BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0246.0002.p (1011 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08629997.1| cobalt-zinc-cadmium resistance protein CzcA [... 977 0.0 ref|ZP_01048443.1| metal ion efflux RND protein family protein [... 945 0.0 ref|YP_003066996.1| cation efflux system protein czcA [Methyloba... 940 0.0 ref|YP_002963702.1| Cobalt-zinc-cadmium resistance protein czcA ... 939 0.0 ref|YP_001926736.1| heavy metal efflux pump, CzcA family [Methyl... 936 0.0 >ref|ZP_08629997.1| cobalt-zinc-cadmium resistance protein CzcA [Bradyrhizobiaceae bacterium SG-6C] gb|EGP07366.1| cobalt-zinc-cadmium resistance protein CzcA [Bradyrhizobiaceae bacterium SG-6C] Length = 1074 Score = 977 bits (2526), Expect = 0.0, Method: Compositional matrix adjust. Identities = 502/747 (67%), Positives = 598/747 (80%), Gaps = 36/747 (4%) Query: 1 MIERIIGLAIQRRWMVVTLAAILMFLGGLALTRLPIDAVPDITNKQVQINTVAPALSPAE 60 MI RI+ L+I+ RW+V+ L+ ++ G +L RLP+DAVPDITNKQVQINTVAPALSP E Sbjct: 1 MISRILDLSIRHRWLVLLLSLGVVAAGAWSLARLPVDAVPDITNKQVQINTVAPALSPVE 60 Query: 61 IEKQITFPIETALXGRRG---SRARAR---SPATA--------------------SRRSR 94 IEKQ+TF IETAL G G +R+ +R S TA R+ Sbjct: 61 IEKQVTFRIETALAGIAGLQTTRSLSRNGFSQVTAIFSENIDIYFARQQIGERLTDVRAS 120 Query: 95 RCSAXEPRIGPTSTGLGEIYMWTV----HYSGQKVQADGAPGLQSDGRFLTADGQMLQSE 150 EPR+GP STGLGEIYMWTV H+SG G G Q+DG F TA+G++L+++ Sbjct: 121 LPPGTEPRLGPISTGLGEIYMWTVSLDPHFSG------GRSGWQTDGSFRTAEGEVLRND 174 Query: 151 VEKDAYLRTVQDWIIKPQIKMVPGVAGVDTIGGYLKQYQVHPDAAKLIALGLTFADVAKA 210 +E+ AYLRTVQDWII+PQIK VPGVAGVD+IGGY+KQYQV PD AKLI+LGL+F+DV +A Sbjct: 175 IERGAYLRTVQDWIIRPQIKTVPGVAGVDSIGGYIKQYQVKPDPAKLISLGLSFSDVVRA 234 Query: 211 IETNNVSRGARYIERNGEGFVVRSGGRLENIDELGAVVVTTRGGVPVRIRDLATLSIGGE 270 IE NN+SRGA I+RNGEG VR+GGRLE + ++G V V TRG VP+R+RD+A +SIGGE Sbjct: 235 IEANNISRGASTIDRNGEGIAVRTGGRLEKLADIGDVTVITRGAVPIRVRDVAEVSIGGE 294 Query: 271 TRTGSASENGREVVVGTALMLIGANSRTVSAAVDAKLRTIMPSLPAGIEVKTVLDRTQLV 