BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0243.0020.p (210 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_769547.1| transcriptional regulator [Bradyrhizobium japon... 287 6e-76 ref|ZP_06839079.1| transcriptional regulator, TetR family [Burkh... 117 2e-24 ref|ZP_08204036.1| regulatory protein TetR [Gordonia neofelifaec... 102 3e-20 ref|ZP_08644979.1| transcriptional regulator TetR [Acetobacter t... 102 4e-20 ref|ZP_04706708.1| TetR family transcriptional regulator [Strept... 99 3e-19 >ref|NP_769547.1| transcriptional regulator [Bradyrhizobium japonicum USDA 110] dbj|BAC48172.1| transcriptional regulatory protein [Bradyrhizobium japonicum USDA 110] Length = 215 Score = 287 bits (735), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 146/207 (70%), Positives = 170/207 (82%) Query: 3 QIVRKPFKTYHHGDLREALIQAALGEVELGGPEAISIKALAKQLGVSQPAPYRHFADREA 62 Q+ RKP TYHHGDLR+ALI+AAL E E GG EAISIKALAKQLGVSQPAPYRHFADREA Sbjct: 4 QLARKPENTYHHGDLRDALIKAALREAEQGGAEAISIKALAKQLGVSQPAPYRHFADREA 63 Query: 63 LLEAVTAEAFRQFNVIMREAIEQSGKGSKLSRFAQAALAFGLERHGIYRLMFASRTMACA 122 LL AVTAEAFRQ + ++REA+ + K SKLS+ AQA L FGL R+GIYRLMFASRT++CA Sbjct: 64 LLAAVTAEAFRQLSAMLREAMAKPSKQSKLSKLAQATLDFGLRRNGIYRLMFASRTVSCA 123 Query: 123 PKGSELHTAAMETLALLIESFEAPAVGLLRERQALKIWAGLHGIVMLAEQGLLTGESAQI 182 KGSELH A ETL L+IE+ E+PAVG LRERQALKIWA +HG+VMLAEQGLLTGE A Sbjct: 124 AKGSELHEATRETLGLVIEALESPAVGYLRERQALKIWAAVHGVVMLAEQGLLTGEPAHA 183 Query: 183 SREELLDEIVEQTKAALTVALQATEDR 209 +REEL+++ V +TKAAL A++ R Sbjct: 184 TREELVEDFVSETKAALAAAIKGARRR 210 >ref|ZP_06839079.1| transcriptional regulator, TetR family [Burkholderia sp. Ch1-1] gb|EFG73525.1| transcriptional regulator, TetR family [Burkholderia sp. Ch1-1] Length = 195 Score = 117 bits (292), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 74/172 (43%), Positives = 99/172 (57%), Gaps = 11/172 (6%) Query: 10 KTYHHGDLREALIQAALGEVELGGPEAISIKALAKQLGVSQPAPYRHFADREALLEAVTA 69 K+YHHGDLR AL+ AA E+ G +++++ +LA++ GV+Q APYRHFADR+ LL AV Sbjct: 18 KSYHHGDLRRALLDAAREEIAANGAQSLTLASLARRAGVAQSAPYRHFADRDDLLFAVGE 77 Query: 70 EAFRQFNVIMREAIEQSGKGSKLSRFAQAALAFGLERHGIYRLMFASRTMACAPKGSELH 129 E FR+ + + A E G+ + R A A L FG YRLMFASR + A + S L Sbjct: 78 EGFRELSAALSSAAESGGEEGYVRRMAAAYLQFGERNVERYRLMFASRLVPDALQDSPLS 137 Query: 130 TAAMETLALLIESFEAPAVGLLRER-----QALKIWAGLHGIVMLAEQGLLT 176 AA E+ LL+ A R R A +WA LHG+VML G +T Sbjct: 138 KAAKESYDLLLAGISA------RGRSGPYGSATAVWAQLHGLVMLKADGFVT 183 >ref|ZP_08204036.