BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0219.0002.p (304 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_768059.1| 5,10-methylenetetrahydrofolate reductase [Brady... 545 e-153 ref|YP_001242849.1| 5,10-methylenetetrahydrofolate reductase [Br... 525 e-147 ref|YP_001203147.1| 5,10-methylenetetrahydrofolate reductase [Br... 521 e-146 ref|YP_575720.1| 5,10-methylenetetrahydrofolate reductase [Nitro... 519 e-145 ref|ZP_01044512.1| 5,10-methylenetetrahydrofolate reductase [Nit... 509 e-142 >ref|NP_768059.1| 5,10-methylenetetrahydrofolate reductase [Bradyrhizobium japonicum USDA 110] dbj|BAC46684.1| 5,10-methylenetetrahydrofolate reductase [Bradyrhizobium japonicum USDA 110] Length = 307 Score = 545 bits (1404), Expect = e-153, Method: Compositional matrix adjust. Identities = 262/289 (90%), Positives = 272/289 (94%) Query: 16 KAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGSTRERTHSTITRILRE 75 K P ISFEFFPPKTEEMERNLWETINRLAPL P FVSVTYGAGGSTRERTHSTI RIL+E Sbjct: 19 KRPAISFEFFPPKTEEMERNLWETINRLAPLDPKFVSVTYGAGGSTRERTHSTIARILKE 78 Query: 76 TDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGIGTPYFTHPDGYQSSA 135 T LLPAAHLTCV ASRGEID+IVDRYHEVGVRHIV LRGDPPGGIGTPY +HPDGYQSSA Sbjct: 79 TALLPAAHLTCVGASRGEIDEIVDRYHEVGVRHIVGLRGDPPGGIGTPYSSHPDGYQSSA 138 Query: 136 ELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGATRAITQVFFDNDLYH 195 +LVAGIK+RH DIE+SVSAYPEKHPEA+DFDADIDTLKAKVDAGATRAITQVFFDNDLY Sbjct: 139 DLVAGIKKRHGDIEVSVSAYPEKHPEARDFDADIDTLKAKVDAGATRAITQVFFDNDLYF 198 Query: 196 RYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAEKFEGLDNDAETRKLV 255 RY+DRVRARGI IP+VPGIMPMHNFKQAR FVTRAGTSVPDWLAEKFEGLD+DAETRKLV Sbjct: 199 RYLDRVRARGINIPVVPGIMPMHNFKQARAFVTRAGTSVPDWLAEKFEGLDDDAETRKLV 258 Query: 256 AATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGAQKAA 304 AATVAAGQVQKL KHGVDTFHFYTMNRADLVFAISHLLGIR AQKAA Sbjct: 259 AATVAAGQVQKLAKHGVDTFHFYTMNRADLVFAISHLLGIRAKSAQKAA 307 >ref|YP_001242849.1| 5,10-methylenetetrahydrofolate reductase [Bradyrhizobium sp. BTAi1] gb|ABQ38943.1| 5,10-methylenetetrahydrofolate reductase [Bradyrhizobium sp. BTAi1] Length = 305 Score = 525 bits (1352), Expect = e-147, Method: Compositional matrix adjust. Identities = 253/304 (83%), Positives = 275/304 (90%) Query: 1 MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS 60 MT+ +++ + A PKISFEFFPPKTEEMER LW +I RLAPL P+FVSVTYGAGGS Sbjct: 1 MTDLATAITDGHAAIIRPKISFEFFPPKTEEMERTLWTSIERLAPLEPSFVSVTYGAGGS 60 Query: 61 TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI 120 