BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0013.p (317 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0193 [Q] COG2175 Probable taurine catabolism dioxygenase Pae P... 395 e-110 Rv3406 [Q] COG2175 Probable taurine catabolism dioxygenase Mtu M... 281 2e-75 MT3514 [Q] COG2175 Probable taurine catabolism dioxygenase MtC M... 281 2e-75 mll5998 Non COG 275 1e-73 PA3935 [Q] COG2175 Probable taurine catabolism dioxygenase Pae P... 175 1e-43 >PA0193 [Q] COG2175 Probable taurine catabolism dioxygenase Pae Pseudomonas aeruginosa Length = 300 Score = 395 bits (1016), Expect = e-110, Method: Compositional matrix adjust. Identities = 192/281 (68%), Positives = 227/281 (80%), Gaps = 1/281 (0%) Query: 6 LNLHPVAGRIGAEIRDVRLSGDLGQETFHAIRQALLKYKVLFFRGQQHLDDVGQEAFAKL 65 L++ PVAGRIGAEIR V LSG+L T AI+ AL+++KV+FFR Q HLDD QEAFA L Sbjct: 14 LDIRPVAGRIGAEIRGVTLSGELDAATVEAIQAALVRHKVIFFRDQSHLDDQTQEAFAHL 73 Query: 66 FGELVAHPTVPVRDGTGYLLELDSVHGGRANSWHTDVTFDLAYPQASILRAVVIPQAGGD 125 GE VAHPTVP R+GT +LLELD G RANSWHTDVTF AYP+ASILR+VV P++GGD Sbjct: 74 LGEPVAHPTVPSREGTRFLLELDGAEGRRANSWHTDVTFVEAYPKASILRSVVAPESGGD 133 Query: 126 TVWANTAQAYLDLPPALRQLADTLWALHTNDYDYAA-RFNTDDAGLKRYREVFTSRIYET 184 TVWANTA AY DLP LR+LAD LWA+H+N+YDYA + + L+ YR+VFTS +YET Sbjct: 134 TVWANTASAYADLPAELRELADRLWAVHSNEYDYAGVKPSASVEQLENYRKVFTSTVYET 193 Query: 185 EHPVVRVHPETGERTLVLGHFVKKLLGYPTGDSEHLLKLLESYVIRLENTVRWRWTAGDI 244 EHPVVRVHP++GERTL+LGHFVK+L G DS HL +L+ +V RLENTVRWRW AGD+ Sbjct: 194 EHPVVRVHPQSGERTLLLGHFVKRLKGLSQHDSAHLFAVLQGHVTRLENTVRWRWQAGDV 253 Query: 245 AIWDNRATQHYAINDYGSQHRVVRRVTIAGDVPVGVDGRRS 285 AIWDNRATQHYAI+DYG Q RVVRRVT+ GDVPVG+DG+RS Sbjct: 254 AIWDNRATQHYAIDDYGDQPRVVRRVTLGGDVPVGIDGQRS 294 >Rv3406 [Q] COG2175 Probable taurine catabolism dioxygenase Mtu Mycobacterium tuberculosis H37Rv Length = 295 Score = 281 bits (719), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 144/282 (51%), Positives = 184/282 (65%), Gaps = 3/282 (1%) Query: 5 LLNLHPVAGRIGAEIRDVRLSGDLGQETFHAIRQALLKYKVLFFRGQQHLDDVGQEAFAK 64 L+ + + RIGA+I VRL GDL + IR ALL +KV+FFRGQ LDD Q AFA Sbjct: 4 LITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAG 63 Query: 65 LFGELVAHPT-VPVRDGTGYLLELDSVHGGRANSWHTDVTFDLAYPQASILRAVVIPQAG 123 L G + HP + + D + ++S G+AN WHTDVTF YP AS+LRAV +P G Sbjct: 64 LLGTPIGHPAAIALADDAPIITPINS-EFGKANRWHTDVTFAANYPAASVLRAVSLPSYG 122 Query: 124 GDTVWANTAQAYLDLPPALRQLADTLWALHTNDYDYAARFNTDDAGLKRYREVFTSRIYE 183 G T+WANTA AY +LP L+ L + LWALHTN YDY A + +R+VF + Sbjct: 123 GSTLWANTAAAYAELPEPLKCLTENLWALHTNRYDYVTT-KPLTAAQRAFRQVFEKPDFR 181 Query: 184 TEHPVVRVHPETGERTLVLGHFVKKLLGYPTGDSEHLLKLLESYVIRLENTVRWRWTAGD 243 TEHPVVRVHPETGERTL+ G FV+ +G + +S L ++L+ + ENT+RW W GD Sbjct: 182 TEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGD 241 Query: 244 IAIWDNRATQHYAINDYGSQHRVVRRVTIAGDVPVGVDGRRS 285 +AIWDNRATQH AI+DY QHR++ RVT+ GDVPV V G+ S Sbjct: 242 VAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDVYGQAS 283 >MT3514 [Q] COG2175 Probable taurine catabolism dioxygenase MtC Mycobacterium tuberculosis CDC1551 Length = 295 Score = 281 bits (719), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 144/282 (51%), Positives = 184/282 (65%), Gaps = 3/282 (1%) Query: 5 LLNLHPVAGRIGAEIRDVRLSGDLGQETFHAIRQALLKYKVLFFRGQQHLDDVGQEAFAK 