BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0102.p (293 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 106 5e-23 SA2300 [GEPR] COG0477 Permeases of the major facilitator superfa... 102 1e-21 STM1543 [GEPR] COG0477 Permeases of the major facilitator superf... 97 3e-20 BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superf... 96 1e-19 BMEI0104 [GEPR] COG0477 Permeases of the major facilitator super... 91 2e-18 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 106 bits (265), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 76/300 (25%), Positives = 143/300 (47%), Gaps = 34/300 (11%) Query: 1 VQGITHSFSRLGNAVAPPIVALLIVLHSWRAAFIIVGALTALWIIAWAVYYKDNPREHKA 60 V I S S+LG+A+A P++A L+V W+ F + G+L +W + WA+ ++D+P EH+ Sbjct: 141 VAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVVWALVFRDSPAEHEG 200 Query: 61 INEAELARLPEHVKVTANGGDT---PWKKIL--RRMSPTIFVYFCQVWTNTLFFSWVPIF 115 +N AELA + + + A G D PW K+L R + +F + + F +W+P + Sbjct: 201 VNAAELAHIQKGLP-PARGADAPAMPWTKLLTHRNVWAMCIGFFMINYNSYFFITWLPTY 259 Query: 116 FMNAYHLDIKKSAIFASGVFFAGVVGDVTGGLISDKVLKKTGSLPMARQGVIAFSLLGTL 175 + + + + AS F + +V G SD+V G ++ + L Sbjct: 260 LVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRVYA---------SGRLSLTATRKL 310 Query: 176 CFLVPVMLSHDVNVVAWCLSGAFFMLELTIGP---------IWAVPMDVAPEYT-GTASG 225 ++ ++++ + + A+ S ++ L I +WA+P DVAP T +G Sbjct: 311 FLVIGLVMASSIGLAAFAQSAVVAVILLCIAKSGTTVAASQVWALPADVAPGNTVSMVAG 370 Query: 226 MLNTGAALATIISPVVFGTVIDLTGNWNLPFVGSAVFL---------LIGAVMALKMRPD 276 + N+ + + ++ P+V G ++ TG++ V SA + L+G V + P+ Sbjct: 371 LQNSVSNMGGVVGPIVTGAIVGATGSFIPALVFSAALIGLAILNYLFLLGKVEPIAFEPN 430 >SA2300 [GEPR] COG0477 Permeases of the major facilitator superfamily Sau Staphylococcus aureus N315 Length = 425 Score = 102 bits (254), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/275 (28%), Positives = 137/275 (49%), Gaps = 11/275 (4%) Query: 9 SRLGNAVAPPIVALLIVLHSWRAAFIIVGALTALWIIAWAVYYKDNPREHKAINEAELAR 68 S G +AP + ++ +W+A F I GA+ L + WA+ KD P +H+ +NEAE Sbjct: 144 SYFGPVLAPIVTIAIVNAFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRF 203 Query: 69 LPEHVKVTANGGDT-PWKKILRRMS--PTIFVYFCQVWTNTLFFSWVPIFFMNAYHLDIK 125 + E+ + A + PW +R S YF + TLF W+P + +H++ K Sbjct: 204 IMENRDIVATEKSSPPWNNFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFK 263 Query: 126 KSAIFASGVFFAGVVGDVTGGLISDKVLKKTGSLPMARQGVIAFSLLGTLCFLVPVML-- 183 + +I +S + ++ G ISD+VL S +AR GVIA + G + F V ++ Sbjct: 264 EMSI-SSLPWLLMFFLILSAGAISDRVLGLGRSKFVAR-GVIAIA--GFIVFAVSIIFAV 319 Query: 184 -SHDVNVVAWCLSGAFFMLELTIGPIWAVPMDVAPEYTGTASGMLNTGAALATIISPVVF 242 + ++ V + LS + +++G WA D+ ++GT SG +N + +ISP++ Sbjct: 320 RTGNLYVSIFWLSLGLGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLA 379 Query: 243 GTVIDLTGNWNLPFVGSAVFLLIGAVMALKMRPDR 277 G ++ G W + F V +I +M ++PD+ Sbjct: 380 GLFVEHLG-WTMTFQLLIVPAVIAVIMWFYVKPDQ 413 >STM1543 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 428 Score = 97.4 bits (241), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 82/299 (27%), Positives = 137/299 (45%), Gaps = 26/299 (8%) Query: 3 GITHSFSRLGNAVAPPIVALLIVLHSWRAAFIIVGALTALWIIAWAVYYKDNPREHKAIN 62 GI + S LG AV+ PIV LL + WR AF I+ +W++ W D P K + Sbjct: 