TRERTH+TI RIL+ET LLPAAHLTCV ASR EID++VDRYHEVGVRHIVALRGDPPGGI Sbjct: 61 TRERTHATIARILKETALLPAAHLTCVGASRHEIDEVVDRYHEVGVRHIVALRGDPPGGI 120 Query: 121 GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA 180 GTPY+TH +GYQSS EL+AGIK+RH DIEISVSAYPEKHPE++DFDADID LKAKVDAGA Sbjct: 121 GTPYYTHAEGYQSSPELIAGIKKRHPDIEISVSAYPEKHPESRDFDADIDMLKAKVDAGA 180 Query: 181 TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE 240 TRAITQVFFDNDLY RY+DRVRARGI+IPIVPGIMPMHNFKQAR FVTRAGT+VPDWLAE Sbjct: 181 TRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPDWLAE 240 Query: 241 KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA 300 KF+GLD+D ETRKLVAATVAAGQV KL KHGVDTFHFYTMNRADLVFAISHLLGIRP A Sbjct: 241 KFDGLDDDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSA 300 Query: 301 QKAA 304 KAA Sbjct: 301 NKAA 304 >ref|YP_001203147.1| 5,10-methylenetetrahydrofolate reductase [Bradyrhizobium sp. ORS 278] emb|CAL74910.1| 5,10-methylenetetrahydrofolate reductase [Bradyrhizobium sp. ORS 278] Length = 305 Score = 521 bits (1341), Expect = e-146, Method: Compositional matrix adjust. Identities = 250/304 (82%), Positives = 272/304 (89%) Query: 1 MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS 60 MT+ ++V + A PKISFEFFPPKTEEM+R LW +I RLAPL P+FVSVTYGAGGS Sbjct: 1 MTDLATAVTDGHSAIIRPKISFEFFPPKTEEMDRTLWSSIERLAPLEPSFVSVTYGAGGS 60 Query: 61 TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI 120 TRERTH+TI RIL+ET LLPAAHLTCV ASR EID++VDRYHEVGVRHIVALRGDPPGGI Sbjct: 61 TRERTHATIARILKETALLPAAHLTCVGASRQEIDEVVDRYHEVGVRHIVALRGDPPGGI 120 Query: 121 GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA 180 GTPY TH +GYQ+S EL+AGIK+RH D+EISVSAYPEKHPE++DFDADID LKAKVDAGA Sbjct: 121 GTPYHTHAEGYQTSPELIAGIKKRHPDVEISVSAYPEKHPESRDFDADIDMLKAKVDAGA 180 Query: 181 TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE 240 TRAITQVFFDNDLY RY+DRVRARGI+IPIVPGIMPMHNFKQAR FVTRAGT+VPDWLAE Sbjct: 181 TRAITQVFFDNDLYFRYLDRVRARGIDIPIVPGIMPMHNFKQARGFVTRAGTTVPDWLAE 240 Query: 241 KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA 300 KF+GLDND ETRKLVAATVAAGQV KL KHGVDTFHFYTMNRADLVFAISHLLGIRP Sbjct: 241 KFDGLDNDPETRKLVAATVAAGQVHKLAKHGVDTFHFYTMNRADLVFAISHLLGIRPKSV 300 Query: 301 QKAA 304 K A Sbjct: 301 NKVA 304 >ref|YP_575720.1| 5,10-methylenetetrahydrofolate reductase [Nitrobacter hamburgensis X14] gb|ABE61260.1| 5,10-methylenetetrahydrofolate reductase [Nitrobacter hamburgensis X14] Length = 304 Score = 519 bits (1336), Expect = e-145, Method: Compositional matrix adjust. Identities = 249/304 (81%), Positives = 271/304 (89%) Query: 1 MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS 60 MT+ + V N P A K P ISFEFFPPKTEEMERNLW+TI RL PL PNFVSVTYGAGGS Sbjct: 1 MTDASAPVHNGPAAQKRPAISFEFFPPKTEEMERNLWDTITRLTPLAPNFVSVTYGAGGS 60 Query: 61 TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI 120 TRERTHSTI RIL ET+L PAAHLTCV A+RGEID+IV RYH++GVRHIVALRGDPPGGI Sbjct: 61 TRERTHSTIARILSETELRPAAHLTCVGAARGEIDEIVSRYHDIGVRHIVALRGDPPGGI 120 Query: 121 GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA 180 GT Y THPDGY+SSA+LVAGIKR++ DIE+SVSAYPEKHPE++D DADID LKAKVDAGA Sbjct: 121 GTAYSTHPDGYRSSADLVAGIKRQYGDIEVSVSAYPEKHPESRDIDADIDVLKAKVDAGA 180 Query: 181 TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE 240 RAITQVFFDNDLY RY+DRVRARGI IPIVPGIMPMHNF+QAR FVT+AGT+VP WLAE Sbjct: 181 ARAITQVFFDNDLYLRYLDRVRARGIFIPIVPGIMPMHNFRQARAFVTKAGTTVPSWLAE 240 Query: 241 KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA 300 KFEGLD+D ETRKLVAATVAAGQVQKL K GVDTFHFYTMNRADLVF + HLLGIRP+ A Sbjct: 241 KFEGLDDDPETRKLVAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFTVCHLLGIRPDAA 300 Query: 301 QKAA 304 QKAA Sbjct: 301 QKAA 304 >ref|ZP_01044512.1| 5,10-methylenetetrahydrofolate reductase [Nitrobacter sp. Nb-311A] gb|EAQ37293.1| 5,10-methylenetetrahydrofolate reductase [Nitrobacter sp. Nb-311A] Length = 304 Score = 509 bits (1312), Expect = e-142, Method: Compositional matrix adjust. Identities = 249/304 (81%), Positives = 266/304 (87%) Query: 1 MTETISSVPNAPRAPKAPKISFEFFPPKTEEMERNLWETINRLAPLTPNFVSVTYGAGGS 60 MT+ + N P A K P ISFEFFPPKTEEMER+LW TI RLAPL P+FVSVTYGAGGS Sbjct: 1 MTDAFAPAHNDPGARKRPTISFEFFPPKTEEMERSLWSTITRLAPLDPSFVSVTYGAGGS 60 Query: 61 TRERTHSTITRILRETDLLPAAHLTCVSASRGEIDDIVDRYHEVGVRHIVALRGDPPGGI 120 TRERTHSTI RIL ET L PAAHLTCV A RGEID+IV RY ++GVRHIVALRGDPPGGI Sbjct: 61 TRERTHSTIARILSETRLRPAAHLTCVGAPRGEIDEIVSRYRDIGVRHIVALRGDPPGGI 120 Query: 121 GTPYFTHPDGYQSSAELVAGIKRRHADIEISVSAYPEKHPEAKDFDADIDTLKAKVDAGA 180 GT Y THP+GY+SS +LVAGIKRRH DIEISVSAYPEKHPE+ D D DID LKAKVDAGA Sbjct: 121 GTAYSTHPEGYRSSTDLVAGIKRRHGDIEISVSAYPEKHPESPDIDTDIDILKAKVDAGA 180 Query: 181 TRAITQVFFDNDLYHRYVDRVRARGIEIPIVPGIMPMHNFKQARNFVTRAGTSVPDWLAE 240 TRAITQVFFDNDLY RY+DRVRARGIEIPIVPGIMPMHNFKQAR FVTRAGT+VP WLAE Sbjct: 181 TRAITQVFFDNDLYLRYLDRVRARGIEIPIVPGIMPMHNFKQARTFVTRAGTTVPAWLAE 240 Query: 241 KFEGLDNDAETRKLVAATVAAGQVQKLFKHGVDTFHFYTMNRADLVFAISHLLGIRPNGA 300 KF+GLD D ETRKL+AATVAAGQVQKL K GVDTFHFYTMNRADLVFAI HLLGIRP+ A Sbjct: 241 KFDGLDEDPETRKLIAATVAAGQVQKLAKRGVDTFHFYTMNRADLVFAICHLLGIRPDAA 300 Query: 301 QKAA 304 +KAA Sbjct: 301 RKAA 304