BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0341.p (493 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2197 [J] COG1530 Ribonucleases G and E Rso Ralstonia solanace... 736 0.0 NMA0672 [J] COG1530 Ribonucleases G and E NmA Neisseria meningit... 570 e-162 NMB1791 [J] COG1530 Ribonucleases G and E Nme Neisseria meningit... 568 e-162 PA4477 [J] COG1530 Ribonucleases G and E Pae Pseudomonas aeruginosa 541 e-153 VC0419 [J] COG1530 Ribonucleases G and E Vch Vibrio cholerae 515 e-146 >RSc2197 [J] COG1530 Ribonucleases G and E Rso Ralstonia solanacearum Length = 489 Score = 736 bits (1901), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/494 (73%), Positives = 422/494 (85%), Gaps = 6/494 (1%) Query: 1 MNEDILINITPQETRVALILQGAVQELHIERTLSRGLAGNVYLGKVVRVLPGMQSAFIDI 60 M+EDIL+NITPQETRVA++ Q AVQELHIERTL+RGL GN+YLGKVVRVLPGMQSAFIDI Sbjct: 1 MSEDILVNITPQETRVAIVQQAAVQELHIERTLTRGLVGNIYLGKVVRVLPGMQSAFIDI 60 Query: 61 GLERAAFLHVADIWEAKPHDGQHGQHGQNVPQIPIEKLLFDGQTITVQVIKDPIGTKGAR 120 GLERAAFLHVADIW + + P + IEK LF+GQ +TVQVIKDPIGTKGAR Sbjct: 61 GLERAAFLHVADIWHPR-----EAKDAPAAPHVAIEKTLFEGQALTVQVIKDPIGTKGAR 115 Query: 121 LSTQISIAGRMLVYLPQDKHIGISQRIENEAEREQLRSKVQGLLPPEEKGGFIIRTMAED 180 LSTQISIAGR LVYLPQD HIGISQ+I NE +RE LR +V ++P +E+GGFI+RT+AE+ Sbjct: 116 LSTQISIAGRTLVYLPQDPHIGISQKIGNETDREALRQRVTRMVPADERGGFIVRTIAEE 175 Query: 181 ASDADLQMDVEYLRKTWASIIAQTKTKPAPTLMYQDLSLAQRVLRDFVSDDTSNIQVDSR 240 A+D +L DV YLRK WA+I T PAP+++YQDL+LAQRVLRDFV+DDT +IQ+DSR Sbjct: 176 ATDEELANDVAYLRKIWATIRHNATTLPAPSILYQDLNLAQRVLRDFVTDDTRSIQIDSR 235 Query: 241 ENFQMLQEFGTLYTPSVLPKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQ 300 EN+Q L EF YTP+V+ +L HY GERP+FDLY +E E+ERAL RRVDLKSGGYL++DQ Sbjct: 236 ENYQKLIEFAQEYTPAVVERLTHYTGERPIFDLYNIEAEVERALSRRVDLKSGGYLMIDQ 295 Query: 301 TEAMTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMENLEH 360 TEAMTTIDVNTG +V RNFDDTIFKTNLEAAH IARQLRLRNLGGIII+DFIDME+ EH Sbjct: 296 TEAMTTIDVNTGGYVGARNFDDTIFKTNLEAAHTIARQLRLRNLGGIIIIDFIDMESGEH 355 Query: 361 RTAVLSELNKALHRDRTKISVSGFSALGLVEMTRKRTRESLAHILCETCPACKGKGQVKT 420 R AVL+EL +AL