BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0272.p (306 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM4270 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 234 1e-61 VC2103 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 212 8e-55 BS_ywbI [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 204 2e-52 PA3433 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 165 1e-40 SA2330 [K] COG0583 Transcriptional regulator Sau Staphylococcus ... 152 6e-37 >STM4270 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 295 Score = 234 bits (598), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 126/297 (42%), Positives = 185/297 (62%), Gaps = 4/297 (1%) Query: 1 MDIRALRYFSETVRLNSFSRAADALHVTQSTVSKMVRQLEDEIGAPLLIRAGRSLQLTDT 60 MDIR LRYF E VR SF+RAA+ L VTQ T+SKM++ LEDE+ LLIR GR L LTDT Sbjct: 1 MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDT 60 Query: 61 GRVVYEQAQQILAGVQRLNTEVNNTRNLRQGHLEIGIPPMVNILCTPVLKAFRERHPDIA 120 GRVV+E+ ILA ++L E+++ +L +G L +GIPPMV +L + FR+R+P + Sbjct: 61 GRVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVE 120 Query: 121 ITLLEDTGPQIEQRVVAGTLEIGMTVLPIAPELELEMTPVAAYPIWA-VAQAGRFQKNRS 179 + + E G ++Q V+ G L++ MT LP+ L + ++P+ V ++G++ S Sbjct: 121 LKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSLFSHPLCVLVPRSGQWTTGDS 180 Query: 180 TLPCRALKDMPLVLLNNEFGLTRTLRNMFRDTGIAPEVAAQSGQWDWLVAMALAGMGVAL 239 P AL + PL++ N +F L+R L +F + P +A +SGQWD+L AM AG+G+A+ Sbjct: 181 IAP-EALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAI 239 Query: 240 LPEPFIHRLASDQLQSVRLVEPEVQWQVAYVTRGG-YLSHAARAWLALSSELFAGGP 295 LPEP RL L+ + L E +++WQ+ + R G YLSH+ARAWL + P Sbjct: 240 LPEPICQRLDKATLRWLPL-ESDLRWQLGMIWREGVYLSHSARAWLTCCEGFWLKQP 295 >VC2103 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 292 Score = 212 bits (540), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 110/288 (38%), Positives = 173/288 (60%), Gaps = 2/288 (0%) Query: 1 MDIRALRYFSETVRLNSFSRAADALHVTQSTVSKMVRQLEDEIGAPLLIRAGRSLQLTDT 60 MDIRALRYF E V SF++A++ L VTQ T+SKM+R LE E+ PLL R GR LT+ Sbjct: 1 MDIRALRYFVELVNQQSFTKASERLFVTQPTISKMIRNLEQELEQPLLHREGRRFWLTEA 60 Query: 61 GRVVYEQAQQILAGVQRLNTEVNNTRNLRQGHLEIGIPPMVNILCTPVLKAFRERHPDIA 120 G +VY++AQQIL +Q+L+ E+ + L +GHL +GIPPMV + + + +R+ +P++ Sbjct: 61 GEIVYQRAQQILTQMQQLDAELTDLNQLHRGHLRLGIPPMVGHVYARLFRQYRQTYPNVE 120 Query: 121 ITLLEDTGPQIEQRVVAGTLEIGMTVLPIAPELELEMTPVAAYPIWAVAQAGRFQKNRST 180 +T++E G +IEQ ++ G +++ +T+L +L + YPI+AV ++ +T Sbjct: 121 LTVVEYGGRKIEQAILDGDIDVAVTMLSPNQHPDLNTVALDHYPIFAVVPDIPLWRSLTT 180 Query: 181 LPCRALKDMPLVLLNNEFGLTRTLRNMFRDTGIAPEVAAQSGQWDWLVAMALAGMGVALL 240 L + P L +EF L+ + + G P+VAA+S QWD+LVA+ +G+GV L Sbjct: 181 LTWAQISQEPFYLFTHEFTLSDHIHTCCQAAGYTPQVAARSSQWDFLVALVKSGVGVCFL 240 Query: 241 PEPFIHRLASDQLQSVRLVEPEVQWQVAYV-TRGGYLSHAARAWLALS 287 P P R+ D + + + P + W++ V R Y+S A AW+AL Sbjct: 241 PAPLCQRIQGDGV-LIYPITPAIDWRLGVVWHRERYVSKTAEAWIALC 287 >BS_ywbI [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 301 Score = 204 bits (518), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 105/286 (36%), Positives = 165/286 (57%), Gaps = 3/286 (1%) Query: 1 MDIRALRYFSETVRLNSFSRAADALHVTQSTVSKMVRQLEDEIGAPLLIRAGRSLQLTDT 60 MDIR L YF E RL SF++A+ +L+V+Q T+SKM++ LE+E+G L R GR ++LTD Sbjct: 1 MDIRHLTYFLEVARLKSFTKASQSLYVSQPTISKMIKNLEEELGIELFYRNGRQVELTDA 60 Query: 61 GRVVYEQAQQILAGVQRLNTEVNNTRNLRQGHLEIGIPPMVNILCTP-VLKAFRERHPDI 119 G +Y QAQ+I+ Q L +E+N+ +++GH+ IG+PPM+ P VL FRE +P++ Sbjct: 61 GHSMYVQAQEIIKSFQNLTSELNDIMEVKKGHVRIGLPPMIGSGFFPRVLGDFRENYPNV 120 Query: 120 AITLLEDTGPQIEQRVVAGTLEIGMTVLPIAPELELEMTPVAAYPIWAVAQAGRFQKNRS 179 L+ED ++++ V G+L+IG+ VLP ++ T V + V + R + Sbjct: 121 TFQLVEDGSIKVQEGVGDGSLDIGVVVLPANEDIFHSFTIVKETLMLVVHPSHRLADEKE 180 Query: 180 TLPCRALKDMPLVLLNNEFGLTRTLRNMFRDTGIAPEVAAQSGQWDWLVAMALAGMGVAL 239 R LKD P + +F L + G P + ++ QWD++ M A +G+ L Sbjct: 181 C-QLRELKDEPFIFFREDFVLHNRIMTECIKAGFRPHIIYETSQWDFISEMVSANLGIGL 239 Query: 240 LPEPFIHRLASDQLQSVRLVEPEVQWQVAYVTRGG-YLSHAARAWL 284 LPE L ++++ + LV+P + W +A + R YLS AARAWL Sbjct: 240 LPERICRGLDPEKVKVIPLVDPVIPWHLAIIWRKDRYLSFAARAWL 285 >PA3433 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 165 bits (418), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 101/291 (34%), Positives = 158/291 (54%), Gaps = 4/291 (1%) Query: 1 MDIRALRYFSETVRLNSFSRAADALHVTQSTVSKMVRQLEDEIGAPLLIRAGRSLQLTDT 60 M+ R LR F E VR SF++AA H +QST+SK V QLE +G +L R G ++LTD Sbjct: 1 MEFRQLRSFVEVVRQGSFTQAAQVRHASQSTISKQVAQLEQSLGVQVLERNGPHVRLTDA 60 Query: 61 GRVVYEQAQQILAGVQRLNTEVNNTRNLRQGHLEIGIPPM-VNILCTPVLKAFRERHPDI 119 G VV+ +A+++L + L +E+++ L +G L +G+P + + L +R R+P+I Sbjct: 61 GAVVFRRAEEMLRLRRDLLSELDDLSQLNRGELRLGLPLLGADALFAQRFAEYRRRYPNI 120 Query: 120 AITLLEDTGPQIEQRVVAGTLEIGMTVLPIAPELELEMTPVAAYPIWAVAQAGRFQKNRS 179 A+ L+E +EQ V+AG LE+ ++ P + + P P+ + AG + + Sbjct: 121 AVHLVEGGSKTMEQAVLAGELELAGSLTPADDGFDYQ--PFCNEPLDVLLPAGHPKAAAA 178 Query: 180 TLPCRALKDMPLVLLNNEFGLTRTLRNMFRDTGIAPEVAAQSGQWDWLVAMALAGMGVAL 239 ++ L D P +L F L L + G +P +SGQ D+L A+ A GV L Sbjct: 179 SVALGELADSPFLLYQQSFTLNDRLLRACLEAGFSPREGGRSGQADFLGALVAANQGVVL 238 Query: 240 LPEPFIHRLASDQLQSVRLVEPEVQWQVAYV-TRGGYLSHAARAWLALSSE 289 LP + + V L EP+++W +A++ RGGYLS AA+AWL L E Sbjct: 239 LPRVIAREIERPGVVRVLLREPDLRWDIAFIWRRGGYLSRAAQAWLELLRE 289 >SA2330 [K] COG0583 Transcriptional regulator Sau Staphylococcus aureus N315 Length = 295 Score = 152 bits (385), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 80/289 (27%), Positives = 156/289 (53%), Gaps = 6/289 (2%) Query: 1 MDIRALRYFSETVRLNSFSRAADALHVTQSTVSKMVRQLEDEIGAPLLIRAGRSLQLTDT 60 +DI+ ++YF E V+ + A+ +L++ Q T+SK ++ +E+E+G PL R+ R L LTD Sbjct: 4 VDIKHMKYFIEVVKQGGMTNASKSLYIAQPTISKAIKDIENEMGTPLFDRSKRHLILTDA 63 Query: 61 GRVVYEQAQQILAGVQRLNTEVNNTRNLRQGHLEIGIPPMVNI-LCTPVLKAFRERHPDI 119 G++ YE++++I+A L +E+ L GH+ +G+ ++N+ + +L AF +++P++ Sbjct: 64 GQIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMNMKILINILGAFHQQYPNV 123 Query: 120 AITLLEDTGPQIEQRVVAGTLEIGMTVLPIAPELELEMTPVAAYPI-WAVAQAGRFQKNR 178 L+E+ G IEQ+++ ++IG+T LP+ + + T + + V++ R K Sbjct: 124 TYNLIENGGKTIEQQIINDEVDIGVTTLPVDHHI-FDYTTLDKEDLRLIVSREHRLAK-Y 181 Query: 179 STLPCRALKDMPLVLLNNEFGLTRTLRNMFRDTGIAPEVAAQSGQWDWLVAMALAGMGVA 238 T+ L +L N +F L + ++ G P AQ QW + + +G++ Sbjct: 182 ETVKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTVAQISQWHVIEDLVTNELGIS 241 Query: 239 LLPEPFIHRLASDQLQSVRLVEPEVQWQVAYV-TRGGYLSHAARAWLAL 286 +LP +L D ++ +R+ + V W++ V + LSHA W+ Sbjct: 242 ILPTSISEQLNGD-VKLLRIEDAHVHWELGVVWKKDKQLSHATTKWIEF 289