330 R+GSAS +GREVVVGTALMLIG+NSRTVSAAVDA++ I +LP G+ ++T L+RTQLV Sbjct: 295 IRSGSASRDGREVVVGTALMLIGSNSRTVSAAVDARMADIRRTLPPGVTIETALNRTQLV 354 Query: 331 DATIGTVARNLSEGALLVIAVLFVLLGNFRAALITALVIPVAMLMTAIGMWQGRISANLM 390 DAT+ TVA+NL+EGALLVIAVLF+LLGN RAA I ALVIP+AMLMTA GM QGRISANLM Sbjct: 355 DATVNTVAKNLAEGALLVIAVLFLLLGNVRAAFIAALVIPLAMLMTAAGMLQGRISANLM 414 Query: 391 SLGALDFGLIVDGAVIITENSLRHLAEKQQALGRVLTRDERLATVRASAVEMVQPSLYGQ 450 SLGALDFGLIVDGAVIITEN+LRHLAEKQ +GR L+ ERLATV+ SA EM+ PS+YGQ Sbjct: 415 SLGALDFGLIVDGAVIITENALRHLAEKQTEVGRPLSLQERLATVKQSAEEMIGPSVYGQ 474 Query: 451 AIILLVYVPLLTFTGVEGKMFEPMALTVILALAAAFVLSLTLVPALIAIGITGRVQEQEN 510 AII+LVYVPLLTF+GVEGKMFEPMALTVILAL +AFVLSLT VPA+IAI ITGRV E +N Sbjct: 475 AIIILVYVPLLTFSGVEGKMFEPMALTVILALVSAFVLSLTFVPAMIAIAITGRVTETDN 534 Query: 511 RLVAALKRCYSPLLRRAVATPMPVIAVAVVLFAAALFGFFRLGQEFIPSLDEKNIAMHAL 570 R V +LK Y PLL+R +A P IA +VLFA AL FFRLGQEFIP+LDEKNIAMHAL Sbjct: 535 RAVRSLKTWYVPLLKRTIARPAVAIATGIVLFAGALLLFFRLGQEFIPTLDEKNIAMHAL 594 Query: 571 RIPSTALSQSQAMQLSVEKAVSRFPQVSFVFSKTGTAEVASDPMPPNASDTFIILKPREQ 630 RIPST+L+QSQAMQL++EKA+ FPQV+ V+SKTGTAEVASDPMPP+ASDTFIILKP++Q Sbjct: 595 RIPSTSLNQSQAMQLNIEKAIIAFPQVAHVYSKTGTAEVASDPMPPSASDTFIILKPQDQ 654 Query: 631 WPDPSLTNEQLIEDLSKAVGRLPGNVYEFTQPIQMRFNELLAGVRGDIAVKVFGDEFGPM 690 WPDP LT L++ ++ V LPGN YEFTQPIQMRFNELLAGVRGD+AVKVFGDEF P+ Sbjct: 655 WPDPKLTKAALLDQIADTVRELPGNAYEFTQPIQMRFNELLAGVRGDLAVKVFGDEFEPL 714 Query: 691 QKAANQIAAALRGVRGATDVKVEQAGG 717 ++A QI+A LR +GATDV++EQA G Sbjct: 715 LRSAGQISAILRKTKGATDVRIEQASG 741 >ref|ZP_01048443.1| metal ion efflux RND protein family protein [Nitrobacter sp. Nb-311A] gb|EAQ33602.1| metal ion efflux RND protein family protein [Nitrobacter sp. Nb-311A] Length = 1067 Score = 945 bits (2442), Expect = 0.0, Method: Compositional matrix adjust. Identities = 500/746 (67%), Positives = 583/746 (78%), Gaps = 29/746 (3%) Query: 1 MIERIIGLAIQRRWMVVTLAAILMFLGGLALTRLPIDAVPDITNKQVQINTVAPALSPAE 