BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0212.0010.p (535 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_07027983.1| drug resistance transporter, EmrB/QacA subfam... 839 0.0 ref|YP_004142943.1| EmrB/QacA subfamily drug resistance transpor... 647 0.0 ref|YP_002495660.1| EmrB/QacA subfamily drug resistance transpor... 639 0.0 ref|YP_004611162.1| EmrB/QacA subfamily drug resistance transpor... 635 e-180 ref|YP_001923909.1| drug resistance transporter, EmrB/QacA subfa... 627 e-177 >ref|ZP_07027983.1| drug resistance transporter, EmrB/QacA subfamily [Afipia sp. 1NLS2] gb|EFI50804.1| drug resistance transporter, EmrB/QacA subfamily [Afipia sp. 1NLS2] Length = 537 Score = 839 bits (2168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/532 (77%), Positives = 468/532 (87%) Query: 4 VAAGGGAAWSPERSAAGGHNPYLIAFVVSIATFMEVLDTTIANVALRHIAGGLAVGIDES 63 V G WSPERSAAGGHNPYLIAFVVSIATFMEVLDTTIANV+LR+IAGGLAVGIDES Sbjct: 5 VHDGSAGGWSPERSAAGGHNPYLIAFVVSIATFMEVLDTTIANVSLRYIAGGLAVGIDES 64 Query: 64 TYVITSYLVANAIVLSISGWLSTVIGRKRFYMICVGTFAFASLLCGLAWSLEALVLFRII 123 TYVITSYLVANAIVLSISGWLSTVIGRKRFYM CV F ASLLCG AW+L++LVLFRI+ Sbjct: 65 TYVITSYLVANAIVLSISGWLSTVIGRKRFYMSCVAVFTLASLLCGFAWNLQSLVLFRIL 124 Query: 124 QGLGGGGMATSEQAILADSFPPAKRGQAFAIYGVAVVVAPVIGPTLGGWITDTYSWHWIF 183 QGLGGGGMATSEQAILADSFPPAKRGQAFAIYGVAVVVAP++GPTLGGWI+DTYSWHWIF Sbjct: 125 QGLGGGGMATSEQAILADSFPPAKRGQAFAIYGVAVVVAPIVGPTLGGWISDTYSWHWIF 184 Query: 184 LINVPMGLLSLFLVGMLVKEPSGAEQERKQLLKDGLRVDYIGFVLVAIGLGSLEFVLDEG 243 LINVPMGLLSLFLVG LVKEPSGAE ER +LL GLRVDY+GF LVA+GLGSLEFVLDEG Sbjct: 185 LINVPMGLLSLFLVGTLVKEPSGAETERVKLLSKGLRVDYVGFALVAVGLGSLEFVLDEG 244 Query: 244 QRKDWFGSNMIVGFAFASAICLIALVPWELTRKEPIVDLRLLGRRQFGSCFLVMLCTGAV 303 QR DWFGSNMIV FA SA CLI LV WEL +PI+D+RLLG+RQFG+CFL ML TGA+ Sbjct: 245 QRNDWFGSNMIVMFAVVSAACLIVLVSWELICDDPIIDIRLLGQRQFGTCFLAMLGTGAI 304 Query: 304 LISSTQLLPQLLQTELNYTALLAGLALSPGGIVTLILMPVVGHLVSRVQPKYLIAIGGCI 363 ++++TQ+LPQLLQTEL YTA+LAGL LSPGG+VTL +MPV G L+ VQ KYLIA G I Sbjct: 305 VVATTQILPQLLQTELGYTAMLAGLVLSPGGVVTLFMMPVTGRLIGLVQAKYLIAAGATI 364 Query: 364 VAFSMWHLTGLNGDITYGYAALARIFLSAGLPFLFLPVTTASYDGVPPDKTNQASALINV 423 A SMW+LTGLNG+ITY YAA++RI+L+ GLP LFLP+TTASY+G+PP+KTNQASALINV Sbjct: 365 AALSMWNLTGLNGNITYDYAAMSRIYLALGLPLLFLPITTASYEGLPPEKTNQASALINV 