BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0262.p (298 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0420 [L] COG0178 Excinuclease ATPase subunit Rso Ralstonia so... 445 e-125 PA4234 [L] COG0178 Excinuclease ATPase subunit Pae Pseudomonas a... 428 e-120 NMA1159 [L] COG0178 Excinuclease ATPase subunit NmA Neisseria me... 407 e-113 NMB0962 [L] COG0178 Excinuclease ATPase subunit Nme Neisseria me... 406 e-113 VC0394 [L] COG0178 Excinuclease ATPase subunit Vch Vibrio cholerae 402 e-112 >RSc0420 [L] COG0178 Excinuclease ATPase subunit Rso Ralstonia solanacearum Length = 954 Score = 445 bits (1145), Expect = e-125, Method: Compositional matrix adjust. Identities = 219/253 (86%), Positives = 239/253 (94%) Query: 45 APIGRTPRSNPATYTGLFTPIRDLFATVPAAKERGYSAGRFSFNVKGGRCEACQGDGVIK 104 +PIGRTPRSNPATYTGLFTPIR+L+A VPAAKERGY GRFSFNVKGGRCEACQGDGV+K Sbjct: 702 SPIGRTPRSNPATYTGLFTPIRELYAGVPAAKERGYDPGRFSFNVKGGRCEACQGDGVLK 761 Query: 105 VEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPLIARKL 164 VEMHFLPDVYVPCDVCHGKRYNRETLEV YKGKNITE+LEMTVE AH FF PVP++ RKL Sbjct: 762 VEMHFLPDVYVPCDVCHGKRYNRETLEVLYKGKNITEVLEMTVEQAHEFFAPVPVVRRKL 821 Query: 165 QTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDL 224 QTLLDVGLGYI+LGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDI+L Sbjct: 822 QTLLDVGLGYIRLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIEL 881 Query: 225 LLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNPES 284 LLKVIH+LRDQGNT+ IIEHNLDVIKTADW++DLGPEGGAGGG+IIA G+PE++A++ S Sbjct: 882 LLKVIHKLRDQGNTVVIIEHNLDVIKTADWLLDLGPEGGAGGGQIIAKGTPEEVAKSRAS 941 Query: 285 ITGHYLAPLLKKK 297 TG YLAPLLK+K Sbjct: 942 FTGKYLAPLLKRK 954 Score = 140 bits (352), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 79/193 (40%), Positives = 114/193 (59%), Gaps = 19/193 (9%) Query: 117 CDVCHGKRYNRETLEVQY----KGKNITEILEMTVEDAHTFFLPVPL------------- 159 C C G R RE V+ + + I EI + DA T+FL + L Sbjct: 414 CPECEGTRLRREARHVKLGDSDQARAIYEINGWPLRDALTYFLTLNLHGAKREIADKIVQ 473 Query: 160 -IARKLQTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLH 218 I +L L +VGL Y+ L +SA TLSGGEAQR++L+ ++ TG +Y+LDEP+ GLH Sbjct: 474 EITSRLNFLNNVGLDYLSLERSADTLSGGEAQRIRLASQIGSGLTG-VMYVLDEPSIGLH 532 Query: 219 FHDIDLLLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDI 278 D D L+ + LRD GN++ ++EH+ D+I+ +D V+D+GP G GG+IIA G+P I Sbjct: 533 QRDNDRLIGTLKHLRDLGNSVLVVEHDEDMIRASDHVVDIGPGAGVHGGQIIAEGTPRQI 592 Query: 279 ARNPESITGHYLA 291 R+P S+TG YL+ Sbjct: 593 ERSPGSLTGEYLS 605 >PA4234 [L] COG0178 Excinuclease ATPase subunit Pae Pseudomonas aeruginosa Length = 945 Score = 428 bits (1100), Expect = e-120, Method: Compositional matrix adjust. Identities = 198/254 (77%), Positives = 226/254 (88%) Query: 45 APIGRTPRSNPATYTGLFTPIRDLFATVPAAKERGYSAGRFSFNVKGGRCEACQGDGVIK 104 +PIGRTPRSNPATYTGLFTPIR+LF+ VP A+ RGY GRFSFNVKGGRCEACQGDGVIK Sbjct: 691 SPIGRTPRSNPATYTGLFTPIRELFSGVPEARSRGYGPGRFSFNVKGGRCEACQGDGVIK 750 Query: 105 VEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPLIARKL 164 VEMHFLPD+YVPCDVC GKRYNRETLE++YKGK+I E+LEMT+E+A FF VP +ARKL Sbjct: 751 VEMHFLPDIYVPCDVCKGKRYNRETLEIRYKGKSIHEVLEMTIEEAREFFDAVPALARKL 810 Query: 165 QTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDL 224 QTL+DVGL YIKLGQSATTLSGGEAQRVKLS ELSKRDTG+TLYILDEPTTGLHF DI Sbjct: 811 QTLMDVGLSYIKLGQSATTLSGGEAQRVKLSRELSKRDTGKTLYILDEPTTGLHFADIQQ 870 Query: 225 LLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNPES 284 LL V+HRLRD GNT+ +IEHNLDVIKTADW++DLGPEGG+ GG+IIA G+PE +A P+S Sbjct: 871 LLDVLHRLRDHGNTVVVIEHNLDVIKTADWLVDLGPEGGSKGGQIIANGTPEQVAEMPQS 930 Query: 285 ITGHYLAPLLKKKK 298 TGH+L PLL++ + Sbjct: 931 HTGHFLKPLLERDR 944 Score = 141 bits (356), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 75/190 (39%), Positives = 113/190 (59%), Gaps = 15/190 (7%) Query: 116 PCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPLIARK------------ 163 PC CHG R RE V + + I M V +A + + L R+ Sbjct: 405 PCPDCHGTRLRREARHVWVGDRTLPAITAMPVGEACEYAAGLSLTGRRGEIAAKILKEIR 464 Query: 164 --LQTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHD 221 LQ L++VGL Y+ L +SA TLSGGEAQR++L+ ++ G +YILDEP+ GLH D Sbjct: 465 DRLQFLVNVGLDYLTLDRSADTLSGGEAQRIRLASQIGAGLVG-VMYILDEPSIGLHQRD 523 Query: 222 IDLLLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARN 281 + LL + LR+ GNT+ ++EH+ D I+ AD+V+D+GP G GG+++A G+P+ + + Sbjct: 524 NERLLGTLTHLRNLGNTVIVVEHDEDAIRLADYVVDIGPGAGVHGGQVVAEGTPDQVMNH 583 Query: 282 PESITGHYLA 291 P+S+TG YL+ Sbjct: 584 PDSLTGKYLS 593 >NMA1159 [L] COG0178 Excinuclease ATPase subunit NmA Neisseria meningitidis Z2491 Length = 948 Score = 407 bits (1047), Expect = e-113, Method: Compositional matrix adjust. Identities = 199/250 (79%), Positives = 229/250 (91%) Query: 45 APIGRTPRSNPATYTGLFTPIRDLFATVPAAKERGYSAGRFSFNVKGGRCEACQGDGVIK 104 +PIGRTPRSNPATYTGLFTPIR+LFA+VP ++ERGY+ GRFSFNVKGGRCEACQGDGVIK Sbjct: 699 SPIGRTPRSNPATYTGLFTPIRELFASVPLSRERGYNVGRFSFNVKGGRCEACQGDGVIK 758 Query: 105 VEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPLIARKL 164 VEMHFLPDVYVPC+VCHGKRYNRETLE+QYKGKNI+++L+MTVE+A FF VP ++RKL Sbjct: 759 VEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEACEFFDAVPTVSRKL 818 Query: 165 QTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDL 224 QTL+DVGLGYI+LGQSATTLSGGEAQRVKL+LELSKRDTGRTLYILDEPTTGLHF DI L Sbjct: 819 QTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIAL 878 Query: 225 LLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNPES 284 LL+VI RL+ +GN++ IIEHNLDVIKTADW++DLGPEGG GGG+IIA GSPE++A+ S Sbjct: 879 LLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRIIASGSPEEVAKVKGS 938 Query: 285 ITGHYLAPLL 294 TG YL +L Sbjct: 939 YTGKYLKNIL 948 Score = 139 bits (351), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 73/189 (38%), Positives = 110/189 (58%), Gaps = 15/189 (7%) Query: 117 CDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPL--------------IAR 162 C C G R +E V G+ + E+ + H FF + L I Sbjct: 415 CPSCGGARLRKEARYVYVSGEPLHEVSAWPLTKTHRFFETLDLDGNKKQIAEKILKEITE 474 Query: 163 KLQTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDI 222 +L L++VGL Y+ L +SA TLSGGEAQR++L+ ++ TG +Y+LDEP+ GLH D Sbjct: 475 RLGFLINVGLDYLNLSRSAETLSGGEAQRIRLASQIGSGLTG-VMYVLDEPSIGLHQRDN 533 Query: 223 DLLLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNP 282 D LL + RLRD GN++ ++EH+ D I+ AD+V+D+GP G GG ++ +PE++A+ Sbjct: 534 DRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIADTPENVAKCE 593 Query: 283 ESITGHYLA 291 S+TG YL+ Sbjct: 594 NSVTGQYLS 602 >NMB0962 [L] COG0178 Excinuclease ATPase subunit Nme Neisseria meningitidis MC58 Length = 949 Score = 406 bits (1043), Expect = e-113, Method: Compositional matrix adjust. Identities = 199/251 (79%), Positives = 228/251 (90%) Query: 45 APIGRTPRSNPATYTGLFTPIRDLFATVPAAKERGYSAGRFSFNVKGGRCEACQGDGVIK 104 +PIGRTPRSNPATYTGLFTPIR+LFA VP ++ERGY+ GRFSFNVKGGRCEACQGDGVIK Sbjct: 699 SPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVKGGRCEACQGDGVIK 758 Query: 105 VEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPLIARKL 164 VEMHFLPDVYVPC+VCHGKRYNRETLE+QYKGKNI+++L+MTVE+A FF VP ++RKL Sbjct: 759 VEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEAREFFDAVPTVSRKL 818 Query: 165 QTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDL 224 QTL+DVGLGYI+LGQSATTLSGGEAQRVKL+LELSKRDTGRTLYILDEPTTGLHF DI L Sbjct: 819 QTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIAL 878 Query: 225 LLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNPES 284 LL+VI RL+ +GN++ IIEHNLDVIKTADW++DLGPEGG GGG+IIA GSPE +A+ S Sbjct: 879 LLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRIIAKGSPEQVAKVKGS 938 Query: 285 ITGHYLAPLLK 295 TG YL +L+ Sbjct: 939 YTGKYLKVVLR 949 Score = 139 bits (350), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 73/189 (38%), Positives = 110/189 (58%), Gaps = 15/189 (7%) Query: 117 CDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPL--------------IAR 162 C C G R +E V G+ + E+ + H FF + L I Sbjct: 415 CPSCGGARLRKEARYVYVSGEPLHEVSAWPLTKTHQFFETLDLDGNKKQIAEKILKEITE 474 Query: 163 KLQTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDI 222 +L L++VGL Y+ L +SA TLSGGEAQR++L+ ++ TG +Y+LDEP+ GLH D Sbjct: 475 RLGFLINVGLDYLNLSRSAETLSGGEAQRIRLASQIGSGLTG-VMYVLDEPSIGLHQRDN 533 Query: 223 DLLLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNP 282 D LL + RLRD GN++ ++EH+ D I+ AD+V+D+GP G GG ++ +PE++A+ Sbjct: 534 DRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIADTPENVAQCE 593 Query: 283 ESITGHYLA 291 S+TG YL+ Sbjct: 594 NSVTGQYLS 602 >VC0394 [L] COG0178 Excinuclease ATPase subunit Vch Vibrio cholerae Length = 940 Score = 402 bits (1034), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/251 (78%), Positives = 220/251 (87%) Query: 45 APIGRTPRSNPATYTGLFTPIRDLFATVPAAKERGYSAGRFSFNVKGGRCEACQGDGVIK 104 +PIGRTPRSNPATYTG+FTPIR+LFA ++ RGY GRFSFNV+GGRCEACQGDGVIK Sbjct: 690 SPIGRTPRSNPATYTGIFTPIRELFAGTQESRSRGYQPGRFSFNVRGGRCEACQGDGVIK 749 Query: 105 VEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPLIARKL 164 VEMHFLPDVYVPCDVC GKRYNRETLEV+YKGK I E+L+MTVEDA FF PVP+IARKL Sbjct: 750 VEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFDPVPVIARKL 809 Query: 165 QTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIDL 224 QTL+DVGL YI+LGQSATTLSGGEAQRVKL+ ELSKRDTG+TLYILDEPTTGLHFHDI Sbjct: 810 QTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQ 869 Query: 225 LLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARNPES 284 LL V+HRLRD GNT+ +IEHNLDVIKTADW+IDLGPEGG GGG IIA G+PED+A+ S Sbjct: 870 LLSVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEAS 929 Query: 285 ITGHYLAPLLK 295 T +L PLL Sbjct: 930 HTARFLKPLLN 940 Score = 146 bits (369), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 79/194 (40%), Positives = 115/194 (59%), Gaps = 15/194 (7%) Query: 116 PCDVCHGKRYNRETLEVQYKGKNITEILEMTVEDAHTFFLPVPL--------------IA 161 PC C G R E V + I+E+++ DA TFF + L I Sbjct: 404 PCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEIN 463 Query: 162 RKLQTLLDVGLGYIKLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHD 221 +LQ L++VGL Y+ L +SA TLSGGEAQR++L+ ++ G +Y+LDEP+ GLH D Sbjct: 464 DRLQFLVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVG-VMYVLDEPSIGLHQRD 522 Query: 222 IDLLLKVIHRLRDQGNTLAIIEHNLDVIKTADWVIDLGPEGGAGGGKIIAVGSPEDIARN 281 + LL+ + LR+ GNT+ ++EH+ D I+ AD VID+GP G GG ++A G+ E+I N Sbjct: 523 NERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIGPGAGVHGGMVVAEGNVEEIIAN 582 Query: 282 PESITGHYLAPLLK 295 P S+TG YL+ + K Sbjct: 583 PNSLTGQYLSGVKK 596