BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0500.p         (301 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc3157 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto...   446   e-125
CAC0151 [QR] COG0500 SAM-dependent methyltransferases Cac Clostr...   130   5e-30
FN0778 [QR] COG0500 SAM-dependent methyltransferases Fnu Fusobac...   124   3e-28
MK0845 [QR] COG0500 SAM-dependent methyltransferases Mka Methano...    65   3e-10

>RSc3157 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia
           solanacearum
          Length = 278

 Score =  446 bits (1146), Expect = e-125,   Method: Compositional matrix adjust.
 Identities = 216/271 (79%), Positives = 239/271 (88%), Gaps = 3/271 (1%)

Query: 31  EIRPGQSVELLKELHILTRDGKLNQDSRRKLKQVYHLYQFIEPLLQEIRNTHPDVSVVDH 90
           EIRP QS+ELLKELHILTRDGK+NQDSRRKLKQVYHL+QFIEPLL +++     VS+VDH
Sbjct: 7   EIRPNQSIELLKELHILTRDGKMNQDSRRKLKQVYHLFQFIEPLLDDVQKAKGHVSLVDH 66

Query: 91  GAGKSYLGFILYDLFFKALEGN--SRIYGIETREELVQKSTALAKRLGFPGMSFLNLSVA 148
           GAGKSYLGFILYDLFFK   G+  S IYGIETRE LV KST LA RLGF GMSFLN+SVA
Sbjct: 67  GAGKSYLGFILYDLFFKEQPGDGASHIYGIETREALVAKSTELAARLGFKGMSFLNVSVA 126

Query: 149 DSIGSTALPEQIDVVTALHACDTATDDAIHFALKKHAQFIVLVPCCQAEVASVLNRNKGA 208
           +SI S  LP  +DVVTALHAC+TATDDAI FAL+KHAQ+IVLVPCCQAEVA VL RNKG 
Sbjct: 127 ESITSERLPPAVDVVTALHACNTATDDAIRFALEKHAQYIVLVPCCQAEVAGVLRRNKGK 186

Query: 209 SLGRTSLTELWRHPLHTREFGSQVTNVLRCLQLEAHGYQVSVTELVGWEHSMKNELIIAR 268
           SLG  +LTE+WRHPLHTREFGSQVTNVLRCLQLEAHGYQVSVTELVGWEHSMKNELI+A+
Sbjct: 187 SLG-NALTEIWRHPLHTREFGSQVTNVLRCLQLEAHGYQVSVTELVGWEHSMKNELIVAQ 245

Query: 269 YKDLPRKRPTERLQDVLQSLGLEEMGERFFS 299
           YKDLPR+RPTERL +VL +LGLEE+ ERFF+
Sbjct: 246 YKDLPRRRPTERLAEVLSTLGLEELRERFFA 276


>CAC0151 [QR] COG0500 SAM-dependent methyltransferases Cac Clostridium
           acetobutylicum
          Length = 386

 Score =  130 bits (326), Expect = 5e-30,   Method: Compositional matrix adjust.
 Identities = 78/238 (32%), Positives = 124/238 (52%), Gaps = 17/238 (7%)

Query: 32  IRPGQSVELLKELHILTRDGKLNQDSRRKLKQVYHLYQFIEPLLQEI-RNTHPDVSVVDH 90
           I+ G + +LLK + I+T+D K+  D  RK  Q+ H  + I+  L  I RN H  ++++D 
Sbjct: 130 IKIGPANDLLKAIDIMTKDNKVKNDKIRKYNQIDHFIELIDSTLDSISRNKH--ITILDC 187

Query: 91  GAGKSYLGFILYDLFFKALEGNSRIYGIETREELVQKSTALAKRLGFPGMSFLNLSVADS 150
           G GKSYL F L     +  +      GI+  E ++QKS ++A+ LG+  M F  + + D 
Sbjct: 188 GCGKSYLTFALNYYLTEVKKVKCSFIGIDISEAVIQKSKSIAQTLGYRNMDFYAMDIHD- 246

Query: 151 IGSTALPE-QIDVVTALHACDTATDDAIHFALKKHAQFIVLVPCCQAEVASVLNRNKGAS 209
                 P+ +I++V +LHACDTATD A+   ++  +  I+ VPCC  E+ S         
Sbjct: 247 ----YKPDRKINMVISLHACDTATDMALALGIRLESDAIIAVPCCHKEMLS--------Q 294

