BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0295.p (525 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2727 [GEPR] COG0477 Permeases of the major facilitator superf... 673 0.0 PA3137 [GEPR] COG0477 Permeases of the major facilitator superfa... 338 1e-92 mll0994 [GEPR] COG0477 Permeases of the major facilitator superf... 336 7e-92 RC0200 [GEPR] COG0477 Permeases of the major facilitator superfa... 283 6e-76 RP157 [GEPR] COG0477 Permeases of the major facilitator superfam... 281 4e-75 >RSc2727 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 511 Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/493 (71%), Positives = 417/493 (84%) Query: 33 GTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIIIIPLSSWLEKLLGL 92 GTLGA+MATLDISIVNS+LPTIQGEIGA+ TEGTWIATAYLVAEIIIIPL+ WLEKLLGL Sbjct: 19 GTLGAMMATLDISIVNSALPTIQGEIGATSTEGTWIATAYLVAEIIIIPLAGWLEKLLGL 78 Query: 93 RTLLLAAAGLFTLFSVMCGLSTTLPMMIVGRIGQGFTGGALIPTAMTIIATRLPREQQPV 152 R LLLAA GLFT FS++CG++ TLPMM++GR GQGFTGG LIPTAMTIIA RLPR QQP+ Sbjct: 79 RNLLLAATGLFTGFSMLCGVAETLPMMVIGRAGQGFTGGVLIPTAMTIIAARLPRAQQPL 138 Query: 153 GNALFGATAILGPVLGPVLGGWLTENVSWHYSFFLNVPVGIALITLLLVAVPYERPKVEL 212 G ALFG+T ILGPV GP+LGGW+T ++WHY+FF+N+P+ L LLL+ +P+ERP+ L Sbjct: 139 GTALFGSTVILGPVFGPMLGGWMTTQLNWHYAFFINLPICGVLAALLLLGMPHERPRTAL 198 Query: 213 LAEADWLGILGMALGLGGLTVVLEEGEREQWFSSPDIRWLAVVSLLGFILLAIGQWRARH 272 L EADW GI G+ALGLGG+TVVLEEG+R QWF+SP IRWLA VS LGF LL GQ RAR Sbjct: 199 LREADWAGIAGLALGLGGMTVVLEEGQRLQWFTSPAIRWLAAVSALGFGLLGWGQARARA 258 Query: 273 PVIQLRLLRDRQFGSVALMAMAVGVALYGTAYVIPQFLAGIAGYNSLQSGVIVLLSGVPM 332 PVI+L LLRDRQFG++A+MA+A +ALYGTAYVIPQFL GIAGY++LQSG IVLLSG+PM Sbjct: 259 PVIRLGLLRDRQFGAIAVMAIAASMALYGTAYVIPQFLVGIAGYDALQSGWIVLLSGLPM 318 Query: 333 ILMMPFTPLLMRTVDIRLAVGVGLLLLAASAFMETDLSPLSYGGSFVASQLMRGIGTVLA 392 I++MP PL++R +D+RLAVG GLL+LA SA++ET LSPLS G SFVASQLMRG+GTVL Sbjct: 319 IVLMPMLPLMLRWLDVRLAVGGGLLVLALSAYIETGLSPLSTGNSFVASQLMRGLGTVLT 378 Query: 393 MLFLNQAAIRSVPASQAGDAAGIYSAARNLGGSLALASIAVIQDQRLWLHSRRLEESISA 452 M+FLNQAAIRSVP SQA DA+G+Y+ RNLGGS+ALA IA +Q+QRLWLHSRR+E+++ A Sbjct: 379 MMFLNQAAIRSVPPSQASDASGLYNGLRNLGGSIALACIATLQEQRLWLHSRRIEDTLQA 438 Query: 453 NAELVQSSMATQAHLLGGPDIAIRLLGSTIQMQALTMTYADLFWLLGVAILCITPLVLFL 512 NA VQ +A QAH LG A+ + +IQ+QALTM YADLFWLL VAIL +TPLV+FL Sbjct: 439 NAAGVQDYIAGQAHALGSQAAALLSMEQSIQVQALTMAYADLFWLLTVAILLVTPLVVFL 498 Query: 513 RPLPTNAAPVAAH 525 RPLP +A PVA H Sbjct: 499 RPLPRHAGPVAGH 511 >PA3137 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 499 Score = 338 bits (868), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 191/482 (39%), Positives = 277/482 (57%) Query: 35 LGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIIIIPLSSWLEKLLGLRT 94 LGA MA LDI I NSSL IQG + A+ EG+WI+T+YLVAEII+IP+++WL +LL R Sbjct: 6 LGAFMAVLDIQITNSSLKDIQGALAATLEEGSWISTSYLVAEIIMIPMTAWLVQLLSARR 65 Query: 95 LLLAAAGLFTLFSVMCGLSTTLPMMIVGRIGQGFTGGALIPTAMTIIATRLPREQQPVGN 154 L + + F + S++C + L MIV R QGFTGGALIP A T+ +LP +P G Sbjct: 66 LAVMISVGFLVSSLLCSFAWNLESMIVFRAMQGFTGGALIPLAFTLALVKLPEHHRPKGM 125 Query: 155 ALFGATAILGPVLGPVLGGWLTENVSWHYSFFLNVPVGIALITLLLVAVPYERPKVELLA 214 ALF TA P +GP LGGWLTEN W Y F++NVP G+ +I LL + + P ELL Sbjct: 126 ALFAITATFAPSIGPTLGGWLTENFGWEYIFYINVPPGLLMIAGLLYGLEKKAPHWELLK 185 Query: 215 EADWLGILGMALGLGGLTVVLEEGEREQWFSSPDIRWLAVVSLLGFILLAIGQWRARHPV 274 D+ GI+ + +GLG L V LEEG R+ W S I L V+L +L I Q +P+ Sbjct: 186 STDYAGIVTLGIGLGCLQVFLEEGHRKDWLESQLIVSLGSVALFSLVLFVILQLSRPNPL 245 Query: 275 IQLRLLRDRQFGSVALMAMAVGVALYGTAYVIPQFLAGIAGYNSLQSGVIVLLSGVPMIL 334 I L +LR+R FG ++ ++ +G+ LYG+ YV+P +LA I GYN++Q G +++ G+P + Sbjct: 246 IDLGILRNRNFGLASISSIGLGMGLYGSIYVLPLYLAQIQGYNAMQIGEVIMWMGIPQLF 305 Query: 335 MMPFTPLLMRTVDIRLAVGVGLLLLAASAFMETDLSPLSYGGSFVASQLMRGIGTVLAML 394 ++P P LM+ V RL G L ++F L+P G F QL+R +G + M+ Sbjct: 306 LIPLVPKLMKLVSPRLLCAAGFGLFGLASFFSGVLNPDFAGPQFNQIQLLRALGQPMIMV 365 Query: 395 FLNQAAIRSVPASQAGDAAGIYSAARNLGGSLALASIAVIQDQRLWLHSRRLEESISANA 454 ++ A + AG A+ +++ RNLGG++ +A +A + D R ++ L E++ Sbjct: 366 TISLIATAYLQPQDAGSASSLFNILRNLGGAIGIALLATLLDSRAKVYFDYLREALVPTN 425 Query: 455 ELVQSSMATQAHLLGGPDIAIRLLGSTIQMQALTMTYADLFWLLGVAILCITPLVLFLRP 514 V +A A LG A+ L QA+ M Y D F ++G+ + VL R Sbjct: 426 PQVDERLAQLAAQLGSQQAALGKLSEITHQQAMIMAYNDAFHVIGMVLAVSMLAVLLTRS 485 Query: 515 LP 516 LP Sbjct: 486 LP 487 >mll0994 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 537 Score = 336 bits (862), Expect = 7e-92, Method: Compositional matrix adjust. Identities = 205/525 (39%), Positives = 297/525 (56%), Gaps = 18/525 (3%) Query: 2 SSPA-ASPGTGQTSGQTSGRKADASAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGA 60 S PA A P +T ++G A W+AV +LGA MA L+I IVN+SL IQG IGA Sbjct: 7 SMPAPARPARNETG--SAGTAASPRVWVAVVGSSLGAFMAVLNIQIVNASLADIQGAIGA 64 Query: 61 SGTEGTWIATAYLVAEIIIIPLSSWLEKLLGLRTLLLAAAGLFTLFSVMCGLSTTLPMMI 120 +G WI+TAYL+AEI++IPL+ WL ++ LR L+A A LF FSV C + L MI Sbjct: 65 GIDDGGWISTAYLIAEIVVIPLTGWLSQVFSLRNYLIANAVLFLAFSVACAFAANLGQMI 124 Query: 121 VGRIGQGFTGGALIPTAMTIIATRLPREQQPVGNALFGATAILGPVLGPVLGGWLTENVS 180 V R QGFTGG LIP A TI+ T LP+ +QP+G ALF +A P +GP +GG+LTEN Sbjct: 125 