BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0143.p (654 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0679 [F] COG0044 Dihydroorotase and related cyclic amidohydro... 474 e-133 RSc0678 [F] COG0540 Aspartate carbamoyltransferase, catalytic ch... 385 e-106 PA0402 [F] COG0540 Aspartate carbamoyltransferase, catalytic cha... 305 2e-82 PA0401 [F] COG0044 Dihydroorotase and related cyclic amidohydrol... 269 2e-71 SMc01360 [F] COG0540 Aspartate carbamoyltransferase, catalytic c... 211 4e-54 >RSc0679 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases Rso Ralstonia solanacearum Length = 425 Score = 474 bits (1219), Expect = e-133, Method: Compositional matrix adjust. Identities = 229/304 (75%), Positives = 261/304 (85%), Gaps = 2/304 (0%) Query: 307 MKLHIKNGRLIDPANNIDAQQDVFVADGKVAGIGQAPRPFTADKTIDASGLVVAPGLVDL 366 MKLHIK GRLIDPAN IDAQQD+++A GKV G+G+AP F A+KTIDA+GLVV PGL+DL Sbjct: 1 MKLHIKGGRLIDPANGIDAQQDLYLAAGKVVGVGRAPADFHANKTIDATGLVVCPGLIDL 60 Query: 367 SARLREPGYEYKATLESEMQAAMQGGVTSLLCPPDTDPVLDEPGLVEMLKHRAKSLNQAH 426 SARLREPGYEYKATLESEM AAM GGVTSL+CPPDTDPVLDEPGLVEMLK RA++LNQAH Sbjct: 61 SARLREPGYEYKATLESEMAAAMAGGVTSLVCPPDTDPVLDEPGLVEMLKFRARNLNQAH 120 Query: 427 VYPLGALTMGLKGKALTEMAELTEAGCVGFSQADEPVLDTTVLLSALQYAKTFDYTVWLR 486 VYPLGALT+GLKG LTEMAELTEAGCVGFSQAD P+ DT VL+ ALQYA+TF +TVWLR Sbjct: 121 VYPLGALTVGLKGLVLTEMAELTEAGCVGFSQADAPMTDTLVLMRALQYAQTFGFTVWLR 180 Query: 487 PQDPHLGRHGIAHSGPAASRLGLSGVPVMSETIALYTIFELVRATGARVHLCRMSSAAGL 546 P+DP LG+ G+A SGP ASRLGL+GVPVM+ET+ L+TIFEL+R+TGARVHLCR+SSAAGL Sbjct: 181 PEDPFLGKGGVAASGPLASRLGLAGVPVMAETVRLHTIFELIRSTGARVHLCRLSSAAGL 240 Query: 547 ELVRAAKREGLPVTCDVGAHHIHLSDMDIGFFDSNARVNPPFRSQRDRDAI--XLKVGDI 604 ELVR AK EGLPVTCDV HHI L+D+DIG+F+S R PP R+ RDRD I L G I Sbjct: 241 ELVRRAKAEGLPVTCDVNVHHISLTDVDIGYFNSQMRFMPPLRAGRDRDGIVRALADGTI 300 Query: 605 ADVC 608 +C Sbjct: 301 DAIC 304 Score = 77.0 bits (188), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 30/55 (54%), Positives = 47/55 (85%) Query: 599 LKVGDIADVCIFDPKTRWTVEAKALASQGKHTPFLGYELSGQVKATIVSGHVAFE 653 L+ G +ADVC+FDP W VE ++L SQGK++P+LG+EL+G+V+AT+V+GH+A++ Sbjct: 369 LEEGAMADVCVFDPDATWKVEPRSLRSQGKNSPYLGFELAGRVRATLVAGHLAYD 423 >RSc0678 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain Rso Ralstonia solanacearum Length = 323 Score = 385 bits (990), Expect = e-106, Method: Compositional matrix adjust. Identities = 190/231 (82%), Positives = 208/231 (90%), Gaps = 6/231 (2%) Query: 3 NPQLNKNGELQHLLTIEGLPKAIITNILDTASSFVSI--GDREVKKVPLMRGKSVFNLFF 60 NPQL KNGEL+HLL+IEGL + I+T+ILDTA FVS+ DREVKKVPL+RGKSVFNLFF Sbjct: 7 NPQLTKNGELKHLLSIEGLSRDILTHILDTAKQFVSVSDADREVKKVPLLRGKSVFNLFF 66 Query: 61 ENSTRTRTTFEIASKRLSADVINLNISASSASKGESLLDTIDNLAAMHADMFVVRHSQSG 120 ENSTRTRTTFEIA+KRLSADVINLNI+ASS SKGESLLDTI+NL+AM ADMFVVRH+ SG Sbjct: 67 ENSTRTRTTFEIAAKRLSADVINLNINASSTSKGESLLDTINNLSAMQADMFVVRHASSG 126 Query: 121 APYLIAKHLIDTKQSHVHVVNAGDGRHAHPTQGLLDMYTIRHYKKDFTNLRVAIVGDILH 180 APYLIA+H+ HVHV+NAGDGRHAHPTQGLLDM+TIRHYKKDF+NL VAIVGDILH Sbjct: 127 APYLIAEHV----APHVHVINAGDGRHAHPTQGLLDMFTIRHYKKDFSNLTVAIVGDILH 182 Query: 181 SRVARSDIHGLTTLGVPEVRAIGPRTLLPSGLEQMGVRVFHNMEEGLKDVD 231 SRVARSDIH LTTLG EVRAIGPRTLLPSGLE MGVRVFH+MEEGLK VD Sbjct: 183 SRVARSDIHALTTLGCAEVRAIGPRTLLPSGLEHMGVRVFHSMEEGLKGVD 233 >PA0402 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain Pae Pseudomonas aeruginosa Length = 334 Score = 305 bits (781), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 150/228 (65%), Positives = 184/228 (80%), Gaps = 5/228 (2%) Query: 5 QLNKNGELQHLLTIEGLPKAIITNILDTASSFVSIGDREVKKVPLMRGKSVFNLFFENST 64 QLN G+L+H ++++GLP+ ++T ILDTA SF+ +G R VKKVPL+RGK+V N+FFENST Sbjct: 10 QLNDQGQLRHFISLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENST 69 Query: 65 RTRTTFEIASKRLSADVINLNISASSASKGESLLDTIDNLAAMHADMFVVRHSQSGAPYL 124 RTRTTFE+A++RLSADVI+LN+S SS SKGE+L DT+ NL AM ADMFVVRHS SGA + Sbjct: 70 RTRTTFELAAQRLSADVISLNVSTSSTSKGETLTDTLRNLEAMAADMFVVRHSDSGAAHF 129 Query: 125 IAKHLIDTKQSHVHVVNAGDGRHAHPTQGLLDMYTIRHYKKDFTNLRVAIVGDILHSRVA 184 IA+H+ +V V+N GDGRHAHPTQG+LDM TIR +K +F L VAIVGDILHSRVA Sbjct: 130 IAEHV----SPNVAVINGGDGRHAHPTQGMLDMLTIRRHKGNFEQLSVAIVGDILHSRVA 185 Query: 185 RSDIHGLTTLGVPEVRAIGPRTLLPSGL-EQMGVRVFHNMEEGLKDVD 231 RS++ L TLG P++R I PRTLLP GL EQ GVRVF N +EGLKDVD Sbjct: 186 RSNMLALKTLGCPDIRVIAPRTLLPIGLEEQYGVRVFTNADEGLKDVD 233 >PA0401 [F] COG0044 Dihydroorotase and related cyclic