BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0251.0026.p (203 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_577934.1| TetR family transcriptional regulator [Nitrobac... 137 9e-31 ref|YP_004494298.1| hypothetical protein AS9A_3053 [Amycolicicoc... 69 5e-10 ref|YP_003514457.1| TetR family transcriptional regulator [Stack... 62 5e-08 ref|YP_004811325.1| TetR family transcriptional regulator [Strep... 62 5e-08 ref|YP_546670.1| TetR family transcriptional regulator [Methylob... 62 6e-08 >ref|YP_577934.1| TetR family transcriptional regulator [Nitrobacter hamburgensis X14] gb|ABE63474.1| transcriptional regulator, TetR family [Nitrobacter hamburgensis X14] Length = 204 Score = 137 bits (345), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 68/189 (35%), Positives = 112/189 (59%), Gaps = 2/189 (1%) Query: 16 GQLQQ-KHIAGVVYDLIAEQGIENLTMRQVADAAKVSLGTITYHFRSKEALIAAALESGY 74 G++Q+ K++ V+ +I+E GI+ +MRQ+AD A VS GTI YHF +K L+ AAL++ Sbjct: 14 GRVQRRKNLLDAVHAVISESGIDGASMRQIADRANVSTGTINYHFGNKHKLMMAALQASC 73 Query: 75 ELPDDWDQYKGSPAAQLRRIALSYALQSPKERWWRFWINYVAMSTRDAEIQAIQTRRFDK 134 P + D SP AQLR + S+A +S +R+W FW+NY A TRD E++ Q +RF++ Sbjct: 74 LPPRECDSSADSPLAQLRVLVFSHAFRSSTDRFWHFWVNYTAAGTRDTEMRKHQNQRFER 133 Query: 135 QRRFWIKLFREGKELGEIRGDLPVEETVDRMLVEVHGHVILQLVKPNPRMRMDAREAINR 194 Q+ W KL GE+ E +++L+ +HG + Q+++P R+ + + R Sbjct: 134 QQAAWTKLIESAINAGELPSCPDAEVVSEQLLIFIHGLAMRQIMQPGAESRLHCEKLLER 193 Query: 195 MIDAILDKP 203 + L++P Sbjct: 194 YFE-TLERP 201 >ref|YP_004494298.1| hypothetical protein AS9A_3053 [Amycolicicoccus subflavus DQS3-9A1] gb|AEF41498.1| hypothetical protein AS9A_3053 [Amycolicicoccus subflavus DQS3-9A1] Length = 198 Score = 68.6 bits (166), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 54/191 (28%), Positives = 94/191 (49%), Gaps = 7/191 (3%) Query: 16 GQLQQK-HIAGVVYDLIAEQGIENLTMRQVADAAKVSLGTITYHFRSKEALIAAALESGY 74 GQ+ ++ +AG+V + AEQG++++++R+VA AA +S+G + +HFR+K+A++ AA Sbjct: 6 GQIDRRAQLAGIVVRIAAEQGLDHVSVREVAAAAGLSIGAVQHHFRTKDAMLLAAFRHYA 65 Query: 75 ELPDDWDQY---KGSPAAQLRRIALSYA-LQSPKERWWRFWINYVAMSTRDAEIQAIQTR 130 + D + GSP +RR+ L + R +I + A S E+ + Sbjct: 66 DALTDRIRSMDRSGSPHDTIRRLLFQLLPLDDARSTETRMFIAFAARSIVTPELARVYHE 125 Query: 131 RFDKQRRFWIKLFREGKELGEIRGDLPVEETVDRMLVEVHGHVILQLVKP-NPRMRMDAR 189 D+ R +L + ++ G LP ET+ R L+ V LQ V + R A Sbjct: 126 GLDQLRAVLTRLVQVAQDSGMAVTHLPA-ETLARTLLAVADGATLQTVTDRSEEAREHAI 184 Query: 190 EAINRMIDAIL 200 IN +D + Sbjct: 185 AEINTALDLVF 195 >ref|YP_003514457.1| TetR family transcriptional regulator [Stackebrandtia nassauensis DSM 44728] gb|ADD45364.