BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0104.p (438 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1993 [GEPR] COG0477 Permeases of the major facilitator superfa... 422 e-118 yhhS [GEPR] COG0477 Permeases of the major facilitator superfami... 355 1e-97 ZyhhS [GEPR] COG0477 Permeases of the major facilitator superfam... 352 9e-97 ECs4322 [GEPR] COG0477 Permeases of the major facilitator superf... 352 9e-97 STM3581 [GEPR] COG0477 Permeases of the major facilitator superf... 332 7e-91 >PA1993 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 402 Score = 422 bits (1086), Expect = e-118, Method: Compositional matrix adjust. Identities = 224/391 (57%), Positives = 288/391 (73%) Query: 41 PAIPHSQTAVMIQILSTVLFTFLAYMTIGIPLAVLPGYVHLDLGYSSFIAGLSISVQYLS 100 PA ++ V +QI+S V+FTF+ Y+TIGIPLAVLPGYVH DLGY S +AGL IS+QYL+ Sbjct: 10 PAQDSARQNVTLQIVSVVMFTFIGYLTIGIPLAVLPGYVHDDLGYGSVLAGLVISLQYLA 69 Query: 101 TFITRAQAGRMVDTIGPKKTVMRGMLACVASGAFLVLAAWSAELPWLSLSMILVSRFCLG 160 T + R AGR++D +GPK+ V+ GM ASG F++L+ P LSL+ +LV R LG Sbjct: 70 TLLARPYAGRVIDGLGPKRAVLYGMAGSAASGLFMLLSVAIQGWPALSLASLLVGRLVLG 129 Query: 161 IGESLAGTGSIIWGIGRIGATHTARMISWNGIATYGALAIGAPLGVALLHVGGFAAIGFL 220 ESL G+ +I WGIGR+GA HTA++ISWNGIA+YGA+A+GAPLGV L+ G ++G Sbjct: 130 AAESLVGSAAIGWGIGRVGAPHTAKVISWNGIASYGAIALGAPLGVLLVQWLGLWSMGAS 189 Query: 221 ALALPLIGYVIARRRPAVPVVRGERLAFRLVLNRVLPYGIGLALGTVGFGAIATFITLYY 280 + L +G+ +A + P+V GERL F VL RV P+G+GLALG +GFG IATFITLYY Sbjct: 190 IVLLGALGFALAWPKLPAPLVHGERLPFHHVLGRVTPHGMGLALGAIGFGTIATFITLYY 249 Query: 281 ASHQWSNAAFSLTLFGGCFIGSRLLFANSINRFGGFKVAIASFIVEAFGLSILWLAGSAE 340 AS W+NA L+ FGGCFIG+RLLFANSINR GGF+VAI VE+ GL +LW A + Sbjct: 250 ASRGWANAVLCLSAFGGCFIGARLLFANSINRLGGFRVAIICLGVESLGLLLLWSAPNPW 309 Query: 341 VAMLGAALAGFGFALVFPSLGVEAVGLVPAPNRGAALGAYSVFLDLALGITGPLAGLIVG 400 V + GAAL GFGF+LVFP+ GVEAV LVPA NRGAALGAYS+F+DL+LGITGPL G + Sbjct: 310 VGLAGAALTGFGFSLVFPAFGVEAVNLVPASNRGAALGAYSLFVDLSLGITGPLVGFVAN 369 Query: 401 QFGYEEVFLFAAIGALCAVALTLSLYRRSQH 431 FG+ +FLFA + +L +AL ++L+RRS+ Sbjct: 370 LFGFRSMFLFACLASLGGLALAVALHRRSRR 400 >yhhS [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 419 Score = 355 bits (911), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 192/387 (49%), Positives = 262/387 (67%) Query: 52 IQILSTVLFTFLAYMTIGIPLAVLPGYVHLDLGYSSFIAGLSISVQYLSTFITRAQAGRM 111 ++I+S V+F F +Y+TIG+PLAVLPGYVH +G+S+F AGL IS+QY +T ++R AGR Sbjct: 31 LRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRY 90 Query: 112 VDTIGPKKTVMRGMLACVASGAFLVLAAWSAELPWLSLSMILVSRFCLGIGESLAGTGSI 171 D++GPKK V+ G+ C SG + A +A LP +SL ++ + R LGIG+S AGTGS Sbjct: 91 ADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGST 150 Query: 172 IWGIGRIGATHTARMISWNGIATYGALAIGAPLGVALLHVGGFAAIGFLALALPLIGYVI 231 +WG+G +G+ H R+ISWNGI TYGA+A+GAPLGV H GG A+ + + + L+ ++ Sbjct: 151 LWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILL 210 Query: 232 ARRRPAVPVVRGERLAFRLVLNRVLPYGIGLALGTVGFGAIATFITLYYASHQWSNAAFS 291 A RP V +G+ L FR VL RV YG+ LAL + GFG IATFITL+Y + W AAF+ Sbjct: 211 AIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFA 270 Query: 292 LTLFGGCFIGSRLLFANSINRFGGFKVAIASFIVEAFGLSILWLAGSAEVAMLGAALAGF 351 LTLF F+G+RLLF N INR GG VA+ F VE GL ++ +A +A +G LAG Sbjct: 271 LTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGA 330 Query: 352 GFALVFPSLGVEAVGLVPAPNRGAALGAYSVFLDLALGITGPLAGLIVGQFGYEEVFLFA 411 GF+LVFP+LGV AV VP N+GAAL Y+VF+DL+LG+TGPLAGL++ G ++L A Sbjct: 331 GFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAA 390 Query: 412 AIGALCAVALTLSLYRRSQHYKTDNAN 438 A A+ LT L +R + + A+ Sbjct: 391 AGLVAIALLLTWRLKKRPPEHVPEAAS 417 >ZyhhS [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 419 Score = 352 bits (903), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 192/387 (49%), Positives = 259/387 (66%) Query: 52 IQILSTVLFTFLAYMTIGIPLAVLPGYVHLDLGYSSFIAGLSISVQYLSTFITRAQAGRM 111 ++ILS V+F F +Y+TIG+PLAVLPGYVH +G+S+F AGL IS+QY +T ++R AGR Sbjct: 31 LRILSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRY 90 Query: 112 VDTIGPKKTVMRGMLACVASGAFLVLAAWSAELPWLSLSMILVSRFCLGIGESLAGTGSI 171 D +GPKK V+ G+ C SG + A +A LP +SL ++ + R LGIG+S AGTGS Sbjct: 91 ADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGST 150 Query: 172 IWGIGRIGATHTARMISWNGIATYGALAIGAPLGVALLHVGGFAAIGFLALALPLIGYVI 231 +WG+G +G+ H R+ISWN I TYGA+A+GAPLGV H GG A+ + + + L+ ++ Sbjct: 151 LWGVGVVGSLHIGRVISWNDIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILL 210 Query: 232 ARRRPAVPVVRGERLAFRLVLNRVLPYGIGLALGTVGFGAIATFITLYYASHQWSNAAFS 291 A RP V +G+ L FR VL RV YG+ LAL + GFG IATFITL+Y W AAF+ Sbjct: 211 AIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDVKGWDGAAFA 270 Query: 292 LTLFGGCFIGSRLLFANSINRFGGFKVAIASFIVEAFGLSILWLAGSAEVAMLGAALAGF 351 LTLF F+G+RLLF N INR GG VA+ F VE GL ++ +A +A +G LAG Sbjct: 271 LTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGA 330 Query: 352 GFALVFPSLGVEAVGLVPAPNRGAALGAYSVFLDLALGITGPLAGLIVGQFGYEEVFLFA 411 GF+LVFP+LGV AV VP N+GAAL Y+VF+DL+LG+TGPLAGL++ G ++L A Sbjct: 331 GFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAA 390 Query: 412 AIGALCAVALTLSLYRRSQHYKTDNAN 438 A A+ LT L +R + + A+ Sbjct: 391 AGLVAIALLLTWRLKKRPPEHVPEAAS 417 >ECs4322 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 419 Score = 352 bits (903), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 192/387 (49%), Positives = 259/387 (66%) Query: 52 IQILSTVLFTFLAYMTIGIPLAVLPGYVHLDLGYSSFIAGLSISVQYLSTFITRAQAGRM 111 ++ILS V+F F +Y+TIG+PLAVLPGYVH +G+S+F AGL IS+QY +T ++R AGR Sbjct: 31 LRILSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRY 90 Query: 112 VDTIGPKKTVMRGMLACVASGAFLVLAAWSAELPWLSLSMILVSRFCLGIGESLAGTGSI 171 D +GPKK V+ G+ C SG + A +A LP +SL ++ + R LGIG+S AGTGS Sbjct: 91 ADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGST 150 Query: 172 IWGIGRIGATHTARMISWNGIATYGALAIGAPLGVALLHVGGFAAIGFLALALPLIGYVI 231 +WG+G +G+ H R+ISWN I TYGA+A+GAPLGV H GG A+ + + + L+ ++ Sbjct: 151 LWGVGVVGSLHIGRVISWNDIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILL 210 Query: 232 ARRRPAVPVVRGERLAFRLVLNRVLPYGIGLALGTVGFGAIATFITLYYASHQWSNAAFS 291 A RP V +G+ L FR VL RV YG+ LAL + GFG IATFITL+Y W AAF+ Sbjct: 211 AIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDVKGWDGAAFA 270 Query: 292 LTLFGGCFIGSRLLFANSINRFGGFKVAIASFIVEAFGLSILWLAGSAEVAMLGAALAGF 351 LTLF F+G+RLLF N INR GG VA+ F VE GL ++ +A +A +G LAG Sbjct: 271 LTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGA 330 Query: 352 GFALVFPSLGVEAVGLVPAPNRGAALGAYSVFLDLALGITGPLAGLIVGQFGYEEVFLFA 411 GF+LVFP+LGV AV VP N+GAAL Y+VF+DL+LG+TGPLAGL++ G ++L A Sbjct: 331 GFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAA 390 Query: 412 AIGALCAVALTLSLYRRSQHYKTDNAN 438 A A+ LT L +R + + A+ Sbjct: 391 AGLVAIALLLTWRLKKRPPEHVPEAAS 417 >STM3581 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 419 Score = 332 bits (852), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 187/387 (48%), Positives = 256/387 (66%) Query: 52 IQILSTVLFTFLAYMTIGIPLAVLPGYVHLDLGYSSFIAGLSISVQYLSTFITRAQAGRM 111 ++I+S V+F F +Y+TIG+PLAVLPGYVH +G+S+F AGL IS+QY +T ++R AGR Sbjct: 31 LRIVSIVMFNFASYLTIGLPLAVLPGYVHDAMGFSAFWAGLIISLQYFATLLSRPHAGRY 90 Query: 112 VDTIGPKKTVMRGMLACVASGAFLVLAAWSAELPWLSLSMILVSRFCLGIGESLAGTGSI 171 D +GPKK V+ G+ C SG +LA ++ P +SL ++ + R LGIG+S AGTGS Sbjct: 91 ADVLGPKKIVVFGLCGCFLSGLGYLLADIASAWPMISLLLLGLGRVILGIGQSFAGTGST 150 Query: 172 IWGIGRIGATHTARMISWNGIATYGALAIGAPLGVALLHVGGFAAIGFLALALPLIGYVI 231 +WG+G +G+ H R+ISWNGI TYGA+A+GAPLGV GG + + + L+ ++ Sbjct: 151 LWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVLCYAWGGLQGLALTVMGVALLAVLL 210 Query: 232 ARRRPAVPVVRGERLAFRLVLNRVLPYGIGLALGTVGFGAIATFITLYYASHQWSNAAFS 291 A RP+V +G+ L FR VL RV YG+ LAL + GFG IATFITL+Y + W AAF+ Sbjct: 211 ALPRPSVKANKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFA 270 Query: 292 LTLFGGCFIGSRLLFANSINRFGGFKVAIASFIVEAFGLSILWLAGSAEVAMLGAALAGF 351 LTLF F+G+RLLF N INR GG VA+ F VE GL ++ A +A +G L G Sbjct: 271 LTLFSVAFVGTRLLFPNGINRLGGLNVAMICFGVEIIGLLLVGTAAMPWMAKIGVLLTGM 330 Query: 352 GFALVFPSLGVEAVGLVPAPNRGAALGAYSVFLDLALGITGPLAGLIVGQFGYEEVFLFA 411 GF+LVFP+LGV AV VP N+GAAL Y+VF+D++LG+TGPLAGL++ G ++L A Sbjct: 331 GFSLVFPALGVVAVKAVPPQNQGAALATYTVFMDMSLGVTGPLAGLVMTWAGVPVIYLAA 390 Query: 412 AIGALCAVALTLSLYRRSQHYKTDNAN 438 A A+ LT L +R + A+ Sbjct: 391 AGLVAMALLLTWRLKKRPPSALPEAAS 417