BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0231.p (248 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 160 3e-39 SMb21633 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sme... 137 3e-32 AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu A... 133 5e-31 PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 127 3e-29 SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ss... 126 4e-29 >PA1021 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 253 Score = 160 bits (404), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 104/254 (40%), Positives = 142/254 (55%), Gaps = 12/254 (4%) Query: 3 SIVIVERSDAIACVTMNQPGRRNALAPEMREALTETLERLACDVDCRAIILAGTDRSFCA 62 S ++ E + + + P RRNAL+P +R L LE CD R+++L G + FCA Sbjct: 2 SGLLQETRGTVRLLRFDNPARRNALSPALRMELLRALEAAECDPSIRSVLLTGGEEVFCA 61 Query: 63 GGDLSSLPAGDALASRKRMTLAHRLLRTI---------XVDGTAFGAGMGLALACDYVLC 113 GGDL + + A R RM RL+R + V+G A GAG+ +ALACD ++C Sbjct: 62 GGDLGDMRVTELAAGRARMQDNARLVRQMVRMGKPLIAAVEGWAVGAGLSVALACDSIVC 121 Query: 114 SERARFCTAYSNVGLMADMGLLWSLPQRVSAGQVRRLLYTSAVVDGEEALRLGLADQLVH 173 ARF + VGL+AD+G L +LP R+ G+ R++L VV+ EEALR+GLAD+L Sbjct: 122 GAGARFAAGFGKVGLLADLGQLHTLPARIGWGRARQILMFGQVVEAEEALRIGLADRLCA 181 Query: 174 SDELQQAALDLAAQFAAAPPLAVGLTKAALARLPGSLDTVMGLELDGQLQLFSSADFTEG 233 + AL+LA + PL + +TKA LA L G EL Q QLF SAD EG Sbjct: 182 AGGALAMALELAGRVEQQAPLPLAMTKALLAEGLDLLLEREG-EL--QSQLFLSADHAEG 238 Query: 234 RHAFLEKRRPYFQG 247 + AFL KR P F+G Sbjct: 239 KAAFLAKRPPVFRG 252 >SMb21633 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sme Sinorhizobium meliloti Length = 263 Score = 137 bits (344), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 95/246 (38%), Positives = 123/246 (50%), Gaps = 13/246 (5%) Query: 16 VTMNQPGRRNALAPEMREALTETLERLACDVDCRAIILAGTDRSFCAG---GDLSSLPAG 72 +T+N+P + NA EM AL ER D D RA++L G R F AG GD G Sbjct: 18 LTLNRPDKLNAFNEEMHLALRAGFERARSDDDVRAVMLTGAGRGFSAGQDLGDRDPRKGG 77 Query: 73 DALASRKRMTLAHRLLRTI---------XVDGTAFGAGMGLALACDYVLCSERARFCTAY 123 R T + LLR I V+G A GAG +A ACD L + ARF A+ Sbjct: 78 APDLGRTIETFYNPLLRLIRSLEKPVVCAVNGVAAGAGANIAFACDITLAARSARFIQAF 137 Query: 124 SNVGLMADMGLLWSLPQRVSAGQVRRLLYTSAVVDGEEALRLGLADQLVHSDELQQAALD 183 + +GL+ D G WSLP+ V + + L T+ +D E A GL + V L A Sbjct: 138 AKIGLVPDSGGTWSLPRLVGEARAKALAMTAEPLDAETAASWGLIWRAVDDAALMDEASA 197 Query: 184 LAAQFAAAPPLAVGLTKAAL-ARLPGSLDTVMGLELDGQLQLFSSADFTEGRHAFLEKRR 242 LA + AA P +GLTK A+ A S D + LE D Q + SAD+ EG AFL+KR Sbjct: 198 LAVRLAAGPTRGLGLTKRAIQAAATHSFDEQLDLERDLQREAGRSADYAEGVTAFLDKRN 257 Query: 243 PYFQGR 248 P F+GR Sbjct: 258 PEFRGR 263 >AF0435 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Afu Archaeoglobus fulgidus Length = 256 Score = 133 bits (334), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 87/257 (33%), Positives = 135/257 (52%), Gaps = 18/257 (7%) Query: 5 VIVERSDAIACVTMNQPGRRNALAPEMREALTETLERLACDVDCRAIILAGTDRSFCAGG 64 V +E IA T+N+P + NAL + R L E +E + R +I+ G+ ++F