BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0128.p (335 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2230_1 [L] COG0258 5'-3' exonuclease (including N-terminal do... 425 e-119 NMA0462_1 [L] COG0258 5'-3' exonuclease (including N-terminal do... 342 9e-94 NMB1982_1 [L] COG0258 5'-3' exonuclease (including N-terminal do... 339 5e-93 XF1103_1 [L] COG0258 5'-3' exonuclease (including N-terminal dom... 288 1e-77 YPO0017_1 [L] COG0258 5'-3' exonuclease (including N-terminal do... 281 2e-75 >RSc2230_1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) Rso Ralstonia solanacearum Length = 295 Score = 425 bits (1093), Expect = e-119, Method: Compositional matrix adjust. Identities = 205/282 (72%), Positives = 233/282 (82%), Gaps = 1/282 (0%) Query: 2 QKTLLLVDGSSYLYRAFHALPDMRNAEGAPTGALYGIINMLRRLRNDYPASYIACIFDAK 61 Q+TLLLVDGSSYLYRA+HALPD+RN EG PTGA+YGI+NMLR+LRNDYPA Y AC+FDAK Sbjct: 7 QETLLLVDGSSYLYRAYHALPDLRNGEGFPTGAIYGIVNMLRKLRNDYPAKYSACVFDAK 66 Query: 62 GKTFRDDLYAEYKATRKSMPEDLALQIEPIHAAVRALGWPILMVEGIEADDVIGTLGVRA 121 GKTFRD+LY YK R MP+DL QIEPIH AVRALGWPILMV+G+EADDVIGTL RA Sbjct: 67 GKTFRDELYPAYKEHRAPMPDDLRQQIEPIHEAVRALGWPILMVDGVEADDVIGTLAERA 126 Query: 122 AEEGLKTVVSTGDKDMAQLVNDHVTLVNTMSNETMDRAGVIGKFGVPPERIVDYLSLIGD 181 A EG++TVVSTGDKD+AQLVNDHVTLVNTMSNET+D AGV+ KFGVPP +IVDYLSLIGD Sbjct: 127 AREGIRTVVSTGDKDLAQLVNDHVTLVNTMSNETLDPAGVLAKFGVPPGKIVDYLSLIGD 186 Query: 182 TVDNVPGVEKCGPKTAVKWLTQYDSLDGIIANADKITGVVGENLRKALPWLPQARVLVTV 241 TVDNVPGV K GPKTAVKWL +Y SLD +IA A +I GVVGENLR L WLP+ R L+TV Sbjct: 187 TVDNVPGVPKVGPKTAVKWLGEYGSLDSVIARAGEIKGVVGENLRNTLDWLPKGRELLTV 246 Query: 242 KTDCDLSAHMGTILDSLTVQANDNDALREIFTRYNFRTWLRE 283 KTDCDL+ + T ++L D L + F RY F+TWLRE Sbjct: 247 KTDCDLATEVPT-FEALVDGGEDRAKLVDFFGRYGFKTWLRE 287 >NMA0462_1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) NmA Neisseria meningitidis Z2491 Length = 300 Score = 342 bits (876), Expect = 9e-94, Method: Compositional matrix adjust. Identities = 171/292 (58%), Positives = 214/292 (73%), Gaps = 1/292 (0%) Query: 4 TLLLVDGSSYLYRAFHAL-PDMRNAEGAPTGALYGIINMLRRLRNDYPASYIACIFDAKG 62 TLLLVDGSSYLYRA+HA+ ++ +GAPTGALYG++NMLRRLR++YP Y A +FDAKG Sbjct: 6 TLLLVDGSSYLYRAYHAMGQNLTAPDGAPTGALYGVLNMLRRLRSEYPHDYCAVVFDAKG 65 