BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0389.p (425 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3063 [T] COG0642 Signal transduction histidine kinase Rso Ral... 234 2e-61 PA1798 [T] COG0642 Signal transduction histidine kinase Pae Pseu... 229 1e-59 STM1471 [T] COG0642 Signal transduction histidine kinase Sty Sal... 189 7e-48 YPO2309 [T] COG0642 Signal transduction histidine kinase Ype Yer... 188 2e-47 rstB [T] COG0642 Signal transduction histidine kinase Eco Escher... 187 5e-47 >RSc3063 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 433 Score = 234 bits (598), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 157/429 (36%), Positives = 220/429 (51%), Gaps = 8/429 (1%) Query: 1 LYLVIAALVVASILV--VNYGFPHLFAGQFAKAVRAGFNGESFMLNRLLSGRSQADQEAL 58 L L + LV +I V +++ LF + R G G F+L L + Sbjct: 6 LKLSLMMLVAGAIAVQALSWSAGRLFHDTLTQGQREGRKGYVFLLREYLDRFPGEARATA 65 Query: 59 LAQLRAAAPERYSR-PVQTLEQLPPSVREQLAQYPVGWELTGSKCCVVYVRLDDGGLV-- 115 + +L A E + T+ L R LA G + + Y+ L DG ++ Sbjct: 66 IQRLNNNATELFDMVEPDTVADLSTEQRRDLAD---GKLVVMTNRMDYYLPLRDGTVLHA 122 Query: 116 RVQSLEELPMVEVVAYVLVFSTILAAVCIWLIPHWRDLEKLRLAAARFGGGRLDARVGLS 175 R + + ++++A+ L+ L + W WRDL L AA FGGG L R L Sbjct: 123 RFEDIGYYTAIKIIAFCLIAIATLLPILFWSWLLWRDLRALEEAARGFGGGMLSTRAHLR 182 Query: 176 GRSSIRQLSSHFDRMADRIGKLIHAQRDMVNAVSHELRTPLSRLEFGLDILQHHAPDTAT 235 S++ L+ F+ MA+RI I QR+M+N +SHEL+TP++RLEFG+ +LQ P+ Sbjct: 183 RGSNVHALARQFNDMAERIQGSIQHQREMMNGISHELKTPIARLEFGIALLQSPVPEDQR 242 Query: 236 ENRILGLRKDVEELEALVAELLTLGMLEHDRQGVFTETVALPEFLRDTCGVTAEALALGK 295 + R LR DV EL+ LV ELL L LE + V + E+L A+ +A + Sbjct: 243 KARFDALRSDVRELDELVTELLALSRLEQGATHLVLMRVTVGEWLDSVVANIADDVADRQ 302 Query: 296 LELRCSVDGQLATVVTEARTLARAYSNLVRNAAQHANSVVRVRAEMAAPDAWTLVVEDDG 355 L L D A V + R +ARA NL+RNA ++A + VRAE + L VEDDG Sbjct: 303 LTLAVHADFAPAHHVCDPRLVARALLNLIRNAMRYARQAITVRAEAGTYGSLCLTVEDDG 362 Query: 356 AGIPEAERERVFESFYRLDQSRDRATGGYGLGLSIVKKIVARHGGSISVGGSELGGAMFI 415 GIP AER RVFE FYRLD SRDR TGG+GLGL+IV++I HGG + + GGA F+ Sbjct: 363 PGIPAAERARVFEPFYRLDASRDRHTGGFGLGLAIVRRIALVHGGEVRLDTGGSGGARFV 422 Query: 416 MRLPLRQLP 424 + LP LP Sbjct: 423 LLLPAMPLP 431 >PA1798 [T] COG0642 Signal transduction histidine kinase Pae Pseudomonas aeruginosa Length = 428 Score = 229 bits (584), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 132/293 (45%), Positives = 176/293 (60%), Gaps = 6/293 (2%) Query: 124 