BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0045.p (329 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2805 [F] COG0209 Ribonucleotide reductase, alpha subunit Rso ... 480 e-135 PA1156 [F] COG0209 Ribonucleotide reductase, alpha subunit Pae P... 405 e-113 CT827 [F] COG0209 Ribonucleotide reductase, alpha subunit Ctr Ch... 346 4e-95 CPn0984 [F] COG0209 Ribonucleotide reductase, alpha subunit Cpn ... 337 3e-92 VNG2384G [F] COG0209 Ribonucleotide reductase, alpha subunit Hbs... 335 1e-91 >RSc2805 [F] COG0209 Ribonucleotide reductase, alpha subunit Rso Ralstonia solanacearum Length = 987 Score = 480 bits (1236), Expect = e-135, Method: Compositional matrix adjust. Identities = 224/265 (84%), Positives = 239/265 (90%), Gaps = 5/265 (1%) Query: 1 MNTANWIPDLFMKRVMEKGEWTLFSPSDAPDLHDKFGKAFEEAYTGYEAKAARGELKLFK 60 MNTANWIPDLFMKRVME GEWTLFSPS PDLHDK GKAFE AY GYE K ARGE+KLFK Sbjct: 479 MNTANWIPDLFMKRVMEGGEWTLFSPSTCPDLHDKVGKAFEAAYLGYEDKVARGEIKLFK 538 Query: 61 KIAALDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIA 120 K+ AL LWRKML MLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTN+SEIA Sbjct: 539 KMPALQLWRKMLGMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNDSEIA 598 Query: 121 VCNLGSVNMPAHLVNG-----EIDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRH 175 VCNLGSVN+ AH+V +DH KL+KT+RTAMRMLDNVIDINYYAVKKARDSNLRH Sbjct: 599 VCNLGSVNLVAHVVKQADGSYALDHDKLKKTVRTAMRMLDNVIDINYYAVKKARDSNLRH 658 Query: 176 RPVGLGIMGFQDCLHMKRVPYASMDAVEFADRSMEAVCYYAYWASTELAEERGRYSSYRG 235 RPVGLGIMGFQD LH+ R+PYA+ AV+FAD SMEAVCYYAYWASTELAEERGRYS+Y+G Sbjct: 659 RPVGLGIMGFQDALHVLRIPYATDAAVQFADTSMEAVCYYAYWASTELAEERGRYSTYKG 718 Query: 236 SLWDRGILPQDSLKLLAQERGGYLE 260 SLWDRG+LPQDSLKLLAQERGGYLE Sbjct: 719 SLWDRGVLPQDSLKLLAQERGGYLE 743 >PA1156 [F] COG0209 Ribonucleotide reductase, alpha subunit Pae Pseudomonas aeruginosa Length = 963 Score = 405 bits (1042), Expect = e-113, Method: Compositional matrix adjust. Identities = 184/261 (70%), Positives = 222/261 (85%), Gaps = 1/261 (0%) Query: 1 MNTANWIPDLFMKRVMEKGEWTLFSPSDAPDLHDKFGKAFEEAYTGYEAKAARGELKLFK 60 MNTANWIPDLFMKRV + G WTLFSPSD PDLHD +GKAFEE Y YEA A+ G+LKL K Sbjct: 481 MNTANWIPDLFMKRVFDDGSWTLFSPSDVPDLHDLYGKAFEERYEYYEALASYGKLKLHK 540 Query: 61 KIAALDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIA 120 + A DLWRKMLSMLFETGHPW+TFKDPCN+RSPQQHVGVVHSSNLCTEITLNTN+ EIA Sbjct: 541 VVQAKDLWRKMLSMLFETGHPWLTFKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIA 600 Query: 121 VCNLGSVNMPAHLVNGEIDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGL 180 VCNLGS+N+ H+V+G++D AKL+KT++TA+RMLDNVIDINYY+V +A++SN +HRPVGL Sbjct: 601 VCNLGSINLVNHIVDGKLDTAKLEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGL 660 Query: 181 GIMGFQDCLHMKRVPYASMDAVEFADRSMEAVCYYAYWASTELAEERGRYSSYRGSLWDR 240 GIMGFQD L+++ +PY S A+ FAD+SMEA+ YYA AS +LA+ERG Y +++GSLW + Sbjct: 661 GIMGFQDALYLQHIPYGSDAAIAFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQ 720 Query: 241 GILPQDSLKLLAQERGG-YLE 260 GILP DS K L +ERG Y+E Sbjct: 721 GILPIDSEKKLIEERGAKYIE 741 >CT827 [F] COG0209 Ribonucleotide reductase, alpha subunit Ctr Chlamydia trachomatis Length = 1047 Score = 346 bits (887), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 159/256 (62%), Positives = 194/256 (75%) Query: 1 