BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0095.p (553 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0547 [GEPR] COG0477 Permeases of the major facilitator superf... 755 0.0 PA3709 [GEPR] COG0477 Permeases of the major facilitator superfa... 671 0.0 CC0980 [GEPR] COG0477 Permeases of the major facilitator superfa... 667 0.0 mlr0338 [GEPR] COG0477 Permeases of the major facilitator superf... 663 0.0 SMc04407 [GEPR] COG0477 Permeases of the major facilitator super... 631 e-180 >RSc0547 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 567 Score = 755 bits (1950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/549 (69%), Positives = 456/549 (83%), Gaps = 7/549 (1%) Query: 10 ITPEERKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIV 69 +T EE+KVIFASSLGTVFEWYDFYLYGSLAAIIAKQFF+G DP AFIFALLAFAAGF+V Sbjct: 20 MTREEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFSGLDPTAAFIFALLAFAAGFLV 79 Query: 70 RPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGILPNYNSIGIAAPIILIILRILQG 129 RPFGALVFGRLGD++GRKYTFL+TILIMG STFIVG+LP+Y +IG AAP+ILI+LR+LQG Sbjct: 80 RPFGALVFGRLGDMIGRKYTFLITILIMGTSTFIVGLLPSYTTIGAAAPVILIMLRLLQG 139 Query: 130 LALGGEYGGAATYVAEHAPEGKRGSFTAWIQTTATLGLFLSLLVILGVRTAVGEAAFADW 189 LALGGEYGGAATYVAEHAP G+RG++T+WIQTTATLGLFLSL+VIL VR G A+F DW Sbjct: 140 LALGGEYGGAATYVAEHAPHGRRGNYTSWIQTTATLGLFLSLIVILVVRELTG-ASFEDW 198 Query: 190 GWRIPFLVSIILLGISVWIRLSMNESPAFLKMKSEGKLSKAPLTEAFGKWKNLKLVILAL 249 GWRIPFLVSI+LL SV+IRLSM+ESPAF KMK+EGK SKAPLTE+FG+W+NLK+VILAL Sbjct: 199 GWRIPFLVSIVLLATSVYIRLSMSESPAFQKMKAEGKTSKAPLTESFGQWRNLKIVILAL 258 Query: 250 IGMTAGQAVVWYAGQFYSLFFLTQTLKVDGPLANILIALALLLATPFFLVFGSLSDKIGR 309 +G+TAGQAVVWY GQFY+LFFLTQ LKVD AN+LIA+AL + TPFF+ FGSLSD+IGR Sbjct: 259 VGLTAGQAVVWYTGQFYALFFLTQVLKVDAFTANVLIAVALAIGTPFFVFFGSLSDRIGR 318 Query: 310 KPIILGGCLIAAVTYFPIFQGLTHYANPALEAALKKAPVIVTADPATCQFQFNPTGTK-K 368 K II+ GCL+A +TYFP+F+ LTHYANPALE A + A + + ADP C FQ +P + Sbjct: 319 KGIIMAGCLLAVLTYFPLFKALTHYANPALERAQQTAQITIKADPKECSFQGSPIAREVD 378 Query: 369 FTSSCDIAKAKLSAASVNYENVAGAPGSVATIKIGEKILTSYDAAGLSKE---DASAKDK 425 F SSCDIAK L+ +S +YE+ G++A++ I + + S +A+ + DA +K K Sbjct: 379 FRSSCDIAKRTLAQSSASYESEDAPAGTIASVTIAGREIASLNASRTADGQNFDADSKKK 438 Query: 426 --AFSKELADDIKAAGYPTKADPDQMNKPMVLLLLFILVLYVTMVYGPVAAALVEMFPTR 483 F K ++D +KAA YP+KADP QMN MVL++L