BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0319.p (465 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA... 347 4e-95 PA5283 [KE] COG1167 Transcriptional regulators containing a DNA-... 329 1e-89 AGc398 [KE] COG1167 Transcriptional regulators containing a DNA-... 315 1e-85 BMEI0169 [KE] COG1167 Transcriptional regulators containing a DN... 315 1e-85 RSp1057 [KE] COG1167 Transcriptional regulators containing a DNA... 308 2e-83 >RSc0989 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 490 Score = 347 bits (889), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 180/456 (39%), Positives = 280/456 (61%), Gaps = 5/456 (1%) Query: 9 SVRMSLVEQIVEQLRKLIDKGTLRSGTKMTSIRLFAQQQAVSVHTVAEAYERLVALGYFE 68 S +M+LV+Q+ E R ID+ R+G +M SIR AQ++++S TV EAYERLVA GY E Sbjct: 30 SAQMTLVDQLTEWARMRIDERVFRAGMRMPSIRQLAQEKSISRFTVVEAYERLVAQGYLE 89 Query: 69 SRPRSGFFIK-RAHTAEQKRDPTQSFAKAFDHLWQLRSHLINADGLLNVTSGKLPTDWMD 127 SR SGF++K R ++ + A+ D W LR+ +A+ G LP W+D Sbjct: 90 SRRGSGFYVKERQAPLPEEPPAPPASARKIDVAWLLRNMFHSAEPRKAPGIGFLPNGWLD 149 Query: 128 ADMVRASLKSVAAKIDSAMLQYGDPHGYLPLRSLLQTRLSDLGIHTQSDQILLTGGASQA 187 +++ +L+++ + + L +G P G+LPLR LQTRL++L I + DQI++T G +Q+ Sbjct: 150 GELIANALRALGRQNGNQFLAWGTPQGFLPLRQQLQTRLAELEIGARPDQIVMTSGITQS 209 Query: 188 MDLIIRYLLRTGDKVLVDDPGYFNLFSNLQMQGIEPLPVRRNHDGPDLDMLENLAQLHRP 247 +DLI R ++ GD VLV DP +F +F QG + + V +GPDL LE L Q+ RP Sbjct: 210 LDLIARQYVQPGDTVLVGDPAWFLMFGRFAAQGAQVIGVPYTTEGPDLVALEGLVQVRRP 269 Query: 248 RMMFTQSILQTPTGSTISAGNAYRLLRLAEQYDFRIVENDVYADML--GEPVPRIAALDQ 305 +++ S+L PTG+++SA A++LLRLAEQY F IVE+D+Y D+ G P R+A+LDQ Sbjct: 270 KLLVINSVLHNPTGTSLSAAKAFQLLRLAEQYGFLIVEDDIYGDLAPPGHPATRLASLDQ 329 Query: 306 LSRVLYVGSFSKTLSVSARVGYVAAAAADIRDLANMKMITSITSAQLAEKFVFHALTEGL 365 L RV+Y+GSFSKTL+ + RVG++A ++L + K++ + + ++ E+ ++ LTEG Sbjct: 330 LRRVIYLGSFSKTLAANLRVGFIACHPELAKNLTDGKLLAGLATPEINERVLYKVLTEGQ 389 Query: 366 YRRSVERLRLRLAASMAETEKALRPLGFQFFCRPLGGKFVWLRHPNFESSSDIWKLAGDA 425 YR+ VER+R RL + +++L LG + F + G F+W ++ I + + Sbjct: 390 YRKHVERVRARLDRARDGVQRSLERLGLKLFAQQGAGMFIW--ADTGRDTNAIARAGHEE 447 Query: 426 GIVIAPGKVFRSSMQDTPWFRLNVSYGTEPALLKFL 461 G V APG +F S + W R N++ T+P +L+FL Sbjct: 448 GYVFAPGSLFSPSQMPSTWMRFNIATSTDPEMLRFL 483 >PA5283 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Pae Pseudomonas aeruginosa