BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0296.p         (202 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSc2726 [V] COG1566 Multidrug resistance efflux pump Rso Ralston...   222   4e-58
mll0995 [V] COG1566 Multidrug resistance efflux pump Mlo Mesorhi...   165   7e-41
PA3136 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomo...   153   2e-37
RSp0440 [V] COG1566 Multidrug resistance efflux pump Rso Ralston...   149   3e-36
BMEII0793 [V] COG1566 Multidrug resistance efflux pump Bme Bruce...   149   4e-36

>RSc2726 [V] COG1566 Multidrug resistance efflux pump Rso Ralstonia
           solanacearum
          Length = 388

 Score =  222 bits (565), Expect = 4e-58,   Method: Compositional matrix adjust.
 Identities = 109/173 (63%), Positives = 131/173 (75%)

Query: 28  LEAARLRVHSIEAQVRQARAQGETARAQFDAANVNLGSTQVTASVAGRIGDKQVRVGQFV 87
           L  A L + +++AQ+RQA AQ +TARAQ   A VNL +T++ AS  GR+GD QVR GQFV
Sbjct: 203 LTKATLEIAALQAQLRQAEAQAKTARAQAAVAEVNLAATELRASTDGRVGDSQVRAGQFV 262

Query: 88  SAGTRLMTVVPSDFYVVANFKETQIGSMRTGQPVAIKVDALPGTKFKGHVESIAPGTGAQ 147
           SAGTRLM+VVP   Y+ ANFKETQ+G MR GQPV I VDA P    +GHVES++PGTGAQ
Sbjct: 263 SAGTRLMSVVPMHLYITANFKETQLGRMRIGQPVHIHVDAFPDEAIEGHVESLSPGTGAQ 322

Query: 148 FSLLPPQNATGNFTKIVQRVPVRIAVDASAEDRRIFVAGLSVTAEVDTAATER 200
           FSLLPPQNATGNF KIVQRVPVRIA+D +   + +  AG+SVT +VDT A  R
Sbjct: 323 FSLLPPQNATGNFIKIVQRVPVRIALDVTDRLKPLLAAGMSVTVDVDTLAPVR 375


>mll0995 [V] COG1566 Multidrug resistance efflux pump Mlo Mesorhizobium loti
          Length = 417

 Score =  165 bits (417), Expect = 7e-41,   Method: Compositional matrix adjust.
 Identities = 85/182 (46%), Positives = 125/182 (68%), Gaps = 2/182 (1%)

Query: 18  ASAVASRRAALEAARLRVHSIEAQVRQARAQGETARAQFDAANVNLGSTQVTASVAGRIG 77
           A+ +A  +AA+ AA +R+  +  +  +A AQ + A+A  + A +NL    +TA V G +G
Sbjct: 209 AAGLARDQAAVVAAEVRIDVLATERDKALAQVDRAQAAGEQARLNLSYATITAPVDGTVG 268

Query: 78  DKQVRVGQFVSAGTRLMTVVPSD-FYVVANFKETQIGSMRTGQPVAIKVDALPGTKFKGH 136
            + +R+GQ+V AGT+LM VVP +  YVVANFKETQ+  +R GQPV + +D  PG + +GH
Sbjct: 269 ARTLRIGQYVGAGTQLMAVVPQNAVYVVANFKETQLTYVRGGQPVRVAIDGFPGVELEGH 328

Query: 137 VESIAPGTGAQFSLLPPQNATGNFTKIVQRVPVRIAVDASAEDRRIFVAGLSVTAEVDTA 196
           V+S++P +G +F+LLPP NATGNFTKIVQR+PV+I ++   E   +  AG+SV   +DT 
Sbjct: 329 VDSLSPASGLEFALLPPDNATGNFTKIVQRIPVKIMIE-DQELGGLLRAGMSVEPTIDTK 387

Query: 197 AT 198
           AT
Sbjct: 388 AT 389


>PA3136 [V] COG1566 Multidrug resistance efflux pump Pae Pseudomonas
           aeruginosa
          Length = 355

 Score =  153 bits (387), Expect = 2e-37,   Method: Compositional matrix adjust.
 Identities = 83/201 (41%), Positives = 122/201 (60%), Gaps = 9/201 (4%)

Query: 3   ALRRPKWSAIHRWPPASA--------VASRRAALEAARLRVHSIEAQVRQARAQGETARA 54
           ALR+P + +  R    +A        +A  RA LEA R++  ++ A++++  AQ  +AR 
Sbjct: 151 ALRKPGYVSEERVTTLTADNHVARSQLAKARADLEAQRVQRDTLGAEIKRLEAQIASART 210