ILV+YVTMVYGP+AA LVE+FPTR Sbjct: 439 ITDFKKSVSDALKAANYPSKADPAQMNTVMVLVILVILVIYVTMVYGPIAAMLVELFPTR 498 Query: 484 IRYTSMSMPYHIGNGWFGGLLPTTAFALVAYKGDIYYGLWYPIVIALATFIIGLLFVKES 543 IRYTSMS+PYHIGNGWFGGLLPT +FALVA G+IYYGLWYPI IA TF+IG LFV+E+ Sbjct: 499 IRYTSMSLPYHIGNGWFGGLLPTISFALVAQHGNIYYGLWYPIWIAAITFVIGALFVRET 558 Query: 544 KDNNINAEE 552 KD +I + Sbjct: 559 KDVDIYRHD 567 >PA3709 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 539 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/541 (62%), Positives = 419/541 (77%), Gaps = 17/541 (3%) Query: 9 TITPEERKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFI 68 T EERKVIFASSLGTVFEWYDF+LYG+LAA+I+KQFFAG + TAFIFAL+AFAAGF+ Sbjct: 15 TTPQEERKVIFASSLGTVFEWYDFFLYGALAAVISKQFFAGVNDTTAFIFALMAFAAGFL 74 Query: 69 VRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGILPNYNSIGIAAPIILIILRILQ 128 VRPFGALVFGRLGD++GRKYTFLVTIL+MG STF VG+LP Y SIG+AAPIIL+ LR+LQ Sbjct: 75 VRPFGALVFGRLGDMIGRKYTFLVTILLMGLSTFAVGLLPTYASIGVAAPIILVTLRMLQ 134 Query: 129 GLALGGEYGGAATYVAEHAPEGKRGSFTAWIQTTATLGLFLSLLVILGVRTAVGEAAFAD 188 GLALGGEYGGAA YVAEHAP KRGS+T+WIQ+TATLGL LSLLVIL R G+ F Sbjct: 135 GLALGGEYGGAAIYVAEHAPANKRGSYTSWIQSTATLGLLLSLLVILACRQLTGDE-FET 193 Query: 189 WGWRIPFLVSIILLGISVWIRLSMNESPAFLKMKSEGKLSKAPLTEAFGKWKNLKLVILA 248 WGWR+PFL+SI+LLGIS WIRLSM ESPAFLKMK+EGK+SKAPL E+F +W NLK+V+ A Sbjct: 194 WGWRLPFLLSIVLLGISTWIRLSMRESPAFLKMKAEGKVSKAPLRESFTQWGNLKVVLTA 253 Query: 249 LIGMTAGQAVVWYAGQFYSLFFLTQTLKVDGPLANILIALALLLATPFFLVFGSLSDKIG 308 L + AGQAV +Y QFY LFFLTQ LKVDG AN L+ +AL+L PFF+V G LSD+IG Sbjct: 254 LFSINAGQAVTFYTAQFYVLFFLTQVLKVDGGTANGLLIVALVLGAPFFIVAGWLSDRIG 313 Query: 309 RKPIILGGCLIAAVTYFPIFQGLTHYANPALEAALKKAPVIVTADPATCQFQFNPTGTKK 368 RKP++L G L+A + YFP+F+GLTHYANPA++ A +++P+ V ADPATC FQF+P G Sbjct: 314 RKPVLLAGLLLATLFYFPLFKGLTHYANPAIDQASRQSPISVVADPATCTFQFDPVGKAT 373 Query: 369 FTSSCDIAKAKLSAASVNYENVAGAPGSVATIKIGEKILTSYDAAGLSKEDASAKDKAFS 428 F S CD K L A + Y VA GS ++IGE + +DA Sbjct: 374 FDSPCDKVKTFLVKAGLPYSTVAAPAGSDVRVRIGETEIAGFDA---------------- 417 Query: 429 KELADDIKAAGYPTKADPDQMNKPMVLLLLFILVLYVTMVYGPVAAALVEMFPTRIRYTS 488 + +A +K AGYP +AD Q+NKPMV+ ++F LVL T+ YGP+AA +VE+FPTRIRY+S Sbjct: 418 EAMAAAVKTAGYPQQADGSQVNKPMVIAIIFALVLISTLCYGPLAALMVELFPTRIRYSS 477 Query: 489 MSMPYHIGNGWFGGLLPTTAFALVAYKGDIYYGLWYPIVIALATFIIGLLFVKESKDNNI 548 +S+PYHIGNGWFGG