424 Query: 424 ARNIGGSMGVALAQTALAQRQQFHQSRLVEHAAPSDLGYQQTIDTMTRFFQAQGSNASDA 483 ARN+GGS+GVAL QT LAQRQQFHQSRL+EH PS++GYQQT+ +TRFFQAQGS+A+DA Sbjct: 425 ARNLGGSLGVALVQTLLAQRQQFHQSRLIEHIVPSNVGYQQTLSAVTRFFQAQGSSATDA 484 Query: 484 ASQAVAWVGQILQRQVDLLAYIDVFWMLSIIGLVMIPLALIIKPVDLTAPPK 535 A+QA ++ Q LQ QV+LLAYIDVFW L++IG +M PLAL ++ +D+ AP + Sbjct: 485 AAQAFGYIAQTLQTQVNLLAYIDVFWALALIGAIMAPLALTLRSIDMNAPAR 536 >ref|YP_004142943.1| EmrB/QacA subfamily drug resistance transporter [Mesorhizobium ciceri biovar biserrulae WSM1271] gb|ADV12893.1| drug resistance transporter, EmrB/QacA subfamily [Mesorhizobium ciceri biovar biserrulae WSM1271] Length = 526 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 312/496 (62%), Positives = 388/496 (78%) Query: 13 SPERSAAGGHNPYLIAFVVSIATFMEVLDTTIANVALRHIAGGLAVGIDESTYVITSYLV 72 S RSAAGG NP+LIA VVSIATFM VLDT+IANVALR+IAG LA G+DEST+VIT+YLV Sbjct: 6 SESRSAAGGRNPWLIAVVVSIATFMLVLDTSIANVALRNIAGSLAAGMDESTWVITTYLV 65 Query: 73 ANAIVLSISGWLSTVIGRKRFYMICVGTFAFASLLCGLAWSLEALVLFRIIQGLGGGGMA 132 AN++++ +SGWL++VIGRKR+YM+CV F ASLLCGLA +LE L++FRI+QGLGGGGMA Sbjct: 66 ANSVIIPVSGWLASVIGRKRYYMLCVAIFTIASLLCGLAPNLEMLIVFRILQGLGGGGMA 125 Query: 133 TSEQAILADSFPPAKRGQAFAIYGVAVVVAPVIGPTLGGWITDTYSWHWIFLINVPMGLL 192 SEQ+ILAD+FPP KR QAFA+YG+AV+VAP +GPT+GGW+TD +SWHWIF INVP G++ Sbjct: 126 PSEQSILADTFPPEKRSQAFALYGIAVIVAPTVGPTIGGWLTDHFSWHWIFFINVPFGIM 185 Query: 193 SLFLVGMLVKEPSGAEQERKQLLKDGLRVDYIGFVLVAIGLGSLEFVLDEGQRKDWFGSN 252 SL LV LV EP E+ER++ LK GLR+D++GF+LVA LG LE LDEGQR DWF S Sbjct: 186 SLALVQWLVVEPDVLERERQERLKGGLRIDWVGFILVATALGCLEIFLDEGQRNDWFASG 245 Query: 253 MIVGFAFASAICLIALVPWELTRKEPIVDLRLLGRRQFGSCFLVMLCTGAVLISSTQLLP 312 IV FA SA+ + L+PWE + ++PIVD+RLL RQFG+ FLVM+ GAVL S+TQL+P Sbjct: 246 FIVTFAAISAVSFLLLIPWEFSHRDPIVDVRLLFSRQFGTSFLVMMAVGAVLFSTTQLMP 305 Query: 313 QLLQTELNYTALLAGLALSPGGIVTLILMPVVGHLVSRVQPKYLIAIGGCIVAFSMWHLT 372 QL QT NYTA L+GL++ PGGI L+LMPV G + VQPKYLI G +VA ++WH+T Sbjct: 306 QLQQTAFNYTATLSGLSMMPGGIAMLMLMPVSGFAGAIVQPKYLIMAGMSVVAVALWHMT 365 Query: 373 GLNGDITYGYAALARIFLSAGLPFLFLPVTTASYDGVPPDKTNQASALINVARNIGGSMG 432 L D+++G+ A ARIFL GLPFLF+P++TA+Y G+ P +TNQASALINVARNIGGS+G Sbjct: 366 SLTPDVSFGFFAFARIFLMIGLPFLFIPISTAAYVGLAPQQTNQASALINVARNIGGSIG 425 Query: 433 