BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0271.p (439 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5445 [C] COG0427 Acetyl-CoA hydrolase Pae Pseudomonas aeruginosa 597 e-170 AGc695 [C] COG0427 Acetyl-CoA hydrolase Atu Agrobacterium tumefa... 573 e-163 BMEI0928 [C] COG0427 Acetyl-CoA hydrolase Bme Brucella melitensis 551 e-156 Cgl2515 [C] COG0427 Acetyl-CoA hydrolase Cgl Corynebacterium glu... 401 e-111 CC3724 Non COG 399 e-111 >PA5445 [C] COG0427 Acetyl-CoA hydrolase Pae Pseudomonas aeruginosa Length = 497 Score = 597 bits (1538), Expect = e-170, Method: Compositional matrix adjust. Identities = 299/439 (68%), Positives = 352/439 (80%), Gaps = 2/439 (0%) Query: 1 MHSERIP-PTLAGKVMSAGDAARLFRTGMTIGMSGFTRAGDAKAIPRALAERGAEEALRF 59 M+ +R+ P+L KVMSA +AA L + GMT+GMSGFTRAG+AKA+P+ALA R E LR Sbjct: 1 MYRDRVRLPSLLDKVMSAAEAADLIQDGMTVGMSGFTRAGEAKAVPQALAMRAKERPLRI 60 Query: 60 TVITGASLGNDSDGLMAEAGLLARRMPFQVDAALRRKINAGEVMFIDQHLSETAEQLRNG 119 +++TGASLGND D + EAG+LARRMPFQVD+ LR+ INAGEVMFIDQHLSET EQLRN Sbjct: 61 SLMTGASLGNDLDKQLTEAGVLARRMPFQVDSTLRKAINAGEVMFIDQHLSETVEQLRNH 120 Query: 120 TLGPIDIAVVEAAAITSEG-IIPTMSVGNSASFIEQARMIVIELNTSVPAALAGLHDIYL 178 L DIAV+EAAAIT +G I+PT SVGNSASF A+ +++E+N + L GLHDIY+ Sbjct: 121 QLKLPDIAVIEAAAITEQGHIVPTTSVGNSASFAIFAKQVIVEINLAHSTNLEGLHDIYI 180 Query: 179 PQGRPGRQPIPLTSPEQRIGTRAIPFDPARIAAIVVTDMPDSPSSVLPPDDETKAIAGHV 238 P RP R PIPLT + RIG+ AIP P +I AIV+ D PDSPS+VLPPD ET+AIA H+ Sbjct: 181 PTYRPTRTPIPLTRVDDRIGSTAIPIPPEKIVAIVINDQPDSPSTVLPPDGETQAIANHL 240 Query: 239 IRFLEGEVAAGRMGEELAPLQAGIGTIANAVLHGLTQSSFRNLTMFSEVLQDSAIELLDS 298 I F + EV AGRM L PLQAGIG+IANAV+ GL +S F NLTM+SEVLQDS +L+D+ Sbjct: 241 IDFFKREVDAGRMSNSLGPLQAGIGSIANAVMCGLIESPFENLTMYSEVLQDSTFDLIDA 300 Query: 299 GQLRFASASSITLSSAMNDKFMRNLEYYRSRIVLRPQEISNHPELVRRLGIIALNTALEF 358 G+LRFAS SSITLS N NLE Y+ ++VLRPQEISNHPE+VRRLGII +NTALEF Sbjct: 301 GKLRFASGSSITLSPRRNADVFGNLERYKDKLVLRPQEISNHPEVVRRLGIIGINTALEF 360 Query: 359 DLYGNVNSTHVGGTHMMNGIGGSGDFARNGQLSIFVTKAAAKGGDISSVVPMVSHVDHTE 418 D+YGNVNSTHVGGT MMNGIGGSGDFARN L+IFVTK+ AKGG+ISSVVPMVSHVDHTE Sbjct: 361 DIYGNVNSTHVGGTKMMNGIGGSGDFARNAHLAIFVTKSIAKGGNISSVVPMVSHVDHTE 420 Query: 419 HDVDVLVTEFGLADLRGLA 437 HDVD+LVTE GLADLRGLA Sbjct: 421 HDVDILVTEQGLADLRGLA 439 >AGc695 [C] COG0427 Acetyl-CoA