BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0313.p (412 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 153 9e-37 lin2949 [GEPR] COG0477 Permeases of the major facilitator superf... 125 1e-28 Z4105 [GEPR] COG0477 Permeases of the major facilitator superfam... 125 2e-28 ECs3649 [GEPR] COG0477 Permeases of the major facilitator superf... 125 2e-28 ygcZ [GEPR] COG0477 Permeases of the major facilitator superfami... 124 5e-28 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 153 bits (386), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 119/375 (31%), Positives = 181/375 (48%), Gaps = 28/375 (7%) Query: 45 DRMAMSVSIIPITKEFALDAQAAGLVLGSFYISYALMQLAAGWLADRFGSRRVLVFCVAC 104 DR +S + I KEF L A G+V+ +F+ SYAL+QL AG LADRFG ++VL F V Sbjct: 31 DRTVLSAAAPHIQKEFHLSAVEMGVVMSAFFWSYALLQLPAGILADRFGQKKVLGFAVLW 90 Query: 105 WSVFTSMTGLAGSFFGLIVIRLLFGLGEGGFAPASTVTIAEAFPKPERARAKSLIIGASF 164 WS+ T++TGLA F L+ +R+ G+GE G P++ + FPK ERA ++ S Sbjct: 91 WSLATAVTGLATGFKSLVGLRVALGVGEAGAYPSNAGITSRWFPKQERATVAAIFDSGSK 150 Query: 165 LGSAVGTGAIAALIHAHGWRFAYHAFGLIGVAVAIVLWFAVKDSPVRPQEVRTKGLFRTL 224 LGSA+ IA L+ W+ + G +G+ +V +DSP + V L Sbjct: 151 LGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVVWALVFRDSPAEHEGVNAAELAHIQ 210 Query: 225 FG---------------KMVLKKT---MLI-FFFSNIVYVGLISWMPTFLMKTRDIDIVH 265 G K++ + M I FF N I+W+PT+L+K R + ++ Sbjct: 211 KGLPPARGADAPAMPWTKLLTHRNVWAMCIGFFMINYNSYFFITWLPTYLVKERGMGLME 270 Query: 266 VGAASAIPYLVAFAALNVVGWLLDKV-GQGR------DRLFMSIGAAMVIVFLGLMAVAT 318 +G +++P V+ GW D+V GR +LF+ IG M +GL A A Sbjct: 271 MGFMASLPLFVSMFVEVFAGWASDRVYASGRLSLTATRKLFLVIGLVMA-SSIGLAAFAQ 329 Query: 319 TLPWLLAFWTLSLVGYTAVYGTVFAIPLKHLPDESVGTASGIINFGGQVAAGIAPVVIGM 378 + + ++ G T V+A+P P +V +G+ N + + P+V G Sbjct: 330 SAVVAVILLCIAKSGTTVAASQVWALPADVAPGNTVSMVAGLQNSVSNMGGVVGPIVTGA 389 Query: 379 LVTAGKGSFNLAFAF 393 +V A GSF A F Sbjct: 390 IVGA-TGSFIPALVF 403 >lin2949 [GEPR] COG0477 Permeases of the major facilitator superfamily Lin Listeria innocua Length = 401 Score = 125 bits (315), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 103/399 (25%), Positives = 185/399 (46%), Gaps = 21/399 (5%) Query: 24 GRGQKIFVLVTLLFSWILANADRMAMSVSIIPITKEFALDAQAAGLVLGSFYISYALMQL 83 G + VL+ L + D+ + +S++ ++++ D GL+L +F++ Y L Q+ Sbjct: 6 GEKHSLMVLLVLFIGYTSVYVDKYTIGISLVTVSQDLGFDPSQKGLILSAFFLGYTLFQI 65 Query: 84 AAGWLADRFGSRRVLVFCVACWSVFTSMTGLAGSFFGLIVIRLLFG-LGEGGFAPASTVT 142 G+L +R G+R VL + +F + G S L+VIR L G G G+ P+ + Sbjct: 66 PMGYLNNRIGARPVLAISIIIVGLFLIIFGFGYSLLFLVVIRFLSGAFGHAGYPPSVSNY 125 Query: 143 IAEAFPKPERARAKSLIIGASFLGSAVGTGAIAALIHAHGWRFAYHAFGLIGVAVAIVLW 202 I+ P +R A+S ++ +S + +G IA L+ + GWR Y+ G++ + + +++ Sbjct: 126 ISLHIPLNKRGFAQSAMLASSGFAAFIGPLLIAQLLLSVGWRNTYYWIGIVVIFIGLLIL 185 Query: 203 FAVKDSPVRPQEVRTKGLFRTLFGKMVLKKTMLIFFFS----NIVYVGLISWMPTFLMKT 258 V +P + + K + F +++ K + I S N GL SW+ ++L + Sbjct: 186 