Query: 63 KTFRDDLYAEYKATRKSMPEDLALQIEPIHAAVRALGWPILMVEGIEADDVIGTLGVRAA 122 K FR ++ EYKATR MP+DL Q E + VR GWP+L++ +EADDVIGTL + A Sbjct: 66 KNFRHQMFEEYKATRPPMPDDLRPQAEALPDLVRLTGWPVLVIGQVEADDVIGTLAKQGA 125 Query: 123 EEGLKTVVSTGDKDMAQLVNDHVTLVNTMSNETMDRAGVIGKFGVPPERIVDYLSLIGDT 182 E GL+ +VSTGDKDMAQLV++ VTLVNTMS+ET+D GV KFGV P++I DYL+L+GD Sbjct: 126 EHGLRVIVSTGDKDMAQLVDERVTLVNTMSSETLDIEGVKAKFGVRPDQIRDYLALMGDK 185 Query: 183 VDNVPGVEKCGPKTAVKWLTQYDSLDGIIANADKITGVVGENLRKALPWLPQARVLVTVK 242 VDNVPGVEKCGPKTAVKWL Y SL G+I +A +I G VGENL+ ALP LP + LVT+K Sbjct: 186 VDNVPGVEKCGPKTAVKWLEAYGSLQGVIEHASEIKGKVGENLQAALPQLPLSYDLVTIK 245 Query: 243 TDCDLSAHMGTILDSLTVQANDNDALREIFTRYNFRTWLRELDAAASAASAD 294 TD DL A + ++SL L F R+ FRTWL+E ++ + S D Sbjct: 246 TDVDLHAELSDGIESLRCTTPKWAQLVVDFKRWGFRTWLKEAESNMNTGSTD 297 >NMB1982_1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) Nme Neisseria meningitidis MC58 Length = 300 Score = 339 bits (870), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 170/292 (58%), Positives = 214/292 (73%), Gaps = 1/292 (0%) Query: 4 TLLLVDGSSYLYRAFHAL-PDMRNAEGAPTGALYGIINMLRRLRNDYPASYIACIFDAKG 62 TLLLVDGSSYLYRA+HA+ ++ +GAPTGALYG++NMLRRLR++YP Y A +FDAKG Sbjct: 6 TLLLVDGSSYLYRAYHAMGQNLTAPDGAPTGALYGVLNMLRRLRSEYPHDYCAVVFDAKG 65 Query: 63 KTFRDDLYAEYKATRKSMPEDLALQIEPIHAAVRALGWPILMVEGIEADDVIGTLGVRAA 122 K FR ++ EYKATR MP+DL Q E + VR GWP+L++ +EADDVIGTL + A Sbjct: 66 KNFRHQMFEEYKATRPPMPDDLRPQAEALPDLVRLTGWPVLVIGQVEADDVIGTLAKQGA 125 Query: 123 EEGLKTVVSTGDKDMAQLVNDHVTLVNTMSNETMDRAGVIGKFGVPPERIVDYLSLIGDT 182 E GL+ +VSTGDKDMAQLV++ VTLVNTMS+ET+D GV KFGV P++I DYL+L+GD Sbjct: 126 EHGLRVIVSTGDKDMAQLVDERVTLVNTMSSETLDIEGVKAKFGVRPDQIRDYLALMGDK 185 Query: 183 VDNVPGVEKCGPKTAVKWLTQYDSLDGIIANADKITGVVGENLRKALPWLPQARVLVTVK 242 VDNVPGVEKCGPKTAVKWL Y SL G++ +A +I G VGENL+ ALP LP + LVT+K Sbjct: 186 VDNVPGVEKCGPKTAVKWLEAYGSLAGVMEHASEIKGKVGENLQAALPQLPLSYDLVTIK 245 Query: 243 TDCDLSAHMGTILDSLTVQANDNDALREIFTRYNFRTWLRELDAAASAASAD 294 TD DL A + ++SL L F R+ FRTWL+E ++ + S D Sbjct: 246 TDVDLHAELSDGIESLRRTTPKWAQLVVDFKRWGFRTWLKEAESNMNTGSTD 297 >XF1103_1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) Xfa Xylella fastidiosa 9a5c Length = 272 Score = 288 bits (738), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 