Length = 458 Score = 329 bits (843), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 178/448 (39%), Positives = 266/448 (59%), Gaps = 6/448 (1%) Query: 14 LVEQIVEQLRKLIDKGTLRSGTKMTSIRLFAQQQAVSVHTVAEAYERLVALGYFESRPRS 73 LV+QIV + I +R+GT++ SIR A++ +S +V EAY+RLVALG ESR S Sbjct: 13 LVQQIVAGVSGWIRGNRVRAGTRIPSIRQLARENQLSQSSVIEAYDRLVALGMLESRHGS 72 Query: 74 GFFIKRAHTAEQKRDPTQSFAKAFDHLWQLRSHLINADGLLNVTSGKLPTDWMDADMVRA 133 GFF+ A A D + + ++ W + L + G +P W + + + Sbjct: 73 GFFVAEAPAATTDLD--SEWHEGAENAW---GQFSGSSTKLKLGCGWIPDSWREVEELSY 127 Query: 134 SLKSVAAKIDSAMLQYGDPHGYLPLRSLLQTRLSDLGIHTQSDQILLTGGASQAMDLIIR 193 +++ VA + + Y P G LR +Q RL + IH +QIL T GAS A+DL++R Sbjct: 128 AIRQVARSELAGLFDYSTPLGLPALRQHIQKRLRLIDIHVDPEQILTTTGASHALDLLVR 187 Query: 194 YLLRTGDKVLVDDPGYFNLFSNLQMQGIEPLPVRRNHDGPDLDMLENLAQLHRPRMMFTQ 253 LL+ GD V+V++PGY+NLF+ L+ G++ L V R GPD LE + + H+P+ +FT Sbjct: 188 TLLKPGDVVVVENPGYYNLFNLLKFHGVKMLGVPRTRHGPDTAALETILRAHKPKFLFTN 247 Query: 254 SILQTPTGSTISAGNAYRLLRLAEQYDFRIVENDVYADMLGEPVPRIAALDQLSRVLYVG 313 S+ PTG+++S A+R+L+LAEQ+DF IVE+D+YAD P R+A LD L RV+Y+ Sbjct: 248 SMYHNPTGTSLSPSVAHRVLQLAEQHDFHIVEDDIYADFQNGPSTRLATLDSLRRVIYLA 307 Query: 314 SFSKTLSVSARVGYVAAAAADIRDLANMKMITSITSAQLAEKFVFHALTEGLYRRSVERL 373 SFSKTLS S RVGY+ A IR LA++KM TSI S + AE V L G YR+ V+RL Sbjct: 308 SFSKTLSCSLRVGYLIAGPELIRRLADVKMYTSIGSQRFAECVVSTMLANGSYRKLVQRL 367 Query: 374 RLRLAASMAETEKALRPLGFQFFCRPLGGKFVWLRHPNFESSSDIWKLAGDAGIVIAPGK 433 R RL MA T + L G++ F P+GG FVW R ++ +++ +A ++++PG Sbjct: 368 RQRLTRQMAATLRVLGDNGWEVFAEPVGGMFVWARIGDY-PFAELQAVATRLDVLLSPGS 426 Query: 434 VFRSSMQDTPWFRLNVSYGTEPALLKFL 461 F +++ W R+N++Y ++P L F Sbjct: 427 GFSPEGEESDWLRINIAYASDPRALAFF 454 >AGc398 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 449 Score = 315 bits (808), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 169/444 (38%), Positives = 251/444 (56%) Query: 18 IVEQLRKLIDKGTLRSGTKMTSIRLFAQQQAVSVHTVAEAYERLVALGYFESRPRSGFFI 77 ++ +R+ I +L G ++ S+R A+ +S T+ EAY+RLVA G SRP SGFF+ Sbjct: 1 MMANIRQRITSRSLVPGARLPSVRALAKTMQLSTSTIVEAYDRLVADGTISSRPGSGFFV 60 Query: 78 KRAHTAEQKRDPTQSFAKAFDHLWQLRSHLINADGLLNVTSGKLPTDWMDADMVRASLKS 137 D +A D LW R L + L G LP WM + +R +++ Sbjct: 61 AGPLAPLSLADIEPRLDRAVDPLWVSRQALDDGSALAKPGCGWLPASWMPQEALRRAMRG 120 Query: 138 VAAKIDSAMLQYGDPHGYLPLRSLLQTRLSDLGIHTQSDQILLTGGASQAMDLIIRYLLR 