RDRT+I+V+ FS LGLVEMTRKRTRESLAH+LCE CP C+GKGQVKT Sbjct: 356 RDAVLAELRRALARDRTRITVNSFSQLGLVEMTRKRTRESLAHVLCEQCPVCQGKGQVKT 415 Query: 421 SRTVCYEILREVLREAKQFNPREFRILAAQVVVDMFLEEESQHLAMLGDFIKKPISLQVQ 480 RTVCY+ILRE++RE++QFNPREFRILA+Q V+D+FLEEESQHLAMLGDFI KPISLQV+ Sbjct: 416 PRTVCYDILREIMRESRQFNPREFRILASQSVIDLFLEEESQHLAMLGDFIGKPISLQVE 475 Query: 481 T-DYQQEQYDIILM 493 + QEQYDIILM Sbjct: 476 SAAASQEQYDIILM 489 >NMA0672 [J] COG1530 Ribonucleases G and E NmA Neisseria meningitidis Z2491 Length = 497 Score = 570 bits (1470), Expect = e-162, Method: Compositional matrix adjust. Identities = 295/493 (59%), Positives = 367/493 (74%), Gaps = 13/493 (2%) Query: 3 EDILINITPQETRVALILQGAVQELHIERTLSRGLAGNVYLGKVVRVLPGMQSAFIDIGL 62 E IL+NITPQETRVA++ + + ELHIER L GN+YLG V RVLPGMQSAFIDIGL Sbjct: 16 ETILVNITPQETRVAVLEENNICELHIERNSEHSLVGNIYLGVVRRVLPGMQSAFIDIGL 75 Query: 63 ERAAFLHVADIWEAK--PHDGQHGQHGQNVPQIPIEKLLFDGQTITVQVIKDPIGTKGAR 120 ERAAFLH+ D+ E + P + Q IE +LF+GQ++ VQVIKDPI TKGAR Sbjct: 76 ERAAFLHIVDVLEQRRNPEETQR-----------IEHMLFEGQSVLVQVIKDPINTKGAR 124 Query: 121 LSTQISIAGRMLVYLPQDKHIGISQRIENEAEREQLRSKVQGLLPPEEKGGFIIRTMAED 180 LSTQIS+AGR LV+LPQ+ HIG+SQRIE++AER LR ++ LLP G+IIRT AE+ Sbjct: 125 LSTQISLAGRFLVHLPQEDHIGVSQRIEDDAERSSLRERLDKLLPENACRGYIIRTNAEN 184 Query: 181 ASDADLQMDVEYLRKTWASIIAQTKTKPAPTLMYQDLSLAQRVLRDFVSDDTSNIQVDSR 240 A+D LQ D++YL K W I Q K +P TL+YQDL L+ RVLRD V DT I VDS Sbjct: 185 ATDEQLQSDIDYLTKVWEHIQEQAKIRPPETLLYQDLPLSLRVLRDMVGCDTQKILVDST 244 Query: 241 ENFQMLQEFGTLYTPSVLPKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQ 300 N + F Y L ++ ++GERPLF+ + VE+EI RAL RV+L G YLI++ Sbjct: 245 VNHGRMTRFAEQYVHGALGRIELFKGERPLFETHNVEQEISRALQPRVNLNFGSYLIIES 304 Query: 301 TEAMTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMENLEH 360 TEAMTTIDVNTG FV RNFD+TIF+TNLEA H IAR+LRLRNLGGIII+DFIDM H Sbjct: 305 TEAMTTIDVNTGGFVGARNFDETIFRTNLEACHTIARELRLRNLGGIIIIDFIDMAQESH 364 Query: 361 RTAVLSELNKALHRDRTKISVSGFSALGLVEMTRKRTRESLAHILCETCPACKGKGQVKT 420 R AVL EL KAL DRT++++ GF++LGLVE+TRKR+RE+L +LCE CP+C+G+G++KT Sbjct: 365 REAVLQELAKALAFDRTRVTLHGFTSLGLVELTRKRSRENLNQVLCEPCPSCQGRGRLKT 