hydrolase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 470 Score = 573 bits (1477), Expect = e-163, Method: Compositional matrix adjust. Identities = 282/411 (68%), Positives = 330/411 (80%), Gaps = 1/411 (0%) Query: 28 MTIGMSGFTRAGDAKAIPRALAERGAEEALRFTVITGASLGNDSDGLMAEAGLLARRMPF 87 MT+GMSGFTRAG+AKA+P ALAER ++ T++TGASLGND D M EAG+LARRMPF Sbjct: 1 MTVGMSGFTRAGEAKAVPLALAERAKTNPMKITLMTGASLGNDLDKTMVEAGMLARRMPF 60 Query: 88 QVDAALRRKINAGEVMFIDQHLSETAEQLRNGTLGPIDIAVVEAAAITSEG-IIPTMSVG 146 Q D ALR+ IN G VMFIDQHLSET EQLR G + +DIA+VEA AIT+EG I+PT SVG Sbjct: 61 QSDPALRKAINDGRVMFIDQHLSETVEQLRGGQIHGVDIAIVEAVAITAEGGIVPTTSVG 120 Query: 147 NSASFIEQARMIVIELNTSVPAALAGLHDIYLPQGRPGRQPIPLTSPEQRIGTRAIPFDP 206 NSASF A +++E+N S P L GLHDI++P RP R PIP+ + + R+G IP P Sbjct: 121 NSASFAILADKVIVEINLSQPEVLEGLHDIFIPAKRPTRMPIPVVATDSRVGLPFIPVPP 180 Query: 207 ARIAAIVVTDMPDSPSSVLPPDDETKAIAGHVIRFLEGEVAAGRMGEELAPLQAGIGTIA 266 +IAAIV++D DS S+VLPPDDETKAIAGH+ FL EV GRM EL PLQAGIGTIA Sbjct: 181 EKIAAIVLSDKSDSFSTVLPPDDETKAIAGHLTEFLLNEVRHGRMTHELQPLQAGIGTIA 240 Query: 267 NAVLHGLTQSSFRNLTMFSEVLQDSAIELLDSGQLRFASASSITLSSAMNDKFMRNLEYY 326 NAV+HG + F +L M+SEVLQDS EL D+G+L FAS SSITLSSAMN++ M L Y Sbjct: 241 NAVMHGFIDTPFHDLKMYSEVLQDSTFELFDAGKLTFASGSSITLSSAMNEQVMPRLSEY 300 Query: 327 RSRIVLRPQEISNHPELVRRLGIIALNTALEFDLYGNVNSTHVGGTHMMNGIGGSGDFAR 386 +SR++LRPQE+SNHPE++RRLGII +NTALEFD+YGNVNSTHVGGTHMMNGIGGSGDFAR Sbjct: 301 KSRLILRPQEVSNHPEVIRRLGIIGINTALEFDIYGNVNSTHVGGTHMMNGIGGSGDFAR 360 Query: 387 NGQLSIFVTKAAAKGGDISSVVPMVSHVDHTEHDVDVLVTEFGLADLRGLA 437 N +SIFVTK+ AKGG ISSVVPMVSHVDHTEHDVD+LVTE GLADLRGLA Sbjct: 361 NAYMSIFVTKSIAKGGAISSVVPMVSHVDHTEHDVDILVTETGLADLRGLA 411 >BMEI0928 [C] COG0427 Acetyl-CoA hydrolase Bme Brucella melitensis Length = 496 Score = 551 bits (1420), Expect = e-156, Method: Compositional matrix adjust. Identities = 278/430 (64%), Positives = 327/430 (76%), Gaps = 1/430 (0%) Query: 9 TLAGKVMSAGDAARLFRTGMTIGMSGFTRAGDAKAIPRALAERGAEEALRFTVITGASLG 68 +L KV++A AA + GM +GMSGFTRAGDAKA+P A+A R A + + T+ITGASLG Sbjct: 10 SLRNKVITAEQAASFIKDGMIVGMSGFTRAGDAKAVPVAMAARAATDPFQITLITGASLG 69 Query: 69 NDSDGLMAEAGLLARRMPFQVDAALRRKINAGEVMFIDQHLSETAEQLRNGTLGPIDIAV 128 +D D L+ EA +L+RRMPFQ D LR IN GEVMFIDQHLSET EQLR+ +GPID AV Sbjct: 70 HDVDKLLTEAHILSRRMPFQADRTLRSAINRGEVMFIDQHLSETVEQLRSNQIGPIDCAV 