BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0218.0044.p (416 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|NP_769504.1| two-component response regulator [Bradyrhizobiu... 665 0.0 ref|YP_001772050.1| adenylate/guanylate cyclase [Methylobacteriu... 571 e-160 ref|YP_001769663.1| adenylate/guanylate cyclase [Methylobacteriu... 570 e-160 ref|YP_001758285.1| adenylate/guanylate cyclase [Methylobacteriu... 553 e-155 ref|ZP_03502865.1| adenylate/guanylate cyclase [Rhizobium etli K... 440 e-121 >ref|NP_769504.1| two-component response regulator [Bradyrhizobium japonicum USDA 110] dbj|BAC48129.1| two-component response regulator [Bradyrhizobium japonicum USDA 110] Length = 415 Score = 665 bits (1716), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/415 (78%), Positives = 372/415 (89%), Gaps = 1/415 (0%) Query: 1 MTATILVVDDEPDLEALVLQKFRRQIRDGQVSFVFAHDGLEALQSIEAHPDVDLVVSDIN 60 MTATIL VDDEPDLEAL+LQKFRRQIRDG ++ +FA DGLEALQ++E +P VD+VVSDIN Sbjct: 1 MTATILFVDDEPDLEALILQKFRRQIRDGLLTLMFARDGLEALQALEQNPHVDMVVSDIN 60 Query: 61 MPRMDGLSLLAKLQEAEEKKSTIIVSAYGDMSNIRTAMNRGAFDFLTKPIDFADLETTIQ 120 MPRMDGLSLLAKLQEAE+KKSTIIVSAYGDMSNIR AMNRGAFDFLTKPIDFADLE TIQ Sbjct: 61 MPRMDGLSLLAKLQEAEDKKSTIIVSAYGDMSNIRIAMNRGAFDFLTKPIDFADLEATIQ 120 Query: 121 KTIRHIDMLREARRRQVEAERAHASLSRYFSPELAKRLATGGDGNDMQVHWRDVAVIFTD 180 KTI H++MLRE RRRQ+EAERAHASLSR+FSPE+A+RLA +G+ M+V WRDVA +FTD Sbjct: 121 KTIGHVEMLREVRRRQMEAERAHASLSRFFSPEIARRLAADVEGS-MEVQWRDVATLFTD 179 Query: 181 ITGFTSLVETAAPEVLAELLNEYVGGLTDVVFAHEGTVAKVIGDAIQVLFNAPGEQADYA 240 ITGFTSLVE+AAP+ L ELLNEYVGG+T++VFAHEGTVAK+IGDAIQVLFNAPG+Q DYA Sbjct: 180 ITGFTSLVESAAPQTLGELLNEYVGGMTEIVFAHEGTVAKIIGDAIQVLFNAPGDQLDYA 239 Query: 241 NRAIACAQAIDRWAEVFRGRWKEKGVDFGATRIGVHAGPALVGNFGGSRFFDYTAYGDTI 300 RA+ACA +D WAE F RWK +GV+FGATRIG HAGPALVGNFGG+RFFDYTAYGD+I Sbjct: 240 TRAVACAHDLDAWAEDFSARWKARGVNFGATRIGAHAGPALVGNFGGNRFFDYTAYGDSI 299 Query: 301 NTAARLETANKTLGTRVCVSAAVAHAAADFKGRPVGDLLLRGRSEPLRAYEPLAPAEFEA 360 N AARLE ANK LGTR+CVSA++A AA+F GRPVGDL+LRGRSEPLRA+EPLA A+FE+ Sbjct: 300 NIAARLEAANKHLGTRICVSASIAEGAANFHGRPVGDLMLRGRSEPLRAFEPLATAKFES 359 Query: 361 PATAQYARAFAKLEAEDTSAMPAFAALVGVHADDPLAGFHLKRLLNGGRGARMQL 415 AT +Y+ AFAK+EA D +AMPAFAALVG+HADD LAGFHL+RLLNG +G RMQL