424 Query: 421 SRTVCYEILREVLREAKQFNPREFRILAAQVVVDMFLEEESQHLAMLGDFIKKPISLQVQ 480 +TVCYEI RE++REA++++ FRILAA V+D+FL+EESQ LAML DFI KPISL V+ Sbjct: 425 PQTVCYEIQREIVREARRYDAESFRILAAPNVIDLFLDEESQSLAMLIDFIGKPISLAVE 484 Query: 481 TDYQQEQYDIILM 493 T Y QEQYDI+LM Sbjct: 485 TAYTQEQYDIVLM 497 >NMB1791 [J] COG1530 Ribonucleases G and E Nme Neisseria meningitidis MC58 Length = 509 Score = 568 bits (1465), Expect = e-162, Method: Compositional matrix adjust. Identities = 294/493 (59%), Positives = 366/493 (74%), Gaps = 13/493 (2%) Query: 3 EDILINITPQETRVALILQGAVQELHIERTLSRGLAGNVYLGKVVRVLPGMQSAFIDIGL 62 E IL+NITP ETRVA++ + + ELHIER L GN+YLG V RVLPGMQSAFIDIGL Sbjct: 28 ETILVNITPAETRVAVLEENNICELHIERNSEHSLVGNIYLGVVRRVLPGMQSAFIDIGL 87 Query: 63 ERAAFLHVADIWEAK--PHDGQHGQHGQNVPQIPIEKLLFDGQTITVQVIKDPIGTKGAR 120 ERAAFLH+ D+ E + P + Q IE +LF+GQ++ VQVIKDPI TKGAR Sbjct: 88 ERAAFLHIVDVLEQRRNPEETQR-----------IEHMLFEGQSVLVQVIKDPINTKGAR 136 Query: 121 LSTQISIAGRMLVYLPQDKHIGISQRIENEAEREQLRSKVQGLLPPEEKGGFIIRTMAED 180 LSTQIS+AGR LV+LPQ+ HIG+SQRIE++AER LR ++ LLP G+IIRT AE+ Sbjct: 137 LSTQISLAGRFLVHLPQEDHIGVSQRIEDDAERSSLRERLDKLLPENACRGYIIRTNAEN 196 Query: 181 ASDADLQMDVEYLRKTWASIIAQTKTKPAPTLMYQDLSLAQRVLRDFVSDDTSNIQVDSR 240 A+D LQ D++YL K W I Q K +P TL+YQDL L+ RVLRD V DT I VDS Sbjct: 197 ATDEQLQSDIDYLTKVWEHIQEQAKIRPPETLLYQDLPLSLRVLRDMVGCDTQKILVDST 256 Query: 241 ENFQMLQEFGTLYTPSVLPKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVDQ 300 N + F Y L ++ ++GERPLF+ + VE+EI RAL RV+L G YLI++ Sbjct: 257 VNHGRMTRFAEQYVHGALGRIELFKGERPLFETHNVEQEISRALQPRVNLNFGSYLIIES 316 Query: 301 TEAMTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMENLEH 360 TEAMTTIDVNTG FV RNFD+TIF+TNLEA H IAR+LRLRNLGGIII+DFIDM H Sbjct: 317 TEAMTTIDVNTGGFVGARNFDETIFRTNLEACHTIARELRLRNLGGIIIIDFIDMAQESH 376 Query: 361 RTAVLSELNKALHRDRTKISVSGFSALGLVEMTRKRTRESLAHILCETCPACKGKGQVKT 420 R AVL EL KAL DRT++++ GF++LGLVE+TRKR+RE+L +LCE CP+C+G+G++KT Sbjct: 377 REAVLQELAKALAFDRTRVTLHGFTSLGLVELTRKRSRENLNQVLCEPCPSCQGRGRLKT 436 Query: 421 SRTVCYEILREVLREAKQFNPREFRILAAQVVVDMFLEEESQHLAMLGDFIKKPISLQVQ 