Query: 55  QFDAANVNLGSTQVTASVAGRIGDKQVRVGQFVSAGTRLMTVVPS-DFYVVANFKETQIG 113
           +   A +NL  T + + ++G +G +  R GQ+V  GT L+++VP  D +V ANFKETQ+G
Sbjct: 211 ELAQAEINLSRTLIHSPISGLVGQRSARNGQYVQVGTHLLSLVPDEDIWVQANFKETQVG 270

Query: 114 SMRTGQPVAIKVDALPGTKFKGHVESIAPGTGAQFSLLPPQNATGNFTKIVQRVPVRIAV 173
            MR GQ   +  DA P T   G ++S+   +GAQFSLLPP NATGNFTK+VQR+PV+I  
Sbjct: 271 RMRDGQKARLTFDAFPDTPIDGRIDSLFAASGAQFSLLPPDNATGNFTKVVQRIPVKIVF 330

Query: 174 DASAEDRRIFVAGLSVTAEVD 194
           +A          G+SV AEV+
Sbjct: 331 EADNPLHGRIRPGMSVEAEVE 351


>RSp0440 [V] COG1566 Multidrug resistance efflux pump Rso Ralstonia
           solanacearum
          Length = 363

 Score =  149 bits (377), Expect = 3e-36,   Method: Compositional matrix adjust.
 Identities = 79/175 (45%), Positives = 107/175 (61%), Gaps = 1/175 (0%)

Query: 26  AALEAARLRVHSIEAQVRQARAQGETARAQFDAANVNLGSTQVTASVAGRIGDKQVRVGQ 85
           A L +A  +   + A + +ARA   +A+A+   A +NL   +V A V+G +  +  RVG 
Sbjct: 172 AGLHSAEQQTAILRADLEKARASLLSAQAEKATAELNLSYARVIAPVSGVVAQRSARVGG 231

Query: 86  FVSAGTRLMTVVPSD-FYVVANFKETQIGSMRTGQPVAIKVDALPGTKFKGHVESIAPGT 144
           +   G  L+T+VP D  YV ANF+ETQ+  +R GQP  I VDALP  + KG VES+ P +
Sbjct: 232 YARVGQPLLTLVPLDAVYVEANFRETQLAHVRVGQPATITVDALPNVRLKGRVESLGPAS 291

Query: 145 GAQFSLLPPQNATGNFTKIVQRVPVRIAVDASAEDRRIFVAGLSVTAEVDTAATE 199
           G  FS  PP NATGNFTKIVQR+PVRI ++   ED R+   G+SV   +D  A E
Sbjct: 292 GVSFSTTPPHNATGNFTKIVQRLPVRIRIEPGQEDARLLRVGMSVRPSIDVRAQE 346


>BMEII0793 [V] COG1566 Multidrug resistance efflux pump Bme Brucella
           melitensis
          Length = 325

 Score =  149 bits (376), Expect = 4e-36,   Method: Compositional matrix adjust.
 Identities = 76/180 (42%), Positives = 116/180 (64%)

Query: 19  SAVASRRAALEAARLRVHSIEAQVRQARAQGETARAQFDAANVNLGSTQVTASVAGRIGD 78
           +AV    AAL  A+  + +I        A    A A    A ++L +T++ A   G++G+
Sbjct: 143 AAVDQAEAALAVAKEDLRTIIVAREGLNADLHNAEAAVALARIDLQNTKILAPRDGKLGE 202

Query: 79  KQVRVGQFVSAGTRLMTVVPSDFYVVANFKETQIGSMRTGQPVAIKVDALPGTKFKGHVE 138
             VR+GQ+V+AGT+L+++VP+  +++ANFKETQ+  M+ GQPV + VDAL   + KGH+E
Sbjct: 203 VGVRLGQYVTAGTQLVSLVPAVKWIMANFKETQLYGMKVGQPVTLTVDALRHAELKGHIE 262

Query: 139 SIAPGTGAQFSLLPPQNATGNFTKIVQRVPVRIAVDASAEDRRIFVAGLSVTAEVDTAAT 198
           + +P TG++FS++   NATGNFTKI QR+ VRI++D    D  +   G+SV   VDTA+T
Sbjct: 263 AFSPATGSEFSVIKSDNATGNFTKITQRLSVRISIDEGQPDAELLAPGMSVVVRVDTAST 322