197 +A D+ + YG P G LPLR LL RL++ G+ + QI+LT +QA+DL+ R+LL+ Sbjct: 121 LARADDALLTDYGSPMGLLPLRQLLSRRLAEHGVQAGASQIMLTDSGTQAIDLLCRFLLQ 180 Query: 198 TGDKVLVDDPGYFNLFSNLQMQGIEPLPVRRNHDGPDLDMLENLAQLHRPRMMFTQSILQ 257 GD V+VDDP YFN + L+ ++ + V GPDL + E + H+PR+ T S + Sbjct: 181 PGDTVVVDDPCYFNFHALLRAHRVKIVGVPYTPAGPDLPLFEQALKEHQPRLYITNSAIH 240 Query: 258 TPTGSTISAGNAYRLLRLAEQYDFRIVENDVYADMLGEPVPRIAALDQLSRVLYVGSFSK 317 PTG+ +SA +A+RLL LAEQ I+E+D++AD + PR+AA D L+RV+ +GSFSK Sbjct: 241 NPTGARLSAVSAHRLLMLAEQPGLTIIEDDIFADFETQAAPRLAAFDGLNRVVQIGSFSK 300 Query: 318 TLSVSARVGYVAAAAADIRDLANMKMITSITSAQLAEKFVFHALTEGLYRRSVERLRLRL 377 TLS S R G++AA A + L ++K+ T+ + V LT+G YR+ VE LR RL Sbjct: 301 TLSASVRCGFIAAPRAWVEALTDLKIATAFGGTHFSAALVLSLLTDGSYRKHVEALRQRL 360 Query: 378 AASMAETEKALRPLGFQFFCRPLGGKFVWLRHPNFESSSDIWKLAGDAGIVIAPGKVFRS 437 AA++ E LR +G + P G F+W R P ++D+ + A +V+APG VF S Sbjct: 361 AAAVPEAATRLRSIGCMPWIEPQAGMFLWCRLPEGTDAADVAQRALARQVVLAPGNVFSS 420 Query: 438 SMQDTPWFRLNVSYGTEPALLKFL 461 S + + R NVS P ++ L Sbjct: 421 SQNASGFMRFNVSQMVGPQVMTVL 444 >BMEI0169 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Bme Brucella melitensis Length = 484 Score = 315 bits (807), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 176/458 (38%), Positives = 252/458 (55%), Gaps = 11/458 (2%) Query: 11 RMSLVEQIVEQLRKLIDKGTLRSGTKMTSIRLFAQQQAVSVHTVAEAYERLVALGYFESR 70 RM LVE+++ +R I +L G ++ SIR A+ VS TV EAY+RLVA G +SR Sbjct: 24 RMPLVEKVMGIIRGRITAMSLAPGARLPSIRRLAETMNVSKSTVVEAYDRLVAEGIIQSR 83 Query: 71 PRSGFFIKRAHTAEQKRDPTQSFAKA------FDHLWQLRSHLINADGLLNVTSGKLPTD 124 +GF++ +E+ R P A A D W +R L L G LP Sbjct: 84 RGAGFYV-----SERARQPFSLAATAPHKDRQIDPFWVMRQSLEAESRTLKPGCGWLPDG 138 Query: 125 WMDADMVRASLKSVAAKIDSAMLQYGDPHGYLPLRSLLQTRLSDLGIHTQSDQILLTGGA 184 W+ + +R +L+++A S + YG+P G+ PLR L RL + GI +ILLT Sbjct: 139 WLPQEALRRALRTIARDDQSNLTTYGEPLGFRPLRQHLAHRLGEQGIDIAGGEILLTDSG 198 Query: 185 SQAMDLIIRYLLRTGDKVLVDDPGYFNLFSNLQMQGIEPLPVRRNHDGPDLDMLENLAQL 244 +QA+DLI RYLL+ GD VLVDDP YFN + L ++ + V H GPDLD N A Sbjct: 199 TQAIDLICRYLLQPGDTVLVDDPCYFNFQAVLLTHRVKLVGVPYTHSGPDLDAFANAATE 258 Query: 245 HRPRMMFTQSILQTPTGSTISAGNAYRLLRLAEQYDFRIVENDVYADMLGEPVPRIAALD 304 H P++ + + L PTG ++ A+RLL+LAE + +VE++++ D P P +A LD Sbjct: 259 HAPKLYISNAGLHNPTGGIMTPATAHRLLKLAEAHGITLVEDNIFGDFHPSPTPLLAELD 318 