BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0257.0015.p (170 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_773150.1| dihydrofolate reductase [Bradyrhizobium japonic... 254 3e-66 ref|YP_781101.1| dihydrofolate reductase [Rhodopseudomonas palus... 234 3e-60 ref|YP_485655.1| dihydrofolate reductase [Rhodopseudomonas palus... 229 1e-58 ref|ZP_08630914.1| dihydrofolate reductase [Bradyrhizobiaceae ba... 226 9e-58 ref|YP_570478.1| dihydrofolate reductase [Rhodopseudomonas palus... 226 1e-57 >ref|NP_773150.1| dihydrofolate reductase [Bradyrhizobium japonicum USDA 110] dbj|BAC51775.1| dihydrofolate reductase [Bradyrhizobium japonicum USDA 110] Length = 169 Score = 254 bits (649), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 129/169 (76%), Positives = 141/169 (83%), Gaps = 1/169 (0%) Query: 1 MEIVLVVAVAENGVIGKDNAIPWRLKSDLRRLKAITLGKPVVMGRKTFESLPRPLPRRTN 60 MEIV VVAVAENGVIG NAIPWR KSD+ R KA+T+GKPV+MGRKTFESLPRPLP RTN Sbjct: 1 MEIVFVVAVAENGVIGAGNAIPWRQKSDMARFKALTIGKPVIMGRKTFESLPRPLPGRTN 60 Query: 61 IVVTRDANYRARGAIVTTSFENARAIALGDALRRFATEIAIIGGAEIYAQWMGIADRLEI 120 IV+TRD YRA GA+VTTS +A AIA GDALRR TEIA+IGGAEIY QW G ADRLEI Sbjct: 61 IVITRDPAYRAAGAVVTTSAVDAEAIARGDALRRSVTEIAVIGGAEIYRQWFGRADRLEI 120 Query: 121 TEVHARPDGDTWFDKIDAKAWEEVARVRNPAGPDDSVDFSYVTYRRRGR 169 TEVHARPDGDT F ID WEE AR+R+PAGP+DS D+SYVTYRRR R Sbjct: 121 TEVHARPDGDTHFG-IDKAEWEETARIRHPAGPNDSADYSYVTYRRRPR 168 >ref|YP_781101.1| dihydrofolate reductase [Rhodopseudomonas palustris BisA53] gb|ABJ06121.1| dihydrofolate reductase [Rhodopseudomonas palustris BisA53] Length = 171 Score = 234 bits (597), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 115/167 (68%), Positives = 137/167 (82%) Query: 1 MEIVLVVAVAENGVIGKDNAIPWRLKSDLRRLKAITLGKPVVMGRKTFESLPRPLPRRTN 60 ++ +L+VAVA+NGVIG A+PWRLKSDL+R KA+TLGKPVVMGRKTF S+ RPLP RTN Sbjct: 2 IDTILIVAVADNGVIGHRGAMPWRLKSDLQRFKALTLGKPVVMGRKTFASIGRPLPGRTN 61 Query: 61 IVVTRDANYRARGAIVTTSFENARAIALGDALRRFATEIAIIGGAEIYAQWMGIADRLEI 120 IVV+RD + + GAIVTTSF AR IA GDALRRFATEIA+IGGAEIY Q++G ADR+E+ Sbjct: 62 IVVSRDDSLKLPGAIVTTSFAEARRIAQGDALRRFATEIAVIGGAEIYQQFLGEADRIEL 121 Query: 121 TEVHARPDGDTWFDKIDAKAWEEVARVRNPAGPDDSVDFSYVTYRRR 167 TEVHA P+GDT F +DA W+E AR+R+ A DS DFSYVTYRRR Sbjct: 122 TEVHACPEGDTVFAPLDAAQWQETARIRHAAAEGDSADFSYVTYRRR 168 >ref|YP_485655.1| dihydrofolate reductase [Rhodopseudomonas palustris HaA2] gb|ABD06744.1| dihydrofolate reductase [Rhodopseudomonas palustris HaA2] Length = 179 