Query: 210 LGRTSLTELWRHPLHTREFGSQVTNVLRCLQLEAHGYQVSVTELVGWEHSMKNELIIA 267
                  ++ +H +    F   +T+ +R L LEA GY V+  E +    + KN LI A
Sbjct: 295 YSYEPFKDILKHGIFKARFADVLTDGMRSLMLEAKGYDVTPVEYISPLETPKNLLIRA 352


>FN0778 [QR] COG0500 SAM-dependent methyltransferases Fnu Fusobacterium
           nucleatum
          Length = 412

 Score =  124 bits (310), Expect = 3e-28,   Method: Compositional matrix adjust.
 Identities = 85/289 (29%), Positives = 150/289 (51%), Gaps = 36/289 (12%)

Query: 32  IRPGQSVELLKELHILTRDGKLNQDSRRKLKQVYHLYQFIEPLLQEIR-----NTHPDVS 86
           +  G  ++ L EL +++ +GK+ + S  K KQ+    +FI+ ++ E++     N H  ++
Sbjct: 127 LNEGDKIDFLIELGLMSVEGKILKSSYNKFKQINKYLEFIDDVIVELKTKKLINNH--IN 184

Query: 87  VVDHGAGKSYLGFILY--------DLFFKALEGNSRIYGIETREELVQKSTALAKRLGFP 138
           ++D G GKSYL F LY        DL F        I G++ ++++++    LA++L + 
Sbjct: 185 ILDFGCGKSYLTFALYYYLKNYRKDLSF-------SIVGLDLKKDVIEFCNKLAQKLSYE 237

Query: 139 GMSFLNLSVADSIGSTALPEQIDVVTALHACDTATDDAIHFALKKHAQFIVLVPCCQAEV 198
            + FLN ++ D        +++D+V +LHAC+ ATD ++  AL  +A+ I+ VPCC  E 
Sbjct: 238 NLEFLNGNIKD----YDRAKEVDLVFSLHACNNATDYSLEKALSLNAKAILAVPCCHHEF 293

Query: 199 ASVLNRNKGASLGRTSLTELWRHPLHTREFGSQVTNVLRCLQLEAHGYQVSVTELVGWEH 258
              + +NK +    T L  +  + +   +F S  T+  R L LE  GY+  + E +  EH
Sbjct: 294 FEKIQKNKDSKFYDT-LKIIADNGIVLDKFASLATDSFRSLTLELCGYKTKMIEFIDMEH 352

Query: 259 SMKNELIIA---RYKDLPR--KRPTERLQDVLQSLG----LEEMGERFF 298
           + KN LI A   R  +L    K   +    + + LG    LEE+ +++F
Sbjct: 353 TPKNILIKAIKSRSSNLKENLKEKLKEYNSLKKFLGIQPLLEELTKKYF 401


>MK0845 [QR] COG0500 SAM-dependent methyltransferases Mka Methanopyrus
           kandleri AV19
          Length = 229

 Score = 64.7 bits (156), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 17/200 (8%)

Query: 54  NQDSRRKLKQVYHLYQFIEPLLQEIRNTHPDVSVVDHGAGKSYLGFILYDLFFKALEGNS 113
            +D+ RK KQV  +   +   L+      P  +VVD G G+  L   L          + 
Sbjct: 25  GRDAWRKKKQVETILTLLCSRLK------PGDTVVDCGCGRGTLTTAL-----AVSSPSC 73

Query: 114 RIYGIETREELVQKSTALAKRLGFPGMSFLNLSVAD--SIGSTALPEQIDVVTALHACDT 171
            + G + +E   +  T L + +   G+  L   V D        LP+  DV+  LH C T
Sbjct: 74  DVLGFDIKE--FETWTELERYVESVGLDNLEFEVNDLHETAKYGLPDDPDVIVGLHLCGT 131

Query: 172 ATDDAIHFALKKHAQFIVLVPCCQAEVA-SVLNRNKGASLGRTSLTELWRHPLHTREFGS 230
            TD  +  A+   A F+++VPCC    +  V+    G   G   + E+ +    + E+  
Sbjct: 132 LTDRLLKLAVNSDAHFVLVVPCCYGRASPRVIVEELGVDEGIERVREVLKRAESSVEYQL 191

Query: 231 QVTNVLRCLQLEAHGYQVSV 250
           +V   +R   LE HGYQV V
Sbjct: 192 EVCR-MRGKFLEEHGYQVHV 210