60 MI R++ ++ +RW+VV L G +L++LPIDAVPDITN QVQINT AP+LSP + Sbjct: 1 MINRVLRFSVHQRWLVVLLTFAAAAFGLWSLSKLPIDAVPDITNNQVQINTAAPSLSPFD 60 Query: 61 IEKQITFPIETALXGRRG---SRARAR---SPATASRRSR------------RCSA---- 98 +EKQ+T+P+ETAL G G +R+ +R S TA R R + Sbjct: 61 VEKQVTYPVETALAGIPGLEYTRSLSRNGFSQVTAVFNERIDIYFARQQVNERLNVVKAD 120 Query: 99 ----XEPRIGPTSTGLGEIYMWTVHY--SGQKVQA-DGAPGLQSDGRFLTADGQMLQSEV 151 E +GP STGLGEIYMWTVHY +G+ V DG G QSDG +LT +GQ L +E+ Sbjct: 121 LPLGTETHMGPISTGLGEIYMWTVHYKPAGEVVPVRDGQAGWQSDGSYLTPEGQRLSTEM 180 Query: 152 EKDAYLRTVQDWIIKPQIKMVPGVAGVDTIGGYLKQYQVHPDAAKLIALGLTFADVAKAI 211 E+ AYLRTVQDWII+PQ+K VPGVAGVD IGG+ KQY V PD AKLI LG++FA++ +A+ Sbjct: 181 ERAAYLRTVQDWIIRPQLKTVPGVAGVDVIGGFAKQYHVQPDPAKLIGLGISFAELGEAL 240 Query: 212 ETNNVSRGARYIERNGEGFVVRSGGRLENIDELGAVVVTTRGGVPVRIRDLATLSIGGET 271 E NN++RGA YIERNGE +VVRS GRLEN++E+G VVVTTRGGVPVR+ D+A + IG E Sbjct: 241 ERNNMNRGAGYIERNGERYVVRSAGRLENMEEIGNVVVTTRGGVPVRVNDVAKVKIGREL 300 Query: 272 RTGSASENGREVVVGTALMLIGANSRTVSAAVDAKLRTIMPSLPAGIEVKTVLDRTQLVD 331 RTGSASENG+EVVVGTALMLIG NSRTVSAAVDAK++ I SLP +E KTVL+RT LVD Sbjct: 301 RTGSASENGQEVVVGTALMLIGGNSRTVSAAVDAKMQVINKSLPPSVEAKTVLNRTLLVD 360 Query: 332 ATIGTVARNLSEGALLVIAVLFVLLGNFRAALITALVIPVAMLMTAIGMWQGRISANLMS 391 AT+ TV+ NL EGA LVI VLF+LLGN RAA+ITALVIP+ ML+T GM QG+ISANLMS Sbjct: 361 ATVKTVSMNLIEGAALVILVLFLLLGNIRAAIITALVIPITMLLTMTGMVQGKISANLMS 420 Query: 392 LGALDFGLIVDGAVIITENSLRHLAEKQQALGRVLTRDERLATVRASAVEMVQPSLYGQA 451 LGALDFGLIVDGAVII ENSLRHLAEKQ LGR L+ +ERL TVR SA EM++PS+YGQA Sbjct: 421 LGALDFGLIVDGAVIIAENSLRHLAEKQHELGRQLSLEERLTTVRRSAEEMIKPSVYGQA 480 Query: 452 IILLVYVPLLTFTGVEGKMFEPMALTVILALAAAFVLSLTLVPALIAIGITGRVQEQENR 511 II+LVYVPLLTFTGVEGKMFEPMALTVI+ALAAAFVLSLTLVPALIAI ITGRVQE+EN Sbjct: 481 IIILVYVPLLTFTGVEGKMFEPMALTVIIALAAAFVLSLTLVPALIAIAITGRVQEKENI 540 Query: 512 LVAALKRCYSPLLRRAVATPMPVIAVAVVLFAAALFGFFRLGQEFIPSLDEKNIAMHALR 571 V +LK Y P L A+ PMP I +V+LF + F RLGQEFIP+LDEKNIAM ALR Sbjct: 