LPT +FALV Y GDI+YGLWYP++I + + LLF++E++ +I Sbjct: 478 LSLPYHIGNGWFGGFLPTVSFALVVYTGDIFYGLWYPVLITGGSLVCALLFLRETRHTDI 537 Query: 549 N 549 + Sbjct: 538 H 538 >CC0980 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 567 Score = 667 bits (1722), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/537 (63%), Positives = 425/537 (79%) Query: 13 EERKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIVRPF 72 + V+ ASSLGTVFEWYDFYLYGSLA II FF+G + T FI ALLAFAAGF +RP Sbjct: 30 RDTMVVGASSLGTVFEWYDFYLYGSLAPIITSHFFSGVNETTGFILALLAFAAGFAIRPL 89 Query: 73 GALVFGRLGDLVGRKYTFLVTILIMGASTFIVGILPNYNSIGIAAPIILIILRILQGLAL 132 GAL+FGRLGDL GRK TFL+T+L+MG STF+VG+LP+Y IG+AAPI L+++R++QGLAL Sbjct: 90 GALIFGRLGDLWGRKNTFLITMLLMGVSTFVVGLLPSYAQIGVAAPIALVLMRLVQGLAL 149 Query: 133 GGEYGGAATYVAEHAPEGKRGSFTAWIQTTATLGLFLSLLVILGVRTAVGEAAFADWGWR 192 GGEYGGAATYVAEHAP GKRG +T+WIQTTAT+GLFLSL VIL R +GE AF WGWR Sbjct: 150 GGEYGGAATYVAEHAPPGKRGFYTSWIQTTATIGLFLSLAVILVARIQLGEEAFKAWGWR 209 Query: 193 IPFLVSIILLGISVWIRLSMNESPAFLKMKSEGKLSKAPLTEAFGKWKNLKLVILALIGM 252 IPFLVS++LLG+S+WIRL ++ESP F +M +EGK SK PLTEAFG W NLK+V+LAL+G+ Sbjct: 210 IPFLVSLLLLGVSLWIRLKLHESPTFERMIAEGKGSKKPLTEAFGNWPNLKIVLLALVGL 269 Query: 253 TAGQAVVWYAGQFYSLFFLTQTLKVDGPLANILIALALLLATPFFLVFGSLSDKIGRKPI 312 T GQAVVWY GQFY+LFFL +TLK+DG LAN L+A+ALL+ TPFF++ G LSDKIGRKPI Sbjct: 270 TMGQAVVWYTGQFYALFFLEKTLKLDGALANTLVAVALLIGTPFFVICGWLSDKIGRKPI 329 Query: 313 ILGGCLIAAVTYFPIFQGLTHYANPALEAALKKAPVIVTADPATCQFQFNPTGTKKFTSS 372 I+ GCL+AA+TYFPIF+ +T YANPAL A APV+VTAD ATC FQF+ G KF + Sbjct: 330 IILGCLLAALTYFPIFKAITTYANPALAKAEATAPVVVTADTATCAFQFDLIGKAKFNTP 389 Query: 373 CDIAKAKLSAASVNYENVAGAPGSVATIKIGEKILTSYDAAGLSKEDASAKDKAFSKELA 432 CD+AKA L+ A V+Y A G+ +K+G+ L D+ G + + + KA+ +L Sbjct: 390 CDVAKAYLAKAGVSYSVQAAPAGTPTAVKVGDVTLEGLDSKGATGQAFADARKAWEADLG 449 Query: 433 DDIKAAGYPTKADPDQMNKPMVLLLLFILVLYVTMVYGPVAAALVEMFPTRIRYTSMSMP 492 +KAAGYP KAD +NKP V+ LL +LV+YVTMVYGP+AA LVE+FPTRIRYT+MS+P Sbjct: 450 AQLKAAGYPAKADAALVNKPAVIGLLALLVIYVTMVYGPIAAMLVELFPTRIRYTAMSLP 509 Query: 493 YHIGNGWFGGLLPTTAFALVAYKGDIYYGLWYPIVIALATFIIGLLFVKESKDNNIN 549 YHIGNGWFGG LPTTAFA+VA GDIY GLWYP++IA T ++G LF+K+++ N + Sbjct: 510 YHIGNGWFGGFLPTTAFAIVAATGDIYSGLWYPVIIAAITAVVGGLFLKDTRHNRLE 566 >mlr0338 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 629 Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/629 (57%), Positives = 439/629 (69%), Gaps = 77/629 (12%) Query: 1 MATASTA----HTITPEERKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPN-TA 55 MA ASTA +T EE+KVIFASSLGTVFEWYDFYLYGSLAA I FF+ T P T Sbjct: 1 MAMASTAGRTSRGMTREEKKVIFASSLGTVFEWYDFYLYGSLAAFIGSTFFSPTIPEATR 60 Query: 56 FIFALLAFAAGFIVRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGILPNYNSIGI 115 IFALLAFAAGF+VRPFGALVFGR+GDLVGRKYTFLVT+ IMG STF+VG+LP Y ++GI Sbjct: 61 NIFALLAFAAGFLVRPFGALVFGRIGDLVGRKYTFLVTMTIMGLSTFLVGLLPGYATLGI 120 Query: 116 AAPIILIILRILQGLALGGEYGGAATYVAEHAPEGKRGSFTAWIQTTATLGLFLSLLVIL 175 AAP+ILI LR+LQGLALGGEYGGAATYVAEHAP+ +RG +T+WIQTTATLGLFLSL+VIL Sbjct: 121 AAPVILIALRMLQGLALGGEYGGAATYVAEHAPDDRRGFYTSWIQTTATLGLFLSLIVIL 180 Query: 176 GVRTAVGEAAFADWGWRIPFLVSIILLGISVWIRLSMNESPAFLKMKSEGKLSKAPLTEA 235 V+ ++ + +A WGWRIPF+VS +LL +S+WIRLS++ESP F KMK EGK SKAPL+EA Sbjct: 181 IVQGSLSKETYAAWGWRIPFIVSFVLLAVSIWIRLSLSESPTFQKMKDEGKGSKAPLSEA 240 Query: 236 FGKWKNLKLVILALIGMTAGQAVVWYAGQFYSLFFLTQTLKVDGPLANILIALALLLATP 295 FG+WKN K+ +LAL+G+TAGQAVVWY GQFY+LFFL LKVD NI+IA+AL L + Sbjct: 241 FGQWKNAKIALLALLGLTAGQAVVWYNGQFYALFFLQNVLKVDAQSVNIMIAIALALGSI 300 Query: 296 FFLVFGSLSDKIGRKPIILGGCLIAAVTYFPIFQGLTHYANPALEAALKKAPVIVTADPA 355 FF+VFG LSDKIGRKPII+ G +A V FP+F+ LT ANPAL A + VTA P Sbjct: 301 FFVVFGWLSDKIGRKPIIMAGLALAIVCTFPLFKALTWAANPALATAQQNTRATVTAAPG 360 Query: 356 TCQFQFNPTGTKKFTSSCDIAKAKLSAASVNYENVA-GAPGSVATIKIGEKILTSY---- 410 C+FQFNP GT KFT+SCDIA + L+ SV ++ V+ A G+ AT+KIG + + SY Sbjct: 361 DCKFQFNPVGTAKFTTSCDIATSFLTKNSVPFDVVSTAAAGTPATVKIGNETVASYDAVA 420 Query: 411 --------DAAGLSKEDASAKD-------------------------------------- 424 DAA + + S KD Sbjct: 421 AGDQAKAKDAAFVKAVNMSLKDGGYPLKRAAIKVADQKLDAFIAANPELKLDAATIRGGE 480 Query: 425 -------KAFSKELADDIKAAGYPTK--------------ADPDQMNKPMVLLLLFILVL 463 +A +L +AAG P ADP +N PM + +LFILVL Sbjct: 481 KATVPTEQAVKDKLVTSEEAAGAPEVTVYNIPGGGAFAMFADPAAVNWPMTIGILFILVL 540 Query: 464 YVTMVYGPVAAALVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTAFALVAYKGDIYYGLW 523 +VTMVYGP+AA LVEMFPTRIRYT MS+PYHIGNGWFGGLLP T FAL AY+GDIY+GLW Sbjct: 541 FVTMVYGPIAAILVEMFPTRIRYTGMSLPYHIGNGWFGGLLPATVFALSAYRGDIYFGLW 600 Query: 524 YPIVIALATFIIGLLFVKESKDNNINAEE 552 YP+VIA T IIG++FVK++ ++ A+E Sbjct: 601 YPVVIAAMTLIIGMIFVKDTLGTDLRAKE 629 >SMc04407 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 