BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0483.p (441 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1982 [L] COG0863 DNA modification methylase Rso Ralstonia sol... 387 e-107 RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 179 1e-44 STM3386 [L] COG0863 DNA modification methylase Sty Salmonella ty... 135 2e-31 all4411 [L] COG0863 DNA modification methylase Nos Nostoc sp. PC... 133 1e-30 HP1367 [L] COG0863 DNA modification methylase Hpy Helicobacter p... 132 1e-30 >RSc1982 [L] COG0863 DNA modification methylase Rso Ralstonia solanacearum Length = 270 Score = 387 bits (995), Expect = e-107, Method: Compositional matrix adjust. Identities = 174/244 (71%), Positives = 209/244 (85%) Query: 5 DRVFCEDALDGLARIPDGEIDLLIADPPYGLGKDYGNDSDKLDNDAYLAWTEQWIDVALP 64 D +F ED + G+ R+ DG +DL+IADPPYGLGKDYGNDSDKL +AYLAW+E+WI+ LP Sbjct: 7 DGIFNEDCIAGVGRLADGSVDLVIADPPYGLGKDYGNDSDKLSGEAYLAWSERWIEAVLP 66 Query: 65 KLKPNGSLYIFLTWRYSPEIFVMLKRRMTMLNEIVWDRRVPSMGGSTRKYSSVHDTIGFF 124 KL NGSLY+F TW+Y+PE+FVMLKRR++M+NEI+WDRRVPSMGGSTRK+SSVHD IGFF Sbjct: 67 KLARNGSLYLFCTWQYAPELFVMLKRRLSMINEIIWDRRVPSMGGSTRKFSSVHDNIGFF 126 Query: 125 ARAKDYYFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYNPKDVWSVSRLHREHKERAD 184 A ++DYYFD+DA+RIPYDA+TKKARSR F G KWLE+GYNPKDVWSVSRLHR+ ERA+ Sbjct: 127 AASRDYYFDVDAVRIPYDAETKKARSRKRFEGKKWLEVGYNPKDVWSVSRLHRQDPERAE 186 Query: 185 HPTQKPLEIVERMIKASCPPGGVVLDPFMGSGTTAVAARRCGRQFVGFELNPAYCAVGGX 244 HPTQKPLE+VERM+ ASCPPGG+VLDPF+GSGTTA A R GR+F GFE+N YC V Sbjct: 187 HPTQKPLELVERMVLASCPPGGLVLDPFLGSGTTAAACARLGRRFAGFEINAEYCRVARE 246 Query: 245 SISA 248 ++A Sbjct: 247 RVAA 250 >RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Rso Ralstonia solanacearum Length = 374 Score = 179 bits (454), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 96/149 (64%), Positives = 117/149 (78%) Query: 260 PMSKSLVERIIRADVRALSAYPVPDAAGFVKLDAMENPYTLPQALRDELGQRLSAVTLNR 319 P L+ RI+R DVRA+ AY VPDA+G VKLDAMENPY LP LRD LG+RL+ V LNR Sbjct: 9 PSLDDLLGRIVRDDVRAMGAYHVPDASGMVKLDAMENPYHLPAMLRDALGKRLAEVALNR 68 Query: 320 YPVPSYTLLKEKLCRHMGVPTGFDVLLGNGSDELISILSVACAQAGAKVLAPEPGFVMYA 379 YPVP+ LK +L R M VP G DVLLGNGSDE+IS++++A A+ GA VLAP PGFVMYA Sbjct: 69 YPVPTADALKAQLKRVMRVPAGADVLLGNGSDEIISLIAIAAAKPGATVLAPVPGFVMYA 128 Query: 380 VSAKFAGLEYIGVPLKTDFTLDRDAMLAA 408 +SA+ GL+++GVPL+ D TLDR+AMLAA Sbjct: 129 MSAQLMGLKFVGVPLRADLTLDREAMLAA 157 >STM3386 [L] COG0863 DNA modification methylase Sty Salmonella typhimurium LT2 Length = 294 Score = 135 bits (340), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 92/283 (32%), Positives = 142/283 (50%), Gaps = 15/283 (5%) Query: 6 RVFCEDALDGLARIPDGEIDLLIADPPYGLGKDYGNDSDKLDNDAYLAWTEQWIDVALPK 65 ++ DAL L ++P IDL+ ADPPY +GKD+ + D ++LAW + ID Sbjct: 16 KIIHGDALTELKKLPSESIDLIFADPPYNIGKDFDGMVESWDEASFLAWLYECIDECHRV 75 Query: 66 LKPNGSLYIFLTWRYSPEIFVMLKRRMTMLNEIVWDRRVPSMGGSTRKY-SSVHDTIGFF 124 LK +G++YI + P I + + T+ + IVW S G +KY S+++ I Sbjct: 76 LKKHGTMYIMNSTENMPYIDLKCRTLFTIKSRIVWS--YDSSGVQAKKYFGSMYEPILMM 133 Query: 125 ARA-KDYYFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYN----PKDVWSVSRLHREH 179 + K Y F+ DAI + +T R++ K YN P +VWS R+ Sbjct: 134 VKNPKSYTFNRDAILV----ETTTGAKRALIDYRKNPPQPYNQKKVPGNVWSFPRVRYLM 189 Query: 180 KERADHPTQKPLEIVERMIKASCPPGGVVLDPFMGSGTTAVAARRCGRQFVGFELNPAYC 239 E +HPTQKP +++R+I AS P VLDPF GS TT A GR+F+G ELN Y Sbjct: 190 DEYENHPTQKPSALLKRIILASSNPSDTVLDPFAGSFTTGAVAAASGRKFIGIELNNEYV 249 Query: 240 AVGGXSISA---WPTLTLFRHRPPMSKSLVERIIRADVRALSA 279 +G +S + L + + +++L ++ + ALS+ Sbjct: 250 KMGLRRLSVTSHYSENELAKVKKRKTQNLSKKQRNVGINALSS 292 >all4411 [L] COG0863 DNA modification methylase Nos Nostoc sp. PCC 7120 Length = 295 Score = 133 bits (334), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 79/266 (29%), Positives = 137/266 (51%), Gaps = 12/266 (4%) Query: 7 VFCEDALDGLA-RIPDGEIDLLIADPPYGLGKDYGNDSDKLDNDA-YLAWTEQWIDVALP 64 +F DAL+ L+ IP +DL+ DPPY +GK + N DK +++ Y W +W+D + Sbjct: 12 LFHGDALNILSSNIPSESVDLIFIDPPYNIGKHFSNFHDKWESEEEYANWAYKWLDECIR 71 Query: 65 KLKPNGSLYIFLTWRYSPEIFVMLKRRMTMLNEIVWDRRVPSMGGSTRKYSSVHDTIGFF 124 LK +G++Y+ + + P + L++++T+L+ IVW + T+ + S+++ I Sbjct: 72 VLKSHGTIYVMTSTQAMPYFDIYLRQKLTILSRIVWHYDSSGVQA-TKYFGSMYEPILHC 130 Query: 125 ARAK-DYYFDLDAIRIPYDAQTKKARSRSIFVGAKWLEMGYN----PKDVWSVSRLHREH 179 + K +Y F+ + I+I + K R + K + YN P +VW SR+ Sbjct: 131 VKNKSNYIFNSEEIKI----EAKTGAQRKLIDYRKAVPAPYNTEKVPGNVWYFSRVRYRM 186 Query: 180 KERADHPTQKPLEIVERMIKASCPPGGVVLDPFMGSGTTAVAARRCGRQFVGFELNPAYC 239 E +HP+QKP ++ER+I +S +VLDPF G+ T A A+R GR+ + E Y Sbjct: 187 PEYENHPSQKPESLIERIILSSSNEDSLVLDPFAGTFTVASVAKRLGRKSISIESQEEYL 246 Query: 240 AVGGXSISAWPTLTLFRHRPPMSKSL 265 +G + W + PP+ + Sbjct: 247 KIGLRRVLGWEEYKGEQLSPPIKTHI 272 >HP1367 [L] COG0863 DNA modification methylase Hpy Helicobacter pylori 26695 Length = 260 Score = 132 bits (333), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 86/250 (34%), Positives = 135/250 (54%), Gaps = 23/250 (9%) Query: 5 DRVFCEDALDGLARIPDGEIDLLIADPPYGLGKDYGNDSDKLDNDAYLAWTEQWIDVALP 64 ++++ ED L ++ D +DL I DPPY L K DS K D + +L ++ WID LP Sbjct: 4 NKIYIEDVFTFLDKLEDKSVDLAIIDPPYNL-KIASWDSFKND-EEFLTFSYAWIDKMLP 61 Query: 65 KLKPNGSLYIFLTWRYSPEIFV--MLKRRMTMLNEIVWDRRVPSMGGSTRKYSSVHDTIG 122 KLK GS YIF T ++ +F+ + +++ LN I W ++ + ++Y+ ++I Sbjct: 62 KLKDTGSFYIFNT-PFNCALFLAYLHHKKVHFLNFITWVKK-DGFANAKKRYNHAQESIL 119 Query: 123 FFA-RAKDYYFDLDAIRIPYDA--QTKKARSRSIFVGAK-WLEMGYNPK-----DVWSVS 173 F++ K+Y F+ D IRI Y++ + K A+S+ I K W NPK DVW ++ Sbjct: 120 FYSMHKKNYTFNADEIRIAYESAERIKHAQSKGILKNNKRWFP---NPKGKLCLDVWEIT 176 Query: 174 RLHREHKERAD-----HPTQKPLEIVERMIKASCPPGGVVLDPFMGSGTTAVAARRCGRQ 228 KE+ HP+ KP ++ERMIKAS ++LD F GSG T++ A+ R Sbjct: 177 SQRHVEKEKGKILKPKHPSIKPKALIERMIKASSHKNDLILDLFSGSGMTSLVAKSLERN 236 Query: 229 FVGFELNPAY 238 F+G E + Y Sbjct: 237 FIGCESHAEY 246