BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0145.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5163 [M] COG1209 dTDP-glucose pyrophosphorylase Pae Pseudomona... 436 e-122 RSc0684 [M] COG1209 dTDP-glucose pyrophosphorylase Rso Ralstonia... 432 e-121 rfbA [M] COG1209 dTDP-glucose pyrophosphorylase Eco Escherichia ... 424 e-118 STM2095 [M] COG1209 dTDP-glucose pyrophosphorylase Sty Salmonell... 424 e-118 DRA0042 [M] COG1209 dTDP-glucose pyrophosphorylase Dra Deinococc... 405 e-113 >PA5163 [M] COG1209 dTDP-glucose pyrophosphorylase Pae Pseudomonas aeruginosa Length = 293 Score = 436 bits (1121), Expect = e-122, Method: Compositional matrix adjust. Identities = 209/293 (71%), Positives = 247/293 (84%) Query: 4 IQRKGIILAGGSGTRLYPVTQAVSKQLLPVHDKPMIYYPLSTLMLAGIRDILIISTPYDL 63 ++RKGIILAGGSGTRL+P T A+SKQLLPV+DKPMIYYPLSTLMLAGIR+ILIISTP D Sbjct: 1 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDT 60 Query: 64 PMFQRLLGDGSAWGISLSYAEQPSPDGLAQAFTIGRNFIGGHPSALILGDNIFYGNEFES 123 P FQ+LLGDGS WG+ L YA QPSPDGLAQAF IG +FIG SAL+LGDN++YG++F Sbjct: 61 PRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHE 120 Query: 124 QLRTADQQTDGAYVFAYYVTDPERYGVVDFDEQRRAISIEEKPVVPKSNYAVTGLYFYDR 183 L +A Q+ GA VFAY+V DPERYGVV+FD+ +AIS+EEKP+ PKSNYAVTGLYFYD+ Sbjct: 121 LLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQ 180 Query: 184 QVCDIAASVKPSARGELEITDVNRVYLEQNQLSVALMGRGMAWLDTGTHESLLDAGQFIS 243 QV DIA +KPS RGELEITDVNR YLE+ QLSV +MGRG AWLDTGTH+SLL+AGQFI+ Sbjct: 181 QVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIA 240 Query: 244 AIESRQGLKIACPEEIAFRKKYISADQLEVLAQPYIKNGYGKYLLSLLNSKIF 296 +E+RQGLK+ACPEEIA+R+K+I A QLE LA P KNGYG+YL LL ++ Sbjct: 241 TLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY 293 >RSc0684 [M] COG1209 dTDP-glucose pyrophosphorylase Rso Ralstonia solanacearum Length = 292 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 202/290 (69%), Positives = 244/290 (84%) Query: 6 RKGIILAGGSGTRLYPVTQAVSKQLLPVHDKPMIYYPLSTLMLAGIRDILIISTPYDLPM 65 RKGIILAGGSGTRLYP+T++VSKQLLPV+DKPMIYYPLSTLMLAGIRDILIISTP D P Sbjct: 2 RKGIILAGGSGTRLYPITRSVSKQLLPVYDKPMIYYPLSTLMLAGIRDILIISTPEDTPR 61 Query: 66 FQRLLGDGSAWGISLSYAEQPSPDGLAQAFTIGRNFIGGHPSALILGDNIFYGNEFESQL 125 