BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0158.p (376 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ECs4724 [M] COG0399 Predicted pyridoxal phosphate-dependent enzy... 465 e-131 wecE [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme ... 462 e-130 ZwecE [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme... 462 e-130 YPO3859 [M] COG0399 Predicted pyridoxal phosphate-dependent enzy... 455 e-128 STM3925 [M] COG0399 Predicted pyridoxal phosphate-dependent enzy... 453 e-127 >ECs4724 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Ecs Escherichia coli O157:H7 Length = 376 Score = 465 bits (1196), Expect = e-131, Method: Compositional matrix adjust. Identities = 224/367 (61%), Positives = 275/367 (74%), Gaps = 1/367 (0%) Query: 3 IPFNRPYMVGKELDYIIQAKQGNMLAGDGPFTKRCHQWIETNTSCAKALLTHSCTAALEM 62 IPFN P +VG ELDY+ A L GDG FT+RC QW+E AK LLT SCTA+LEM Sbjct: 2 IPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAKVLLTPSCTASLEM 61 Query: 63 AALLLDIKPGDEIIMPSFTFVSTANAFVLRGGVPVFVDIREDTLNLDERLIEAAITTRTK 122 AALLLDI+PGDE+IMPS+TFVSTANAFVLRG VFVD+R DT+N+DE LIEAAIT +T+ Sbjct: 62 AALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTR 121 Query: 123 AIVPVHYAGVACEMDTIMDIAVRHGLRVVEDAAQGVMSKYKGKALGSIGDFGAFSFHETK 182 IVPVHYAGVACEMDTIM +A +H L VVEDAAQGVMS YKG+ALG+IG G FSFHETK Sbjct: 122 VIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETK 181 Query: 183 NVIS-GEGGALLVNDKSAALRAEIIREKGTDRSRFFRGEVDKYTWQEVGSSFLPGELIAA 241 N + GEGGA L+NDK+ RAEIIREKGT+RS+FFRG+VDKYTW+++GSS+L +L AA Sbjct: 182 NYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAA 241 Query: 242 FLWAQLEESETITARRLHSWEHYHAALASLESKGVLRRPVVPDACQHNAHMYYVLLAPGI 301 +LWAQLE ++ I +RL W++Y+ ALA L G + P +PD C NAHM+Y+ L Sbjct: 242 YLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCLQNAHMFYIKLRDIG 301 Query: 302 NRQQVLAELKRNQINSVFHYVPLHSSPAGLRYGRAHGELNWTVTQSERLVRLPMFVGLEE 361 +R ++ LK +I +VFHY+PLH PAG R+G HGE +T +SERL+RLP+F L Sbjct: 302 DRSALINFLKEAEIMAVFHYIPLHGCPAGERFGEFHGEDRYTTKESERLLRLPLFYNLSP 361 Query: 362 SQQDRVV 368 Q V+ Sbjct: 362 VNQRTVI 368 >wecE [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Eco Escherichia coli K12 Length = 376 Score = 462 bits (1190), Expect = e-130, Method: Compositional matrix adjust. Identities = 223/367 (60%), Positives = 274/367 (74%), Gaps = 1/367 (0%) Query: 3 IPFNRPYMVGKELDYIIQAKQGNMLAGDGPFTKRCHQWIETNTSCAKALLTHSCTAALEM 62 IPFN P +VG ELDY+ A L GDG FT+RC QW+E AK LLT SCTA+LEM Sbjct: 2 IPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAKVLLTPSCTASLEM 61 Query: 63 AALLLDIKPGDEIIMPSFTFVSTANAFVLRGGVPVFVDIREDTLNLDERLIEAAITTRTK 122 AALLLDI+PGDE+IMPS+TFVSTANAFVLRG VFVD+R DT+N+DE LIEAAIT +T+ Sbjct: 62 AALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTR 121 Query: 123 AIVPVHYAGVACEMDTIMDIAVRHGLRVVEDAAQGVMSKYKGKALGSIGDFGAFSFHETK 