BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0235.0002.p (375 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001207954.1| putative adenylate cyclase [Bradyrhizobium s... 146 5e-33 ref|YP_298787.1| adenylyl cyclase class-3/4/guanylyl cyclase [Ra... 80 6e-13 ref|YP_004688339.1| adenylate cyclase family protein [Cupriavidu... 79 2e-12 ref|YP_004688095.1| ATP synthase beta subunit/transription termi... 76 8e-12 ref|YP_366416.1| adenylate/guanylate cyclase [Burkholderia sp. 3... 75 2e-11 >ref|YP_001207954.1| putative adenylate cyclase [Bradyrhizobium sp. ORS 278] emb|CAL79739.1| putative Adenylate cyclase [Bradyrhizobium sp. ORS 278] Length = 1076 Score = 146 bits (369), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 68/102 (66%), Positives = 82/102 (80%) Query: 1 VNGPSSRFCGRCGTALAAGSVRPDAPSQRLLRSLSTKGGERKNLTLLFADIRNSTNLIDS 60 N PS+RFCG+CG L+ D +QR+LR+LS+KGGERK LT+LFADIR+ST LIDS Sbjct: 34 TNSPSNRFCGQCGAPLSGRLAPSDQSAQRVLRTLSSKGGERKRLTILFADIRDSTQLIDS 93 Query: 61 LGDPELGMRRLEPVLDLMKEAVHRYDGIVNKIQGDGVXEQLG 102 LGDPEL M+RL+PVL+LMKEAVHR+DG+VNK QGDGV G Sbjct: 94 LGDPELAMQRLDPVLNLMKEAVHRFDGVVNKTQGDGVMALFG 135 Score = 68.2 bits (165), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 29/37 (78%), Positives = 34/37 (91%) Query: 335 LADPGMQIRVGLHTGEVVVQTVENTIYQTYDAAGANV 371 L DP +Q+RVGLHTGEV+VQ VEN++YQTYDAAGANV Sbjct: 161 LGDPHLQVRVGLHTGEVIVQVVENSMYQTYDAAGANV 197 >ref|YP_298787.1| adenylyl cyclase class-3/4/guanylyl cyclase [Ralstonia eutropha JMP134] gb|AAZ63943.1| Adenylyl cyclase class-3/4/guanylyl cyclase:Tetratricopeptide TPR_4 [Ralstonia eutropha JMP134] Length = 1141 Score = 80.1 bits (196), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 62/170 (36%), Positives = 77/170 (45%), Gaps = 42/170 (24%) Query: 4 PSSRFCGRCGTALA-----AGSVRPDA--------PSQRLLRSLSTKG---------GER 41 P RFC CGT+L + V+P A PS + R L+ + GER Sbjct: 37 PEDRFCAECGTSLVPAMEPSAEVQPAAVRAPIHYTPSHLVDRILAEQAAMEARGASAGER 96 Query: 42 KNLTLLFADIRNSTNLIDSLGDPELGMRRLEPVLDLMKEAVHRYDGIVNKIQGDGVXEQL 101 K +T LFAD+ ST LI L DPE R ++PV+DLM EAVH Y+G V K GDG+ Sbjct: 97 KTITALFADMAGSTALIHDL-DPEEARRLIDPVIDLMMEAVHHYEGYVAKSLGDGILALF 155 Query: 102 GIDPLVLERVLADNPRRQPLDRRRHAGRAEALVIFAPADQPVRRRHLDEV 151 G P+ HA RA + A Q RRH D V Sbjct: 156 G----------------APIAHEDHAHRA---LYAALRMQAAMRRHSDRV 186 Score = 38.1 bits (87), Expect = 2.2, Method: Compositional matrix adjust. Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 13/116 (11%) Query: 264 LRPEQRRALAFEGLAAALEAHQHV-----GQLGDRVGSAVG--IEHDDVGGIADRDAVIL 316 L PE+ R L + +EA H LGD + + G I H+D A A+ + Sbjct: 116 LDPEEARRLIDPVIDLMMEAVHHYEGYVAKSLGDGILALFGAPIAHEDHAHRALYAALRM 175 Query: 317 EVHQPRRQVGDEIEAGVELADPGMQIRVGLHTGEVVVQTVENTIYQT-YDAAGANV 371 + R +E G+ L QIRVG+HTGEVVV+++ +T YD G + Sbjct: 176 QAAMRRHSDRVRLEQGIPL-----QIRVGIHTGEVVVRSIRKDDLRTDYDPVGHTI 226 >ref|YP_004688339.1| adenylate cyclase family protein [Cupriavidus necator N-1] gb|AEI82301.1| adenylate cyclase family protein [Cupriavidus necator N-1] Length = 1129 Score = 78.6 bits (192), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 48/130 (36%), Positives = 69/130 (53%), Gaps = 21/130 (16%) Query: 4 PSSRFCGRCGTALAAGSVRPDA-PSQRLLRSLSTK--------------GGERKNLTLLF 48 P++RFC CG ++ + P A P+Q R L+ + GERK +T+LF Sbjct: 38 PTARFCNACGATVSEFPIGPSATPAQYTPRHLAERIRAEQAALEARGMASGERKTITVLF 97 Query: 49 ADIRNSTNLIDSLGDPELGMRRLEPVLDLMKEAVHRYDGIVNKIQGDGVXEQLGIDPLVL 108 AD+ ST LI DPE + + PV+++M EAVH Y+G V K GDG+ G P+ Sbjct: 98 ADMAGSTALIHDW-DPEAALHLISPVIEMMMEAVHYYEGYVAKSLGDGILALFGA-PIAH 155 Query: 109 ERVLADNPRR 118 E D+P+R Sbjct: 156 E----DHPQR 161 >ref|YP_004688095.1| ATP synthase beta subunit/transription termination factor rho [Cupriavidus necator N-1] gb|AEI82057.1| ATP synthase beta subunit/transription termination factor rho [Cupriavidus necator N-1] Length = 1140 Score = 76.3 bits (186), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 51/129 (39%), Positives = 71/129 (55%), Gaps = 21/129 (16%) Query: 5 SSRFCGRCGTAL-------AAGSVR--PDAPSQRL------LRSLSTKGGERKNLTLLFA 49 ++RFC CGT + +AG +R P ++R+ L + GGERK +T+LFA Sbjct: 39 TARFCNACGTPVGELPQESSAGPIRYTPSHLAERIRAEQAALEARGDAGGERKTITVLFA 98 Query: 50 DIRNSTNLIDSLGDPELGMRRLEPVLDLMKEAVHRYDGIVNKIQGDGVXEQLGIDPLVLE 109 D+ ST LI DPE R + PV++LM EAVH Y+G V K GDG+ G P+ E Sbjct: 99 DMAGSTALIHD-RDPEDAHRLITPVIELMMEAVHYYEGYVAKSLGDGILALFGA-PIAHE 156 Query: 110 RVLADNPRR 118 D+P+R Sbjct: 157 ----DHPKR 161 Score = 37.4 bits (85), Expect = 3.7, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 8/85 (9%) Query: 290 LGDRVGSAVG--IEHDDVGGIADRDAVILEVHQPRRQVGDEIEAGVELADPGMQIRVGLH 347 LGD + + G I H+D A A+ ++ R +E GV L QIRVG+H Sbjct: 141 LGDGILALFGAPIAHEDHPKRALYAALRMQEAMQRHSDKLRLEQGVSL-----QIRVGIH 195 Query: 348 TGEVVVQTV-ENTIYQTYDAAGANV 371 TGEVVV+++ ++ ++ YD G + Sbjct: 196 TGEVVVRSIRKDDLHTDYDPVGHTI 220 >ref|YP_366416.1| adenylate/guanylate cyclase [Burkholderia sp. 383] gb|ABB05772.1| adenylate/guanylate cyclase [Burkholderia sp. 383] Length = 1148 Score = 75.1 bits (183), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 47/125 (37%), Positives = 62/125 (49%), Gaps = 26/125 (20%) Query: 3 GPSSRFCGRCGTALAAGS-------------------VRPDAPSQRL------LRSLSTK 37 P +RFC CGT LAA + PD ++R+ + + Sbjct: 36 APVARFCSNCGTPLAAPTAASPPSRPSGREPPPTPVHYTPDHLAERIRAEHAAMAARGEP 95 Query: 38 GGERKNLTLLFADIRNSTNLIDSLGDPELGMRRLEPVLDLMKEAVHRYDGIVNKIQGDGV 97 GERK +T LFAD+ ST LI L DPE+ R + PV++LM EAVH Y+G V K GDG+ Sbjct: 96 AGERKTVTALFADMAGSTALIHDL-DPEVAHRLIVPVVELMMEAVHYYEGYVAKSLGDGI 154 Query: 98 XEQLG 102 G Sbjct: 155 LALFG 159 Score = 38.9 bits (89), Expect = 1.4, Method: Compositional matrix adjust. Identities = 33/87 (37%), Positives = 47/87 (54%), Gaps = 12/87 (13%) Query: 290 LGDRVGSAVG--IEHDDVGGIADRDAVILEVHQPRRQVGDEI--EAGVELADPGMQIRVG 345 LGD + + G I H+D A A L + Q RQ GD I + G+ L QIRVG Sbjct: 150 LGDGILALFGAPIAHEDHAQRALFAA--LRMQQAMRQHGDRIRLQEGIPL-----QIRVG 202 Query: 346 LHTGEVVVQTV-ENTIYQTYDAAGANV 371 +HTGEVVV+++ + ++ YD G + Sbjct: 203 VHTGEVVVRSIRTDDLHTEYDPLGHTI 229