BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0480.p (198 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2950 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Rso ... 337 1e-92 PA5143 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Pae P... 333 2e-91 NMB1583 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nme ... 311 5e-85 NMA1772 [E] COG0131 Imidazoleglycerol-phosphate dehydratase NmA ... 311 5e-85 all4390 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nos ... 248 5e-66 >RSc2950 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Rso Ralstonia solanacearum Length = 196 Score = 337 bits (864), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 159/194 (81%), Positives = 179/194 (92%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGRQKLDTGVPFLDHMLDQIARHGLIDLDIEAKGDLHI 64 R AEV RNT+ETQIRVA++LDGTG+Q L+TGVPFLDHMLDQIARHG++DLD+ A GD HI Sbjct: 3 RRAEVTRNTSETQIRVALDLDGTGKQTLNTGVPFLDHMLDQIARHGMVDLDVTATGDTHI 62 Query: 65 DAHHTVEDVGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVEDVGITLGQA AKAIGDKKGI RYGH+YVPLDEALSRVVIDFSGRPGLE+H+PF Sbjct: 63 DDHHTVEDVGITLGQAVAKAIGDKKGIVRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPF 122 Query: 125 TRSMIGGFDVDLTSEFFHGFVNHAQVTLHVDNLRGINAHHQCETVFKAFGRALRMAIELD 184 TR+ +G FDVDL+ EFF GFVNHA VTLH+DNLRG+NAHHQ ETVFKAFGRALRMA+E+D Sbjct: 123 TRARVGSFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQIETVFKAFGRALRMAVEID 182 Query: 185 PRSAGTIPSTKGSL 198 PR+AGTIPSTKG+L Sbjct: 183 PRAAGTIPSTKGAL 196 >PA5143 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Pae Pseudomonas aeruginosa Length = 197 Score = 333 bits (853), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 160/194 (82%), Positives = 174/194 (89%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGRQKLDTGVPFLDHMLDQIARHGLIDLDIEAKGDLHI 64 R A V R+T ETQI+V+I+LDGTG+ + DTGVPFLDHM+DQIARHGLIDLDIE KGDLHI Sbjct: 4 RKASVARDTLETQIKVSIDLDGTGKARFDTGVPFLDHMMDQIARHGLIDLDIECKGDLHI 63 Query: 65 DAHHTVEDVGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVED+GITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGL+ H+PF Sbjct: 64 DDHHTVEDIGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLQMHVPF 123 Query: 125 TRSMIGGFDVDLTSEFFHGFVNHAQVTLHVDNLRGINAHHQCETVFKAFGRALRMAIELD 184 TR+ +GGFDVDL EFF GFVNHAQVTLH+DNLRG N HHQ ETVFKAFGRALRMAIELD Sbjct: 124 TRASVGGFDVDLFMEFFQGFVNHAQVTLHIDNLRGHNTHHQIETVFKAFGRALRMAIELD 183 Query: 185 PRSAGTIPSTKGSL 198 R AG +PSTKG L Sbjct: 184 ERMAGQMPSTKGCL 197 >NMB1583 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nme Neisseria meningitidis MC58 Length = 305 Score = 311 bits (797), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 146/194 (75%), Positives = 167/194 (86%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGRQKLDTGVPFLDHMLDQIARHGLIDLDIEAKGDLHI 64 R+ V RNT ETQI V+INLDG+G+ +LDTGVPFL+HM+DQIARHG+ID+DI KGDLHI Sbjct: 110 RSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHI 169 Query: 65 DAHHTVEDVGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHT ED+GITLGQA +A+GDKKGIRRYGH+YVPLDEALSRVVID SGRPGL Y+I F Sbjct: 170 DDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEF 229 Query: 125 TRSMIGGFDVDLTSEFFHGFVNHAQVTLHVDNLRGINAHHQCETVFKAFGRALRMAIELD 184 TR++IG FDVDL EFFHG VNH+ +TLH+DNL G NAHHQ ETVFKAFGRALRMA+E D Sbjct: 230 TRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHD 289 Query: 185 PRSAGTIPSTKGSL 198 PR AG PSTKG+L Sbjct: 290 PRMAGQTPSTKGTL 303 >NMA1772 [E] COG0131 Imidazoleglycerol-phosphate dehydratase NmA Neisseria meningitidis Z2491 Length = 305 Score = 311 bits (797), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 146/194 (75%), Positives = 167/194 (86%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGRQKLDTGVPFLDHMLDQIARHGLIDLDIEAKGDLHI 64 R+ V RNT ETQI V+INLDG+G+ +LDTGVPFL+HM+DQIARHG+ID+DI KGDLHI Sbjct: 110 RSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHI 169 Query: 65 DAHHTVEDVGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHT ED+GITLGQA +A+GDKKGIRRYGH+YVPLDEALSRVVID SGRPGL Y+I F Sbjct: 170 DDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEF 229 Query: 125 TRSMIGGFDVDLTSEFFHGFVNHAQVTLHVDNLRGINAHHQCETVFKAFGRALRMAIELD 184 TR++IG FDVDL EFFHG VNH+ +TLH+DNL G NAHHQ ETVFKAFGRALRMA+E D Sbjct: 230 TRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHD 289 Query: 185 PRSAGTIPSTKGSL 198 PR AG PSTKG+L Sbjct: 290 PRMAGQTPSTKGTL 303 >all4390 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nos Nostoc sp. PCC 7120 Length = 209 Score = 248 bits (634), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 122/197 (61%), Positives = 144/197 (73%) Query: 2 STPRTAEVVRNTNETQIRVAINLDGTGRQKLDTGVPFLDHMLDQIARHGLIDLDIEAKGD 61 S PR A V R T ET ++V +NLDGTG K TG+PFLDHML QI+ HGLIDLD++AKGD Sbjct: 13 SVPRIASVHRITGETNVQVTVNLDGTGICKAATGIPFLDHMLHQISSHGLIDLDVQAKGD 72 Query: 62 LHIDAHHTVEDVGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYH 121 ID HHT EDVGITLGQA AKA+GD+KGI R+G+ PLDEAL +V +DFSGRP L Y Sbjct: 73 WEIDDHHTNEDVGITLGQALAKALGDRKGIVRFGNFLAPLDEALVQVALDFSGRPHLSYG 132 Query: 122 IPFTRSMIGGFDVDLTSEFFHGFVNHAQVTLHVDNLRGINAHHQCETVFKAFGRALRMAI 181 + +G +D L EFF VNH+Q+TLH+ L GIN+HH E FKAF RA RMAI Sbjct: 133 LQIPTERVGTYDTQLVREFFVALVNHSQMTLHIRQLDGINSHHIIEATFKAFARAARMAI 192 Query: 182 ELDPRSAGTIPSTKGSL 198 E+DPR AGTIPS+KG L Sbjct: 193 EVDPRRAGTIPSSKGVL 209