541 FVRSLKVVYRPALALAIRRPMPFILGSVLLFVGSAVLFSRLGQEFIPTLDEKNIAMQALR 600 Query: 572 IPSTALSQSQAMQLSVEKAVSRFPQVSFVFSKTGTAEVASDPMPPNASDTFIILKPREQW 631 IPSTALSQSQ MQL VE+ VSRFPQV+ VFSKTGTAEVASDPMPPNASDTFI+LK +E+W Sbjct: 601 IPSTALSQSQDMQLEVERTVSRFPQVAHVFSKTGTAEVASDPMPPNASDTFIMLKQQEEW 660 Query: 632 PDPSLTNEQLIEDLSKAVGRLPGNVYEFTQPIQMRFNELLAGVRGDIAVKVFGDEFGPMQ 691 PDPSL +QLI+ + +AV LPGN Y FTQPIQMRFNELLAG RGD+AVKVFG+EF M Sbjct: 661 PDPSLPKDQLIKQIQEAVELLPGNNYAFTQPIQMRFNELLAGTRGDLAVKVFGEEFETMM 720 Query: 692 KAANQIAAALRGVRGATDVKVEQAGG 717 ANQIA+ LR V GA DVKVEQA G Sbjct: 721 PVANQIASILRSVEGAQDVKVEQATG 746 >ref|YP_003066996.1| cation efflux system protein czcA [Methylobacterium extorquens DM4] emb|CAX23003.1| Cation efflux system protein czcA [Methylobacterium extorquens DM4] Length = 1086 Score = 940 bits (2429), Expect = 0.0, Method: Compositional matrix adjust. Identities = 500/794 (62%), Positives = 598/794 (75%), Gaps = 31/794 (3%) Query: 1 MIERIIGLAIQRRWMVVTLAAILMFLGGLALTRLPIDAVPDITNKQVQINTVAPALSPAE 60 MI I+ ++++RW+V+ L+ + LG +LT+LPIDAVPDITN QVQ+N V P LSP + Sbjct: 1 MIHAILAFSVRQRWLVLLLSLLAAALGVFSLTKLPIDAVPDITNNQVQVNAVVPQLSPFD 60 Query: 61 IEKQITFPIETALXGRRG---SRARAR---SPATA------------SRRSRRCS----- 97 +EKQ+T+P+ETAL G G +R+ +R S TA + S R S Sbjct: 61 VEKQVTYPMETALAGIPGLEYTRSLSRNGFSQVTAVFSEATNVYFARQQVSERLSQVKDD 120 Query: 98 ---AXEPRIGPTSTGLGEIYMWTVHYS--GQKVQADGAPGLQSDGRFLTADGQMLQSEVE 152 E R+GP STGLGEIYMWTVH++ DG P QSDG +LT +GQ L+ E Sbjct: 121 LPPGAEVRMGPISTGLGEIYMWTVHFTKPAPGTVRDGQPSFQSDGTYLTPEGQRLRPGFE 180 Query: 153 KDAYLRTVQDWIIKPQIKMVPGVAGVDTIGGYLKQYQVHPDAAKLIALGLTFADVAKAIE 212 + AYLR+VQDWI+ PQ+K VPGVAGVD IGGY KQY V PD AKLIALGL+F DVA+A+E Sbjct: 181 QAAYLRSVQDWIVGPQLKTVPGVAGVDVIGGYEKQYHVQPDPAKLIALGLSFKDVAEAVE 240 Query: 213 TNNVSRGARYIERNGEGFVVRSGGRLENIDELGAVVVTTRGGVPVRIRDLATLSIGGETR 272 NN +RGA Y+ER+GEG VVRS GR+E +DE+G +VV TRGGVPVRI D+A + IG E R Sbjct: 241 QNNQNRGAGYLERSGEGVVVRSAGRIEGMDEIGRIVVATRGGVPVRISDVAEVRIGRELR 