MNTANWIPDLFMKRVMEKGEWTLFSPSDAPDLHDKFGKAFEEAYTGYEAKAARGELKLFK 60 +N A+WIPDLF KR+ +KG WTLFSP D P LHD +G+ FE Y YE K GE++LFK Sbjct: 566 VNIASWIPDLFFKRLQQKGTWTLFSPDDVPGLHDAYGEEFERLYEEYERKVDTGEIRLFK 625 Query: 61 KIAALDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIA 120 K+ A DLWRKMLSMLFETGHPW+TFKDP NIRS Q H GVV SNLCTEI LN +E+E A Sbjct: 626 KVEAEDLWRKMLSMLFETGHPWMTFKDPSNIRSAQDHKGVVRCSNLCTEILLNCSETETA 685 Query: 121 VCNLGSVNMPAHLVNGEIDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGL 180 VCNLGS+N+ H+V +D KL +TI A+RMLDNVIDIN+Y K+A+++N HR +GL Sbjct: 686 VCNLGSINLVQHIVGDGLDEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRAIGL 745 Query: 181 GIMGFQDCLHMKRVPYASMDAVEFADRSMEAVCYYAYWASTELAEERGRYSSYRGSLWDR 240 G+MGFQD L+ + YAS +AVEFAD S E + YYA AS LA+ERG YSSY+GS WDR Sbjct: 746 GVMGFQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLAKERGTYSSYKGSKWDR 805 Query: 241 GILPQDSLKLLAQERG 256 G+LP D+++LLA RG Sbjct: 806 GLLPIDTIQLLANYRG 821 >CPn0984 [F] COG0209 Ribonucleotide reductase, alpha subunit Cpn Chlamydophila pneumoniae CWL029 Length = 1044 Score = 337 bits (863), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 154/256 (60%), Positives = 194/256 (75%) Query: 1 MNTANWIPDLFMKRVMEKGEWTLFSPSDAPDLHDKFGKAFEEAYTGYEAKAARGELKLFK 60 +NTA+WIPDLF KR+ +KG WTLFSP D P LH+ +G FE+ Y YE K GE++L+K Sbjct: 564 INTASWIPDLFFKRLEKKGMWTLFSPDDVPGLHEAYGLEFEKLYEEYERKVESGEIRLYK 623 Query: 61 KIAALDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIA 120 K+ A LWRKMLSML+ETGHPWITFKDP NIRS Q HVGVV SNLCTEI LN +ESE A Sbjct: 624 KVEAEVLWRKMLSMLYETGHPWITFKDPSNIRSNQDHVGVVRCSNLCTEILLNCSESETA 683 Query: 121 VCNLGSVNMPAHLVNGEIDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGL 180 VCNLGS+N+ H+ N ++D KL++TI A+R+LDNVID+N+Y +A+ +NL HR VGL Sbjct: 684 VCNLGSINLVEHIRNDKLDEEKLKETISIAIRILDNVIDLNFYPTPEAKQANLTHRAVGL 743 Query: 181 GIMGFQDCLHMKRVPYASMDAVEFADRSMEAVCYYAYWASTELAEERGRYSSYRGSLWDR 240 G+MGFQD L+ + YAS +AVEF+D E + YYA AS+ LA+ERG Y+SY GS WDR Sbjct: 744 GVMGFQDVLYELNISYASQEAVEFSDECSEIIAYYAILASSLLAKERGTYASYSGSKWDR 803 Query: 241 GILPQDSLKLLAQERG 256 G LP D+++LL + RG Sbjct: 804 GYLPLDTIELLKETRG 819 >VNG2384G [F] COG0209 Ribonucleotide reductase, alpha subunit Hbs Halobacterium sp. NRC-1 Length = 804 Score = 335 bits (858), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 153/256 (59%), Positives = 188/256 (73%) Query: 1 MNTANWIPDLFMKRVMEKGEWTLFSPSDAPDLHDKFGKAFEEAYTGYEAKAARGELKLFK 60 MNTA WIPDLFM+RV +WTLFSP + DL++ +G F E Y YEA A G+++ F+ Sbjct: 329 MNTAAWIPDLFMERVRADKQWTLFSPKETGDLYELYGSDFAERYREYEAMADDGDIQRFE 388 Query: 61 KIAALDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIA 120 ++ A DLWR ML+ LFETGHPW+TFKDPCN+RSPQ H G V SSNLCTEITLNT+E E A Sbjct: 389 RVDATDLWRTMLTRLFETGHPWLTFKDPCNVRSPQDHAGTVRSSNLCTEITLNTSEEETA 448 Query: 121 VCNLGSVNMPAHLVNGEIDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGL 180 VCNLGSVN+ HL +G+ID +L +T+ TAMRMLDNV+D+N+Y + A SN+RHRPVGL Sbjct: 449 VCNLGSVNLARHLDDGDIDREQLSETVETAMRMLDNVVDLNFYPTENAERSNMRHRPVGL 508 Query: 181 GIMGFQDCLHMKRVPYASMDAVEFADRSMEAVCYYAYWASTELAEERGRYSSYRGSLWDR 240 G+MGF D L RVP AS DA++ AD E V Y+A AS +LA ERG Y SY GS WDR Sbjct: 509 GVMGFHDALQQMRVPMASDDALDRADALQEYVAYHAIGASADLAAERGTYESYEGSKWDR 568 Query: 241 GILPQDSLKLLAQERG 256 + PQD++ L ERG Sbjct: 569 DVFPQDTVDRLESERG 584