629 Score = 631 bits (1627), Expect = e-180, Method: Compositional matrix adjust. Identities = 352/623 (56%), Positives = 416/623 (66%), Gaps = 72/623 (11%) Query: 2 ATASTAHTITPEERKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALL 61 A + A +T EE+KVIFASSLGTVFEWYDFYLYGSLA I FF+ T IFALL Sbjct: 7 AGGTKAGPMTGEEKKVIFASSLGTVFEWYDFYLYGSLAVYIGATFFSQYPETTRNIFALL 66 Query: 62 AFAAGFIVRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGILPNYNSIGIAAPIIL 121 AFAAGF+VRPFGALVFGRLGDLVGRKYTFLVTILIMG STF+VG+LP SIGIAAPIIL Sbjct: 67 AFAAGFLVRPFGALVFGRLGDLVGRKYTFLVTILIMGVSTFLVGVLPGAASIGIAAPIIL 126 Query: 122 IILRILQGLALGGEYGGAATYVAEHAPEGKRGSFTAWIQTTATLGLFLSLLVILGVRTAV 181 I LR+LQGLALGGEYGGAATYVAEHAP G+RG FT+WIQTTATLGLFLSL+VIL V+ + Sbjct: 127 IALRLLQGLALGGEYGGAATYVAEHAPHGRRGYFTSWIQTTATLGLFLSLVVILLVQYML 186 Query: 182 GEAAFADWGWRIPFLVSIILLGISVWIRLSMNESPAFLKMKSEGKLSKAPLTEAFGKWKN 241 G+ AFA+WGWRIPFL+S +LLG+SVWIRL MNESPAF KMK EGK SKAPLTEAFG+W+N Sbjct: 187 GKEAFAEWGWRIPFLLSFVLLGVSVWIRLKMNESPAFKKMKEEGKGSKAPLTEAFGQWRN 246 Query: 242 LKLVILALIGMTAGQAVVWYAGQFYSLFFLTQTLKVDGPLANILIALALLLATPFFLVFG 301 K+ +LAL G GQAVVWY+GQFY+LFFL LKVDG AN+++A +LLL T FF+ FG Sbjct: 247 AKIAVLALFGAVVGQAVVWYSGQFYALFFLQSILKVDGQSANLMVAASLLLGTGFFVFFG 306 Query: 302 SLSDKIGRKPIILGGCLIAAVTYFPIFQGLTHYANPALEAALKKAPVIVT---------- 351 LSDKIGRKPII+ G L+A +TYFP+F+ LT NPAL A + VT Sbjct: 307 WLSDKIGRKPIIMAGLLLAMLTYFPLFKALTWAGNPALAEAQQSVRATVTAAPGDCKFQF 366 Query: 352 -----------ADPATCQFQFNPT------------------GTKKFTS-----SCDIAK 377 D AT N G TS + D AK Sbjct: 367 NPTGTAKFTTSCDIATAFLTKNSVPYDVVTTAAAGTPATVKIGETTITSYDAIAAGDRAK 426 Query: 378 AKLSA--ASVNYE-NVAGAPGSVATIKIGEKILTSYDAA----GLSKEDASAKDKAF--- 427 A+ +A +N +G P K+ E L ++ AA GL A +K Sbjct: 427 AEEAAFGKQINMALQASGYPLVRGAAKVPESKLDAFVAANPELGLDAAAVRAGEKTMVPA 486 Query: 428 SKELADDI------------------KAAGYPTKADPDQMNKPMVLLLLFILVLYVTMVY 469 K +AD + K + ADP ++N +++ +L +LV+YVTMVY Sbjct: 487 DKLVADKLLTQEEVGSATEMAVYNIDKGGAFTMVADPARVNWTVIIAVLTVLVIYVTMVY 546 Query: 470 GPVAAALVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTAFALVAYKGDIYYGLWYPIVIA 529 GP+AA LVE+FPTRIRYT MS+PYHIGNGWFGGLLP TAFA+ A KGDIYYGLWYPIV A Sbjct: 547 GPIAALLVELFPTRIRYTGMSLPYHIGNGWFGGLLPATAFAMSAAKGDIYYGLWYPIVFA 606 Query: 530 LATFIIGLLFVKESKDNNINAEE 552 T +IGLLF+ E+KD +I+ E Sbjct: 607 GITLVIGLLFLPETKDRDIHTME 629