300 Query: 273 TGSASENGREVVVGTALMLIGANSRTVSAAVDAKLRTIMPSLPAGIEVKTVLDRTQLVDA 332 TGSASE+G E VVGTALMLIG NSRTVSAAVDA+L+ + SLP +EV+TVL+RT LVDA Sbjct: 301 TGSASEDGEEAVVGTALMLIGGNSRTVSAAVDARLKEVSKSLPPNVEVRTVLNRTALVDA 360 Query: 333 TIGTVARNLSEGALLVIAVLFVLLGNFRAALITALVIPVAMLMTAIGMWQGRISANLMSL 392 T+ TV++NL+EGALLVIAVLF+LLGN RAA+ITALVIPVAMLMT GM QG+ISANLMSL Sbjct: 361 TVKTVSKNLAEGALLVIAVLFLLLGNIRAAIITALVIPVAMLMTMSGMVQGKISANLMSL 420 Query: 393 GALDFGLIVDGAVIITENSLRHLAEKQQALGRVLTRDERLATVRASAVEMVQPSLYGQAI 452 GALDFGLIVDGAVII EN+LRHLAE+Q GR L+ +ERLATV+ASA EM++PS+YGQAI Sbjct: 421 GALDFGLIVDGAVIIAENTLRHLAERQTEAGRPLSLEERLATVQASAEEMIKPSVYGQAI 480 Query: 453 ILLVYVPLLTFTGVEGKMFEPMALTVILALAAAFVLSLTLVPALIAIGITGRVQEQENRL 512 I+LVYVPLLTFTGVEGKMFEPMALTVI+ALA AFVLSLT VPAL AI ITG+VQE+EN L Sbjct: 481 IILVYVPLLTFTGVEGKMFEPMALTVIIALACAFVLSLTFVPALTAIVITGKVQEKENVL 540 Query: 513 VAALKRCYSPLLRRAVATPMPVIAVAVVLFAAALFGFFRLGQEFIPSLDEKNIAMHALRI 572 + LKR Y PLL AV P PVI AV+LF A+ F RLGQEF+P LDEKNIAMHA+RI Sbjct: 541 IRGLKRAYRPLLAGAVRRPGPVIGAAVLLFLASGILFGRLGQEFMPQLDEKNIAMHAMRI 600 Query: 573 PSTALSQSQAMQLSVEKAVSRFPQVSFVFSKTGTAEVASDPMPPNASDTFIILKPREQWP 632 PST+L+QSQ MQL+VE+AVS FPQV+FVF+KTGTAE+ASDPMP N SDTFI+LKP+ +WP Sbjct: 601 PSTSLTQSQDMQLAVERAVSAFPQVAFVFAKTGTAEIASDPMPVNVSDTFIMLKPQAEWP 660 Query: 633 DPSLTNEQLIEDLSKAVGRLPGNVYEFTQPIQMRFNELLAGVRGDIAVKVFGDEFGPMQK 692 DP L+ ++LIE + V ++PGN YEFTQPIQMRFNELLAG RGD+AVKVFG+ F M Sbjct: 661 DPHLSKDELIERIQAEVNKVPGNNYEFTQPIQMRFNELLAGTRGDLAVKVFGESFEAMLP 720 Query: 693 AANQIAAALRGVRGATDVKVEQAGGXRGRRPGCRRRLRGRSQLRHRGAIAGERALRSRGA 752 AAN+IA LRGV GA DVKVEQ G + R L H A + + + Sbjct: 721 AANRIAGILRGVEGAQDVKVEQVTGLPSLEIKVDKDEIARLGLNH---FAVQDVIGAAIG 777 Query: 753 EQFAGRVAEGDAEF 766 + AG V EGD F Sbjct: 778 GREAGVVFEGDRRF 791 >ref|YP_002963702.1| Cobalt-zinc-cadmium resistance protein czcA (Cation efflux system protein czcA) [methylobacterium extorquens AM1] gb|ACS40425.1| Cobalt-zinc-cadmium