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis DSM 44728] Length = 199 Score = 62.0 bits (149), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 93/187 (49%), Gaps = 12/187 (6%) Query: 22 HIAGVVYDLIAEQGIENLTMRQVADAAKVSLGTITYHFRSKEALIAAALESGYELPDDWD 81 IA +DLI+E+G+E T+R VA A+VSLG + F +K+ +I LE + + Sbjct: 13 QIAKAAFDLISERGLEAATLRDVALRAEVSLGAVQRCFSTKDEMIVFVLEYMNQRVTERI 72 Query: 82 QYKGS----PAAQLRRIALSYALQSPKERW----WRFWINYVAMSTRDAEIQAIQTRRFD 133 Q + S P + + + + P +R R W+ ++A + + ++ AIQ ++ Sbjct: 73 QGRISATADPDSTVTMLEQTLIGIIPVDRLSLAESRVWLAFIAQAAVNPKLAAIQREQYT 132 Query: 134 KQRRFWIKLFREGKELGEIRGDLPVEETVDRMLVEVHGHVILQLV-KPNPRMRMDAREAI 192 + L + G++ G++R DL + + +L G I LV + +P DA A+ Sbjct: 133 GTAELFALLLKVGQDTGKLRADLEPADEAESLLTFTDGLNIQILVGRLSPD---DALAAL 189 Query: 193 NRMIDAI 199 +R +DA+ Sbjct: 190 HRRLDAL 196 >ref|YP_004811325.1| TetR family transcriptional regulator [Streptomyces violaceusniger Tu 4113] gb|AEM81045.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113] Length = 212 Score = 62.0 bits (149), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 53/204 (25%), Positives = 93/204 (45%), Gaps = 9/204 (4%) Query: 2 SVNSFKRTPPPETRGQLQQKHIAGVVYDLIAEQGIENLTMRQVADAAKVSLGTITYHFRS 61 +V + +RT P +++++ I LIAE+G + + +R+VA AA+VS+GT+TYHF S Sbjct: 13 AVEASRRTRQPT---EVRRRLIVEAAVPLIAERGTKGVGVREVAAAAEVSVGTVTYHFES 69 Query: 62 KEALIAAAL----ESGYELPDDWDQYKGSPAAQLRRIALSYALQSPKERWWRFWINYVAM 117 + +++ A+ E Y + S A L R+ + ++ WR W +Y Sbjct: 70 VQEVLSEAMVLHIERYYAALSEAAATATSGAEGL-RLLIDALFTDDTDQHWRMWFDYWNA 128 Query: 118 STRDAEIQAIQTRRFDKQRRFWIKLFREGKELGEIRGDLPVEETVDRMLVEVHGHVILQL 177 RD Q R++ L G++ G+ D P + + R G + +L Sbjct: 129 GERDESFARGQAERYEAWHGEIQSLVERGRDEGDFVCDDPADFAL-RFSALADGLALRRL 187 Query: 178 VKPNPRMRMDAREAINRMIDAILD 201 + DAR + R + A L+ Sbjct: 188 RQAPALTVADARRHLRRFVAAELE 211 >ref|YP_546670.1| TetR family transcriptional regulator [Methylobacillus flagellatus KT] gb|ABE50829.1| transcriptional regulator, TetR family [Methylobacillus flagellatus KT] Length = 214 Score = 61.6 bits (148), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 45/169 (26%), Positives = 86/169 (50%), Gaps = 6/169 (3%) Query: 15 RGQLQQKHIAGVVYDLIAEQGIENLTMRQVADAAKVSLGTITYHFRSKEALIAAALESGY 74 RG+ Q +I V DL A+ + ++T +Q+A A+KV+ + Y+F++K+ L A++ Sbjct: 13 RGETQAANILSVALDLFAKHHVASVTTKQIAAASKVNSALLYYYFKNKDDLFRQAVDHAI 72 Query: 75 E---LPDDWDQYKGSPAAQLRRIALSYALQSPK--ERWWRFWINYVAMSTRDAEIQAIQT 129 L + Q A++ L+ LQ + ++ + ++Y + +R AE A + Sbjct: 73 GQVLLRFEHVQKTAHGPAEILSAWLNLHLQQVELIRKFVKVAVDYASSESRTAETDATIS 132 Query: 130 RRFDKQRRFWIKLFREGKELGEIRGDLPVEETVDRMLVEVHGHVILQLV 178 R +D +RR ++ +EG E G+ + VE+T + + G VI +V Sbjct: 133 RFYDTERRMLCQVLQEGIETGDF-AQVDVEQTATFISTFLDGIVIRSIV 180