F +LGDGS WGI+L YA QPSPDGLAQAF IGR+F+G PS LILGDNIF+G++ +QL Sbjct: 62 FTDMLGDGSKWGINLQYAVQPSPDGLAQAFIIGRDFVGNDPSTLILGDNIFHGHDLVAQL 121 Query: 126 RTADQQTDGAYVFAYYVTDPERYGVVDFDEQRRAISIEEKPVVPKSNYAVTGLYFYDRQV 185 + +Q GA VFAY+V DPERYGVV+FD+ RA+S+EEKP P+S+YAVTGLYFYD QV Sbjct: 122 TRSAEQQAGATVFAYHVHDPERYGVVEFDQNFRALSLEEKPAKPRSHYAVTGLYFYDNQV 181 Query: 186 CDIAASVKPSARGELEITDVNRVYLEQNQLSVALMGRGMAWLDTGTHESLLDAGQFISAI 245 CDIAA +KPSARGELEITDVN+ YL Q QL V +MGRG AWLDTGTH+SLL+A FI+ + Sbjct: 182 CDIAADIKPSARGELEITDVNKHYLAQGQLDVEIMGRGYAWLDTGTHDSLLEAAMFIATL 241 Query: 246 ESRQGLKIACPEEIAFRKKYISADQLEVLAQPYIKNGYGKYLLSLLNSKI 295 ++RQGL +ACPEEIA+R ++ISA+Q+ LA+P KNGYG+YL +++ + Sbjct: 242 QNRQGLMVACPEEIAYRNRWISAEQVAALAKPLSKNGYGQYLQHIISETV 291 >rfbA [M] COG1209 dTDP-glucose pyrophosphorylase Eco Escherichia coli K12 Length = 293 Score = 424 bits (1090), Expect = e-118, Method: Compositional matrix adjust. Identities = 201/285 (70%), Positives = 234/285 (82%) Query: 6 RKGIILAGGSGTRLYPVTQAVSKQLLPVHDKPMIYYPLSTLMLAGIRDILIISTPYDLPM 65 RKGIILAGGSGTRLYPVT AVSKQLLP++DKPMIYYPLSTLMLAGIRDILIISTP D P Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 66 FQRLLGDGSAWGISLSYAEQPSPDGLAQAFTIGRNFIGGHPSALILGDNIFYGNEFESQL 125 FQ+LLGDGS WG++L Y QPSPDGLAQAF IG FIGG AL+LGDNIFYG++ + Sbjct: 64 FQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLM 123 Query: 126 RTADQQTDGAYVFAYYVTDPERYGVVDFDEQRRAISIEEKPVVPKSNYAVTGLYFYDRQV 185 A + GA VFAY+V DPERYGVV+FD+ AIS+EEKP+ PKSNYAVTGLYFYD V Sbjct: 124 EAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISLEEKPLEPKSNYAVTGLYFYDNDV 183 Query: 186 CDIAASVKPSARGELEITDVNRVYLEQNQLSVALMGRGMAWLDTGTHESLLDAGQFISAI 245 +A ++KPSARGELEITD+NR+YLEQ +LSVA+MGRG AWLDTGTH+SL++A FI+ I Sbjct: 184 VQMAKNLKPSARGELEITDINRIYLEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243 Query: 246 ESRQGLKIACPEEIAFRKKYISADQLEVLAQPYIKNGYGKYLLSL 290 E RQGLK++CPEEIAFRK +I +Q+ LA P IKN YG+YL + Sbjct: 244 EERQGLKVSCPEEIAFRKGFIDVEQVRKLAVPLIKNNYGQYLYKM 288 >STM2095 [M] COG1209 dTDP-glucose pyrophosphorylase Sty Salmonella typhimurium LT2 Length = 292 Score = 424 bits (1090), Expect = e-118, Method: Compositional matrix adjust. Identities = 200/286 (69%), Positives = 237/286 (82%) Query: 6 