resistance protein czcA (Cation efflux system protein czcA) [Methylobacterium extorquens AM1] Length = 1086 Score = 939 bits (2428), Expect = 0.0, Method: Compositional matrix adjust. Identities = 496/746 (66%), Positives = 597/746 (80%), Gaps = 29/746 (3%) Query: 1 MIERIIGLAIQRRWMVVTLAAILMFLGGLALTRLPIDAVPDITNKQVQINTVAPALSPAE 60 MI RI+ ++ +RW+V+ L+ + GG ALT+LPIDAVPDITN QVQINTVAP+LSP + Sbjct: 1 MISRILDFSVHQRWLVLLLSLLAAGFGGYALTKLPIDAVPDITNNQVQINTVAPSLSPID 60 Query: 61 IEKQITFPIETALXGRRG---SRARAR---SPATA------------SRRSRRCSA---- 98 IEKQ+T+P+ETAL G +G +R+ +R S TA + + R S Sbjct: 61 IEKQVTYPVETALAGIKGLEYTRSLSRNGFSQVTAVFAEKLDIYFARQQVAERLSQVKQD 120 Query: 99 ----XEPRIGPTSTGLGEIYMWTVHYSG---QKVQADGAPGLQSDGRFLTADGQMLQSEV 151 EPR+GP STGLGEIYMW++HY+ + V G PG Q DG +LT +GQ L++E+ Sbjct: 121 LPPDAEPRMGPISTGLGEIYMWSIHYAKPDERTVSPAGKPGWQPDGSYLTPEGQRLRTEL 180 Query: 152 EKDAYLRTVQDWIIKPQIKMVPGVAGVDTIGGYLKQYQVHPDAAKLIALGLTFADVAKAI 211 E+ AYLRTVQDWII+PQIK VPGVAGVD IGG+ KQY V PD KL AL L+F+DVA+A+ Sbjct: 181 ERAAYLRTVQDWIIRPQIKTVPGVAGVDGIGGFEKQYHVQPDPTKLTALDLSFSDVARAL 240 Query: 212 ETNNVSRGARYIERNGEGFVVRSGGRLENIDELGAVVVTTRGGVPVRIRDLATLSIGGET 271 E NN ++GARY+E NGEG+VVR+ GRLE++ E+ V+VTTRGGVPVRI+D+A + IG + Sbjct: 241 EANNANQGARYLEDNGEGYVVRAAGRLESMGEIENVLVTTRGGVPVRIKDIAEVRIGRDL 300 Query: 272 RTGSASENGREVVVGTALMLIGANSRTVSAAVDAKLRTIMPSLPAGIEVKTVLDRTQLVD 331 RTGSASE+G+EVVVGTALMLIG NSRTV+AAVDAK+ I SLP G+EV+TVL+RT LV+ Sbjct: 301 RTGSASEDGQEVVVGTALMLIGENSRTVAAAVDAKMTEIRKSLPPGVEVQTVLNRTLLVE 360 Query: 332 ATIGTVARNLSEGALLVIAVLFVLLGNFRAALITALVIPVAMLMTAIGMWQGRISANLMS 391 ATI TVA+NL+EGA LVI +LF+LLGN RAA+ITALVIPVAMLMT GM + +ISANLMS Sbjct: 361 ATIRTVAKNLAEGAALVIVILFLLLGNIRAAIITALVIPVAMLMTMTGMVEAKISANLMS 420 Query: 392 LGALDFGLIVDGAVIITENSLRHLAEKQQALGRVLTRDERLATVRASAVEMVQPSLYGQA 451 LGALDFGLIVDGAVIITEN+LRHLAEKQ LGR L +ERLATVRASA EM++PSLYGQA Sbjct: 421 LGALDFGLIVDGAVIITENALRHLAEKQHGLGRTLDTEERLATVRASAEEMIKPSLYGQA 480 Query: 452 