VALAQTALAQRQQFHQSRLVEHAAPSDLGYQQTIDTMTRFFQAQGSNASDAASQAVAWVG 492 V+L+ T +AQ Q HQ+ LV H A S YQQ + T F AQGS DA QAV W+G Sbjct: 426 VSLSNTVIAQNAQIHQANLVGHTAQSSPAYQQVLRQATEHFVAQGSPMIDAKQQAVGWIG 485 Query: 493 QILQRQVDLLAYIDVF 508 Q++ RQ LLAYIDVF Sbjct: 486 QLIARQASLLAYIDVF 501 >ref|YP_002495660.1| EmrB/QacA subfamily drug resistance transporter [Methylobacterium nodulans ORS 2060] gb|ACL55357.1| drug resistance transporter, EmrB/QacA subfamily [Methylobacterium nodulans ORS 2060] Length = 531 Score = 639 bits (1649), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/517 (61%), Positives = 406/517 (78%) Query: 13 SPERSAAGGHNPYLIAFVVSIATFMEVLDTTIANVALRHIAGGLAVGIDESTYVITSYLV 72 P SAAGGHNP+L+A VV+IATFMEVLDTTIANVALR+I+GGLAVG DE+ +V+TSYLV Sbjct: 5 DPADSAAGGHNPWLVAVVVAIATFMEVLDTTIANVALRYISGGLAVGPDEAAWVVTSYLV 64 Query: 73 ANAIVLSISGWLSTVIGRKRFYMICVGTFAFASLLCGLAWSLEALVLFRIIQGLGGGGMA 132 ANAIVL+ S +++ GRK F+M + F +S+LCG AWSLE+L++FR++QGLGGGGMA Sbjct: 65 ANAIVLTASSFVAKRYGRKAFFMAAIALFTVSSILCGFAWSLESLLVFRVLQGLGGGGMA 124 Query: 133 TSEQAILADSFPPAKRGQAFAIYGVAVVVAPVIGPTLGGWITDTYSWHWIFLINVPMGLL 192 Q+ILADSFPP KRGQAFA+YG+A+VVAPV+GPTLGGW++DTYSWHW FLIN P+G++ Sbjct: 125 PLAQSILADSFPPEKRGQAFALYGIAIVVAPVVGPTLGGWLSDTYSWHWCFLINAPVGVI 184 Query: 193 SLFLVGMLVKEPSGAEQERKQLLKDGLRVDYIGFVLVAIGLGSLEFVLDEGQRKDWFGSN 252 +L L+ +LV++P A +ER++L ++G+ D +GFVLVA LGSLE VLD+GQRKDWFGSN Sbjct: 185 ALGLIHLLVQDPKSAIEERERLRREGVDFDLVGFVLVATFLGSLEVVLDQGQRKDWFGSN 244 Query: 253 MIVGFAFASAICLIALVPWELTRKEPIVDLRLLGRRQFGSCFLVMLCTGAVLISSTQLLP 312 +IV FA I A++PWELTR+ P+VDLRLLGRRQFGSCFLVM+ TGA+LI++TQ LP Sbjct: 245 LIVTFAVFMGIAFAAIIPWELTRRNPVVDLRLLGRRQFGSCFLVMMATGAILIATTQFLP 304 Query: 313 QLLQTELNYTALLAGLALSPGGIVTLILMPVVGHLVSRVQPKYLIAIGGCIVAFSMWHLT 372 QLLQ YTA AGLALSPGG+VT ++M V+G + S VQPKYLIA G I+A +M LT Sbjct: 305 QLLQDHFGYTATWAGLALSPGGLVTCLMMFVIGRIASVVQPKYLIAGGAAIIAVAMVDLT 364 Query: 373 GLNGDITYGYAALARIFLSAGLPFLFLPVTTASYDGVPPDKTNQASALINVARNIGGSMG 432 L GD+ +G+ +RI + GLP +FL +T ASY+G+ P +T+QASALINVARN+GGSMG Sbjct: 365 NLYGDLDFGFFVWSRIAIGIGLPMIFLSITAASYEGIAPAQTDQASALINVARNVGGSMG 424 Query: 433 VALAQTALAQRQQFHQSRLVEHAAPSDLGYQQTIDTMTRFFQAQGSNASDAASQAVAWVG 492 V+LAQ LA RQQFH SRLVEH PS+ YQ+T+ T +F G++ DA SQA AW+G Sbjct: 425 VSLAQNMLAYRQQFHTSRLVEHVVPSEPAYQETLRHATDYFATHGASTVDAQSQAFAWIG 