BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0086.p (351 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0500 [L] COG2255 Holliday junction resolvasome, helicase subu... 601 e-172 NMA1412 [L] COG2255 Holliday junction resolvasome, helicase subu... 519 e-147 NMB1243 [L] COG2255 Holliday junction resolvasome, helicase subu... 518 e-147 VC1845 [L] COG2255 Holliday junction resolvasome, helicase subun... 483 e-136 YPO2058 [L] COG2255 Holliday junction resolvasome, helicase subu... 478 e-134 >RSc0500 [L] COG2255 Holliday junction resolvasome, helicase subunit Rso Ralstonia solanacearum Length = 357 Score = 601 bits (1549), Expect = e-172, Method: Compositional matrix adjust. Identities = 302/352 (85%), Positives = 324/352 (92%), Gaps = 5/352 (1%) Query: 3 IQTDDF-----SEQRIIAATPASANEEAIERALRPKQLDEYVGQEKVRGQLEIFISAARQ 57 I+TD S +R+I+A+PAS NEEA ERALRPK LDEYVGQEKVRGQL+IF++AA++ Sbjct: 2 IETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAKK 61 Query: 58 RGEALDHTLLFGPPGLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVL 117 R EALDH LLFGPPGLGKTT+AHIIAREMGVNLRQTSGPVLER GDLAALLTNLEANDVL Sbjct: 62 RREALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDVL 121 Query: 118 FIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNP 177 FIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSV+LDLQPFTLVGATTRAGMLTNP Sbjct: 122 FIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNP 181 Query: 178 LRDRFGIVARLEFYTPPELARIVTRSAGLLNAPIVEEGALEIAKRSRGTPRIANRLLRRV 237 LRDRFGIVARLEFYTP ELARIVTRSAGLL+A I E+GALEIAKRSRGTPRIANRLLRRV Sbjct: 182 LRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRRV 241 Query: 238 RDYAEVKGNGRITQAMADAALVMLDVDPVGFDVMDRKLLEAVLFKFNGGPVGLDNLAAAI 297 RDYAEVK +G IT+A+ADAAL MLDVD VGFD+MDRKLLEA+L KFNGGPVG+DNLAAAI Sbjct: 242 RDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAAI 301 Query: 298 GEERDTIEDVLEPYLIQQGYLQRTPRGRVATPLAYTHFGVTAPRTGPNGDLW 349 GEERDTIEDVLEPYLIQQGYLQRTPRGRVAT AY HFG+ AP+TGP DLW Sbjct: 302 GEERDTIEDVLEPYLIQQGYLQRTPRGRVATASAYQHFGLGAPKTGPARDLW 353 >NMA1412 [L] COG2255 Holliday junction resolvasome, helicase subunit NmA Neisseria meningitidis Z2491 Length = 343 Score = 519 bits (1337), Expect = e-147, Method: Compositional matrix adjust. Identities = 262/338 (77%), Positives = 293/338 (86%), Gaps = 3/338 (0%) Query: 3 IQTDDFSE---QRIIAATPASANEEAIERALRPKQLDEYVGQEKVRGQLEIFISAARQRG 59 +QTD+ + QRI+AA ASA EE +ERALRPK LD+Y+GQ K + QL IFI AA++RG Sbjct: 2 LQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQHKAKEQLAIFIQAAKKRG 61 Query: 60 EALDHTLLFGPPGLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFI 119 EALDH LLFGPPGLGKTT+AHIIA+E+GVNLRQTSGPVLERAGDLAALLTNL+ +DVLFI Sbjct: 62 EALDHVLLFGPPGLGKTTLAHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFI 121 Query: 120 DEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLR 179 DEIHRLSPVVEEILYPALEDY++DIMIGEGPAARSV++DL PFTLVGATTRAGMLTNPLR Sbjct: 122 DEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKIDLPPFTLVGATTRAGMLTNPLR 181 Query: 180 DRFGIVARLEFYTPPELARIVTRSAGLLNAPIVEEGALEIAKRSRGTPRIANRLLRRVRD 239 DRFGIV+RLEFY +LA IV+RSA LL + EEGA EIAKRSRGTPRIANRLLRRVRD Sbjct: 182 DRFGIVSRLEFYENRDLATIVSRSAQLLQLDMSEEGAEEIAKRSRGTPRIANRLLRRVRD 241 Query: 240 YAEVKGNGRITQAMADAALVMLDVDPVGFDVMDRKLLEAVLFKFNGGPVGLDNLAAAIGE 299 +A+VK NG I +ADAAL MLDVD G DVMDRK LEAVL KF GGPVGLDN+AAAIGE Sbjct: 242 FADVKNNGTIDGGIADAALSMLDVDVQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGE 301 Query: 300 ERDTIEDVLEPYLIQQGYLQRTPRGRVATPLAYTHFGV 337 DTIEDV+EPYLIQQG+LQRTPRGR+AT AY HFG+ Sbjct: 302 STDTIEDVIEPYLIQQGFLQRTPRGRMATERAYLHFGL 339 >NMB1243 [L] COG2255 Holliday junction resolvasome, helicase subunit Nme Neisseria meningitidis MC58 Length = 343 Score = 518 bits (1334), Expect = e-147, Method: Compositional matrix adjust. Identities = 260/338 (76%), Positives = 293/338 (86%), Gaps = 3/338 (0%) Query: 3 IQTDDFSE---QRIIAATPASANEEAIERALRPKQLDEYVGQEKVRGQLEIFISAARQRG 59 +QTD+ + QRI+AA ASA EE +ERALRPK LD+Y+GQ+K + QL IFI AA++RG Sbjct: 2 LQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQDKAKEQLAIFIQAAKKRG 61 Query: 60 EALDHTLLFGPPGLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFI 119 EALDH LLFGPPGLGKTT+AHIIA+E+GVNLRQTSGPVLERAGDLAALLTNL+ +DVLFI Sbjct: 62 EALDHVLLFGPPGLGKTTLAHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFI 121 Query: 120 DEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLR 179 DEIHRLSPVVEEILYPALEDY++DIMIGEGPAARSV++DL PFTL+GATTRAGMLTNPLR Sbjct: 122 DEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKIDLPPFTLIGATTRAGMLTNPLR 181 Query: 180 DRFGIVARLEFYTPPELARIVTRSAGLLNAPIVEEGALEIAKRSRGTPRIANRLLRRVRD 239 DRFGIV+RLEFY +L IV+RSA LL + EEGA EIAKRSRGTPRIANRLLRRVRD Sbjct: 182 DRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMSEEGAEEIAKRSRGTPRIANRLLRRVRD 241 Query: 240 YAEVKGNGRITQAMADAALVMLDVDPVGFDVMDRKLLEAVLFKFNGGPVGLDNLAAAIGE 299 +A+VK NG I +ADAAL MLDVD G DVMDRK LEAVL KF GGPVGLDN+AAAIGE Sbjct: 242 FADVKNNGTIDGGIADAALSMLDVDAQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGE 301 Query: 300 ERDTIEDVLEPYLIQQGYLQRTPRGRVATPLAYTHFGV 337 DTIEDV+EPYLIQQG+LQRTPRGR+AT AY HFG+ Sbjct: 302 STDTIEDVIEPYLIQQGFLQRTPRGRMATERAYLHFGL 339 >VC1845 [L] COG2255 Holliday junction resolvasome, helicase subunit Vch Vibrio cholerae Length = 334 Score = 483 bits (1243), Expect = e-136, Method: Compositional