P + A ADF LPFA + D++WSNLALH Sbjct: 139 ARARQLDPQHSDGGWLGRLLKK-RPVFD------FAQADFRALPFADASFDLLWSNLALH 191 Query: 151 WHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTFKELRTAFEAVDADPHSLPFVDMHDFGDM 210 W P P +F EW RV GLLMFS FGPDT +ELR+A +DA H+L FVDMHD GDM Sbjct: 192 WDPSPHAIFPEWHRVTAEGGLLMFSLFGPDTLRELRSALAGIDASVHTLRFVDMHDIGDM 251 Query: 211 LVNAGFSTPVMDMEAITVTYDSPQRLLADLRAWGG--NPLESRRRGLX---VVVERLRGF 265 LV+ +STPVMDME IT+TY+SPQ LLAD+ GG + R L + R R Sbjct: 252 LVHGRWSTPVMDMEQITITYESPQALLADVHLLGGMAGLADGDGRALSGPGLYTPRWRQH 311 Query: 266 TLQALDRQRGADGKIPLSFEVIYGHAFR--PVPKTT--ASGEAIIRFD 309 ALD QR DG IPL+FEV+YGHA++ P P+ G A+I D Sbjct: 312 LFDALDAQRNPDGLIPLTFEVVYGHAWKLAPNPRQALDEQGRAMIPVD 359 >XF2099 [QR] COG0500 SAM-dependent methyltransferases Xfa Xylella fastidiosa 9a5c Length = 295 Score = 156 bits (395), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 115/295 (38%), Positives = 149/295 (50%), Gaps = 27/295 (9%) Query: 17 DLPLVRRLFSTPARVAESD-FLRREVSARMLERL-LLIKIEPQRVLDAGCGEGADIAALQ 74 D +RR FS AR +++ L+ EV R+LE L L P+ +LD G G G A++ Sbjct: 6 DTSHIRRAFSRAARSYDTNAILQHEVEQRLLESLDYLGDRIPRVILDVGAGTGRASIAMK 65 Query: 75 KRFSDAQVVGLDGAFNMVALAREHQLAAQSAVNRLLNKWLPAANPGGGASLACADFAQLP 134 KR+ AQV+ D A M+ AR+ + W P A C D LP Sbjct: 66 KRWPKAQVIAFDQAMPMLQEARKRS-----------HWWKPLAQ-------ICGDARTLP 107 Query: 135 FAPNALDMVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTFKELRTAFEAVDA 194 A ++D+++SNL L W VFA +R+ LR GLL+ S FGPDT ELR AF DA Sbjct: 108 VADASVDVIFSNLCLQWIEDLPTVFAGFRQALRPGGLLLCSLFGPDTLIELREAFAQADA 167 Query: 195 DPHSLPFVDMHDFGDMLVNAGFSTPVMDMEAITVTYDSPQRLLADLRAWGG-NPLESRRR 253 PH PF M GD LV A F PV+D + T+TYD+ L+ LRA G N L+ RR Sbjct: 168 VPHISPFPSMPQCGDALVLAHFQNPVLDRDLFTLTYDNLSALMRSLRAIGATNALQERRT 227 Query: 254 GLXVVVERLR-GFTLQALDRQRGADGKIPLSFEVIYGHAFRPV--PKTTASGEAI 305 L R R T A + R AD K+P S+EVIY A+ P P T + I Sbjct: 228 TL---TGRGRFAATATAYETLRNADNKLPSSWEVIYACAWAPTSDPMTRENNHEI 279 >NMB0271 [QR] COG0500 SAM-dependent methyltransferases Nme Neisseria meningitidis MC58 Length = 262 Score = 99.0 bits (245), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 80/281 (28%), Positives = 117/281 (41%), Gaps = 41/281 (14%) Query: 37 LRREVSARMLERLLLIKIEPQRVLDAGCGEGADIAALQKRFSDAQVVGLDGAFNMVALAR 96 + R ++ +RL L++ P+ +L AG + L KR+ A D + +A Sbjct: 10 VHRHLAEHTDQRLTLVRNAPKHILLAGADADISRSLLAKRYPQAVFEEYDSRADFLA--- 66 Query: 97 EHQLAAQSAVNRLLNKWLPAANPGGGASLACADFAQLPFAP---NALDMVWSNLALHWHP 153 +A R W G G C Q P AP DM+WSNL L Sbjct: 67 ------AAAAARKGGFW--QRFTGKGVVQHC----QSPIAPLPEACADMLWSNLGLLAAE 114 Query: 154 QPDRVFAEWRRVLRVEGLLMFSCFGPDTFKELRTAFEAVDADPHSLPFVDMHDFGDMLVN 213 Q V W R L+ +GLL F+CFG DT EL+ + + S F DMHD GDML Sbjct: 115 QILPVLHNWARALKTDGLLFFTCFGRDTLAELKCRLKENGIESRSALFPDMHDLGDMLAE 174 Query: 214 AGFSTPVMDMEAITVTYDSPQRLLADL------RAWGGNPLESRRRGLXVVVERLRGFTL 267 GF PV D + + Y + AD+ RA N + R + + ER Sbjct: 175 NGFYDPVTDTAKLVLDYKKAETFWADMDTLGVWRAMAWNDENAARSCVGTIFER------ 228 Query: 268 QALDRQRGADGKIPLSFEVIYGHAFRPVPKTTASGEAIIRF 308 +G + ++ E +YGHA + + GE +++F Sbjct: 229 ---------EGGLGITLETVYGHAVKKL--MLPQGENVVQF 258 >VC1114 [QR] COG0500 SAM-dependent methyltransferases Vch Vibrio cholerae Length = 312 Score = 97.8 bits (242), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 117/253 (46%), Gaps = 24/253 (9%) Query: 37 LRREVSARMLERLLLIKIEPQRVLDAGCGEGADIAALQKRFSDAQVVGLDGAFNMVALAR 96 +R+V R+L+++ ++ RVLD GCG G A L++R AQVV D + M+ A+ Sbjct: 80 FQRDVGLRLLQKMPSC-LKGLRVLDLGCGTGYFSALLRER--GAQVVCADISHAMLEQAK 136 Query: 97 EHQLAAQSAVNRLLNKWLPAANPGGGASLACADFAQLPFAPNALDMVWSNLALHWHPQPD 156 + R ++ G S AD QLPFA DMV+S+LAL W Sbjct: 137 Q----------RCGDE---------GMSYQLADAEQLPFASACFDMVFSSLALQWCEDLS 177 Query: 157 RVFAEWRRVLRVEGLLMFSCFGPDTFKELRTAFEAVDADPHSLPFVDMHDFGDMLVNAGF 216 +E RRVL+ G S + EL A+ +VD H F+ ++ L AG Sbjct: 178 LPLSEIRRVLKPHGQAFLSTLLDGSLFELEQAWRSVDHHRHINQFISINQVKIALAQAGC 237 Query: 217 STPVMDMEAITVTYDSPQRLLADLRAWGGNPLESRRRGLXVVVERLRGFTLQALDRQRGA 276 S +D+ AITV Y++ L+ DL+ G N + R GL + R A R Sbjct: 238 SQHHLDLAAITVWYEAAFMLMRDLKGIGANHVSGRSTGL--ISRRTLAKVELAYQSFRNQ 295 Query: 277 DGKIPLSFEVIYG 289 G +P +++V G Sbjct: 296 QGLVPATYQVCLG 308 >NMA2215 [QR] COG0500 SAM-dependent methyltransferases NmA Neisseria meningitidis Z2491 Length = 198 Score = 95.1 bits (235), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 59/187 (31%), Positives = 84/187 (44%), Gaps = 26/187 (13%) Query: 131 AQLPFAP---NALDMVWSNLALHWHPQPDRVFAEWRRVLRVEGLLMFSCFGPDTFKELRT 187 Q P AP DM+WSNL L V W R L+ +GLL F+CFG DT EL+ Sbjct: 25 CQSPTAPLPEACADMLWSNLGLLAAESIVPVLQNWARALKTDGLLFFTCFGRDTLAELKC 84 Query: 188 AFEAVDADPHSLPFVDMHDFGDMLVNAGFSTPVMDMEAITVTYDSPQRLLADL------R 241 + + S+ F DMHD GDML GF PV D + + Y + AD+ R Sbjct: 85 RLKENGIESRSVMFPDMHDLGDMLAENGFYDPVTDTAKLVLDYKKAETFWADMDTLGIWR 144 Query: 242 AWGGNPLESRRRGLXVVVERLRGFTLQALDRQRGADGKIPLSFEVIYGHAFRPVPKTTAS 301 A N + R + + ER +G + ++ E +YGHA + + Sbjct: 145 AMAWNDENAARSCVGTIFER---------------EGGLGITLETVYGHAVKKL--MLPQ 187 Query: 302 GEAIIRF 308 GE +++F Sbjct: 188 GENVVQF 194