BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0476.p         (153 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc2945 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Rso Ralsto...   223   2e-58
PA5066 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Pae Pseudom...   168   4e-42
NMA0837 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase NmA Neisse...   144   7e-35
NMB0627 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Nme Neisse...   142   3e-34
slr0608_1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Syn Syne...   134   8e-32

>RSc2945 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Rso Ralstonia
           solanacearum
          Length = 140

 Score =  223 bits (567), Expect = 2e-58,   Method: Compositional matrix adjust.
 Identities = 105/135 (77%), Positives = 117/135 (86%)

Query: 3   ISAKWLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKKLW 62
           +S KWLNKVKWD+ GLVPVI QE GSNDVLMFA+MNREAL +TV+TGEAV+WSRSRK+LW
Sbjct: 1   MSRKWLNKVKWDDHGLVPVIVQEQGSNDVLMFAFMNREALQKTVETGEAVFWSRSRKRLW 60

Query: 63  HKGEESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQTV 122
           HKGEESGH Q+VHEIRLDCDEDVVLL+V QV GIACHTGRH+CFFQKFEG AE G+W TV
Sbjct: 61  HKGEESGHIQQVHEIRLDCDEDVVLLRVTQVGGIACHTGRHACFFQKFEGTAEDGDWHTV 120

Query: 123 EPVLKDEAAPEKEKP 137
           EPVLK+       KP
Sbjct: 121 EPVLKNPDDIYAGKP 135


>PA5066 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Pae Pseudomonas
           aeruginosa
          Length = 134

 Score =  168 bits (425), Expect = 4e-42,   Method: Compositional matrix adjust.
 Identities = 80/125 (64%), Positives = 94/125 (75%), Gaps = 4/125 (3%)

Query: 7   WLNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKKLWHKGE 66
           WL+++ W+  GLVP IAQ+  +  VLM AWMNREALA T     A+YWSRSR KLW KGE
Sbjct: 4   WLDEIHWNADGLVPAIAQDHETGRVLMMAWMNREALALTASENRAIYWSRSRGKLWRKGE 63

Query: 67  ESGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQTVEPVL 126
           ESGH QK+HE+RLDCD DVV+L VEQV GIACHTGR SCF++ F    E G W+TV+PVL
Sbjct: 64  ESGHVQKLHELRLDCDADVVILMVEQVGGIACHTGRESCFYRVF----ENGAWKTVDPVL 119

Query: 127 KDEAA 131
           KD  A
Sbjct: 120 KDPDA 124


>NMA0837 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase NmA Neisseria
           meningitidis Z2491
          Length = 131

 Score =  144 bits (363), Expect = 7e-35,   Method: Compositional matrix adjust.
 Identities = 70/122 (57%), Positives = 88/122 (72%), Gaps = 4/122 (3%)

Query: 8   LNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKKLWHKGEE 67
           L  VK+DE GLV  IAQ+  +  +LM AWMN EAL +TV+TG A Y+SRSR+K W KGEE
Sbjct: 6   LEAVKFDEKGLVCAIAQDAETKRILMVAWMNAEALQKTVETGFAHYYSRSRQKQWMKGEE 65

Query: 68  SGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQTVEPVLK 127
           SGH QKV E+RLDCD D +++ + Q  GIACHTGR SCF++ + G    G W+T + VLK
Sbjct: 66  SGHTQKVRELRLDCDGDAIVMLIAQNGGIACHTGRESCFYKVWRG----GAWETADAVLK 121

Query: 128 DE 129
           DE
Sbjct: 122 DE 123


>NMB0627 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Nme Neisseria
           meningitidis MC58
          Length = 131

 Score =  142 bits (358), Expect = 3e-34,   Method: Compositional matrix adjust.
 Identities = 69/122 (56%), Positives = 88/122 (72%), Gaps = 4/122 (3%)

Query: 8   LNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKKLWHKGEE 67
           L  VK+DE GLV  IAQ+  +  +LM AWMN EAL +TV+TG A Y+SRSR+K W KGEE
Sbjct: 6   LEAVKFDEKGLVCAIAQDAETKRILMVAWMNAEALQKTVETGFAHYYSRSRQKQWMKGEE 65

Query: 68  SGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQKFEGNAETGEWQTVEPVLK 127
           SGH QKV  +RLDCD D +++ + Q  GIACHTGR SCF++ + G+A    W+T + VLK
Sbjct: 66  SGHTQKVRALRLDCDGDAIVMLIAQNGGIACHTGRESCFYKVWRGSA----WETADAVLK 121

Query: 128 DE 129
           DE
Sbjct: 122 DE 123


>slr0608_1 [E] COG0139 Phosphoribosyl-AMP cyclohydrolase Syn Synechocystis
          Length = 140

 Score =  134 bits (337), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 59/101 (58%), Positives = 74/101 (73%)

Query: 8   LNKVKWDEVGLVPVIAQEVGSNDVLMFAWMNREALARTVQTGEAVYWSRSRKKLWHKGEE 67
           L+K+++++ GLVP IAQ+     VLM AWMN  ALA+T+ TG+  YWSRSR++LWHKG  
Sbjct: 29  LDKIRYNDQGLVPAIAQDYLDGTVLMLAWMNEAALAKTLATGQVWYWSRSRQELWHKGAT 88

Query: 68  SGHFQKVHEIRLDCDEDVVLLKVEQVAGIACHTGRHSCFFQ 108
           SGHFQK+  IR DCD D +LL +EQ   IACHTG  SCF Q
Sbjct: 89  SGHFQKLLGIRYDCDSDALLLTIEQKGDIACHTGERSCFHQ 129