182 IVPVHYAGVACEMDTIM +A +H L VVEDAAQGVMS YKG+ALG+IG G FSFHETK Sbjct: 122 VIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETK 181 Query: 183 NVIS-GEGGALLVNDKSAALRAEIIREKGTDRSRFFRGEVDKYTWQEVGSSFLPGELIAA 241 N + GEGGA L+NDK+ RAEIIREKGT+RS+FFRG+VDKYTW+++GSS+L +L AA Sbjct: 182 NYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAA 241 Query: 242 FLWAQLEESETITARRLHSWEHYHAALASLESKGVLRRPVVPDACQHNAHMYYVLLAPGI 301 +LWAQLE ++ I +RL W++Y+ ALA L G + P +PD C NAHM+Y+ L Sbjct: 242 YLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCVQNAHMFYIKLRDID 301 Query: 302 NRQQVLAELKRNQINSVFHYVPLHSSPAGLRYGRAHGELNWTVTQSERLVRLPMFVGLEE 361 +R ++ LK +I +VFHY+PLH PAG +G HGE +T +SERL+RLP+F L Sbjct: 302 DRSALINFLKEAEIMAVFHYIPLHGCPAGEHFGEFHGEDRYTTKESERLLRLPLFYNLSP 361 Query: 362 SQQDRVV 368 Q V+ Sbjct: 362 VNQRTVI 368 >ZwecE [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis EcZ Escherichia coli O157:H7 EDL933 Length = 376 Score = 462 bits (1189), Expect = e-130, Method: Compositional matrix adjust. Identities = 223/367 (60%), Positives = 274/367 (74%), Gaps = 1/367 (0%) Query: 3 IPFNRPYMVGKELDYIIQAKQGNMLAGDGPFTKRCHQWIETNTSCAKALLTHSCTAALEM 62 IPFN P +VG ELDY+ A L GDG FT+RC QW+E AK LLT SCTA+LEM Sbjct: 2 IPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAKVLLTPSCTASLEM 61 Query: 63 AALLLDIKPGDEIIMPSFTFVSTANAFVLRGGVPVFVDIREDTLNLDERLIEAAITTRTK 122 AALLLDI+PGDE+IMPS+TFVSTANAFVLRG VFVD+R DT+N+DE LIEAAIT +T+ Sbjct: 62 AALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTR 121 Query: 123 AIVPVHYAGVACEMDTIMDIAVRHGLRVVEDAAQGVMSKYKGKALGSIGDFGAFSFHETK 182 IVPVHYAGVACEMDTIM +A +H L VVEDAAQGVMS YKG+ALG+IG G FSFHETK Sbjct: 122 VIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETK 181 Query: 183 NVIS-GEGGALLVNDKSAALRAEIIREKGTDRSRFFRGEVDKYTWQEVGSSFLPGELIAA 241 N + GE GA L+NDK+ RAEIIREKGT+RS+FFRG+VDKYTW+++GSS+L +L AA Sbjct: 182 NYTAGGEXGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAA 241 Query: 242 FLWAQLEESETITARRLHSWEHYHAALASLESKGVLRRPVVPDACQHNAHMYYVLLAPGI 301 +LWAQLE ++ I +RL W++Y+ ALA L G + P +PD C NAHM+Y+ L Sbjct: 242 YLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCLQNAHMFYIKLRDIG 301 Query: 302 NRQQVLAELKRNQINSVFHYVPLHSSPAGLRYGRAHGELNWTVTQSERLVRLPMFVGLEE 361 +R ++ LK +I +VFHY+PLH PAG R+G HGE +T +SERL+RLP+F L Sbjct: 302 DRSALINFLKEAEIMAVFHYIPLHGCPAGERFGEFHGEDRYTTKESERLLRLPLFYNLSP 361 Query: 362 SQQDRVV 368 Q V+ Sbjct: 362 VNQRTVI 368 >YPO3859 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Ype Yersinia pestis Length = 376 Score = 455 bits (1171), Expect = e-128, Method: Compositional matrix adjust. Identities = 224/368 (60%), Positives = 267/368 (72%), Gaps = 1/368 (0%) Query: 3 IPFNRPYMVGKELDYIIQAKQGNMLAGDGPFTKRCHQWIETNTSCAKALLTHSCTAALEM 62 IPFN P +VG EL Y+ A L GDG FT+RC QW+E +C K LLT SCTA+LEM