484 Query: 493 QILQRQVDLLAYIDVFWMLSIIGLVMIPLALIIKPVD 529 Q +Q Q LAYIDVFW L+++ IPLA+I+ V Sbjct: 485 QQVQTQSAFLAYIDVFWTLAMVSAATIPLAMILTSVK 521 >ref|YP_004611162.1| EmrB/QacA subfamily drug resistance transporter [Mesorhizobium opportunistum WSM2075] gb|AEH87068.1| drug resistance transporter, EmrB/QacA subfamily [Mesorhizobium opportunistum WSM2075] Length = 528 Score = 635 bits (1639), Expect = e-180, Method: Compositional matrix adjust. Identities = 313/516 (60%), Positives = 396/516 (76%) Query: 11 AWSPERSAAGGHNPYLIAFVVSIATFMEVLDTTIANVALRHIAGGLAVGIDESTYVITSY 70 A S RSAAGG NP+LIA VVSIATFM VLDT+IANVALR+IAG LA G+DEST+VIT+Y Sbjct: 4 AQSESRSAAGGRNPWLIAIVVSIATFMLVLDTSIANVALRNIAGSLAAGMDESTWVITTY 63 Query: 71 LVANAIVLSISGWLSTVIGRKRFYMICVGTFAFASLLCGLAWSLEALVLFRIIQGLGGGG 130 LVAN++++ +SGWL++VIGRKR+YM+CV TF ASLLCGLA +LE L++FRI+QGLGGGG Sbjct: 64 LVANSVIIPVSGWLASVIGRKRYYMLCVATFTIASLLCGLAPNLELLIVFRILQGLGGGG 123 Query: 131 MATSEQAILADSFPPAKRGQAFAIYGVAVVVAPVIGPTLGGWITDTYSWHWIFLINVPMG 190 MA SEQ+ILAD+FPP KR QAFA+YG+AV+VAP +GPT+GGW+TD +SWHWIF INVP G Sbjct: 124 MAPSEQSILADTFPPEKRSQAFALYGIAVIVAPTVGPTIGGWLTDHFSWHWIFFINVPFG 183 Query: 191 LLSLFLVGMLVKEPSGAEQERKQLLKDGLRVDYIGFVLVAIGLGSLEFVLDEGQRKDWFG 250 ++SL LV LV EP E+ER + LK GLR+D++GFVLVA LG LE LDEGQR DWF Sbjct: 184 IMSLALVQWLVVEPDVLERERLERLKGGLRIDWVGFVLVATALGCLEIFLDEGQRNDWFA 243 Query: 251 SNMIVGFAFASAICLIALVPWELTRKEPIVDLRLLGRRQFGSCFLVMLCTGAVLISSTQL 310 S I FA SAI + L+PWE ++P+VD+RLL RQFG+ FLVM+ GAVL S+TQL Sbjct: 244 SAFITTFAVISAISFLLLIPWEFNHRDPVVDIRLLFSRQFGTSFLVMMAVGAVLFSTTQL 303 Query: 311 LPQLLQTELNYTALLAGLALSPGGIVTLILMPVVGHLVSRVQPKYLIAIGGCIVAFSMWH 370 +PQL QT +YTA L+GL++ PGGI LILMP+ G S VQPKYLI G VA ++WH Sbjct: 304 MPQLQQTAFDYTATLSGLSMMPGGIAMLILMPISGFAGSIVQPKYLIMAGMSAVAIALWH 363 Query: 371 LTGLNGDITYGYAALARIFLSAGLPFLFLPVTTASYDGVPPDKTNQASALINVARNIGGS 430 +T L D ++ + A AR+FL GLPFLF+P++TA+Y G+ P +TNQASALINVARNIGGS Sbjct: 364 MTALTPDASFRFFAFARVFLMIGLPFLFIPISTAAYVGLAPQQTNQASALINVARNIGGS 423 Query: 431 MGVALAQTALAQRQQFHQSRLVEHAAPSDLGYQQTIDTMTRFFQAQGSNASDAASQAVAW 490 +GV+L+ T +AQ Q HQ+ LV H A S YQQ + T F AQGS +A QA+ W Sbjct: 424 IGVSLSNTVIAQNAQLHQAHLVGHTAQSSPAYQQVLRQATEHFVAQGSPMVEAKQQAIGW 483 Query: 491 VGQILQRQVDLLAYIDVFWMLSIIGLVMIPLALIIK 526 +GQ++ RQ LLAY+DVF ++ +++PLAL+++ Sbjct: 484 IGQLIARQASLLAYVDVFRYCAVATAILVPLALLLR 519 >ref|YP_001923909.1| drug resistance transporter, EmrB/QacA subfamily [Methylobacterium populi BJ001] gb|ACB79374.1| drug resistance transporter, EmrB/QacA subfamily [Methylobacterium populi BJ001] Length = 536 Score = 627 bits (1618), Expect = e-177, Method: Compositional matrix adjust. Identities = 308/517 (59%), Positives = 397/517 (76%), Gaps = 1/517 (0%) Query: 15 ERSAAGGHNPYLIAFVVSIATFMEVLDTTIANVALRHIAGGLAVGIDESTYVITSYLVAN 74 + A GGHNP+++A VV++ATFMEVLDTTIANVALR+I+G LAVG DES +V+TSYLVAN Sbjct: 12 QAKAPGGHNPWIVALVVALATFMEVLDTTIANVALRYISGALAVGPDESAWVVTSYLVAN 71 Query: 75 AIVLSISGWLSTVIGRKRFYMICVGTFAFASLLCGLAWSLEALVLFRIIQGLGGGGMATS 134 AI L S +L+ GRK F+M V F +S+LCG AWSLE+L+ FR++QGLGGGGMA Sbjct: 72 AITLIASSFLAKRYGRKAFFMWSVALFTLSSVLCGFAWSLESLLFFRVLQGLGGGGMAPL 131 Query: 135 EQAILADSFPPAKRGQAFAIYGVAVVVAPVIGPTLGGWITDTYSWHWIFLINVPMGLLSL 194 Q+ILADSFPP KRGQAFA+YGVA+VVAPVIGPTLGGW++D SWHW FLIN P+G+++L Sbjct: 132 AQSILADSFPPEKRGQAFALYGVAIVVAPVIGPTLGGWLSDNASWHWCFLINGPVGVIAL 191 Query: 195 FLVGMLVKEPSGAEQERKQLLKDGLRVDYIGFVLVAIGLGSLEFVLDEGQRKDWFGSNMI 254 L+ L+++ A++ER+ L + G+R D +GF+LVA LGSLE +LDEGQRKDWFG++ + Sbjct: 192 ALMYWLIEDSEAAKRERRALREKGIRFDLVGFLLVATFLGSLEVILDEGQRKDWFGTSTL 251 Query: 255 VG-FAFASAICLIALVPWELTRKEPIVDLRLLGRRQFGSCFLVMLCTGAVLISSTQLLPQ 313 + F + + +A++PW LT K P++DLRLL RRQF +CF+VML TGAVLIS+TQ +PQ Sbjct: 252 MNVFGVLTVVSFLAMMPWLLTAKNPVIDLRLLKRRQFSACFVVMLFTGAVLISTTQFIPQ 311 Query: 314 LLQTELNYTALLAGLALSPGGIVTLILMPVVGHLVSRVQPKYLIAIGGCIVAFSMWHLTG 373 + Q YTA L+GL L PGGI+T++ M VVG + S +QPK+LIA GG IVA ++ LT Sbjct: 312 ITQEYYGYTATLSGLVLGPGGIMTVVSMLVVGRVSSFIQPKWLIAAGGTIVALGLYDLTR 371 Query: 374 LNGDITYGYAALARIFLSAGLPFLFLPVTTASYDGVPPDKTNQASALINVARNIGGSMGV 433 L GD T+G+ A +RI++ GLP +FL VT+ASY+G+P DKT+QASALINVARN+GGSMGV Sbjct: 372 LYGDTTFGFFAWSRIYIGIGLPMIFLSVTSASYEGLPKDKTDQASALINVARNVGGSMGV 431 Query: 434 ALAQTALAQRQQFHQSRLVEHAAPSDLGYQQTIDTMTRFFQAQGSNASDAASQAVAWVGQ 493 +LAQ LA R QFHQSRLV+ PS YQQT+ TR+FQ G DA +QAVAW+GQ Sbjct: 432 SLAQNVLAYRSQFHQSRLVDTLDPSSPAYQQTLSQATRYFQQHGFAGPDAQNQAVAWIGQ 491 Query: 494 ILQRQVDLLAYIDVFWMLSIIGLVMIPLALIIKPVDL 530 L QV AYIDVFW+L+++ ++PLALI+K V L Sbjct: 492 QLATQVAYWAYIDVFWVLAVLTAGLVPLALILKTVKL 528