Sbjct: 360 AATTRYSEAFAKMEAGDAAAMPAFAALVGMHADDALAGFHLRRLLNGAKGIRMQL 414 >ref|YP_001772050.1| adenylate/guanylate cyclase [Methylobacterium sp. 4-46] gb|ACA19616.1| adenylate/guanylate cyclase [Methylobacterium sp. 4-46] Length = 421 Score = 571 bits (1471), Expect = e-160, Method: Compositional matrix adjust. Identities = 288/414 (69%), Positives = 334/414 (80%) Query: 3 ATILVVDDEPDLEALVLQKFRRQIRDGQVSFVFAHDGLEALQSIEAHPDVDLVVSDINMP 62 A ILVVDDEPDLEAL+LQ FRR+IR+G V F+FA DG+EAL + H DVDLVVSDINMP Sbjct: 6 AKILVVDDEPDLEALILQTFRRRIREGTVRFLFARDGVEALDLLTEHRDVDLVVSDINMP 65 Query: 63 RMDGLSLLAKLQEAEEKKSTIIVSAYGDMSNIRTAMNRGAFDFLTKPIDFADLETTIQKT 122 RMDGLSLLAKLQEA+EK ST+IVSAYGDM+NIR AMNRGAFDFLTKPIDFAD ETT+ +T Sbjct: 66 RMDGLSLLAKLQEADEKLSTVIVSAYGDMANIRVAMNRGAFDFLTKPIDFADFETTVDRT 125 Query: 123 IRHIDMLREARRRQVEAERAHASLSRYFSPELAKRLATGGDGNDMQVHWRDVAVIFTDIT 182 + H+ LREARRRQ EAERAHA+LSRYFSP LA+RLA H RDVA +FTD+ Sbjct: 126 VLHVRALREARRRQAEAERAHATLSRYFSPNLAERLAADASSLAAGGHRRDVASLFTDVA 185 Query: 183 GFTSLVETAAPEVLAELLNEYVGGLTDVVFAHEGTVAKVIGDAIQVLFNAPGEQADYANR 242 GFT+LVE+ P ++AELLN Y+ +T +VF +EGTVAK++GDAI VLF APGEQ D+A+R Sbjct: 186 GFTTLVESLDPALMAELLNGYLATMTGLVFRYEGTVAKIVGDAIHVLFGAPGEQPDHASR 245 Query: 243 AIACAQAIDRWAEVFRGRWKEKGVDFGATRIGVHAGPALVGNFGGSRFFDYTAYGDTINT 302 A+ACA A+D A+ R W E+GV GATRIGVHAGPA+VGNFGG RFFDYTAYGDTIN Sbjct: 246 AVACALALDEAAQALRAAWAERGVSLGATRIGVHAGPAIVGNFGGDRFFDYTAYGDTINI 305 Query: 303 AARLETANKTLGTRVCVSAAVAHAAADFKGRPVGDLLLRGRSEPLRAYEPLAPAEFEAPA 362 AARLE ANK LGTR+CVSAAVA A F+GRP+GDLLLRG+S PLRAYEPL+ A + PA Sbjct: 306 AARLEAANKVLGTRICVSAAVAERAEAFRGRPIGDLLLRGKSAPLRAYEPLSEAAYADPA 365 Query: 363 TAQYARAFAKLEAEDTSAMPAFAALVGVHADDPLAGFHLKRLLNGGRGARMQLG 416 TA+YA+AFAKL A+D A AFAAL+G DD LA FHL+RLLNG G R+ LG Sbjct: 366 TARYAQAFAKLAAQDPCATQAFAALIGQRPDDRLASFHLRRLLNGETGTRIDLG 419 >ref|YP_001769663.1| adenylate/guanylate cyclase [Methylobacterium sp. 4-46] gb|ACA17229.1| adenylate/guanylate cyclase [Methylobacterium sp. 4-46] Length = 447 Score = 570 bits (1468), Expect = e-160, Method: Compositional matrix adjust. Identities = 285/412 (69%), Positives = 336/412 (81%), Gaps = 3/412 (0%) Query: 5 ILVVDDEPDLEALVLQKFRRQIRDGQVSFVFAHDGLEALQSIEAHPDVDLVVSDINMPRM 64 +LVVDDE DLEAL++QKFRR+IR+G + F+FA DGLEAL I HPDVDLVVSDINMPRM Sbjct: 35 VLVVDDESDLEALIVQKFRRRIREGAIRFLFARDGLEALAVIAEHPDVDLVVSDINMPRM 94 Query: 65 DGLSLLAKLQEAEEKKSTIIVSAYGDMSNIRTAMNRGAFDFLTKPIDFADLETTIQKTIR 124 DGL+LLAKLQEA+EK ST+IVSAYGDM+NIRTAMNRGAFDFLTKPIDF+D ETT+ +T+ Sbjct: 95 DGLTLLAKLQEADEKLSTVIVSAYGDMANIRTAMNRGAFDFLTKPIDFSDFETTVDRTVL 154 Query: 125 HIDMLREARRRQVEAERAHASLSRYFSPELAKRLATGGDGNDMQV-HWRDVAVIFTDITG 183 H+ LREARRRQ AERAHASLSRYFSP LA+RLA D + + H RDVA +FTDI G Sbjct: 155 HVRTLREARRRQSAAERAHASLSRYFSPNLAERLA--ADASALAGGHRRDVASLFTDIAG 212 Query: 184 FTSLVETAAPEVLAELLNEYVGGLTDVVFAHEGTVAKVIGDAIQVLFNAPGEQADYANRA 243 FT+LVE+ P +LAELLN Y+ +T +VF+H+GTVAK++GDAI VLF APGEQ D+A RA Sbjct: 213 FTTLVESLDPALLAELLNGYLAEMTGLVFSHDGTVAKIVGDAIHVLFGAPGEQPDHATRA 272 Query: 244 IACAQAIDRWAEVFRGRWKEKGVDFGATRIGVHAGPALVGNFGGSRFFDYTAYGDTINTA 303 ++CA A+D AE FR RW E+GV G+TRIGVHAGPA+VGNFGG RFFDYTAYGDTIN Sbjct: 273 VSCALALDAAAEAFRARWAERGVVLGSTRIGVHAGPAIVGNFGGGRFFDYTAYGDTINIT 332 Query: 304 ARLETANKTLGTRVCVSAAVAHAAADFKGRPVGDLLLRGRSEPLRAYEPLAPAEFEAPAT 363 ARLE ANK LGTR+CVSAAVA A F+GRP+GDL+LRGR+E LR +EPL+ A F P T Sbjct: 333 ARLEAANKVLGTRLCVSAAVAERAEGFRGRPIGDLVLRGRTEALRTFEPLSEAAFADPGT 392 Query: 364 AQYARAFAKLEAEDTSAMPAFAALVGVHADDPLAGFHLKRLLNGGRGARMQL 415 A+Y AF KL A D A+PAFA+LVG++ADD LA FHL+RLLNG G R+ L Sbjct: 393 ARYGEAFEKLAAGDPGALPAFASLVGLNADDHLASFHLRRLLNGVSGTRIDL 444 >ref|YP_001758285.1| adenylate/guanylate cyclase [Methylobacterium radiotolerans JCM 2831] gb|ACB27602.1| adenylate/guanylate cyclase [Methylobacterium radiotolerans JCM 2831] Length = 421 Score = 553 bits (1425), Expect = e-155, Method: Compositional matrix adjust. Identities = 283/414 (68%), Positives = 333/414 (80%) Query: 2 TATILVVDDEPDLEALVLQKFRRQIRDGQVSFVFAHDGLEALQSIEAHPDVDLVVSDINM 61 A ILVVDDEPDLEAL+ QKFRRQIR G V+F+FAHDG EAL + DVDLVVSDINM Sbjct: 7 NAKILVVDDEPDLEALITQKFRRQIRQGLVTFLFAHDGQEALDRLSESRDVDLVVSDINM 66 Query: 62 PRMDGLSLLAKLQEAEEKKSTIIVSAYGDMSNIRTAMNRGAFDFLTKPIDFADLETTIQK 121 PRMDGL+LLAKLQ+ E+ S IIVSAYGDM+NIRTAMNRGAFDFLTKPIDFADLETTI++ Sbjct: 67 PRMDGLTLLAKLQDLPERPSIIIVSAYGDMANIRTAMNRGAFDFLTKPIDFADLETTIER 126 Query: 122 TIRHIDMLREARRRQVEAERAHASLSRYFSPELAKRLATGGDGNDMQVHWRDVAVIFTDI 181 T+RH++ LRE RRRQ AERAHASL+RYFSP LA+RLA G ++ H RDVA +FTDI Sbjct: 127 