Sbjct: 2 IPFNTPPIVGTELGYMQAAMSSGKLCGDGGFTRRCQQWMEKRFNCPKVLLTPSCTASLEM 61 Query: 63 AALLLDIKPGDEIIMPSFTFVSTANAFVLRGGVPVFVDIREDTLNLDERLIEAAITTRTK 122 AALLLDIKPGDE+IMPSFTFVSTANAFVLRG VFVDIR DT+N+DE IEAAIT +T+ Sbjct: 62 AALLLDIKPGDEVIMPSFTFVSTANAFVLRGAKMVFVDIRPDTMNIDETKIEAAITDKTR 121 Query: 123 AIVPVHYAGVACEMDTIMDIAVRHGLRVVEDAAQGVMSKYKGKALGSIGDFGAFSFHETK 182 IVPVHYAGVACEMDTIM +A +H L VVEDAAQGVMS YKGKALG+IG G FSFHETK Sbjct: 122 VIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMSTYKGKALGTIGHIGCFSFHETK 181 Query: 183 NVIS-GEGGALLVNDKSAALRAEIIREKGTDRSRFFRGEVDKYTWQEVGSSFLPGELIAA 241 N + GEGGA L+ND S RAEIIREKGT+RS+FFRG+VDKYTW+++GSS+L +L AA Sbjct: 182 NYTAGGEGGATLINDPSLIDRAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAA 241 Query: 242 FLWAQLEESETITARRLHSWEHYHAALASLESKGVLRRPVVPDACQHNAHMYYVLLAPGI 301 +LW QLE +E I RRL W Y+ A L G + PV+P NAHM+Y+ L Sbjct: 242 YLWGQLEAAEQINERRLALWHGYYNAFKPLADAGRIDLPVIPGNVVQNAHMFYIKLRDIE 301 Query: 302 NRQQVLAELKRNQINSVFHYVPLHSSPAGLRYGRAHGELNWTVTQSERLVRLPMFVGLEE 361 R ++ LK I +VFHY+PLH+ PAG +GR GE +T +SERLVRLP+F L + Sbjct: 302 ERSAFISYLKEADIMAVFHYIPLHACPAGEAFGRMAGEDRFTSKESERLVRLPIFYNLTD 361 Query: 362 SQQDRVVD 369 Q V++ Sbjct: 362 VNQSTVIN 369 >STM3925 [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Sty Salmonella typhimurium LT2 Length = 376 Score = 453 bits (1166), Expect = e-127, Method: Compositional matrix adjust. Identities = 219/367 (59%), Positives = 273/367 (74%), Gaps = 1/367 (0%) Query: 3 IPFNRPYMVGKELDYIIQAKQGNMLAGDGPFTKRCHQWIETNTSCAKALLTHSCTAALEM 62 IPFN P +VG EL+Y+ A L GDG FT+RC QW+E + AK LLT SCTA+LEM Sbjct: 2 IPFNAPPVVGTELEYMQSAMSSGKLCGDGGFTRRCQQWLEQHFGSAKVLLTPSCTASLEM 61 Query: 63 AALLLDIKPGDEIIMPSFTFVSTANAFVLRGGVPVFVDIREDTLNLDERLIEAAITTRTK 122 AALLLDI+PGDE+IMPSFTFVSTANAFVLRG VFVDIR DT+N+DE LIEAAIT +T+ Sbjct: 62 AALLLDIQPGDEVIMPSFTFVSTANAFVLRGAKIVFVDIRPDTMNIDETLIEAAITDKTR 121 Query: 123 AIVPVHYAGVACEMDTIMDIAVRHGLRVVEDAAQGVMSKYKGKALGSIGDFGAFSFHETK 182 AIVPVHYAGVACEMD IM +A ++ L VVEDAAQGVMS YKG+ALG+IG G FSFHETK Sbjct: 122 AIVPVHYAGVACEMDVIMALADKYNLFVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETK 181 Query: 183 NVIS-GEGGALLVNDKSAALRAEIIREKGTDRSRFFRGEVDKYTWQEVGSSFLPGELIAA 241 N + GEGGA L+ND++ RAEIIREKGT+RS+FFRG+VDKYTW+++GSS+L +L AA Sbjct: 182 NYTAGGEGGATLINDRTLIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQAA 241 Query: 242 FLWAQLEESETITARRLHSWEHYHAALASLESKGVLRRPVVPDACQHNAHMYYVLLAPGI 301 +LWAQLE ++ I +RL W+ Y+ AL L G P +P+ C HNAHM+Y+ L Sbjct: 242 YLWAQLEAADRINQQRLSLWQTYYDALTPLARAGRFELPSIPENCGHNAHMFYIKLRDIA 301 Query: 302 NRQQVLAELKRNQINSVFHYVPLHSSPAGLRYGRAHGELNWTVTQSERLVRLPMFVGLEE 361 +R ++ LK +I +VFHY+PLH PAG ++G G+ +T +SERL+RLP+F L Sbjct: 302 DRSALINFLKEAEIMAVFHYIPLHDCPAGDKFGEFIGDDVYTTKESERLLRLPLFYNLAP 361 Query: 362 SQQDRVV 368 Q V+ Sbjct: 362 VDQRTVI 368