RKGIILAGGSGTRLYPVTQAVSKQLLPVHDKPMIYYPLSTLMLAGIRDILIISTPYDLPM 65 RKGIILAGGSGTRLYPVT AVSKQLLP++DKPMIYYPLSTLMLAGIRDILIISTP D P Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 66 FQRLLGDGSAWGISLSYAEQPSPDGLAQAFTIGRNFIGGHPSALILGDNIFYGNEFESQL 125 FQ+LLGDGS WG++L Y QPSPDGLAQAF IG FIG AL+LGDNIFYG++ + Sbjct: 64 FQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGHDDCALVLGDNIFYGHDLPKLM 123 Query: 126 RTADQQTDGAYVFAYYVTDPERYGVVDFDEQRRAISIEEKPVVPKSNYAVTGLYFYDRQV 185 A + GA VFAY+V DPERYGVV+FD++ A+S+EEKP+ PKSNYAVTGLYFYD V Sbjct: 124 EAAVNKESGATVFAYHVNDPERYGVVEFDQKGTAVSLEEKPLQPKSNYAVTGLYFYDNSV 183 Query: 186 CDIAASVKPSARGELEITDVNRVYLEQNQLSVALMGRGMAWLDTGTHESLLDAGQFISAI 245 ++A ++KPSARGELEITD+NR+Y+EQ +LSVA+MGRG AWLDTGTH+SL++A FI+ I Sbjct: 184 VEMAKNLKPSARGELEITDINRIYMEQGRLSVAMMGRGYAWLDTGTHQSLIEASNFIATI 243 Query: 246 ESRQGLKIACPEEIAFRKKYISADQLEVLAQPYIKNGYGKYLLSLL 291 E RQGLK++CPEEIAFRK +I+A Q+ LA P KN YGKYLL ++ Sbjct: 244 EERQGLKVSCPEEIAFRKNFINAQQVIELAGPLSKNDYGKYLLKMV 289 >DRA0042 [M] COG1209 dTDP-glucose pyrophosphorylase Dra Deinococcus radiodurans Length = 296 Score = 405 bits (1040), Expect = e-113, Method: Compositional matrix adjust. Identities = 195/290 (67%), Positives = 229/290 (78%) Query: 6 RKGIILAGGSGTRLYPVTQAVSKQLLPVHDKPMIYYPLSTLMLAGIRDILIISTPYDLPM 65 RKGIILAGGSGTRLYP T AVSKQLLP++DKPMIYYPL+TLML G+R+ILIISTP D P Sbjct: 5 RKGIILAGGSGTRLYPATLAVSKQLLPIYDKPMIYYPLTTLMLGGMREILIISTPEDTPR 64 Query: 66 FQRLLGDGSAWGISLSYAEQPSPDGLAQAFTIGRNFIGGHPSALILGDNIFYGNEFESQL 125 F++LLGDGS WGI+L YA QP P+GLAQAF IG +F+ GHPS+LILGDNIFYGN+ + Sbjct: 65 FKQLLGDGSQWGIALEYAVQPKPEGLAQAFLIGEDFVQGHPSSLILGDNIFYGNDLSDLM 124 Query: 126 RTADQQTDGAYVFAYYVTDPERYGVVDFDEQRRAISIEEKPVVPKSNYAVTGLYFYDRQV 185 + A+ + +GA VFAY V DPERYGVVDFD RA+SIEEKP PKS++AVTGLYFYD +V Sbjct: 125 QAANAKENGATVFAYQVRDPERYGVVDFDRSGRALSIEEKPAQPKSDFAVTGLYFYDERV 184 Query: 186 CDIAASVKPSARGELEITDVNRVYLEQNQLSVALMGRGMAWLDTGTHESLLDAGQFISAI 245 +IA S+KPS RGELEITD+N VYLE+ L V LM RG AWLDTGTHES+LDA FI I Sbjct: 185 SEIARSIKPSPRGELEITDLNNVYLEEGALDVQLMRRGFAWLDTGTHESMLDASLFIQTI 244 Query: 246 ESRQGLKIACPEEIAFRKKYISADQLEVLAQPYIKNGYGKYLLSLLNSKI 295 E RQGLK+A PEEIA+R +IS L A+ KN YGKYL+ + K+ Sbjct: 245 EQRQGLKVASPEEIAWRSGWISTQALLEQAERLKKNQYGKYLIKIAQEKV 294