Score = 229 bits (584), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 107/166 (64%), Positives = 129/166 (77%) Query: 1 MEIVLVVAVAENGVIGKDNAIPWRLKSDLRRLKAITLGKPVVMGRKTFESLPRPLPRRTN 60 + IVL+VAVA+NGVIG+DNAIPWRLKSDL+R K +TL KP++MGRKT++S+ RPLP RTN Sbjct: 10 LSIVLIVAVADNGVIGRDNAIPWRLKSDLQRFKQLTLNKPIIMGRKTYQSIGRPLPGRTN 69 Query: 61 IVVTRDANYRARGAIVTTSFENARAIALGDALRRFATEIAIIGGAEIYAQWMGIADRLEI 120 IVVTRD + A G +V SF+ A +A GDA+RRFATEIA+IGGAEIYA W+ A R+E+ Sbjct: 70 IVVTRDPTFHADGVVVVPSFDAAEQVACGDAMRRFATEIAVIGGAEIYAHWLPRATRIEL 129 Query: 121 TEVHARPDGDTWFDKIDAKAWEEVARVRNPAGPDDSVDFSYVTYRR 166 TEVHA P GD F +D WEE AR + AGP DS D SYVTYRR Sbjct: 130 TEVHASPPGDATFPALDPSQWEETARTHHAAGPQDSADVSYVTYRR 175 >ref|ZP_08630914.1| dihydrofolate reductase [Bradyrhizobiaceae bacterium SG-6C] gb|EGP06446.1| dihydrofolate reductase [Bradyrhizobiaceae bacterium SG-6C] Length = 176 Score = 226 bits (576), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 108/167 (64%), Positives = 133/167 (79%) Query: 1 MEIVLVVAVAENGVIGKDNAIPWRLKSDLRRLKAITLGKPVVMGRKTFESLPRPLPRRTN 60 ++IV VVAVAENGVIG +NA+PW L+SDL+RLKAIT+G+PV+MGRKT+ S+ RPLP RTN Sbjct: 9 LQIVFVVAVAENGVIGLNNAMPWHLRSDLKRLKAITMGRPVIMGRKTYASIGRPLPGRTN 68 Query: 61 IVVTRDANYRARGAIVTTSFENARAIALGDALRRFATEIAIIGGAEIYAQWMGIADRLEI 120 IVVTRD ++A G +V TS + AR +A GDALRRF TEI +IGGAEI+AQW+ ADRLEI Sbjct: 69 IVVTRDKAFQAPGIVVATSLDAARDVAQGDALRRFVTEIMVIGGAEIFAQWLTKADRLEI 128 Query: 121 TEVHARPDGDTWFDKIDAKAWEEVARVRNPAGPDDSVDFSYVTYRRR 167 TEVHA P+GDT+ +D W+E AR R+ D+VDFSYVTY RR Sbjct: 129 TEVHATPEGDTFLKPVDLAEWQETARTRHSRADGDTVDFSYVTYERR 175 >ref|YP_570478.1| dihydrofolate reductase [Rhodopseudomonas palustris BisB5] gb|ABE40577.1| dihydrofolate reductase [Rhodopseudomonas palustris BisB5] Length = 179 Score = 226 bits (575), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 107/166 (64%), Positives = 132/166 (79%) Query: 1 MEIVLVVAVAENGVIGKDNAIPWRLKSDLRRLKAITLGKPVVMGRKTFESLPRPLPRRTN 60 + IV++VAVAENGVIG+ NAIPWRLKSD RR K +TL KPV+MGRKT++S+ RPLP RTN Sbjct: 10 VSIVIIVAVAENGVIGEGNAIPWRLKSDQRRFKQLTLNKPVIMGRKTYQSIGRPLPGRTN 69 Query: 61 IVVTRDANYRARGAIVTTSFENARAIALGDALRRFATEIAIIGGAEIYAQWMGIADRLEI 120 IVVTRD +++A G +V SFE A +A GDA+RR ATE+ ++GG+EIYA W+ A +E+ Sbjct: 70 IVVTRDTHFQAAGVVVAPSFEAAERVAAGDAMRRSATEVVVVGGSEIYAHWLPRATCIEL 129 Query: 121 TEVHARPDGDTWFDKIDAKAWEEVARVRNPAGPDDSVDFSYVTYRR 166 TEVHA P GDT F ID WEEVAR R+ AGP+DSV+FSYVTYRR Sbjct: 130 TEVHASPQGDTTFPAIDPDQWEEVARTRHGAGPEDSVEFSYVTYRR 175