VLRAIQGFTGGVLIPMAFTIVITLLPKARQPIGLALFAMSATFAPAIGPTIGGYLTENWG 184 Query: 181 WHYSFFLNVPVGIALITLLLVAVPYERPKVELLAEADWLGILGMALGLGGLTVVLEEGER 240 W Y F++N+ G ++ +L ++ + ++ LL E DW GI MA+GL L VLEEG + Sbjct: 185 WQYIFYVNIVPGALMVGMLWFSLDRQPMRLALLGEGDWPGIATMAIGLAALQTVLEEGNK 244 Query: 241 EQWFSSPDIRWLAVVSLLGFILLAIGQWRARHPVIQLRLLRDRQFGSVALMAMAVGVALY 300 WF S + LA+V+ + L + + HP++ LRLL R FG L +G ALY Sbjct: 245 NDWFGSLFVLRLAIVAAVSLSLFVWIELTSSHPLLNLRLLLRRNFGFGILANFMLGTALY 304 Query: 301 GTAYVIPQFLAGIAGYNSLQSGVIVLLSGVPMILMMPFTPLLMRTVDIRLAVGVGLLLLA 360 G+ +++P +LA I GYN+ Q G+++ +G+P +L++P P LM+ D+RL + G L A Sbjct: 305 GSVFILPVYLARIQGYNAEQIGLVLAWTGLPQLLLIPLVPYLMQRFDVRLVIVTGFALFA 364 Query: 361 ASAFMETDLSPLSYGGSFVASQLMRGIGTVLAMLFLNQAAIRSVPASQAGDAAGIYSAAR 420 AS FM ++ ++R IG L L+ A+ + AG A+ +++ R Sbjct: 365 ASNFMNVHMTAGYASDQLFWPNIVRAIGQALVFAPLSAIAVSGIEQENAGSASSLFNMIR 424 Query: 421 NLGGSLALASIAVIQDQRLWLHSRRLEESISANAELVQSSMAT----------QAHLLGG 470 NLGG++ +A + +R HS L +SIS E +S +A H+L Sbjct: 425 NLGGAVGIALLQTFLTKRQQYHSNVLVQSISLFEEATRSRIAKLTAYFLSHGVSDHVLAA 484 Query: 471 PD--IAIRLLGSTIQMQALTMTYADLFWLLGVAILCITPLVLFLR 513 IAI L ++ QA M ++D F+LLGVA++ L L+ Sbjct: 485 QKGVIAIAL---RVRQQAFIMAFSDTFFLLGVALVIALAATLLLK 526 >RC0200 [GEPR] COG0477 Permeases of the major facilitator superfamily Rco Rickettsia conorii Length = 519 Score = 283 bits (724), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 179/502 (35%), Positives = 282/502 (56%), Gaps = 17/502 (3%) Query: 35 LGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIIIIPLSSWLEKLLGLRT 94 +G M+ LDI IV SSL I + AS E +W+ T+YL+AE+IIIP++ +L +LL R Sbjct: 24 VGMFMSVLDIQIVASSLSVIAAGLAASSDELSWVQTSYLIAEVIIIPITGFLARLLTTRI 83 Query: 95 LLLAAAGLFTLFSVMCGLSTTLPMMIVGRIGQGFTGGALIPTAMTIIATRLPREQQPVGN 154 AA FT+ S++C L+T + MI+ R QGF GGA+IPT + + P Q+P+ Sbjct: 84 SYFIAALGFTVMSILCSLATNIESMIIFRALQGFFGGAMIPTVFSTVFILFPASQRPIVT 143 Query: 155 ALFGATAILGPVLGPVLGGWLTENVSWHYSFFLNVPVGIALITLLLVAVPYERPKVELLA 214 L G + P LGP LGG++TE +SWH+ F LNV GI + T++ + +++P +LL Sbjct: 144 ILIGLVVTVAPTLGPTLGGYITEILSWHFMFLLNVIPGIFVCTVVFLYGDFDKPNYKLLK 203 Query: 215 EADWLGILGMALGLGGLTVVLEEGEREQWFSSPDIRWLAVVSLLGFILLAIGQWRARHPV 274 D+LGIL MAL LG L VLEEG ++ W I +L++ +LGFILL I + +P+ Sbjct: 204 NFDFLGILLMALTLGLLQYVLEEGNKKGWLEDNLILFLSITVVLGFILLIIRELTCINPI 263 Query: 275 IQLR--LLRDRQFGSVALMAMAVGVALYGTAYVIPQFLAGIAGYNSLQSGVIVLLSGVPM 332 + L+ L +D FG L + +G+ LYGT Y++P FL IAGY++LQ G ++++G Sbjct: 264 LDLKTFLYKDFTFG--CLYSFVMGIGLYGTVYILPLFLFTIAGYDTLQIGATMMVTGGAQ 321 Query: 333 ILMMPFT-PLLMRTVDIRLAVGVGLLLLAASAFMETDLSPLSYGGSFVASQLMRGIGTVL 