153/274 (55%), Positives = 192/274 (70%), Gaps = 6/274 (2%) Query: 5 LLLVDGSSYLYRAFHALPDMRNAEGAPTGALYGIINMLRRLRNDYPASYIACIFDAKGKT 64 L+L+DGSSYLYRAFHALP + NA G PTGAL+G++NMLR + P Y A + DA GKT Sbjct: 4 LVLIDGSSYLYRAFHALPPLSNAAGEPTGALFGVVNMLRTTLKERP-DYAAFVIDAPGKT 62 Query: 65 FRDDLYAEYKATRKSMPEDLALQIEPIHAAVRALGWPILMVEGIEADDVIGTLGVRAAEE 124 FRD L +EYK R MP+DL +Q+EP+ V+ALG IL ++G+EADDVIGTL + A + Sbjct: 63 FRDALDSEYKMHRPPMPDDLRVQVEPMCGIVQALGIDILCIDGVEADDVIGTLALAAVAD 122 Query: 125 GLKTVVSTGDKDMAQLVNDHVTLVNTMSNETMDRA-GVIGKFGVPPERIVDYLSLIGDTV 183 G+ +STGDKD AQLV V LVNTM+ MD A VI KFGV P++I+D+L+L+GD V Sbjct: 123 GIAVTISTGDKDFAQLVRPGVELVNTMTGSRMDSAMAVINKFGVAPDQIIDFLALMGDAV 182 Query: 184 DNVPGVEKCGPKTAVKWLTQYDSLDGIIANADKITGVVGENLRKALPWLPQARVLVTVKT 243 DNVPGV+KCGPKTA KWL +Y SLD +IANADKI G +G+NLR LP L R L+T+KT Sbjct: 183 DNVPGVDKCGPKTAAKWLAEYGSLDAVIANADKIKGKIGDNLRVVLPRLLLNRALITIKT 242 Query: 244 DCDLSAHMGTILDSLTVQANDNDALREIFTRYNF 277 D L L ++ D +ALR + RY F Sbjct: 243 DVVLE----KCPQDLALRERDTEALRGFYQRYGF 272 >YPO0017_1 [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) Ype Yersinia pestis Length = 287 Score = 281 bits (718), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 140/283 (49%), Positives = 187/283 (66%), Gaps = 11/283 (3%) Query: 5 LLLVDGSSYLYRAFHALPDMRNAEGAPTGALYGIINMLRRLRNDYPASYIACIFDAKGKT 64 LLLVDGSSYLYRA+HA P + N G PTGA+YG++NMLR L Y S++A +FDAKGKT Sbjct: 9 LLLVDGSSYLYRAYHAFPPLTNGSGEPTGAMYGVLNMLRSLLLQYRPSHVAVVFDAKGKT 68 Query: 65 FRDDLYAEYKATRKSMPEDLALQIEPIHAAVRALGWPILMVEGIEADDVIGTLGVRAAEE 124 FRD+L+AEYK+ R MP+DL +QIEP+H V+A+G P+L+V G+EADDVIGTL A + Sbjct: 69 FRDELFAEYKSHRPPMPDDLRVQIEPLHQMVKAMGLPLLVVSGVEADDVIGTLAREAEKA 128 Query: 125 GLKTVVSTGDKDMAQLVNDHVTLVNTMSNETMDRAGVIGKFGVPPERIVDYLSLIGDTVD 184 G ++STGDKDMAQLV ++TL+NTM+N + V K+GVPPE I+D+L+L+GD+ D Sbjct: 129 GHSVLISTGDKDMAQLVTPNITLINTMNNTILGPQDVCDKYGVPPELIIDFLALMGDSSD 188 Query: 185 NVPGVEKCGPKTAVKWLTQYDSLDGIIANADKITGVVGENLRKALPWLPQAR-------V 237 N+PGV G KTA L LD + +N DKI+ + + L Q + Sbjct: 189 NIPGVPGVGEKTAQALLQGLGGLDTLFSNLDKISTLTFRGAKTMSAKLEQNKDVAYLSYK 248 Query: 238 LVTVKTDCDLSAHMGTILDSLTVQANDNDALREIFTRYNFRTW 280 L T+KTD +L D LTV D+ L ++F+RY F+ W Sbjct: 249 LATIKTDVELDV----TCDELTVSPPDDKQLHQLFSRYEFKRW 287