IILLVYVPLLTFTGVEGKMFEPMALTVILALAAAFVLSLTLVPALIAIGITGRVQEQENR 511 II+LVYVPLLTFTGVEGKMFEPMALTVI+ALAAAFVLSLT VPALIAI ITGRV E++N Sbjct: 481 IIILVYVPLLTFTGVEGKMFEPMALTVIIALAAAFVLSLTFVPALIAIVITGRVTEKDNV 540 Query: 512 LVAALKRCYSPLLRRAVATPMPVIAVAVVLFAAALFGFFRLGQEFIPSLDEKNIAMHALR 571 ++ ALK Y P+L AV PM I A++L A A F RLG EFIP+LDEK+IAM+ALR Sbjct: 541 IIRALKWAYRPVLAGAVRAPMVFIVAALLLLAGAGLLFTRLGAEFIPTLDEKSIAMNALR 600 Query: 572 IPSTALSQSQAMQLSVEKAVSRFPQVSFVFSKTGTAEVASDPMPPNASDTFIILKPREQW 631 IPST+LSQSQAMQL +E+A+ RFPQV++VFSKTGTAEVASDPMP N+SDTF+ILKP+E+W Sbjct: 601 IPSTSLSQSQAMQLKIEQAIRRFPQVAYVFSKTGTAEVASDPMPQNSSDTFVILKPQEEW 660 Query: 632 PDPSLTNEQLIEDLSKAVGRLPGNVYEFTQPIQMRFNELLAGVRGDIAVKVFGDEFGPMQ 691 PDP L+ +L E + KAVG L GNV+EF+QPIQ+RFNELLAG RGD+AVKVFG+EFGPM Sbjct: 661 PDPDLSKAELQEKIEKAVGALAGNVFEFSQPIQLRFNELLAGARGDLAVKVFGEEFGPMT 720 Query: 692 KAANQIAAALRGVRGATDVKVEQAGG 717 KAA+QIA LRG+ GA DVKVEQ G Sbjct: 721 KAADQIAEILRGIDGAEDVKVEQTAG 746 >ref|YP_001926736.1| heavy metal efflux pump, CzcA family [Methylobacterium populi BJ001] gb|ACB82201.1| heavy metal efflux pump, CzcA family [Methylobacterium populi BJ001] Length = 1082 Score = 936 bits (2419), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/746 (65%), Positives = 589/746 (78%), Gaps = 29/746 (3%) Query: 1 MIERIIGLAIQRRWMVVTLAAILMFLGGLALTRLPIDAVPDITNKQVQINTVAPALSPAE 60 MI +I+ ++ +RW+V+ L+ + GG A+T+LPIDAVPDITN QVQINT AP+LSP + Sbjct: 1 MISKILDFSVHQRWLVLLLSLLAAGFGGYAVTKLPIDAVPDITNNQVQINTTAPSLSPVD 60 Query: 61 IEKQITFPIETALXGRRG---SRARAR---SPATA------------SRRSRRCS----- 97 IEKQ+T+P+ETAL G +G +R+ +R S TA + + R S Sbjct: 61 IEKQVTYPVETALAGIKGLEYTRSLSRNGFSQVTAVFAEKLDIYFARQQVAERLSQVKQD 120 Query: 98 ---AXEPRIGPTSTGLGEIYMWTVHYSG---QKVQADGAPGLQSDGRFLTADGQMLQSEV 151 EP +GP STGLGEIYMW++HY+ ++V A G PG Q DG +LT +GQ L++E+ Sbjct: 121 LPPGAEPAMGPISTGLGEIYMWSIHYAKPGERQVSAAGKPGWQPDGSYLTPEGQSLRTEL 180 Query: 152 EKDAYLRTVQDWIIKPQIKMVPGVAGVDTIGGYLKQYQVHPDAAKLIALGLTFADVAKAI 211 