matrix adjust. Identities = 235/316 (74%), Positives = 273/316 (86%) Query: 22 NEEAIERALRPKQLDEYVGQEKVRGQLEIFISAARQRGEALDHTLLFGPPGLGKTTMAHI 81 +EE I+RA+RPK+L +Y GQ+ VR Q+EIFI AA+ R EALDH L+FGPPGLGKTT+A+I Sbjct: 17 DEEVIDRAIRPKKLADYQGQDHVRDQMEIFIQAAQMRQEALDHLLIFGPPGLGKTTLANI 76 Query: 82 IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQ 141 +A EMGVN+R TSGPVLE+AGDLAALLTNLE NDVLFIDEIHRLSP+VEE+LYPA+EDYQ Sbjct: 77 VANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQ 136 Query: 142 IDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPPELARIVT 201 +DIMIGEGPAARS+++DL PFTL+GATTRAG LT+PLRDRFGIV RLE+Y +L IV Sbjct: 137 LDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEYYKVADLQHIVQ 196 Query: 202 RSAGLLNAPIVEEGALEIAKRSRGTPRIANRLLRRVRDYAEVKGNGRITQAMADAALVML 261 RSA L + EGALE+A+R+RGTPRIANRLLRRVRDYAEVKG+G I AD AL ML Sbjct: 197 RSAQCLGLSMDSEGALEVARRARGTPRIANRLLRRVRDYAEVKGDGHICAQTADRALNML 256 Query: 262 DVDPVGFDVMDRKLLEAVLFKFNGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGYLQRT 321 DVD GFD MDRKLL A++ KF+GGPVG+DNLAAAIGEE+DTIEDVLEP+LIQQGYLQRT Sbjct: 257 DVDHQGFDYMDRKLLLAIMEKFSGGPVGIDNLAAAIGEEKDTIEDVLEPFLIQQGYLQRT 316 Query: 322 PRGRVATPLAYTHFGV 337 PRGR+AT AY HFG+ Sbjct: 317 PRGRIATDRAYLHFGI 332 >YPO2058 [L] COG2255 Holliday junction resolvasome, helicase subunit Ype Yersinia pestis Length = 334 Score = 478 bits (1229), Expect = e-134, Method: Compositional matrix adjust. Identities = 240/327 (73%), Positives = 279/327 (85%), Gaps = 1/327 (0%) Query: 12 RIIAATPASANEEAIERALRPKQLDEYVGQEKVRGQLEIFISAARQRGEALDHTLLFGPP 71 R+I+A + +EE+I+RA+RPK L EYVGQ VR Q+EIFI AA+QRG+ALDH L+FGPP Sbjct: 6 RLISAAVIN-DEESIDRAIRPKLLTEYVGQPHVREQMEIFIQAAKQRGDALDHVLIFGPP 64 Query: 72 GLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEE 131 GLGKTT+A+IIA EMGVNLR TSGPVLE+AGDLAA+LTNLE +DVLFIDEIHRLSPVVEE Sbjct: 65 GLGKTTLANIIANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEE 124 Query: 132 ILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFY 191 ILYPA+EDYQ+DIMIGEGPAARS++LDL PFTL+GATTRAG LT+PLRDRFGIV RLEFY Sbjct: 125 ILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFY 184 Query: 192 TPPELARIVTRSAGLLNAPIVEEGALEIAKRSRGTPRIANRLLRRVRDYAEVKGNGRITQ 251 +L IV+RSA L + EGA ++A+RSRGTPRI NRLLRRVRD+AEV+ +G I Sbjct: 185 QVADLEHIVSRSAKCLGLELTPEGAHQLARRSRGTPRITNRLLRRVRDFAEVRADGAING 244 Query: 252 AMADAALVMLDVDPVGFDVMDRKLLEAVLFKFNGGPVGLDNLAAAIGEERDTIEDVLEPY 311 +A AL ML+VD GFD MDRKLL AV+ KF GGPVGLDNLAAAIGEER+TIEDVLEPY Sbjct: 245 EVAMKALDMLNVDAEGFDFMDRKLLLAVIDKFMGGPVGLDNLAAAIGEERETIEDVLEPY 304 Query: 312 LIQQGYLQRTPRGRVATPLAYTHFGVT 338 LIQQG++QRTPRGR+AT AY HFG+T Sbjct: 305 LIQQGFIQRTPRGRIATNHAYKHFGIT 331