BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0066.p (251 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA2130 [M] COG0744 Membrane carboxypeptidase (penicillin-bindin... 227 2e-59 NMB0357 [M] COG0744 Membrane carboxypeptidase (penicillin-bindin... 226 5e-59 RSc2776 [M] COG0744 Membrane carboxypeptidase (penicillin-bindin... 214 2e-55 PM0324 [M] COG0744 Membrane carboxypeptidase (penicillin-binding... 156 4e-38 CC0325 Non COG 151 1e-36 >NMA2130 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) NmA Neisseria meningitidis Z2491 Length = 233 Score = 227 bits (579), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 108/228 (47%), Positives = 149/228 (65%) Query: 6 KLFLWLIVLPITLLFLLQLYFFVQIWWWVDHNPGSTSFMRHQLSLLQEKNPNAQLQFKWV 65 ++ WLI LP+ + Y + I + P T+FM ++ +++ + L ++W+ Sbjct: 3 RIIKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWM 62 Query: 66 PYNRISNNLKRAIIASEDSNFSEHEGVDWDALQKAYEKNTRKGKVVAGGSTITQQLAKNL 125 PY RIS NLK+A+IASED+ F+ H G DW +Q A +N GKV AGGSTI+QQLAKNL Sbjct: 63 PYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNL 122 Query: 126 FLSGERSYLRKAQEFIITYMLEFLMDKQRIFEIYLNVVEWGNGVFGAEAASLHYYGAPAA 185 FL+ RSY+RK +E IT M+E + DK RIFE+YLN +EW GVFGAEAAS ++Y PAA Sbjct: 123 FLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAA 182 Query: 186 NLGPSQAARLAVMLPRPRFYDKNPGSAYLANRTGLILRRMNAAELPPA 233 L QAA+L +P P +Y +P S L N+T ++LRRM +AELP + Sbjct: 183 KLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLRRMGSAELPES 230 >NMB0357 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) Nme Neisseria meningitidis MC58 Length = 233 Score = 226 bits (575), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 107/228 (46%), Positives = 149/228 (65%) Query: 6 KLFLWLIVLPITLLFLLQLYFFVQIWWWVDHNPGSTSFMRHQLSLLQEKNPNAQLQFKWV 65 ++ WLI LP+ + Y + I + P T+FM ++ +++ + L ++W+ Sbjct: 3 RIIKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWM 62 Query: 66 PYNRISNNLKRAIIASEDSNFSEHEGVDWDALQKAYEKNTRKGKVVAGGSTITQQLAKNL 125 PY RIS NLK+A+IASED+ F+ H G DW +Q A +N GKV AGGSTI+QQLAKNL Sbjct: 63 PYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNL 122 Query: 126 FLSGERSYLRKAQEFIITYMLEFLMDKQRIFEIYLNVVEWGNGVFGAEAASLHYYGAPAA 185 FL+ RSY+RK +E IT M+E + DK RIFE+YLN +EW GVFGAEAAS ++Y PAA Sbjct: 123 FLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAA 182 Query: 186 NLGPSQAARLAVMLPRPRFYDKNPGSAYLANRTGLILRRMNAAELPPA 233 L QAA+L +P P +Y +P S L N+T ++L+RM +AELP + Sbjct: 183 KLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLKRMGSAELPES 230 >RSc2776 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) Rso Ralstonia solanacearum Length = 234 Score = 214 bits (545), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 120/219 (54%), Positives = 148/219 (67%), Gaps = 11/219 (5%) Query: 22 LQLYFFVQIWWWVDHNPGSTSFMR-HQLSLLQEKNPNAQLQFKWVPYNRISNNLKRAIIA 80 L LYFF I W NP S++FMR ++ L + +WVPY++IS NLKRA+IA Sbjct: 19 LNLYFFAAIASWQVFNPASSAFMRAERMRLCGANLVTCGIDHRWVPYDQISRNLKRAVIA 78 Query: 81 SEDSNFSEHEGVDWDALQKAYEKNTRKGKVVAGGSTITQQLAKNLFLSGERSYLRKAQEF 140 SED++F H G + DA+ A+EKN R+G VVAGGSTITQQLAKNLFLSGER YLRK +E Sbjct: 79 SEDADFVSHSGWEVDAMLDAWEKNKRRGHVVAGGSTITQQLAKNLFLSGERHYLRKGEEL 138 Query: 141 IITYMLEFLMDKQRIFEIYLNVVEWGNGVFGAEAASLHYYGAPAANLGPSQAARLAVMLP 200 +IT+MLEF +DK+RI EIYLN VEWG GVFGAEAA+ HY+ PA+ L QAARLA LP Sbjct: 139 VITWMLEFWLDKERILEIYLNSVEWGEGVFGAEAAAQHYFKRPASQLTVGQAARLAAALP 198 Query: 201 RPRFYDKNPGSAYLAN-------RTGLILRRMNAAELPP 232 P+ +DK Y AN + +I RM +A LP Sbjct: 199 APKCFDKKR---YCANVHISFTRKATVIANRMGSATLPD 234 >PM0324 [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) Pmu Pasteurella multocida Length = 246 Score = 156 bits (394), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 93/222 (41%), Positives = 134/222 (60%), Gaps = 8/222 (3%) Query: 5 RKLFLWLIVLPITLLFLLQLYFFVQIWWWVDHNPGSTSFMRHQLSLLQEKNPNAQLQFKW 64 RKL+ + + L + L+ FV + P S ++ ++ L E N ++ + ++W Sbjct: 22 RKLYRTFALFLVLFLSSVVLFRFVPV-------PFSAYMLQQKIGYLFEGNLSSTIHYQW 74 Query: 65 VPYNRISNNLKRAIIASEDSNFSEHEGVDWDALQKAYEKNTRKGKVVAGGSTITQQLAKN 124 VP +IS +++ A+IASED F+ H G DWDA+Q A + N R GK + GGSTI+QQ AKN Sbjct: 75 VPLEQISQSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQR-GKRIRGGSTISQQTAKN 133 Query: 125 LFLSGERSYLRKAQEFIITYMLEFLMDKQRIFEIYLNVVEWGNGVFGAEAASLHYYGAPA 184 L+L +S+LRKA E T +LE L K+RI E+YLN+ E+G +FG EAAS HY+ PA Sbjct: 134 LYLWHGQSWLRKAIEMPTTLVLETLWSKKRILEVYLNIAEFGPNIFGVEAASQHYFRKPA 193 Query: 185 ANLGPSQAARLAVMLPRPRFYDKNPGSAYLANRTGLILRRMN 226 L ++AA LA +LP P + N SAY+ R I R+M Sbjct: 194 KQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMG 235 >CC0325 Non COG Length = 229 Score = 151 bits (381), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 78/168 (46%), Positives = 109/168 (64%), Gaps = 1/168 (0%) Query: 60 LQFKWVPYNRISNNLKRAIIASEDSNFSEHEGVDWDALQKAYEKNTRKGKVVAGGSTITQ 119 L +W P ++IS L R +IA+ED+ F EH G D++ALQKAYE N G+ + GGSTI+Q Sbjct: 52 LDHRWRPMDKISPALPRVLIAAEDAKFCEHRGFDFEALQKAYE-NNESGRKIRGGSTISQ 110 Query: 120 QLAKNLFLSGERSYLRKAQEFIITYMLEFLMDKQRIFEIYLNVVEWGNGVFGAEAASLHY 179 Q AKN+FL RSY+RK E T ++E K+RI E+Y+N +E+G+G++GAEAA+ Y Sbjct: 111 QTAKNVFLWPGRSYVRKGLEAWFTVLIETFWGKKRIMEVYMNSIEYGSGIYGAEAAAQRY 170 Query: 180 YGAPAANLGPSQAARLAVMLPRPRFYDKNPGSAYLANRTGLILRRMNA 227 +G AA L +Q+ARLA +LP P + Y+A RT I + A Sbjct: 171 FGVSAAKLTQAQSARLAAILPSPLKWKVIKPGKYVAKRTKKIGKATGA 218