amidohydrolases Pae Pseudomonas aeruginosa Length = 423 Score = 269 bits (687), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 137/291 (47%), Positives = 182/291 (62%) Query: 307 MKLHIKNGRLIDPANNIDAQQDVFVADGKVAGIGQAPRPFTADKTIDASGLVVAPGLVDL 366 M + I+ R+IDPA+++D D+ + GK+ IG AP F+A KT+D +GLV APGLVDL Sbjct: 1 MTISIRGARVIDPASDLDQVGDLHIEAGKIVAIGAAPAGFSAQKTLDGAGLVAAPGLVDL 60 Query: 367 SARLREPGYEYKATLESEMQAAMQGGVTSLLCPPDTDPVLDEPGLVEMLKHRAKSLNQAH 426 S LREPGY K +ESE +AA GG TSL CPP T PVLD P + E++ RA+ A Sbjct: 61 SVALREPGYGRKGNVESETRAAAAGGTTSLCCPPYTRPVLDTPAVAELILDRAREAGNAK 120 Query: 427 VYPLGALTMGLKGKALTEMAELTEAGCVGFSQADEPVLDTTVLLSALQYAKTFDYTVWLR 486 VYP+GALT G G+ L+E+ L + GCV F+ +L AL+YA TFD TV Sbjct: 121 VYPIGALTRGFGGEQLSELVALRDTGCVAFTNGLHGFASNRILRRALEYAATFDLTVIFT 180 Query: 487 PQDPHLGRHGIAHSGPAASRLGLSGVPVMSETIALYTIFELVRATGARVHLCRMSSAAGL 546 QD L G+AH GP AS LGL+G+P +ET+AL LV +G R H +++SA G+ Sbjct: 181 SQDTDLAEGGLAHEGPTASFLGLAGIPETAETVALARNLLLVEQSGVRAHFSQLTSARGI 240 Query: 547 ELVRAAKREGLPVTCDVGAHHIHLSDMDIGFFDSNARVNPPFRSQRDRDAI 597 ELV A+ GLPVTCDV + + L+D + F S V PP R++ DR+A+ Sbjct: 241 ELVAQAQARGLPVTCDVALYQLILTDEALVGFSSLYHVQPPLRTRADREAL 291 >SMc01360 [F] COG0540 Aspartate carbamoyltransferase, catalytic chain Sme Sinorhizobium meliloti Length = 313 Score = 211 bits (537), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 112/220 (50%), Positives = 146/220 (66%), Gaps = 7/220 (3%) Query: 13 QHLLTIEGLPKAIITNILDTASSFVSIGDREVKKVPLMRGKSVFNLFFENSTRTRTTFEI 72 +HLL I+GL + IT +LD A V I + KK +RG + NLFFE STRT+++FE+ Sbjct: 7 RHLLGIKGLTEQDITLLLDRADEAVKISRQREKKTSSLRGLTQINLFFEASTRTQSSFEL 66 Query: 73 ASKRLSADVINLNISASSASKGESLLDTIDNLAAMHADMFVVRHSQSGAPYLIAKHLIDT 132 A KRL ADV+N+++ SS KGE+L+DT L AMH D+ VVRHS +GA L+A+ + Sbjct: 67 AGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMHPDVLVVRHSSAGAASLLAQKV--- 123 Query: 133 KQSHVHVVNAGDGRHAHPTQGLLDMYTIRHYKKDFTNLRVAIVGDILHSRVARSDIHGLT 192 VVNAGDG+H HPTQ LLD TIR K + + VAI GD+LHSRVARS+I L Sbjct: 124 ---SCSVVNAGDGQHEHPTQALLDALTIRRAKGKLSRIIVAICGDVLHSRVARSNILLLN 180 Query: 193 TLGVPEVRAIGPRTLLPSGLEQMGVRVFHNMEEGLKDVDF 232 +G VR + P TLLP+G+ +MG V+H+M EGLKD D Sbjct: 181 QMG-ARVRVVAPATLLPAGIAEMGAEVYHSMAEGLKDADV 219