480 +TVCYEI RE++REA++++ FRILAA V+D+FL+EESQ LAML DFI KPISL V+ Sbjct: 437 PQTVCYEIQREIVREARRYDAESFRILAAPNVIDLFLDEESQSLAMLIDFIGKPISLAVE 496 Query: 481 TDYQQEQYDIILM 493 T Y QEQYDI+LM Sbjct: 497 TAYTQEQYDIVLM 509 >PA4477 [J] COG1530 Ribonucleases G and E Pae Pseudomonas aeruginosa Length = 485 Score = 541 bits (1393), Expect = e-153, Method: Compositional matrix adjust. Identities = 282/496 (56%), Positives = 359/496 (72%), Gaps = 14/496 (2%) Query: 1 MNEDILINITPQETRVALILQGAVQELHIERTLSRGLAGNVYLGKVVRVLPGMQSAFIDI 60 M+E+ILINITP E+RVA++ G +QE+H+ERT RG+ GN+Y G+VVRVLPGMQ+AF+DI Sbjct: 1 MSEEILINITPMESRVAVVENGVLQEVHVERTQRRGIVGNIYKGRVVRVLPGMQAAFVDI 60 Query: 61 GLERAAFLHVADIWEAKPHDGQHGQHGQNVPQIPIEKLLFDGQTITVQVIKDPIGTKGAR 120 GLERAAF+H A+I + G V I L+ +GQ + VQV KDPIGTKGAR Sbjct: 61 GLERAAFIHAAEI---------SNREGSAVESIS--ALVHEGQALVVQVTKDPIGTKGAR 109 Query: 121 LSTQISIAGRMLVYLPQDKHIGISQRIENEAEREQLRSKVQGLLPPEE---KGGFIIRTM 177 L+T +SI R LVY+P+ H+GIS RIE+E ERE+L+ V + E +GGFI+RT Sbjct: 110 LTTHLSIPSRYLVYMPRTSHVGISLRIEDEVERERLKKVVADCVAAEGIEGQGGFILRTA 169 Query: 178 AEDASDADLQMDVEYLRKTWASIIAQTKTKPAPTLMYQDLSLAQRVLRDFVSDDTSNIQV 237 AE A + ++ D+ YLR+ W I AQ +T AP+++Y+DLSLA R LRD V+ I++ Sbjct: 170 AEGAGEDEILADIRYLRRLWDQIAAQIQTVGAPSVIYEDLSLAIRTLRDLVNPRIEKIRI 229 Query: 238 DSRENFQMLQEFGTLYTPSVLPKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLI 297 DSRENFQ + F P + +L HY GERP+FDLYGVE+EI++AL R+V LKSGGYLI Sbjct: 230 DSRENFQKITSFVEELMPEISDRLEHYPGERPIFDLYGVEDEIQKALERKVLLKSGGYLI 289 Query: 298 VDQTEAMTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMEN 357 VD TEAMTTIDVNTG+FV RN ++TIFKTNLEAA AIARQLRLRNLGGIII+DFIDME+ Sbjct: 290 VDPTEAMTTIDVNTGAFVGHRNLEETIFKTNLEAATAIARQLRLRNLGGIIIIDFIDMED 349 Query: 358 LEHRTAVLSELNKALHRDRTKISVSGFSALGLVEMTRKRTRESLAHILCETCPACKGKGQ 417 EHR VL L K L RD K ++ G + LGLV+MTRKRTRESL ILCE CP C+G+G Sbjct: 350 EEHRRQVLRTLEKQLERDHAKTNIIGITELGLVQMTRKRTRESLVQILCEPCPCCQGRGM 409 Query: 418 VKTSRTVCYEILREVLREAKQFNPREFRILAAQVVVDMFLEEESQHLAMLGDFIKKPISL 477 +KT+ T CYEI RE+LREA+ + + +LA Q VVD L+EES ++A L FI + I Sbjct: 410 