129 Query: 129 VEAAAIT-SEGIIPTMSVGNSASFIEQARMIVIELNTSVPAALAGLHDIYLPQGRPGRQP 187 VEA AIT S GIIPT SVGNSAS A +++E+N + P AL GLHDIY+P RP R P Sbjct: 130 VEALAITESGGIIPTTSVGNSASLAILAEKVIVEVNLNQPMALEGLHDIYIPTKRPSRDP 189 Query: 188 IPLTSPEQRIGTRAIPFDPARIAAIVVTDMPDSPSSVLPPDDETKAIAGHVIRFLEGEVA 247 IP+ + + RIG IP P +IA IV+T DS S V P D ET AIAGH+I F +GEV Sbjct: 190 IPIMACDSRIGLPYIPIAPEKIAGIVITQENDSASPVEPADHETVAIAGHLIEFFKGEVV 249 Query: 248 AGRMGEELAPLQAGIGTIANAVLHGLTQSSFRNLTMFSEVLQDSAIELLDSGQLRFASAS 307 GR+ L PLQAGIGTIANAVL G S F NL M+SEVLQDS +L D+G+L FAS S Sbjct: 250 KGRLDLALNPLQAGIGTIANAVLTGFADSPFHNLRMYSEVLQDSTFDLFDAGKLDFASGS 309 Query: 308 SITLSSAMNDKFMRNLEYYRSRIVLRPQEISNHPELVRRLGIIALNTALEFDLYGNVNST 367 SITLS A ++ N++ YR R+VLRPQEISNHPE++RRLGII +NTALEFD+YGNVNST Sbjct: 310 SITLSPACGERVFNNIDRYRDRLVLRPQEISNHPEVIRRLGIIGINTALEFDIYGNVNST 369 Query: 368 HVGGTHMMNGIGGSGDFARNGQLSIFVTKAAAKGGDISSVVPMVSHVDHTEHDVDVLVTE 427 HV GT+MMNGIGGSGDFARN +SIFV+K+ AK G ISSVVPMV+HVDHTEHDVD+LVTE Sbjct: 370 HVDGTNMMNGIGGSGDFARNAYISIFVSKSEAKNGAISSVVPMVTHVDHTEHDVDILVTE 429 Query: 428 FGLADLRGLA 437 GLADLRGLA Sbjct: 430 QGLADLRGLA 439 >Cgl2515 [C] COG0427 Acetyl-CoA hydrolase Cgl Corynebacterium glutamicum Length = 502 Score = 401 bits (1030), Expect = e-111, Method: Compositional matrix adjust. Identities = 202/442 (45%), Positives = 289/442 (65%), Gaps = 7/442 (1%) Query: 3 SERI-PPTLAGKVMSAGDAARLFRTGMTIGMSGFTRAGDAKAIPRALAER-----GAEEA 56 S+RI L K+MSA +AA+ G +G SGFT AG KA+P A+A R GA Sbjct: 2 SDRIASEKLRSKLMSADEAAQFVNHGDKVGFSGFTGAGYPKALPTAIANRAKEAHGAGND 61 Query: 57 LRFTVITGASLGNDSDGLMAEAGLLARRMPFQVDAALRRKINAGEVMFIDQHLSETAEQL 116 + TGAS D DG++AEA + RMP+ D +R KIN+G + + D HLS + +Q+ Sbjct: 62 YAIDLFTGASTAPDCDGVLAEADAIRWRMPYASDPIMRNKINSGSMGYSDIHLSHSGQQV 121 Query: 117 RNGTLGPIDIAVVEAAAITSEG-IIPTMSVGNSASFIEQARMIVIELNTSVPAALAGLHD 175 G G +++AV+E IT EG IIP+ SVGN+ ++ A +++E+N+ L G+HD Sbjct: 122 EEGFFGQLNVAVIEITRITEEGYIIPSSSVGNNVEWLNAAEKVILEVNSWQSEDLEGMHD 181 Query: 176 IYLPQGRPGRQPIPLTSPEQRIGTRAIPFDPARIAAIVVTDMPDSPSSVLPPDDETKAIA 235 I+ P R +P+ P RIG I FD ++ A+V T+ D + P DD +K IA Sbjct: 182 IWSVPALPNRIAVPINKPGDRIGKTYIEFDTDKVVAVVETNTADRNAPFKPVDDISKKIA 241 Query: 236 GHVIRFLEGEVAAGRMGEELAPLQAGIGTIANAVLHGLTQSSFRNLTMFSEVLQDSAIEL 295 G+ + FLE EVAAGR+ + +Q+G+G + NAV+ GL +S F N+ ++EV+QD ++L Sbjct: 242 GNFLDFLESEVAAGRLSYDGYIMQSGVGNVPNAVMAGLLESKFENIQAYTEVIQDGMVDL 301 Query: 296 LDSGQLRFASASSITLSSAMNDKFMRNLEYYRSRIVLRPQEISNHPELVRRLGIIALNTA 355 +D+G++ ASA+S +LS +K + YR I+LRPQ+ISNHPE++RR+G+IA N Sbjct: 302 IDAGKMTVASATSFSLSPEYAEKMNNEAKRYRESIILRPQQISNHPEVIRRVGLIATNGL 361 Query: 356 LEFDLYGNVNSTHVGGTHMMNGIGGSGDFARNGQLSIFVTKAAAKGGDISSVVPMVSHVD 415 +E D+YGNVNST+V G+ +MNGIGGSGDF RNG +S F+T + AKGG IS++VP SH+D Sbjct: 362 IEADIYGNVNSTNVSGSRVMNGIGGSGDFTRNGYISSFITPSEAKGGAISAIVPFASHID 421 Query: 416 HTEHDVDVLVTEFGLADLRGLA 437 HTEHDV V+++E+G ADLRGLA Sbjct: 422 HTEHDVMVVISEYGYADLRGLA 443 >CC3724 Non COG Length = 514 Score = 399 bits (1024), Expect = e-111, Method: Compositional matrix adjust. Identities = 215/438 (49%), Positives = 282/438 (64%), Gaps = 13/438 (2%) Query: 10 LAGKVMSAGDAARLFRTGMTIGMSGFTRAGDAKAIPRALAER-----GAEEALRFTVITG 64 L KVMS DAA L G T+GMSGFT +G KA+P ALA R A + V TG Sbjct: 21 LKAKVMSPEDAAALIGPGETVGMSGFTGSGYPKAVPTALARRIEAEHAAGRPFKLRVWTG 80 Query: 65 ASLGNDSDGLMAEAGLLARRMPFQVDAALRRKINAGEVMFIDQHLSETAEQLRNGTLGPI 124 AS G + DG +A+A + R+P+ D R IN GE+ + D HLS+ A G LGP+ Sbjct: 81 ASTGPELDGALAKANGIEFRLPYNSDPIAREMINRGEMDYFDMHLSQVAPMAWQGFLGPL 140 Query: 125 DIAVVEAAAITSEG-IIPTMSVGNSASFIEQARMIVIELNTSVPAALAGLHDIY----LP 179 D A++E I S+G +IP+ SVGN+ ++IE+A +++E+N AL G+HDIY LP Sbjct: 141 DTALIEVTGIRSDGSLIPSSSVGNNKTWIERASKVILEVNRWQNPALEGMHDIYYGTALP 200 Query: 180 QGRPGRQPIPLTSPEQRIGTRAIPFDPARIAAIVVTDMPDSPSSVLPPDDETKAIAGHVI 239 P R+PIPLT P+QRIG DPA++ A+V TD PD P ++ +AIAGH++ Sbjct: 201 ---PDRRPIPLTRPDQRIGEPYFRCDPAKVVAVVETDTPDRNLPFDAPGEDHRAIAGHLL 257 Query: 240 RFLEGEVAAGRMGEELAPLQAGIGTIANAVLHGLTQSSFRNLTMFSEVLQDSAIELLDSG 299 F EVA GR+ L PLQ+G+G IANAV+ GL F T F+EVLQD + LL+SG Sbjct: 258 EFFRHEVARGRLPANLLPLQSGVGNIANAVMFGLVDGPFEGTTAFTEVLQDGMLALLESG 317 Query: 300 QLRFASASSITLSSAMNDKFMRNLEYYRSRIVLRPQEISNHPELVRRLGIIALNTALEFD 359 +L ASA++ +LS +L+ R R+VLRPQEISNHPEL+RRLG +A+N +E D Sbjct: 318 RLLSASATAFSLSPEAAHTLNADLDKLRDRLVLRPQEISNHPELIRRLGCLAMNGMIEAD 377 Query: 360 LYGNVNSTHVGGTHMMNGIGGSGDFARNGQLSIFVTKAAAKGGDISSVVPMVSHVDHTEH 419 ++G VNSTH+ G+ + NGIGGSGDFARN +SIF+ + AKGG IS++VP HVDH Sbjct: 378 IHGAVNSTHLMGSRIQNGIGGSGDFARNAYVSIFMAPSTAKGGKISTIVPKTPHVDHINQ 437 Query: 420 DVDVLVTEFGLADLRGLA 437 DV VLVTE GLADLR L+ Sbjct: 438 DVQVLVTEQGLADLRALS 455