TLRHVEDLREGRRRQSLAERAHASLARYFSPNLAERLAGDASGLELGGHRRDVASLFTDI 186 Query: 182 TGFTSLVETAAPEVLAELLNEYVGGLTDVVFAHEGTVAKVIGDAIQVLFNAPGEQADYAN 241 GFTSLVE+ P LAE+LN Y +TDVVFAHEGTVAK++GDA+ VLF APG+Q D+A Sbjct: 187 AGFTSLVESLDPVQLAEILNGYFAEMTDVVFAHEGTVAKIVGDALHVLFGAPGDQPDHAA 246 Query: 242 RAIACAQAIDRWAEVFRGRWKEKGVDFGATRIGVHAGPALVGNFGGSRFFDYTAYGDTIN 301 RA+ACA A+D AE FRGRW+E+G++ G TRIGVHAGPA+VGNFGG R+FDYTAYGDTIN Sbjct: 247 RAVACALALDEAAEAFRGRWRERGIEIGVTRIGVHAGPAIVGNFGGGRYFDYTAYGDTIN 306 Query: 302 TAARLETANKTLGTRVCVSAAVAHAAADFKGRPVGDLLLRGRSEPLRAYEPLAPAEFEAP 361 TAARLE ANK GTR+CVS AV A F+GRP+GDLLLRG+ LRAYEPL A + Sbjct: 307 TAARLENANKAFGTRICVSDAVVIRAGQFRGRPLGDLLLRGKQTALRAYEPLTEAAYADA 366 Query: 362 ATAQYARAFAKLEAEDTSAMPAFAALVGVHADDPLAGFHLKRLLNGGRGARMQL 415 AQY A+AKL+A + A+PAFAALVG+ DD +A +HLKRLLNG G+R+++ Sbjct: 367 LLAQYQDAYAKLDAGEAGALPAFAALVGLRPDDGVAAYHLKRLLNGSSGSRVEV 420 >ref|ZP_03502865.1| adenylate/guanylate cyclase [Rhizobium etli Kim 5] Length = 319 Score = 440 bits (1132), Expect = e-121, Method: Compositional matrix adjust. Identities = 211/319 (66%), Positives = 256/319 (80%) Query: 1 MTATILVVDDEPDLEALVLQKFRRQIRDGQVSFVFAHDGLEALQSIEAHPDVDLVVSDIN 60 M+ +ILVVDDEPDLE L++QKFRR IRDG + F+FA DG+EAL + H +VD+V+SDIN Sbjct: 1 MSISILVVDDEPDLEILLVQKFRRSIRDGALRFLFARDGVEALTILADHEEVDVVLSDIN 60 Query: 61 MPRMDGLSLLAKLQEAEEKKSTIIVSAYGDMSNIRTAMNRGAFDFLTKPIDFADLETTIQ 120 MPRMDGLSLLA+L+E E STIIVSAY DM+NIRTAMNRGA+DF+TKPIDF DLE TI Sbjct: 61 MPRMDGLSLLARLRERGETLSTIIVSAYSDMANIRTAMNRGAYDFVTKPIDFCDLEATID 120 Query: 121 KTIRHIDMLREARRRQVEAERAHASLSRYFSPELAKRLATGGDGNDMQVHWRDVAVIFTD 180 KTIRH++ +RE +RRQ AE+A ASLSRYFSP LA RLA+ + D+ R+V +FTD Sbjct: 121 KTIRHVENMREVQRRQALAEQARASLSRYFSPNLADRLASSANALDLGGARREVVSLFTD 180 Query: 181 ITGFTSLVETAAPEVLAELLNEYVGGLTDVVFAHEGTVAKVIGDAIQVLFNAPGEQADYA 240 +TGFTSLVE P VL LLN+Y+ G+TD+VFAHEGTVAK+IGDA+ VLF AP +Q D+A Sbjct: 181 LTGFTSLVEAIEPNVLGPLLNDYIVGMTDIVFAHEGTVAKIIGDALHVLFGAPADQPDHA 240 Query: 241 NRAIACAQAIDRWAEVFRGRWKEKGVDFGATRIGVHAGPALVGNFGGSRFFDYTAYGDTI 300 +RAIAC+ +D +A FR W +KG+ G TRIG HAG A+VGNFGG RFFDY+AYGDTI Sbjct: 241 DRAIACSLELDGFACSFREHWSKKGIPLGHTRIGAHAGSAVVGNFGGGRFFDYSAYGDTI 300 Query: 301 NTAARLETANKTLGTRVCV 319 N AARL+ ANKTLGTR+CV Sbjct: 301 NVAARLQAANKTLGTRICV 319