BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0255.0022.p (205 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002287268.1| GTP cyclohydrolase I [Oligotropha carboxidov... 349 2e-94 ref|ZP_07026271.1| GTP cyclohydrolase I [Afipia sp. 1NLS2] >gi|2... 342 2e-92 ref|YP_003756837.1| GTP cyclohydrolase I [Hyphomicrobium denitri... 322 3e-86 ref|YP_004674452.1| GTP cyclohydrolase 1 [Hyphomicrobium sp. MC1... 317 5e-85 ref|YP_779732.1| GTP cyclohydrolase I [Rhodopseudomonas palustri... 300 6e-80 >ref|YP_002287268.1| GTP cyclohydrolase I [Oligotropha carboxidovorans OM5] ref|YP_004631233.1| GTP cyclohydrolase I [Oligotropha carboxidovorans OM5] gb|ACI91403.1| GTP cyclohydrolase I [Oligotropha carboxidovorans OM5] gb|AEI01417.1| GTP cyclohydrolase I [Oligotropha carboxidovorans OM4] gb|AEI04992.1| GTP cyclohydrolase I [Oligotropha carboxidovorans OM5] Length = 210 Score = 349 bits (895), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 160/199 (80%), Positives = 178/199 (89%) Query: 5 VHTLDRARAAQTESDKPTRAEVEAAVRTIIRWTGDDPERDGLLETPARVTRSFEEFFAGY 64 V L+R R A+ ES +P RAEVEAAVRTIIRW GDDP+RDGL+ETP+RV R+FEEFF GY Sbjct: 7 VQVLERDRKAEEESARPDRAEVEAAVRTIIRWAGDDPKRDGLIETPSRVARAFEEFFIGY 66 Query: 65 DQRPAEILEKTFEEIEGYDEMIALRGIRFESHCEHHMAPIIGQAWVAYIPNGRVVGISKL 124 Q P IL+KTFEEI+GYDEMI LR +RFESHCEHHMAPI+G+AWVAYIPNGRVVGISKL Sbjct: 67 SQNPTTILQKTFEEIDGYDEMITLRAVRFESHCEHHMAPIVGKAWVAYIPNGRVVGISKL 126 Query: 125 ARVVDIYARRLQIQEKMTAQIANTINEVLKPQGVGVIIKASHHCMTTRGVHKPDTDLVTS 184 ARVV++YA+RLQIQEKMTAQIANTINEVLKPQGV V+IKA HHCMTTRG+HKP TDLVTS Sbjct: 127 ARVVEVYAKRLQIQEKMTAQIANTINEVLKPQGVAVLIKAQHHCMTTRGIHKPGTDLVTS 186 Query: 185 RMLGCFRDNALTRQEFLGI 203 RMLGCFRDNA TRQEFL + Sbjct: 187 RMLGCFRDNATTRQEFLSM 205 >ref|ZP_07026271.1| GTP cyclohydrolase I [Afipia sp. 1NLS2] gb|EFI53413.1| GTP cyclohydrolase I [Afipia sp. 1NLS2] Length = 208 Score = 342 bits (876), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 157/199 (78%), Positives = 176/199 (88%) Query: 5 VHTLDRARAAQTESDKPTRAEVEAAVRTIIRWTGDDPERDGLLETPARVTRSFEEFFAGY 64 V L+R R+ S++P RAEVE A RTIIRWTGDDP+RDGL+ETP+RV R+FEEFF GY Sbjct: 5 VKVLERERSMTDVSERPDRAEVEDAFRTIIRWTGDDPKRDGLIETPSRVARAFEEFFIGY 64 Query: 65 DQRPAEILEKTFEEIEGYDEMIALRGIRFESHCEHHMAPIIGQAWVAYIPNGRVVGISKL 124 Q P +L+KTFEEIEGYDEMI LRG+RFESHCEHHMAPI+G+AWVAYIPNGRVVGISKL Sbjct: 65 SQNPVTVLQKTFEEIEGYDEMITLRGVRFESHCEHHMAPIVGKAWVAYIPNGRVVGISKL 124 Query: 125 ARVVDIYARRLQIQEKMTAQIANTINEVLKPQGVGVIIKASHHCMTTRGVHKPDTDLVTS 184 ARVV+IYA+RLQIQEKMTAQIANTIN+VLKPQGV V+IKA HHCMTTRG+HKP TDLVTS Sbjct: 125 ARVVEIYAKRLQIQEKMTAQIANTINDVLKPQGVAVLIKAQHHCMTTRGIHKPGTDLVTS 184 Query: 185 RMLGCFRDNALTRQEFLGI 203 RMLGCFRDN TRQEFL + Sbjct: 185 RMLGCFRDNPATRQEFLSM 203 >ref|YP_003756837.1| GTP cyclohydrolase I [Hyphomicrobium denitrificans ATCC 51888] gb|ADJ24516.1| GTP