AG Sbjct: 5 VKLELDGEIAVATLNRPEKLNALDTKTRMELAEVIE--GIEEVARVLIITGSGKAFAAGA 62 Query: 65 DLSSLPAGDALASRKRMTLAHRLLRTI---------XVDGTAFGAGMGLALACDYVLCSE 115 D++ L DA+ + + L L I V+G G G LA+ACD + SE Sbjct: 63 DINELLQRDAIKAFEATKLGTDLFSRIEELEIPVIAAVNGYTLGGGCELAMACDIRIASE 122 Query: 116 RARFCTAYSNVGLMADMGLLWSLPQRVSAGQVRRLLYTSAVVDGEEALRLGLADQLVHSD 175 +A+F N+ ++ G LP+ V G ++L+ T ++D + ALR+GL +++V + Sbjct: 123 KAKFGQPEINLAIIPGAGGTQRLPRLVGLGMAKKLVLTGEIIDAQTALRIGLVEEVVEHE 182 Query: 176 ELQQAALDLAAQFAAAPPLAVGLTKAALARLPGSLDTVM--GLELDGQL--QLFSSADFT 231 L + A ++AA+ PLAV + K AL S++ + GL + L LFSS D Sbjct: 183 RLMERAKEVAAKIIEKSPLAVKVAKKALN---ASINMPLKEGLRYEASLFALLFSSEDAK 239 Query: 232 EGRHAFLEKRRPYFQGR 248 EG AFLEKR+P F+GR Sbjct: 240 EGMRAFLEKRKPEFRGR 256 >PA1629 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 261 Score = 127 bits (318), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 92/258 (35%), Positives = 126/258 (48%), Gaps = 17/258 (6%) Query: 4 IVIVERSDA-IACVTMNQPGRRNALAPEMREALTETLERLACDVDCRAIILAGTDRSFCA 62 +V++E A IA + +N+P RNAL E+R+ L + L D R I+L G R F A Sbjct: 8 VVLLEFPAADIALLRLNRPQARNALNDEVRQRLASHFQTLGADPAIRVIVLTGDSRCFAA 67 Query: 63 GGDLSSLPAGDALASRKRMTLAHRLLRTIX---------VDGTAFGAGMGLALACDYVLC 113 G DL L A+ R R I V+G A G G LA+ CD ++ Sbjct: 68 GADLRDLSTSTAIGLYGRH--GERYWEAIARCPKPVIAAVNGFALGGGCELAMHCDLIVA 125 Query: 114 SERARFCTAYSNVGLMADMGLLWSLPQRVSAGQVRRLLYTSAVVDGEEALRLGLADQLVH 173 E A+F VG+M G L + V Q R+L+T +V +AL +GL ++V Sbjct: 126 GESAQFAQPEIKVGVMPGAGGTQRLVRAVGKFQALRMLFTGCLVKAPQALAMGLVSEVVA 185 Query: 174 SDELQQAALDLAAQFAAAPPLAVGLTKAAL---ARLPGSLDTVMGLELDGQLQLFSSADF 230 + AL+LA + A PPLA+ K + A LP LD+ + LE LF S D Sbjct: 186 DESTLARALELAMEIARLPPLALAQIKEVVLAGADLP--LDSALALERKAFQLLFDSQDQ 243 Query: 231 TEGRHAFLEKRRPYFQGR 248 EG HAFLEKR P +QG+ Sbjct: 244 KEGMHAFLEKRPPNYQGK 261 >SSO2514_2 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sso Sulfolobus solfataricus Length = 256 Score = 126 bits (317), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 80/260 (30%), Positives = 132/260 (50%), Gaps = 21/260 (8%) Query: 3 SIVIVERSDAIACVTMNQPGRRNALAPEMREALTETLERLACDVDCRAIILAGTDRSFCA 62 + +I+ +A + +N+P R NAL PE+ L ++L+ L D R +I+ G R+F A Sbjct: 2 NTLIIRIEPPLAWIILNRPERLNALNPELVSELDKSLDELESRSDVRVVIITGNGRAFSA 61 Query: 63 GGDLSSLPAGDALASRKRMTLAHRLLRTIX-------------VDGTAFGAGMGLALACD 109 G D+SS + R + R LR + ++G A G G+ LA+ACD Sbjct: 62 GADVSSF-----ITLRPIDVIRLRTLRNVVNKIALYTKPIIAGINGFALGGGLELAMACD 116 Query: 110 YVLCSERARFCTAYSNVGLMADMGLLWSLPQRVSAGQVRRLLYTSAVVDGEEALRLGLAD 169 + SE A+ N+G++ G LP+ V G+ + ++YT +V E+A ++GL D Sbjct: 117 IRIASEVAQLGQPEINIGIIPGAGGTQRLPRLVGKGKAKLMIYTGDMVSAEDAYKMGLVD 176 Query: 170 QLVHSDELQQAALDLAAQFAAAPPLAVGLTKAALARLPGSLDTVMGLELDGQL--QLFSS 227 +V S+ ++ +A + A P+++ K A+ L + G L+ L LF++ Sbjct: 177 LVVPSNRFEEEVRRVALKIAEKSPISLLAAKLAI-ELGYESNIWTGQTLESTLFGLLFTT 235 Query: 228 ADFTEGRHAFLEKRRPYFQG 247 D EG AFLEKR+P F+G Sbjct: 236 KDVEEGVKAFLEKRKPQFKG 255