LKTAETTCYEIFREILREARAYQADSYLVLANQKVVDRLLDEESGNVADLEAFIGRTIKF 469 Query: 478 QVQTDYQQEQYDIILM 493 QV+ Y QEQYD++L+ Sbjct: 470 QVEAMYSQEQYDVVLL 485 >VC0419 [J] COG1530 Ribonucleases G and E Vch Vibrio cholerae Length = 489 Score = 515 bits (1327), Expect = e-146, Method: Compositional matrix adjust. Identities = 260/494 (52%), Positives = 356/494 (72%), Gaps = 6/494 (1%) Query: 1 MNEDILINITPQETRVALILQGAVQELHIERTLSRGLAGNVYLGKVVRVLPGMQSAFIDI 60 M+ ++L+N+TP ETRVA+I G +QE+HIER RG+ GN+Y GKV RVLPGMQ+AF+DI Sbjct: 1 MSAELLLNVTPSETRVAMIEGGILQEIHIEREAKRGIVGNIYKGKVSRVLPGMQAAFVDI 60 Query: 61 GLERAAFLHVADIWEAKPHDGQHGQHGQNVPQI-PIEKLLFDGQTITVQVIKDPIGTKGA 119 GL++AAFLH +DI PH + + Q+ I +L+ GQ I VQV+KDP+GTKGA Sbjct: 61 GLDKAAFLHASDIV---PHTECVAESEKQQFQVRDISELVRQGQDIVVQVVKDPLGTKGA 117 Query: 120 RLSTQISIAGRMLVYLPQDKHIGISQRIENEAEREQLRSKVQGLLPPEEKGGFIIRTMAE 179 RL+T I++ R LV++P H+G+SQRIE+EAERE+L+ V +E GGFIIRT AE Sbjct: 118 RLTTDITLPSRYLVFMPGASHVGVSQRIESEAERERLKKIVSHYC--DEHGGFIIRTAAE 175 Query: 180 DASDADLQMDVEYLRKTWASIIAQTKTKPAPTLMYQDLSLAQRVLRDFVSDDTSNIQVDS 239 A++ +L D +L++ W+ +I + +++Y +L LAQR+LRDFV + + I +DS Sbjct: 176 GANEKELTQDAAFLKRLWSKVIERRSKYKNRSMLYGELGLAQRILRDFVGTELTKILIDS 235 Query: 240 RENFQMLQEFGTLYTPSVLPKLMHYRGERPLFDLYGVEEEIERALGRRVDLKSGGYLIVD 299 R+ F+ L+EF + Y P + KL Y G++P+FD+Y E EI+R+L R+V+LKSGGYLI+D Sbjct: 236 RQEFENLKEFTSEYVPELTAKLELYHGDKPIFDMYDTENEIQRSLERKVELKSGGYLIID 295 Query: 300 QTEAMTTIDVNTGSFVNGRNFDDTIFKTNLEAAHAIARQLRLRNLGGIIILDFIDMENLE 359 QTEAMTTID+NTG+FV RN ++TIF TN+EA AIARQLRLRNLGGIII+DFIDM + E Sbjct: 296 QTEAMTTIDINTGAFVGRRNLEETIFNTNIEATQAIARQLRLRNLGGIIIIDFIDMASDE 355 Query: 360 HRTAVLSELNKALHRDRTKISVSGFSALGLVEMTRKRTRESLAHILCETCPACKGKGQVK 419 HR VL+ L AL +DR K +++GF+ LGLVEMTRKRTRES+ H+LC TCP C+G+G VK Sbjct: 356 HRKRVLTSLETALMKDRVKTNINGFTQLGLVEMTRKRTRESIEHVLCSTCPTCEGRGSVK 415 Query: 420 TSRTVCYEILREVLREAKQFNPREFRILAAQVVVDMFLEEESQHLAMLGDFIKKPISLQV 479 T TVC+EILRE+ R + ++ +F + A+ V D EES LA L FI K + +Q Sbjct: 416 TVETVCFEILREITRVNRAYDADKFVVYASPAVADTLQGEESHALAELEVFIGKEVRIQA 475 Query: 480 QTDYQQEQYDIILM 493 + Y QEQ+D+++M Sbjct: 476 EPLYNQEQFDVVMM 489