BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0002.p (307 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMa2213 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Si... 327 2e-89 SMa0796 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Si... 305 6e-83 AGl1241 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Ag... 299 5e-81 BH0539 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bac... 272 6e-73 AGpA320 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Ag... 267 2e-71 >SMa2213 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 494 Score = 327 bits (838), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 154/299 (51%), Positives = 209/299 (69%), Gaps = 2/299 (0%) Query: 4 RYQLFINNEWVDPLSGQWFDSLDPFSGEAWAQVPRANKDDVNRAVEAASAAM-EGPWGTM 62 + ++I+ +WV P SG++ +++DPF+ WA VPR N +D +RAV AA A +GPWG M Sbjct: 6 KLSMYIDGQWVAPASGEYIETVDPFTARPWALVPRGNAEDADRAVRAAHRAFSQGPWGKM 65 Query: 63 SATDRGLLLHKLGTLIEKHADTLTLAESRDNGKLKSEVGGQVRYMAKYFYYYGGLADKIQ 122 T+RG ++ + LIE+HAD L E RDNG+L +E+ Q+RY+ ++++YY G ADKI+ Sbjct: 66 HPTERGRIIQRFAALIEEHADALADIEVRDNGRLLAEMTHQIRYIPRWYHYYAGFADKIE 125 Query: 123 GAVIPMDKPKVFNYTRYEPIGVVATITPWNSSLLLTAWKIAPALCAGNTIIAKPSEHTSV 182 G + P DKP +++R+EP+GV I PWN+ LLL + K APAL AGNT++ KP+E TS Sbjct: 126 GTLHPCDKP-ALSFSRHEPLGVCVGIVPWNAPLLLFSLKAAPALAAGNTLVMKPAEFTSA 184 Query: 183 SMFELARLFIEAGFPPGVFNVITGFGAEVGEPLVTHPKVPRIAFTGGDEGGRKVNVLGAQ 242 + +L L +AGFP GV NV+TG+G EVGEPLVTHP + FTG + G + L A+ Sbjct: 185 TALKLMELVEKAGFPTGVINVVTGYGPEVGEPLVTHPLTRHVGFTGSTKTGAHLYSLAAK 244 Query: 243 HFKRVSLELGGKSPHIIFDDADLTRAANGVITGIFSAGGQTCMAGSRLLLQEGIHDEFV 301 KRVSLELGGKSP+I+F DADL A GV+ GIF A GQTC+AGSRLL+ IHDEF+ Sbjct: 245 DVKRVSLELGGKSPNIVFGDADLDNAVRGVVGGIFGAVGQTCIAGSRLLVHRSIHDEFL 303 >SMa0796 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 487 Score = 305 bits (782), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 151/300 (50%), Positives = 201/300 (67%), Gaps = 3/300 (1%) Query: 3 QRYQLFINNEWVDPLSGQWFDSLDPFSGEAWAQVPRANKDDVNRAVEAASAAM-EGPWGT 61 QR+Q +IN E+ D F+S+DP +G AWA++P A + DVNRAVEAA A+ + PW T Sbjct: 2 QRFQCYINGEFAD--GEARFESIDPTTGRAWAEMPEAREADVNRAVEAARIALHDQPWST 59 Query: 62 MSATDRGLLLHKLGTLIEKHADTLTLAESRDNGKLKSEVGGQVRYMAKYFYYYGGLADKI 121 ++AT RG LL+KL L+ ++A L E+RD GK+ E