LVVPKAP-KIDKSTQKEKIKVPFSELLKDKQLWILLLSALFINAANYGLTSWLASYLNEA 244 Query: 259 RDIDIVHVGAASAIPYLVAFAALNVVGWLLDKVGQGRDRL----FMSIGAAM---VIVFL 311 R I I V S++ L A + G+ + + +G++ + F +GA V +F Sbjct: 245 RGISISEVSYISSLAGLCILIAGVIGGYFISRFFKGKEPIVIFTFSVLGAFTVYGVYLFD 304 Query: 312 GLMAVATTLPWLLAFWTLSLVGYTAVYGTVFAIPLKHLPDESVGTASGIINFGGQVAAGI 371 LM L F ++ + T+ +P K + T IN GG + Sbjct: 305 QLMLSIICLCLCNIFLIMA-------FTTLMGLPHKLFKQSHIATKYAAINSGGVLGGFF 357 Query: 372 APVVIGMLVTAGKGSFNLAFAFLLAAGLGALLIALSWKS 410 AP++IG LV A S+ AF FL L + +I L+ K Sbjct: 358 APMIIGDLVNA-TNSYQSAFLFLALTFLVSGIIVLAIKK 395 >Z4105 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 450 Score = 125 bits (315), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 120/448 (26%), Positives = 196/448 (43%), Gaps = 72/448 (16%) Query: 11 ASQVQEPRPAARYGRGQKIFVLVTLLFSWILANADRMAMSVSIIPITKEFALDAQAAGLV 70 A+ E R ARY +++V L DR +S++ + K+ LD G V Sbjct: 7 AASSVEKRTNARY------WIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYV 60 Query: 71 LGSFYISYALMQLAAGWLADRFGSRRVLVFCVACWSVFTSMTGLAGSF--FGLIV----I 124 +F +Y + Q+ GWL DRFGS+RV + + WS+FT + G F FG+IV + Sbjct: 61 FSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTL 120 Query: 125 RLLFGLGEGGFAPASTVTIAEAFPKPERARAKSLIIGASFLGSAVGTGAIAALIHAHGWR 184 R L GL E P ++ +A FP ER A S+ A + + + + L H GW Sbjct: 121 RFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWS 180 Query: 185 FAYHAFGLIGVAVAIVLWFAVKDSP----------------------VRPQEVRTKGLFR 222 + G +G+A++ + W V P + Q + K F Sbjct: 181 HVFFFMGGLGIAISFI-WLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFS 239 Query: 223 TLFG--KMVLKKTMLIFFFSNIVYVG----------LISWMPTFLMKTRDIDIVHVGAAS 270 +G K +L M+I VY+G I+W P +L++ R + I+ G + Sbjct: 240 VKWGQIKQLLGSRMMIG-----VYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVA 294 Query: 271 AIPYLVAFAALNVVG-----WLLDKVGQ----GRDRLFMSIGAAMVIVFLGLMAVATTLP 321 ++P + F V+G WL+ + G + + M + +MV+VF + V Sbjct: 295 SVPAVCGFIG-GVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNV----E 349 Query: 322 WL-LAFWTLSLVGYTAVYGTVFAIPLKHLPDESVGTASGIINFGGQVAAGIAPVVIGMLV 380 W+ + F L+ G + +A+ P E G + G+ N G ++ + P+ IG +V Sbjct: 350 WMIIGFMALAFFG-KGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIV 408 Query: 381 TAGKGSFNLAFAFLLAAGLGALLIALSW 408 GSFN A L+ G+ AL+ LS+ Sbjct: 409 GT-TGSFNGA---LIYVGVHALIAVLSY 432 >ECs3649 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 450 Score = 125 bits (315), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 120/448 (26%), Positives = 196/448 (43%), Gaps = 72/448 (16%) Query: 11 ASQVQEPRPAARYGRGQKIFVLVTLLFSWILANADRMAMSVSIIPITKEFALDAQAAGLV 70 A+ E R ARY +++V L DR +S++ + K+ LD G V Sbjct: 7 AASSVEKRTNARY------WIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYV 60 Query: 71 LGSFYISYALMQLAAGWLADRFGSRRVLVFCVACWSVFTSMTGLAGSF--FGLIV----I 124 +F +Y + Q+ GWL DRFGS+RV + + WS+FT + G F FG+IV + Sbjct: 61 FSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTL 120 Query: 125 RLLFGLGEGGFAPASTVTIAEAFPKPERARAKSLIIGASFLGSAVGTGAIAALIHAHGWR 184 R L GL E P ++ +A FP ER A S+ A + + + + L H GW Sbjct: 121 RFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWS 180 Query: 185 FAYHAFGLIGVAVAIVLWFAVKDSP----------------------VRPQEVRTKGLFR 222 + G +G+A++ + W V P + Q + K F Sbjct: 181 HVFFFMGGLGIAISFI-WLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFS 239 Query: 223 TLFG--KMVLKKTMLIFFFSNIVYVG----------LISWMPTFLMKTRDIDIVHVGAAS 270 +G K +L M+I VY+G I+W P +L++ R + I+ G + Sbjct: 240 VKWGQIKQLLGSRMMIG-----VYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVA 294 Query: 271 AIPYLVAFAALNVVG-----WLLDKVGQ----GRDRLFMSIGAAMVIVFLGLMAVATTLP 321 ++P + F V+G WL+ + G + + M + +MV+VF + V Sbjct: 295 SVPAVCGFIG-GVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNV----E 349 Query: 322 WL-LAFWTLSLVGYTAVYGTVFAIPLKHLPDESVGTASGIINFGGQVAAGIAPVVIGMLV 380 W+ + F L+ G + +A+ P E G + G+ N G ++ + P+ IG +V Sbjct: 350 WMIIGFMALAFFG-KGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIV 408 Query: 381 TAGKGSFNLAFAFLLAAGLGALLIALSW 408 GSFN A L+ G+ AL+ LS+ Sbjct: 409 GT-TGSFNGA---LIYVGVHALIAVLSY 432 >ygcZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 450 Score = 124 bits (310), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 119/448 (26%), Positives = 195/448 (43%), Gaps = 72/448 (16%) Query: 11 ASQVQEPRPAARYGRGQKIFVLVTLLFSWILANADRMAMSVSIIPITKEFALDAQAAGLV 70 A+ E R ARY +++V L DR +S++ + K+ LD G V Sbjct: 7 AASSVEKRTNARY------WIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYV 60 Query: 71 LGSFYISYALMQLAAGWLADRFGSRRVLVFCVACWSVFTSMTGLAGSF--FGLIV----I 124 +F +Y + Q+ GWL DRFGS+RV + + WS+FT + G F FG+IV + Sbjct: 61 FSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTL 120 Query: 125 RLLFGLGEGGFAPASTVTIAEAFPKPERARAKSLIIGASFLGSAVGTGAIAALIHAHGWR 184 R L GL E P ++ +A FP ER A S+ A + + + + L H GW Sbjct: 121 RFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQYFATVIFAPIMGWLTHEVGWS 180 Query: 185 FAYHAFGLIGVAVAIVLWFAVKDSP----------------------VRPQEVRTKGLFR 222 + G +G+ ++ + W V P + Q + K F Sbjct: 181 HVFFFMGGLGIVISFI-WLKVIHEPNQHPGVNKKELEYIAAGGALINMDQQNTKVKVPFS 239 Query: 223 TLFG--KMVLKKTMLIFFFSNIVYVG----------LISWMPTFLMKTRDIDIVHVGAAS 270 +G K +L M+I VY+G I+W P +L++ R + I+ G + Sbjct: 240 VKWGQIKQLLGSRMMIG-----VYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVA 294 Query: 271 AIPYLVAFAALNVVG-----WLLDKVGQ----GRDRLFMSIGAAMVIVFLGLMAVATTLP 321 ++P + F V+G WL+ + G + + M + +MV+VF + V Sbjct: 295 SVPAVCGFIG-GVLGGIISDWLMRRTGSLNIARKTPIVMGMLLSMVMVFCNYVNV----E 349 Query: 322 WL-LAFWTLSLVGYTAVYGTVFAIPLKHLPDESVGTASGIINFGGQVAAGIAPVVIGMLV 380 W+ + F L+ G + +A+ P E G + G+ N G ++ + P+ IG +V Sbjct: 350 WMIIGFMALAFFG-KGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVTPIAIGYIV 408 Query: 381 TAGKGSFNLAFAFLLAAGLGALLIALSW 408 GSFN A L+ G+ AL+ LS+ Sbjct: 409 GT-TGSFNGA---LIYVGVHALIAVLSY 432