BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0248.0045.p (163 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_577876.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridi... 281 3e-74 ref|ZP_08629242.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteri... 279 9e-74 ref|YP_318841.1| 7,8-dihydro-6-hydroxymethylpterin-pyrophosphoki... 268 3e-70 ref|ZP_01046543.1| 7,8-Dihydro-6-hydroxymethylpterin-pyrophospho... 266 5e-70 ref|NP_947183.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridi... 263 7e-69 >ref|YP_577876.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Nitrobacter hamburgensis X14] gb|ABE63416.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Nitrobacter hamburgensis X14] Length = 163 Score = 281 bits (719), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 136/163 (83%), Positives = 145/163 (88%) Query: 1 MADVLIALGGNVGDVRATFRKAIANICGMTQAALIARSSDYSTPPWGEQQQDSFINACIE 60 MA VLIALGGNVGDVR TFRKAIANICGMTQAAL+ARSSDY+TPPWGE+ QD F+NACIE Sbjct: 1 MASVLIALGGNVGDVRQTFRKAIANICGMTQAALVARSSDYATPPWGEENQDRFVNACIE 60 Query: 61 IETSLDPHALLFTLHKIEAKFGRDRAHEQRWGPRTLDLDLIAYDDVTLNKPELTLPHPRL 120 I+T LDPHALLFTLHKIE KFGRDR+ E RWGPRTLDLDLIAYDD L+KPELTLPHPRL Sbjct: 61 IDTRLDPHALLFTLHKIEKKFGRDRSKETRWGPRTLDLDLIAYDDAVLDKPELTLPHPRL 120 Query: 121 FERAFVLVPLAEIVPDRVIAGRRVADALAEVSADGIFRLADLD 163 FERAFVLVPLAEI PDR+IAGR A ALA VS GI RL+DLD Sbjct: 121 FERAFVLVPLAEIAPDRIIAGRTPAAALAGVSTAGIERLSDLD 163 >ref|ZP_08629242.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Bradyrhizobiaceae bacterium SG-6C] gb|EGP07735.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Bradyrhizobiaceae bacterium SG-6C] Length = 177 Score = 279 bits (714), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 136/162 (83%), Positives = 147/162 (90%) Query: 1 MADVLIALGGNVGDVRATFRKAIANICGMTQAALIARSSDYSTPPWGEQQQDSFINACIE 60 MA VLIALGGNVGDVRATF KAIANICGMTQAAL ARSSDY TPPWG++QQ+ FINACIE Sbjct: 15 MASVLIALGGNVGDVRATFTKAIANICGMTQAALAARSSDYMTPPWGDEQQEPFINACIE 74 Query: 61 IETSLDPHALLFTLHKIEAKFGRDRAHEQRWGPRTLDLDLIAYDDVTLNKPELTLPHPRL 120 I+TSLDPHALLFTLHKIE KFGRDRA+E+RWGPRTLDLD+IAYDDV L+KPELTLPHPRL Sbjct: 75 IDTSLDPHALLFTLHKIEKKFGRDRANERRWGPRTLDLDIIAYDDVRLDKPELTLPHPRL 134 Query: 121 FERAFVLVPLAEIVPDRVIAGRRVADALAEVSADGIFRLADL 162 FERAFVLVPLAEI PDR+IAG+ ALA +SADGI RL DL Sbjct: 135 FERAFVLVPLAEIAPDRLIAGQTPRQALASLSADGIERLPDL 176 >ref|YP_318841.1| 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Nitrobacter winogradskyi Nb-255] gb|ABA05489.1| 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK [Nitrobacter winogradskyi Nb-255] Length = 163 Score = 268 bits (684), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 