391 L P +L VD+RL + +GL A + + L+P S +FV Q +RG+ + Sbjct: 322 FLSAPLAGRMLGLGVDLRLMLIIGLGGFALGCHLNSFLTPDSKFAAFVLPQFVRGLSLMF 381 Query: 392 AMLFLNQAAIRSVPASQAGDAAGIYSAARNLGGSLALASIAVIQDQRLWLHSRRLEESIS 451 + N A+ ++P + G+A+G+Y+ RNLGG++ LA I+ I + L E+IS Sbjct: 382 CFIPTNNIALGNMPKERVGNASGLYNLTRNLGGAVGLAIISTILTNDTKTFMQYLSENIS 441 Query: 452 ANAELVQSSMATQAHLLGG----PDIA-IRLLGSTIQMQALTMTYADLFWLLGVAILCIT 506 + + + + + LL G P+ A LL + + A + ++F ++G+ + Sbjct: 442 STSIMALEQLDSYTELLSGKVLNPEKASYLLLANKLNHDAFVIAINNIFNMIGLLFV--- 498 Query: 507 PLVLFLRPLPTN---AAPVAAH 525 ++ L P +N V AH Sbjct: 499 -FIMLLIPFTSNIKLTENVNAH 519 >RP157 [GEPR] COG0477 Permeases of the major facilitator superfamily Rpr Rickettsia prowazekii Length = 519 Score = 281 bits (718), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 172/492 (34%), Positives = 273/492 (55%), Gaps = 10/492 (2%) Query: 28 LAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIIIIPLSSWLE 87 LA +G M+ LDI IV SSL I + AS E +W+ T+YL+AE+IIIP++ +L Sbjct: 17 LAFFGMIVGMFMSVLDIQIVASSLSVIAAGLAASSDELSWVQTSYLIAEVIIIPITGFLA 76 Query: 88 KLLGLRTLLLAAAGLFTLFSVMCGLSTTLPMMIVGRIGQGFTGGALIPTAMTIIATRLPR 147 +LL R AA FT+ SV+C L+ + MI+ R QGF GGA+IP + + P Sbjct: 77 RLLSTRICYFIAALGFTIMSVLCSLANNIESMIIFRALQGFFGGAMIPLVFSTVYIIFPA 136 Query: 148 EQQPVGNALFGATAILGPVLGPVLGGWLTENVSWHYSFFLNVPVGIALITLLLVAVPYER 207 Q+P L G + P LGP LGG++TE +SWH+ F LNV GI + T++ + V +++ Sbjct: 137 SQRPTVTILIGLVVTVAPTLGPTLGGYITEILSWHFMFLLNVIPGIFVCTVVFLYVNFDK 196 Query: 208 PKVELLAEADWLGILGMALGLGGLTVVLEEGEREQWFSSPDIRWLAVVSLLGFILLAIGQ 267 P +LL D+LGIL M+L LG L VLEEG +E W I +L++ LGFILL I + Sbjct: 197 PNYQLLKNFDFLGILLMSLTLGLLQYVLEEGNKEGWLDDNLILFLSITVALGFILLIIRE 256 Query: 268 WRARHPVIQLR--LLRDRQFGSVALMAMAVGVALYGTAYVIPQFLAGIAGYNSLQSGVIV 325 +P++ L+ L +D FG + M G+ LYG Y++P FL IA Y++LQ G + Sbjct: 257 LTFINPILDLKTFLYKDFTFGCIYSFVM--GIGLYGAVYILPLFLFTIAEYDTLQIGATM 314 Query: 326 LLSGVPMILMMPFT-PLLMRTVDIRLAVGVGLLLLAASAFMETDLSPLSYGGSFVASQLM 384 +++GV L P +L +D+R+ + +GL A + + L+P S +F+ Q + Sbjct: 315 MVTGVAQFLSAPLAGRMLGLGIDLRMMLTIGLGGFALGCHLNSCLTPDSKFAAFILPQFV 374 Query: 385 RGIGTVLAMLFLNQAAIRSVPASQAGDAAGIYSAARNLGGSLALASIAVIQDQRLWLHSR 444 RG + + N A+ ++P + G+A+G+Y+ RNLGG++ LA I+ I + + Sbjct: 375 RGFSLMFCFIPTNNIALGNMPKEKVGNASGLYNLTRNLGGAVGLAIISTILSNDTKIFMQ 434 Query: 445 RLEESISANAELVQSSMATQAHLLGGPDI-----AIRLLGSTIQMQALTMTYADLFWLLG 499 L E+IS + + + + + LL G + + LL + + A + ++F ++G Sbjct: 435 YLSENISYTSIIALTRLDSYTELLSGKILNPEQGSYLLLANKLNNDAFVIAINNIFNMIG 494 Query: 500 VAILCITPLVLF 511 + + I L+ F Sbjct: 495 LLFVFIMLLIPF 506