cyclohydrolase I [Hyphomicrobium denitrificans ATCC 51888] Length = 197 Score = 322 bits (824), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 148/188 (78%), Positives = 165/188 (87%) Query: 16 TESDKPTRAEVEAAVRTIIRWTGDDPERDGLLETPARVTRSFEEFFAGYDQRPAEILEKT 75 + KPTRAEVEAAVRTI+RW+GDDP RDGLLETPARV R++EE+F GY+ P IL+KT Sbjct: 2 SSEKKPTRAEVEAAVRTILRWSGDDPSRDGLLETPARVVRAYEEYFRGYNDDPKAILQKT 61 Query: 76 FEEIEGYDEMIALRGIRFESHCEHHMAPIIGQAWVAYIPNGRVVGISKLARVVDIYARRL 135 FEEIEGYDEMI LRGIRFESHCEHHMAPIIG+AWVAYIP GRVVGISKLAR VD +A+RL Sbjct: 62 FEEIEGYDEMIVLRGIRFESHCEHHMAPIIGRAWVAYIPRGRVVGISKLARAVDAFAKRL 121 Query: 136 QIQEKMTAQIANTINEVLKPQGVGVIIKASHHCMTTRGVHKPDTDLVTSRMLGCFRDNAL 195 QIQEKMTAQIANTI EVL P+GV V++KA HHCMTTRG HKP TD+VTSRMLG FRDN + Sbjct: 122 QIQEKMTAQIANTIQEVLDPEGVAVVLKAEHHCMTTRGAHKPGTDMVTSRMLGVFRDNPI 181 Query: 196 TRQEFLGI 203 TRQEFL + Sbjct: 182 TRQEFLAL 189 >ref|YP_004674452.1| GTP cyclohydrolase 1 [Hyphomicrobium sp. MC1] emb|CCB63876.1| GTP cyclohydrolase 1 [Hyphomicrobium sp. MC1] Length = 226 Score = 317 bits (813), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 147/184 (79%), Positives = 164/184 (89%) Query: 20 KPTRAEVEAAVRTIIRWTGDDPERDGLLETPARVTRSFEEFFAGYDQRPAEILEKTFEEI 79 KPTRA+VE+A++TI+RWTG+DP+RDGL ETPARVT++FEE+F GY + P IL KTFEEI Sbjct: 35 KPTRADVESAIKTILRWTGEDPDRDGLKETPARVTKAFEEWFRGYGEDPEAILNKTFEEI 94 Query: 80 EGYDEMIALRGIRFESHCEHHMAPIIGQAWVAYIPNGRVVGISKLARVVDIYARRLQIQE 139 EGYDEMI LRGIRFESHCEHHMAPIIG+AWV YIPNGRVVGISKLARVV+ YA+RLQIQE Sbjct: 95 EGYDEMIVLRGIRFESHCEHHMAPIIGRAWVGYIPNGRVVGISKLARVVNAYAKRLQIQE 154 Query: 140 KMTAQIANTINEVLKPQGVGVIIKASHHCMTTRGVHKPDTDLVTSRMLGCFRDNALTRQE 199 KMTAQIAN I E L PQGV VIIKA HHCMTTRGV KP TD+VTSRMLG FRDNA+TRQE Sbjct: 155 KMTAQIANAIEEALHPQGVAVIIKAEHHCMTTRGVLKPGTDMVTSRMLGVFRDNAITRQE 214 Query: 200 FLGI 203 FL + Sbjct: 215 FLAL 218 >ref|YP_779732.1| GTP cyclohydrolase I [Rhodopseudomonas palustris BisA53] gb|ABJ04752.1| GTP cyclohydrolase [Rhodopseudomonas palustris BisA53] Length = 200 Score = 300 bits (769), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 138/194 (71%), Positives = 162/194 (83%) Query: 11 ARAAQTESDKPTRAEVEAAVRTIIRWTGDDPERDGLLETPARVTRSFEEFFAGYDQRPAE 70 AR A KP+ EVEAA RT+IRW GDDP+R GL ETPAR R+F E+FAGY+Q P Sbjct: 5 ARIAAPSQTKPSPEEVEAAFRTLIRWAGDDPDRAGLKETPARAARAFREYFAGYEQDPLA 64 Query: 71 ILEKTFEEIEGYDEMIALRGIRFESHCEHHMAPIIGQAWVAYIPNGRVVGISKLARVVDI 130 IL KTF+E GY+EM+ LRGI FESHCEHH+APIIGQAWVAY+P+GRVVG+SKLARVVD Sbjct: 65 ILNKTFDETGGYEEMVVLRGIPFESHCEHHLAPIIGQAWVAYVPSGRVVGLSKLARVVDA 124 Query: 131 YARRLQIQEKMTAQIANTINEVLKPQGVGVIIKASHHCMTTRGVHKPDTDLVTSRMLGCF 190 YA+RLQIQE+MT++IA + +VLKPQGVGV+IKA+HHCM++RGVHK D+VTS MLGCF Sbjct: 125 YAKRLQIQERMTSEIAFAVQDVLKPQGVGVVIKATHHCMSSRGVHKVGADMVTSCMLGCF 184 Query: 191 RDNALTRQEFLGIA 204 RDNALTRQEFL IA Sbjct: 185 RDNALTRQEFLAIA 198