136 GIFSAGSPLGGAVSGPIVGLLALSLGWRPAFGIIFLFGLVWVLLWYFIVSDKPTMSKRLA 195 Query: 63 EAELARLPEHVKVTANGGDTPWKKILRRMSPTIFVYFCQ--VWTNTL-----------FF 109 E H V + R +P++ Y Q VW TL F Sbjct: 196 PEERIDFENHEDVILSDDG--------RATPSLGYYMKQPMVWATTLAFFSYNYILFFFL 247 Query: 110 SWVPIFFMNAYHLDIKKSAIFASGVFFAGVVGDVTGGLISDKVLKKTGSLPMARQGVIAF 169 +W P + ++ HLDIK+ +I + G +G V GG+ SD + + TG+ ++R+ ++ Sbjct: 248 TWFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALLSRRLILGV 307 Query: 170 SLLG-TLCFLVPVMLSHDVNVVAWCLSGAFFMLELTIGPI-WAVPMDVA-PEYTGTASGM 226 L G +C V +S + + +S + F+L LT GPI WAV DV + G+ G Sbjct: 308 CLAGAAVCVAVSGTVSTIGSAIT-LMSVSLFLLYLT-GPIYWAVIQDVVHKDKVGSVGGA 365 Query: 227 LNTGAALATIISPVVFGTVIDLTGNWNLPFVGSAVFLLIGAVMALKMRPDRDIHFFEHQ 285 ++ A ++ II P+V G ++ +G ++ F + ++ +++ + E Q Sbjct: 366 MHGLANISGIIGPLVTGFIVQFSGKYDYAFYLAGAIAIVSSLLVFVFVKSKGFKANESQ 424 >BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 455 Score = 95.5 bits (236), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 87/295 (29%), Positives = 141/295 (47%), Gaps = 26/295 (8%) Query: 17 PPIVALLIVLHSWRAAFIIVGALTALWIIAW--AVYYKDNPREHKAINEAELARLPE--- 71 PP++ L W + F+++G L + W VY P++H +NEAELA + + Sbjct: 167 PPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKTVY---EPKKHPKVNEAELAYIEQGGG 223 Query: 72 --HVKVTANGGDT----PWKKILRRMSPTIFVYFCQVWTNTL---FFSWVPIFFMNAYHL 122 + + + +T P+ K L I VY Q TL F +W P++ + A + Sbjct: 224 LISMDDSKSKQETESKWPYIKQLLTNRMLIGVYIAQYCITTLTYFFLTWFPVYLVQARGM 283 Query: 123 DIKKSAIFASGVFFAGVVGDVTGGLISDKVLKKTGSLPMARQ-GVIAFSLLGTLCFLVPV 181 I ++ AS G G V GG++SD +LKK SL AR+ +IA LL C ++ Sbjct: 284 SILEAGFVASLPALCGFAGGVLGGIVSDILLKKGRSLTFARKVPIIAGMLLS--CSMIVC 341 Query: 182 MLSHDVNVVAWCLSGAFFMLELTIGPI-WAVPMDVAP-EYTGTASGMLNTGAALATIISP 239 + +V +S AFF G + WAV D +P E G + G+ NT +A+I +P Sbjct: 342 NYTDSAWLVVVIMSLAFF--GKGFGALGWAVVSDTSPKECAGLSGGLFNTFGNIASITTP 399 Query: 240 VVFGTVIDLTGNWN--LPFVGSAVFLLIGAVMALKMRPDRDIHFFEHQHDGRKLP 292 ++ G +++ TG++N L FVG+ I + + L R + + Q + LP Sbjct: 400 IIIGYIVNATGSFNGALVFVGANAIAAILSYLLLVGPIKRVVLKKQEQDPDQSLP 454 >BMEI0104 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 455 Score = 91.3 bits (225), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 77/274 (28%), Positives = 134/274 (48%), Gaps = 15/274 (5%) Query: 16 APPIVALLIVLHSWRAAFIIVGALTALWIIAWAVYYKDNPREHKAINEAELARLPEHVKV 75 AP V LL+V SWR+ +I++GAL + I+ ++ Y + P +H ++E E+ + +V Sbjct: 187 APIAVGLLLVTGSWRSMYIVLGALGLILIVIFSRIYTNRPEDHPKVSEEEVRLIRAGGEV 246 Query: 76 TANGGDTPWKKILRRMSPTIFV-----YFCQVWTNTLFFSWVPIFFMNAYHLDIKKSAIF 130 ++ + + +S V YF + N + +W P + + + L + Sbjct: 247 QSSSAKSHGFDLKGFISNKTLVFNSIGYFAFQYVNFMILTWTPKYLSDEFGLTLSSLWYM 306 Query: 131 ASGVFFAGVVGDVTGGLISDKVLKKTGSLPMARQGVIAFSLLGTLCFLVPVMLSHDVNVV 190 + V + GG ISD + KTG L +AR G+ A SL T L +M+ H + Sbjct: 307 GMVPWVGACVTILLGGKISDWLFLKTGKLRLARGGLAAASLAITTAVL--LMIPHAGS-- 362 Query: 191 AWCLSGAFFMLE----LTIGPIWAVPMDVAP-EYTGTASGMLNTGAALATIISPVVFGTV 245 AW + G + L WAV +D +P + GT SG+ + A +ATI+SP + G + Sbjct: 363 AWGVIGLMTLANACNSLPNSVYWAVIIDSSPTDKMGTYSGITHFIANIATILSPTLAG-I 421 Query: 246 IDLTGNWNLPFVGSAVFLLIGAVMALKMRPDRDI 279 + ++ +N FV +AV IG + L ++P + + Sbjct: 422 LAMSYGYNAMFVATAVATAIGMIAMLSVKPGQRV 455