Q+ Y+A Y+ YY G+ADKI Sbjct: 60 LTATQRGKLLYKLADLVAENAGRLAELETRDTGKIIRETSSQIAYVADYYRYYAGIADKI 119 Query: 122 QGAVIPMDKPKVFNYTRYEPIGVVATITPWNSSLLLTAWKIAPALCAGNTIIAKPSEHTS 181 +G+ +P+DKP + + R EPIGVVA + PWNS L L+A KI PAL AG T++ K SE Sbjct: 120 EGSYLPIDKPDMDVWLRREPIGVVAMVVPWNSQLFLSAVKIGPALAAGCTMVVKASEDGP 179 Query: 182 VSMFELARLFIEAGFPPGVFNVITGFGAEVGEPLVTHPKVPRIAFTGGDEGGRKVNVLGA 241 + E ARL AGFP GV N++TGFG G L HP+V IAFTGG E R + A Sbjct: 180 APLLEFARLVHAAGFPAGVVNIVTGFGPSCGAALSRHPQVDHIAFTGGPETARHIVRNSA 239 Query: 242 QHFKRVSLELGGKSPHIIFDDADLTRAANGVITGIFSAGGQTCMAGSRLLLQEGIHDEFV 301 ++ SLELGGKSP I+F DADL AAN I GIF+A GQ+C+AGSRL++++ + D F+ Sbjct: 240 ENLASTSLELGGKSPFIVFADADLESAANAQIAGIFAATGQSCVAGSRLIVEKSVKDRFL 299 >AGl1241 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 493 Score = 299 bits (765), Expect = 5e-81, Method: Compositional matrix adjust. Identities = 148/303 (48%), Positives = 200/303 (66%), Gaps = 4/303 (1%) Query: 1 MTQRYQLFINNEWVDPLSGQWFDSLDPFSGEAWAQVPRANKDDVNRAVEAASAAM--EGP 58 + +R+Q +I+ + D + F SLDP +G+ WA++P + + D+ R VEAA A+ + Sbjct: 5 VMRRFQCYIDGRFEDGEAS--FSSLDPATGQPWAEMPESREADIGRVVEAAHRALYEDTV 62 Query: 59 WGTMSATDRGLLLHKLGTLIEKHADTLTLAESRDNGKLKSEVGGQVRYMAKYFYYYGGLA 118 W ++AT RG LL++L L+ ++A TL E+RD GK+ E Q+ Y+A Y+ YY GLA Sbjct: 63 WSKLTATQRGKLLYRLADLVAENAKTLAELETRDTGKIIRETSAQIAYVADYYRYYAGLA 122 Query: 119 DKIQGAVIPMDKPKVFNYTRYEPIGVVATITPWNSSLLLTAWKIAPALCAGNTIIAKPSE 178 DKI+GA +P+DKP + + R EP+GVVA I PWNS L L A KI PAL AG TI+ K SE Sbjct: 123 DKIEGAYLPIDKPDMDVWLRREPVGVVAAIVPWNSQLFLAAVKIGPALAAGCTIVVKASE 182 Query: 179 HTSVSMFELARLFIEAGFPPGVFNVITGFGAEVGEPLVTHPKVPRIAFTGGDEGGRKVNV 238 + E ARL EAGFP GV NV+TGFGA G L THPKV IAFTGG E R + Sbjct: 183 DGPAPLLEFARLVHEAGFPAGVVNVVTGFGASCGNALTTHPKVAHIAFTGGPETARHIVR 242 Query: 239 LGAQHFKRVSLELGGKSPHIIFDDADLTRAANGVITGIFSAGGQTCMAGSRLLLQEGIHD 298 A++ SLELGGKSP ++F DADL AAN + GIF+A GQ+C+AGSRL++++ + D Sbjct: 243 NSAENLASTSLELGGKSPILVFADADLESAANAQVAGIFAATGQSCVAGSRLIIEKSVKD 302 Query: 299 EFV 301 F+ Sbjct: 303 RFL 305 >BH0539 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bacillus halodurans Length = 498 Score = 272 bits (696), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 140/304 (46%), Positives = 190/304 (62%), Gaps = 3/304 (0%) Query: 6 