BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0233.p (220 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2885 [K] COG1309 Transcriptional regulator Pae Pseudomonas aer... 72 1e-12 Rv0158 [K] COG1309 Transcriptional regulator Mtu Mycobacterium t... 69 1e-11 MT0167 [K] COG1309 Transcriptional regulator MtC Mycobacterium t... 69 1e-11 DR2376 [K] COG1309 Transcriptional regulator Dra Deinococcus rad... 66 5e-11 BH2958 [K] COG1309 Transcriptional regulator Bha Bacillus halodu... 60 4e-09 >PA2885 [K] COG1309 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 198 Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 60/203 (29%), Positives = 95/203 (46%), Gaps = 32/203 (15%) Query: 17 GDDSDP---RSEILDAAALAFMTKGYAATSIDDVADILSATKGKIYHHYRKKADLFFDVH 73 G +DP R ++L AA F +KGY T++ D+A + G I+HH++ K ++ V Sbjct: 8 GQLTDPESARGKLLQTAAHLFRSKGYERTTVRDLASAVGIQSGSIFHHFKSKDEILRSVM 67 Query: 74 KRGMEMDLAAVQEAASKSHARAIDKLRAMTLAHITVIMDHLPYQRVAVQGLEMHLAGETT 133 + + + A ++ A + + + LR L I R +Q + M GE Sbjct: 68 EETILYNTALMRAALADA-----EDLRERVLGLI----------RCELQSI-MGGTGEAM 111 Query: 134 AA----QREVLSE----ILVLRDQYENLFRDTIRQVMTEGHAPDQDLQIVVKAFFGALNW 185 A R + +E IL LRD YE ++ D + + G+ D I+ + GAL+W Sbjct: 112 AVLVYEWRSLSAEGQAYILGLRDIYEQMWLDVLGEARLAGYCQG-DPFILRRFLTGALSW 170 Query: 186 TTIWFRPRA----DQTEDEKLAV 204 TT WFRP DQ +E LA+ Sbjct: 171 TTTWFRPEGPMSLDQLAEEALAL 193 >Rv0158 [K] COG1309 Transcriptional regulator Mtu Mycobacterium tuberculosis H37Rv Length = 214 Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 10/194 (5%) Query: 23 RSEILDAAALAFMTKGYAATSIDDVADILSATKGKIYHHYRKKADLFFDVHKRGMEMDLA 82 R E+L A F +GY T +DDVAD++ K +YH+Y K+ + FD++++ E LA Sbjct: 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 Query: 83 AVQEAASKSHARAIDKLRAMTLAHITVIMDHLPYQRVAVQGLEMHLAGETTAAQREVLSE 142 AV + S + A + L T+ +T I + +R AV E E + E ++E Sbjct: 73 AVHDDPSWT---AREALYQYTVRLLTAIASNP--ERAAVYFQEQPYITEWFTS--EQVAE 125 Query: 143 ILVLRDQYENLFRDTIRQVMTEGHAPDQDLQIVVKAFFGALNWTTIWFRPRADQTEDEKL 202 + Q I + + G + D +V + G + W RP +T E Sbjct: 126 VREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKE-- 183 Query: 203 AVANSISTFAIRGL 216 +A ST +RGL Sbjct: 184 -IAAEFSTALLRGL 196 >MT0167 [K] COG1309 Transcriptional regulator MtC Mycobacterium tuberculosis CDC1551 Length = 214 Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 10/194 (5%) Query: 23 RSEILDAAALAFMTKGYAATSIDDVADILSATKGKIYHHYRKKADLFFDVHKRGMEMDLA 82 R E+L A F +GY T +DDVAD++ K +YH+Y K+ + FD++++ E LA Sbjct: 13 REELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA 72 Query: 83 AVQEAASKSHARAIDKLRAMTLAHITVIMDHLPYQRVAVQGLEMHLAGETTAAQREVLSE 142 AV + S + A + L T+ +T I + +R AV E E + E ++E Sbjct: 73 AVHDDPSWT---AREALYQYTVRLLTAIASNP--ERAAVYFQEQPYITEWFTS--EQVAE 125 Query: 143 ILVLRDQYENLFRDTIRQVMTEGHAPDQDLQIVVKAFFGALNWTTIWFRPRADQTEDEKL 202 + Q I + + G + D +V + G + W RP +T E Sbjct: 126 VREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMTLGSYRWLRPSGRRTAKE-- 183 Query: 203 AVANSISTFAIRGL 216 +A ST +RGL Sbjct: 184 -IAAEFSTALLRGL 196 >DR2376 [K] COG1309 Transcriptional regulator Dra Deinococcus radiodurans Length = 197 Score = 66.2 bits (160), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 48/171 (28%), Positives = 77/171 (45%), Gaps = 10/171 (5%) Query: 23 RSEILDAAALAFMTKGYAATSIDDVADILSATKGKIYHHYRKKADLFFDVHKRGMEMDLA 82 R +I D A+ F +GY ATS+ D+A L G +Y H K +L ++ RG Sbjct: 9 REQIHDVASRLFSERGYHATSMRDLAGQLGMQGGSLYAHISGKEELLVEI-VRGASQQFD 67 Query: 83 AVQEAASKSHARAIDKLRAMTLAHITVIMDHLPYQRVAVQGLEMHLAGETTAAQREVLSE 142 + + A +KLR HI V+ D++ V + HL+ E A + Sbjct: 68 EALFSLRDVNLPADEKLREAMFRHIQVVADNMDSATVFFHEWK-HLSAEPYA-------Q 119 Query: 143 ILVLRDQYENLFRDTIRQVMTEG-HAPDQDLQIVVKAFFGALNWTTIWFRP 192 ++ RD + +RD + Q + +G D D++ A+NWT W+RP Sbjct: 120 VVAWRDTIDIFYRDLVAQGVRDGTFRADLDVRAAANLILSAVNWTYTWYRP 170 >BH2958 [K] COG1309 Transcriptional regulator Bha Bacillus halodurans Length = 215 Score = 59.7 bits (143), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 40/170 (23%), Positives = 77/170 (45%), Gaps = 10/170 (5%) Query: 23 RSEILDAAALAFMTKGYAATSIDDVADILSATKGKIYHHYRKKADLFFDVHKRGMEMDLA 82 + I++ A L F G+ A ++D + +KG YH+++ K +L + +H + L Sbjct: 6 KERIIETALLLFEEHGFHAVTVDRIVQESGTSKGGFYHNFKSKDELLYTIHDSFITYVLE 65 Query: 83 AVQEAASKSHARAIDKLRAMTLAHITVIMDHLPYQRVAVQGLEMHLAGETTAAQREVLSE 142 +EA K A ++L A + + + + P+ V Q E+ + + Sbjct: 66 KAREAYEKYETPA-ERLHATVRSFVMMFDFYRPHVTVFYQ--------ESLYLSSDYFKD 116 Query: 143 ILVLRDQYENLFRDTIRQVMTEGHAPDQ-DLQIVVKAFFGALNWTTIWFR 191 I RDQY+ L +++ + G ++ + I A FG +NWT W++ Sbjct: 117 IKKKRDQYKQLMFRLVKEGIDAGEFREEIPVPITSMAIFGMINWTYKWYK 166