PMVEVVAYVLVFSTILAAVCIWLIPHWRDLEKLRLAAARFGGGRLDARVGLSGRSSIRQL 183 P+ V+AY+L+ + A+ +W+ PHWRDLE LRLAA RFG G L +R + RS IR L Sbjct: 132 PLFTVLAYILLGVLVGIALLVWVRPHWRDLETLRLAAQRFGDGDLSSRTRIFRRSDIRTL 191 Query: 184 SSHFDRMADRIGKLIHAQRDMVNAVSHELRTPLSRLEFGLDILQHHAPDTATENRILGLR 243 + HF++MADRI LI QR++ NAVSHELRTP+SRL F L+ L + I +R Sbjct: 192 AQHFNQMADRIESLISNQRELTNAVSHELRTPISRLSFELEQLNKQVDAEVRHDLIEDMR 251 Query: 244 KDVEELEALVAELLTLGMLEHDRQGVFTETVALPEFLRDTCG-VTAEALALGKLELRCSV 302 D+ ELE +V+ELLT LEH G E V +L V EA A G + C + Sbjct: 252 ADLGELEEMVSELLTYARLEHGNVGSHREIVDAASWLDSVVADVALEAEAAG---VTCEI 308 Query: 303 DG-QLATVVTEARTLARAYSNLVRNAAQHANSVVRVRAEMAAPDAWTLVVEDDGAGIPEA 361 Q+ + E R +ARA NL+RNA +HA+S V + A + D+ + V DDG GIP Sbjct: 309 SACQVEQIRIEPRFMARAVINLLRNAIRHAHSRVEI-ALLDQGDSCQIRVNDDGPGIPAD 367 Query: 362 ERERVFESFYRLDQSRDRATGGYGLGLSIVKKIVARHGGSISVGGSELGGAMF 414 R+++FE F RLD SRDR+TGG+GLGL+IV ++ HGG + GGA F Sbjct: 368 ARQKIFEPFSRLDDSRDRSTGGFGLGLAIVHRVAQWHGGYAEALETPQGGASF 420 >STM1471 [T] COG0642 Signal transduction histidine kinase Sty Salmonella typhimurium LT2 Length = 433 Score = 189 bits (481), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 115/310 (37%), Positives = 173/310 (55%), Gaps = 16/310 (5%) Query: 120 LEELPMVEVVAYVLVFSTILAAVCIWLIPHWRDLEKLRLAAARFGGGRLDARVGLSGRSS 179 L ++ ++++ L+ ++ V IW+ PHW+++ +L AA RFG G L R+ SS Sbjct: 131 LHQMRLLDIALMALIAFSLAFPVFIWMRPHWQEMLRLESAAQRFGEGHLTERLHFDNGSS 190 Query: 180 IRQLSSHFDRMADRIGKLIHAQRDMVNAVSHELRTPLSRLEFGLDILQHHAPDTATENRI 239 +L F++MAD I LI +++ +++ ++HELRTPL RL + L++ ++ P + Sbjct: 191 FERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSENLTPPESQ---- 246 Query: 240 LGLRKDVEELEALVAELLTLGMLEHDRQGVFTETVALPEFL----RDTCGVTAEALALGK 295 L +D+ +LEAL+ ELLT L+ + + LP +L +D VT E Sbjct: 247 -ALNRDIGQLEALIEELLTYARLDRPQNELMLTEPDLPAWLLAHLQDVQSVTPER----A 301 Query: 296 LELRCSVDGQLATVVTEARTLARAYSNLVRNAAQHANSVVRVRAEMAAPDAWTLVVEDDG 355 + L V G + + R ++R NL+ NA +++++ V+V + A TL+VEDDG Sbjct: 302 VNLVTCVIGDYGAL--DMRLMSRVLDNLLNNALRYSHTTVQVSLLLDGSQA-TLIVEDDG 358 Query: 356 AGIPEAERERVFESFYRLDQSRDRATGGYGLGLSIVKKIVARHGGSISVGGSELGGAMFI 415 GI RERVFE F RLD SRDRATGG GLGL+IV I GGS+ SELGGA F Sbjct: 359 PGIEADARERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVVCDESELGGAKFS 418 Query: 416 MRLPLRQLPP 425 R P+ P Sbjct: 419 FRWPVWHAMP 428 >YPO2309 [T] COG0642 Signal transduction histidine kinase Ype Yersinia pestis Length = 425 Score = 188 bits (477), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 114/284 (40%), Positives = 156/284 (54%), Gaps = 8/284 (2%) Query: 142 VCIWLIPHWRDLEKLRLAAARFGGGRLDARVGLSGRSSIRQLSSHFDRMADRIGKLIHAQ 201 V +W+ PHW+DL KL AA R G G LD R SS+ +L F++MAD I LI ++ Sbjct: 144 VFLWMRPHWKDLLKLENAAQRLGSGHLDERTHFDPTSSLSRLGVAFNQMADNINTLIVSK 203 Query: 202 RDMVNAVSHELRTPLSRLEFGLDILQHHAPDTATENRILGLRKDVEELEALVAELLTLGM 261 + +++ ++HELRTPL RL + L + D TE+ L D+ +LEAL+ ELLT Sbjct: 204 KLLIDGIAHELRTPLVRLRYRLAM-----SDNLTESEQQALHHDIGQLEALIDELLTYAR 258 Query: 262 LEHDRQGVFTETVALPEFLRDTCGVTAEALALGKLELRCSVDGQLATVVTEARTLARAYS 321 L+ + + E + LP +L ++EL G V + R + R Sbjct: 259 LDRPQVSLNLEPIDLPAWLTTKIMDIRSIHQEREIELDIPHRGDFGAV--DLRLMERVLD 316 Query: 322 NLVRNAAQHANSVVRVRAEMAAPDAWTLVVEDDGAGIPEAERERVFESFYRLDQSRDRAT 381 NLV NA ++++ +R+ +A L VEDDG GIP ER R+FE F RLD SRDRAT Sbjct: 317 NLVNNALRYSHQRLRIGLWFDGDNA-CLQVEDDGPGIPPEERTRIFEPFVRLDPSRDRAT 375 Query: 382 GGYGLGLSIVKKIVARHGGSISVGGSELGGAMFIMRLPLRQLPP 425 GG GLGL+IV I + GSISV S LGGA F P++ P Sbjct: 376 GGCGLGLAIVHSIALAYQGSISVNTSPLGGASFRFSWPIKTHLP 419 >rstB [T] COG0642 Signal transduction histidine kinase Eco Escherichia coli K12 Length = 433 Score = 187 bits (474), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 109/314 (34%), Positives = 167/314 (53%), Gaps = 8/314 (2%) Query: 112 GGLVRVQSLEELPMVEVVAYVLVFSTILAAVCIWLIPHWRDLEKLRLAAARFGGGRLDAR 171 G + + L ++ ++++ + ++ V IW+ PHW+D+ KL AA RFG G L+ R Sbjct: 123 GPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPHWQDMLKLEAAAQRFGDGHLNER 182 Query: 172 VGLSGRSSIRQLSSHFDRMADRIGKLIHAQRDMVNAVSHELRTPLSRLEFGLDILQHHAP 231 + SS +L F++MAD I LI +++ +++ ++HELRTPL RL + L++ Sbjct: 183 IHFDEGSSFERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEM-----S 237 Query: 232 DTATENRILGLRKDVEELEALVAELLTLGMLEHDRQGVFTETVALPEFLRDTCGVTAEAL 291 D + L +D+ +LEAL+ ELLT L+ + + LP +L Sbjct: 238 DNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELHLSEPDLPLWLSTHLADIQAVT 297 Query: 292 ALGKLELRCSVDGQLATVVTEARTLARAYSNLVRNAAQHANSVVRVRAEMAAPDAWTLVV 351 + ++ V G A + + R + R NL+ NA ++ +S V ++ A TL+V Sbjct: 298 PDKTVRIKTLVQGHYAAL--DMRLMERVLDNLLNNALRYCHSTVETSLLLSGNRA-TLIV 354 Query: 352 EDDGAGIPEAERERVFESFYRLDQSRDRATGGYGLGLSIVKKIVARHGGSISVGGSELGG 411 EDDG GI RE +FE F RLD SRDR+TGG GLGL+IV I GG+++ SELGG Sbjct: 355 EDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLAIVHSIALAMGGTVNCDTSELGG 414 Query: 412 AMFIMRLPLRQLPP 425 A F PL P Sbjct: 415 ARFSFSWPLWHNIP 428