Query: 305 QLSRVLYVGSFSKTLSVSARVGYVAAAAADIRDLANMKMITSITSAQLAEKFVFHALTEG 364 RVL++GSFSKTLS +ARVGY+A I L ++K+ TS L+ + V L +G Sbjct: 319 GFERVLHIGSFSKTLSAAARVGYIAGRRDWIEGLTDLKLATSFGCNALSPQIVHALLIDG 378 Query: 365 LYRRSVERLRLRLAASMAETEKALRPLGFQFFCRPLGGKFVWLRHPNFESSSDIWKLAGD 424 YRR +E LR RLA +M T L+ G + +P GG F+W R P+ S + + A + Sbjct: 379 TYRRHIESLRTRLADAMTLTANRLKATGLDLWTKPQGGMFLWARLPDGMDSGPVARHALE 438 Query: 425 AGIVIAPGKVFRSSMQDTPWFRLNVSYGTEPALLKFLR 462 G+V+APG VF S + R NV+ +P + LR Sbjct: 439 KGVVLAPGNVFSPSCTAAGFLRFNVAQSADPYIYAVLR 476 >RSp1057 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Rso Ralstonia solanacearum Length = 471 Score = 308 bits (789), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 174/452 (38%), Positives = 251/452 (55%), Gaps = 3/452 (0%) Query: 13 SLVEQIVEQLRKLIDKGTLRSGTKMTSIRLFAQQQAVSVHTVAEAYERLVALGYFESRPR 72 +LV+QIV+ +R +D +L GT++ S+R AQ +S TVAEAY RL ALG +RPR Sbjct: 17 TLVDQIVQGIRAAVDNHSLPPGTRLPSVRKLAQAHGISTFTVAEAYTRLAALGAIVARPR 76 Query: 73 SGFFIKRAHTAEQKRDPTQSFAKAFDHLWQLRSHLINADGLLNVTSGKLPTDWMDADMVR 132 SG+ + + + A + W L + + G LP DW+D V+ Sbjct: 77 SGYLVAARAPVQPVPVAPRWEPPALNAAWLLSDVFADRSIAIKPGCGWLPNDWLDERGVQ 136 Query: 133 ASLKSVAAKIDSAMLQYGDPHGYLPLRSLLQTRLSDLGIHTQSDQILLTGGASQAMDLII 192 +++ V+ + YG P GY PL + L+ G+ + Q+LLT GA+QA+DLI+ Sbjct: 137 EAMRMVSRVSALRVAGYGHPWGYAPLGEYVAQSLALRGLPVERAQVLLTSGATQALDLIV 196 Query: 193 RYLLRTGDKVLVDDPGYFNLFSNLQMQGIEPLPVRRNHDGPDLDMLENLA---QLHRPRM 249 R L + GD V V+DP Y N+ L++ G+ + V R +G D LE + + RPR Sbjct: 197 RTLFKAGDVVAVEDPVYCNVLQVLKLAGLRVVGVPRTPEGLDTAALETVLRQDEASRPRA 256 Query: 250 MFTQSILQTPTGSTISAGNAYRLLRLAEQYDFRIVENDVYADMLGEPVPRIAALDQLSRV 309 +F ++LQ PTGS+++A NAYR+L+LAEQ+ IVE+D++ ++ P +AALD L R Sbjct: 257 LFVSTVLQNPTGSSMTAQNAYRVLQLAEQHGLWIVEDDLHRELADPAAPMLAALDGLRRT 316 Query: 310 LYVGSFSKTLSVSARVGYVAAAAADIRDLANMKMITSITSAQLAEKFVFHALTEGLYRRS 369 LYV FSKT+S S R GYV A AA R+LA KM ++TS+++ E+ V +T Y Sbjct: 317 LYVSGFSKTISPSLRAGYVVADAAITRELARTKMAVALTSSEITERIVHAFVTRPAYAEH 376 Query: 370 VERLRLRLAASMAETEKALRPLGFQFFCRPLGGKFVWLRHPNFESSSDIWKLAGDAGIVI 429 V RL RL A+ A E +R G F P G F+W R P +S + A I + Sbjct: 377 VARLNARLGAAHAGVEATMREHGAVVFDTPGRGLFLWARLPGHADASALADRAIRGNIWL 436 Query: 430 APGKVFRSSMQDTPWFRLNVSYGTEPALLKFL 461 APG+ FR +PW R NV+Y +PAL FL Sbjct: 437 APGQYFRPDDAASPWLRFNVAYSGDPALWDFL 468