QLFINNEWVDPLSGQWFDSLDPFSGEAWAQVPRANKDDVNRAVEAASAAM-EGPWGTMSA 64 +LFIN EWVD SGQ F++++P +GE A V A +D++ AV+AA A EGPW MSA Sbjct: 25 KLFINGEWVDSFSGQSFETMNPATGETLALVAEAGSEDIDFAVKAARKAFDEGPWSKMSA 84 Query: 65 TDRGLLLHKLGTLIEKHADTLTLAESRDNGK-LKSEVGGQVRYMAKYFYYYGGLADKIQG 123 +R L++KL LIE H + L E+ DNGK ++ + + ++F Y+ G A KI G Sbjct: 85 AERSRLIYKLADLIEDHKEALAQLETLDNGKPIRETANADIPLVIEHFRYFAGWATKIVG 144 Query: 124 AVIPMDKPKVFNYTRYEPIGVVATITPWNSSLLLTAWKIAPALCAGNTIIAKPSEHTSVS 183 IP+ + FNYTR+E IGVV I PWN LL+ AWK+ AL G T++ KP+E T +S Sbjct: 145 QTIPV-QGHYFNYTRHEAIGVVGQIIPWNFPLLMAAWKLGAALATGCTVVLKPAEQTPLS 203 Query: 184 MFELARLFIEAGFPPGVFNVITGFGAEVGEPLVTHPKVPRIAFTGGDEGGRKVNVLGAQH 243 L L EAGFP GV N++ GFG G PLV HP V ++AFTG + G+ + ++ Sbjct: 204 ALYLGELINEAGFPKGVVNIVPGFGHSAGTPLVNHPAVDKVAFTGSTDVGKLIMKQASES 263 Query: 244 FKRVSLELGGKSPHIIFDDADLTRAANGVITGIFSAGGQTCMAGSRLLLQEGIHDEFVLR 303 KRV+LELGGKSP+II DADL++A G + GI GQ C AGSRL +Q+ +D V Sbjct: 264 LKRVTLELGGKSPNIILPDADLSKAVPGSLMGIMFNQGQVCCAGSRLYVQKKQYDHVVAD 323 Query: 304 TLTL 307 ++L Sbjct: 324 LVSL 327 >AGpA320 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 507 Score = 267 bits (683), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 134/300 (44%), Positives = 190/300 (63%), Gaps = 1/300 (0%) Query: 3 QRYQLFINNEWVDPLSGQWFDSLDPFSGEAWAQVPRANKDDVNRAVEAASAAMEGP-WGT 61 +R LFI+ +V+P SG++ DS DP +GEAW Q DDV+ A+ +A A P W Sbjct: 15 KRLGLFIDGRFVEPRSGKFVDSYDPTTGEAWYQFAEGGADDVDLAISSAQRAFRDPSWRR 74 Query: 62 MSATDRGLLLHKLGTLIEKHADTLTLAESRDNGKLKSEVGGQVRYMAKYFYYYGGLADKI 121 M+ T RG L+ +L L+ +HA+ L L E+RDNGKL E+ Q+R + + Y+ G+ADK+ Sbjct: 75 MTQTARGKLVRRLADLVLEHAEDLALLETRDNGKLIKEMRAQMRAIPDSYLYFAGMADKL 134 Query: 122 QGAVIPMDKPKVFNYTRYEPIGVVATITPWNSSLLLTAWKIAPALCAGNTIIAKPSEHTS 181 QG IP++K N+ EP+GV+ +TPWNS L+L +AP L GNT++ KPSEH + Sbjct: 135 QGDTIPVNKLDQLNFNMREPLGVIGMVTPWNSPLMLLTGTLAPCLAIGNTVVIKPSEHAT 194 Query: 182 VSMFELARLFIEAGFPPGVFNVITGFGAEVGEPLVTHPKVPRIAFTGGDEGGRKVNVLGA 241 S LA L +EAGFP GV NV+TG GA GE L H + + FTG GR++ A Sbjct: 195 ASTLALAELIVEAGFPAGVVNVVTGGGAVTGEALTRHNGIAKFVFTGSTATGRRIAANAA 254 Query: 242 QHFKRVSLELGGKSPHIIFDDADLTRAANGVITGIFSAGGQTCMAGSRLLLQEGIHDEFV 301 + +ELGGKSPH++F D D+ + NGV++G+F+A GQTC+AGSR ++ I+D F+ Sbjct: 255 ANLVPCQMELGGKSPHVVFSDVDIEKTVNGVVSGVFAAAGQTCVAGSRCFVEANIYDRFI 314