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] gb|EGD56256.1| regulatory protein TetR [Gordonia neofelifaecis NRRL B-59395] Length = 195 Score = 102 bits (254), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 64/179 (35%), Positives = 94/179 (52%), Gaps = 6/179 (3%) Query: 8 PFKTYHHGDLREALIQAALGEVELGGPEAISIKALAKQLGVSQPAPYRHFADREALLEAV 67 P TYHHGDL AL+ AA+ +E G +S++A+A++ GVS APYRHF DR ALL AV Sbjct: 6 PVATYHHGDLPTALVVAAIELLEEDGAGDLSLRAVARRAGVSTAAPYRHFPDRTALLSAV 65 Query: 68 TAEAFRQFNVIMREAIEQSGKGSKLSRFAQAALAFGLERHGIYRLMFASRTMACAPKGSE 127 A + + + EA L+ A A + F L+R G++R+MFA +P Sbjct: 66 AAVGYTELGAALVEASPDPADADDLAEVAVAYVRFALDRPGLFRVMFAEGCDRTSPD--- 122 Query: 128 LHTAAMETLALLIESFEAPAVG-LLRERQALKIWAGLHGIVMLAEQGLL-TGESAQISR 184 AA+ET+ + + A + +E A +WA +HG+ L G L T ++R Sbjct: 123 -RVAAVETIRAYLAAIVANTMPEAEQEAMATSVWALVHGLAFLHLDGKLGTSPDDDVAR 180 >ref|ZP_08644979.1| transcriptional regulator TetR [Acetobacter tropicalis NBRC 101654] dbj|GAA08283.1| transcriptional regulator TetR [Acetobacter tropicalis NBRC 101654] Length = 202 Score = 102 bits (254), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 79/220 (35%), Positives = 107/220 (48%), Gaps = 36/220 (16%) Query: 1 MGQIVRKPFKTYHHGDLREALIQAALGEVELGGPEAISIKALAKQLGVSQPAPYRHFADR 60 M I +P YHHGDLR ALI+ AL + A +++ +A++ GVS APY+HF D+ Sbjct: 1 MSDIKERP---YHHGDLRRALIETALAMLATDQNWAFTLREVARRTGVSHAAPYKHFRDK 57 Query: 61 EALLEAVTAEAFRQFNVIMREAIEQSGKGSKLSRF---AQAALAFGLERHGIYRLMFASR 117 E LL + F + M EA+ S +G+ +F AQA + F L G+YRLMF+S Sbjct: 58 EVLLRELARIGFERLGQAMAEAM-ASARGAMRGKFVAGAQACIEFALHNPGLYRLMFSSD 116 Query: 118 TMACAPKGSELHTAAMETLALLIE---------SFEAPAVGLLRERQALKIWAGLHGIVM 168 A LH AAM T +L+ SF A+ L A WA +HG+ M Sbjct: 117 ADKAA--DPNLHDAAMNTFGILLRLLEEGQRSGSFRPVAINAL----AAASWAQVHGLAM 170 Query: 169 LAEQGLLTGESAQISREELLDEIV--EQTKAALTVALQAT 206 LA G +LL+E V E +AAL V L Sbjct: 171 LAING------------QLLEEKVGPEPIRAALDVLLDGV 198 >ref|ZP_04706708.1| TetR family transcriptional regulator [Streptomyces roseosporus NRRL 11379] ref|ZP_06582375.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 15998] gb|EFE72836.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 15998] Length = 204 Score = 99.4 bits (246), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 63/175 (36%), Positives = 92/175 (52%), Gaps = 7/175 (4%) Query: 10 KTYHHGDLREALIQAALGEVELGGPEAISIKALAKQLGVSQPAPYRHFADREALLEAVTA 69 TYHHGDLR A ++AA +E G +S++A+A++ GVS APYRH+ADREAL+ AV A Sbjct: 5 STYHHGDLRAACLRAARELLEEDGSAGLSLRAVARRAGVSATAPYRHYADREALVSAVAA 64 Query: 70 EAFRQFNVIMREAIEQSGKGSKLSRFAQAALAFGLERHGIYRLMFASRTMACAPKGSE-- 127 E +R+ + +A +L+ A A + F LE ++R MFA C P E Sbjct: 65 EGYRELATHLAQAHPAPSTPDELAAVAVAYVQFALEHPALFRAMFAE---PCDPTSEERV 121 Query: 128 LHTAAMETLALLIESFEAPAVGLLRERQALKIWAGLHGIVMLAEQGLLTGESAQI 182 TAA+ I + P G+ + +WA +HG+ L G L + +I Sbjct: 122 AATAAISEYVRTIVAATFP--GVDANALSTTVWALVHGLAFLHLDGKLDSSTPEI 174