64 L+ + + RIGA+I VRL GDL + IR ALL +KV+FFRGQ LDD Q AFA Sbjct: 4 LITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQHQLDDAEQLAFAG 63 Query: 65 LFGELVAHPT-VPVRDGTGYLLELDSVHGGRANSWHTDVTFDLAYPQASILRAVVIPQAG 123 L G + HP + + D + ++S G+AN WHTDVTF YP AS+LRAV +P G Sbjct: 64 LLGTPIGHPAAIALADDAPIITPINS-EFGKANRWHTDVTFAANYPAASVLRAVSLPSYG 122 Query: 124 GDTVWANTAQAYLDLPPALRQLADTLWALHTNDYDYAARFNTDDAGLKRYREVFTSRIYE 183 G T+WANTA AY +LP L+ L + LWALHTN YDY A + +R+VF + Sbjct: 123 GSTLWANTAAAYAELPEPLKCLTENLWALHTNRYDYVTT-KPLTAAQRAFRQVFEKPDFR 181 Query: 184 TEHPVVRVHPETGERTLVLGHFVKKLLGYPTGDSEHLLKLLESYVIRLENTVRWRWTAGD 243 TEHPVVRVHPETGERTL+ G FV+ +G + +S L ++L+ + ENT+RW W GD Sbjct: 182 TEHPVVRVHPETGERTLLAGDFVRSFVGLDSHESRVLFEVLQRRITMPENTIRWNWAPGD 241 Query: 244 IAIWDNRATQHYAINDYGSQHRVVRRVTIAGDVPVGVDGRRS 285 +AIWDNRATQH AI+DY QHR++ RVT+ GDVPV V G+ S Sbjct: 242 VAIWDNRATQHRAIDDYDDQHRLMHRVTLMGDVPVDVYGQAS 283 >mll5998 Non COG Length = 295 Score = 275 bits (702), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 148/280 (52%), Positives = 181/280 (64%), Gaps = 16/280 (5%) Query: 11 VAGRIGAEIRDVRLSGDLGQETFHAIRQALLKYKVLFFRGQQHLDDVGQEAFAKLFGELV 70 RIGAEIR+V+LS DL T AI +L++KV+FFR Q HLDD GQE FA FG+L Sbjct: 19 CTARIGAEIRNVKLSADLPDRTIAAINGLVLEHKVVFFRDQGHLDDAGQERFALRFGKLS 78 Query: 71 AHPTVPVRDGTGYLLELDSVHGGR-ANSWHTDVTFDLAYPQASILRAVVIPQAGGDTVWA 129 +P +GT + ++D+ G A WH D + AYP+ ++LR V IP GGDTVW+ Sbjct: 79 PYP-----EGTTPIYDIDTARGDTGAYVWHIDWSCMDAYPKIAVLRGVTIPLVGGDTVWS 133 Query: 130 NTAQAYLDLPPALRQLADTLWALHTNDYDYAARFNTDDAGLKRYREVFTSRIYETEHPVV 189 NTA AYLDLP L++LA+ LWA+H+ Y L+ E T + ETEHPVV Sbjct: 134 NTAAAYLDLPLPLQRLANELWAVHSFPGSY----------LRSSTEPNTGPMIETEHPVV 183 Query: 190 RVHPETGERTLVLGHFVKKLLGYPTGDSEHLLKLLESYVIRLENTVRWRWTAGDIAIWDN 249 RVHPETGERTLVLG +V + +G D + LL L ES+V ENTVRW+W GDIAIWDN Sbjct: 184 RVHPETGERTLVLGVYVTRFVGISKYDGQRLLDLFESHVTAQENTVRWKWKEGDIAIWDN 243 Query: 250 RATQHYAINDYGSQHRVVRRVTIAGDVPVGVDGRRSVSRN 289 RAT H A D G Q RVVRR TI G+VPV VDGR SV R+ Sbjct: 244 RATMHCATKDCGDQRRVVRRATIEGEVPVSVDGRYSVVRS 283 >PA3935 [Q] COG2175 Probable taurine catabolism dioxygenase Pae Pseudomonas aeruginosa Length = 277 Score = 175 bits (444), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 111/276 (40%), Positives = 148/276 (53%), Gaps = 6/276 (2%) Query: 6 LNLHPVAGRIGAEIRDVRLSGDLGQETFHAIRQALLKYKVLFFRGQQHLDDVGQEAFAKL 65 L + P++ +GA + + L L AI QALL+++VLFFR Q L+ Q FA Sbjct: 3 LTIQPISPALGAIVSGIDLGAPLDDTGQRAIEQALLEHQVLFFRDQS-LEPRSQARFAAR 61 Query: 66 FGELVAHPTVPVRDGTGYLLELDS-VHGGRANS-WHTDVTFDLAYPQASILRAVVIPQAG 123 FG+L HP P ++ LD+ V R N+ WHTDVTF ++L A +P G Sbjct: 62 FGDLHIHPIYPSVPEQPEVIVLDTAVTDVRDNAIWHTDVTFLETPALGAVLAAKQLPPYG 121 Query: 124 GDTVWANTAQAYLDLPPALRQLADTLWALHTNDYDYA-ARFNTDDAGLKRYREVFTSRIY 182 GDT+WA++ AY L LR+L D L A H + RF +A L R E Sbjct: 122 GDTLWASSTAAYEALSAPLRRLLDGLTATHDIGKSFPRERFGVTEADLARLEEARLKNPP 181 Query: 183 ETEHPVVRVHPETGERTLVLGH-FVKKLLGYPTGDSEHLLKLLESYVIRLENTVRWRWTA 241 + HPVVR HP TG + L + F ++ +S+ LLK L ++ R E TVRWRW Sbjct: 182 RS-HPVVRTHPVTGRKGLFVSDGFTTRINELEPAESDALLKFLFAHATRPEFTVRWRWQE 240 Query: 242 GDIAIWDNRATQHYAINDYGSQHRVVRRVTIAGDVP 277 D+A WDNR TQHYA++DY Q RV+ R TI GD P Sbjct: 241 NDVAFWDNRVTQHYAVDDYRPQRRVMHRATILGDKP 276