E+ AYLRTVQDWII+PQIK VPGVAG+D IGG+ KQY V PD KL A L+F DVA+A+ Sbjct: 181 EQTAYLRTVQDWIIRPQIKTVPGVAGIDGIGGFEKQYHVQPDPTKLAARDLSFGDVARAL 240 Query: 212 ETNNVSRGARYIERNGEGFVVRSGGRLENIDELGAVVVTTRGGVPVRIRDLATLSIGGET 271 ETNN ++GARY+E NGEG+VVR+ GRLE++DE+G VVV TR GVPVRIRD+A + IG + Sbjct: 241 ETNNANQGARYLEDNGEGYVVRAAGRLESMDEIGDVVVATRAGVPVRIRDIAEVRIGKDL 300 Query: 272 RTGSASENGREVVVGTALMLIGANSRTVSAAVDAKLRTIMPSLPAGIEVKTVLDRTQLVD 331 RTGS SENG+EVV+GTALMLIG NSR V+AAVDA++ I SLP G+EV+TVLDRT+LV+ Sbjct: 301 RTGSGSENGQEVVIGTALMLIGDNSRKVAAAVDARMEQIRKSLPPGVEVQTVLDRTRLVE 360 Query: 332 ATIGTVARNLSEGALLVIAVLFVLLGNFRAALITALVIPVAMLMTAIGMWQGRISANLMS 391 ATI TVA+NLSEGA LVI +LF+LLGN RAA+ITALVIPVAMLMT GM + +ISANLMS Sbjct: 361 ATIKTVAKNLSEGAALVIVILFLLLGNIRAAIITALVIPVAMLMTMTGMVEAKISANLMS 420 Query: 392 LGALDFGLIVDGAVIITENSLRHLAEKQQALGRVLTRDERLATVRASAVEMVQPSLYGQA 451 LGALDFGLIVDGAVIITEN+LRHLAEKQ LGR L +ERL TVRASA EM++PSLYGQA Sbjct: 421 LGALDFGLIVDGAVIITENALRHLAEKQHELGRSLDTEERLQTVRASAEEMIKPSLYGQA 480 Query: 452 IILLVYVPLLTFTGVEGKMFEPMALTVILALAAAFVLSLTLVPALIAIGITGRVQEQENR 511 II+LVYVPLLTFTGVEGKMFEPMALTVI+AL AAFVLSLT VPALI+I ITG+V E++N Sbjct: 481 IIILVYVPLLTFTGVEGKMFEPMALTVIIALVAAFVLSLTFVPALISIVITGKVTEEDNF 540 Query: 512 LVAALKRCYSPLLRRAVATPMPVIAVAVVLFAAALFGFFRLGQEFIPSLDEKNIAMHALR 571 ++ A K Y P+L AV P+ + A++L A RLG EFIP LDEK+IA++A R Sbjct: 541 IIRAFKAAYRPVLAAAVRAPVAFVVGALLLLVGAGILSTRLGTEFIPQLDEKSIALNATR 600 Query: 572 IPSTALSQSQAMQLSVEKAVSRFPQVSFVFSKTGTAEVASDPMPPNASDTFIILKPREQW 631 IPST+L+QSQAMQL VE+AVS+FPQV++VFSKTGTAEVASDPMPPN+SDTF+ILKP+E+W Sbjct: 601 IPSTSLTQSQAMQLKVEQAVSKFPQVAYVFSKTGTAEVASDPMPPNSSDTFVILKPQEEW 660 Query: 632 PDPSLTNEQLIEDLSKAVGRLPGNVYEFTQPIQMRFNELLAGVRGDIAVKVFGDEFGPMQ 691 PDPSL+ L E + KAVG L GNVYEF+QPIQ+RFNELLAG RGD+AVKVFG+EF PM Sbjct: 661 PDPSLSKADLQEQIEKAVGELAGNVYEFSQPIQLRFNELLAGTRGDLAVKVFGEEFEPML 720 Query: 692 KAANQIAAALRGVRGATDVKVEQAGG 717 KAANQ+A LRG+ GA DVKVEQ G Sbjct: 721 KAANQVAQVLRGITGAEDVKVEQTAG 746