131/162 (80%), Positives = 142/162 (87%) Query: 1 MADVLIALGGNVGDVRATFRKAIANICGMTQAALIARSSDYSTPPWGEQQQDSFINACIE 60 MA VLIALGGNVGDVR TFRKAIANI GM QAAL+ARSSDY+TPPWGE++Q F+NACIE Sbjct: 1 MASVLIALGGNVGDVRQTFRKAIANIRGMAQAALLARSSDYATPPWGEEKQARFVNACIE 60 Query: 61 IETSLDPHALLFTLHKIEAKFGRDRAHEQRWGPRTLDLDLIAYDDVTLNKPELTLPHPRL 120 I+T LDPHALLFTL KIE KFGRDRA EQRWGPRTLDLDLIAYDD L+KPELTLPHPRL Sbjct: 61 IDTGLDPHALLFTLQKIEKKFGRDRAAEQRWGPRTLDLDLIAYDDAILDKPELTLPHPRL 120 Query: 121 FERAFVLVPLAEIVPDRVIAGRRVADALAEVSADGIFRLADL 162 FERAFVLVPLAEI PDR+IAG+ A ALA++S GI RL DL Sbjct: 121 FERAFVLVPLAEIAPDRIIAGQTPARALADISTAGIERLPDL 162 >ref|ZP_01046543.1| 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK [Nitrobacter sp. Nb-311A] gb|EAQ35379.1| 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK [Nitrobacter sp. Nb-311A] Length = 163 Score = 266 bits (681), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 129/162 (79%), Positives = 140/162 (86%) Query: 1 MADVLIALGGNVGDVRATFRKAIANICGMTQAALIARSSDYSTPPWGEQQQDSFINACIE 60 MA VLI+LGGNVGDVR TFRKAIANICGM QA L+ARSSDY+TPPWGE+ Q F+NACIE Sbjct: 1 MASVLISLGGNVGDVRQTFRKAIANICGMAQAVLVARSSDYATPPWGEENQARFVNACIE 60 Query: 61 IETSLDPHALLFTLHKIEAKFGRDRAHEQRWGPRTLDLDLIAYDDVTLNKPELTLPHPRL 120 I+T LDPHALLFTLHKIE KFGRDR+ E+RW PRTLDLDLIAYDD L+KPELTLPHPR Sbjct: 61 IDTGLDPHALLFTLHKIEKKFGRDRSAEKRWRPRTLDLDLIAYDDAILDKPELTLPHPRT 120 Query: 121 FERAFVLVPLAEIVPDRVIAGRRVADALAEVSADGIFRLADL 162 FERAFVLVPLAEI PDRVIAGR A ALA++S GI RL DL Sbjct: 121 FERAFVLVPLAEIAPDRVIAGRTPAHALADISTAGIERLPDL 162 >ref|NP_947183.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Rhodopseudomonas palustris CGA009] ref|YP_001991040.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Rhodopseudomonas palustris TIE-1] emb|CAE27279.1| putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Rhodopseudomonas palustris CGA009] gb|ACF00565.1| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Rhodopseudomonas palustris TIE-1] Length = 163 Score = 263 bits (672), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 126/163 (77%), Positives = 142/163 (87%) Query: 1 MADVLIALGGNVGDVRATFRKAIANICGMTQAALIARSSDYSTPPWGEQQQDSFINACIE 60 M LIALGGNVGDVRATF KAIANICGMTQA LIARS DY+TPPWG++QQD F+NAC+ Sbjct: 1 MPRALIALGGNVGDVRATFDKAIANICGMTQAELIARSPDYATPPWGDEQQDRFVNACVA 60 Query: 61 IETSLDPHALLFTLHKIEAKFGRDRAHEQRWGPRTLDLDLIAYDDVTLNKPELTLPHPRL 120 IET+LDPHALLFTLHKIE +FGRDRA+E+RWGPRTLDLDLIAYDD +N+P+LTLPHPRL Sbjct: 61 IETALDPHALLFTLHKIEKRFGRDRANERRWGPRTLDLDLIAYDDAVINRPDLTLPHPRL 120 Query: 121 FERAFVLVPLAEIVPDRVIAGRRVADALAEVSADGIFRLADLD 163 FERAFVLVPL ++VPD VIAGR + DALA +S GI RL D D Sbjct: 121 FERAFVLVPLLDVVPDPVIAGRSLKDALAGLSTAGIERLPDRD 163