BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0206.0014.p (295 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001205173.1| putative 3-hydroxyisobutyrate dehydrogenase ... 484 e-135 ref|YP_577798.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter... 462 e-128 ref|ZP_01046632.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobact... 453 e-125 ref|YP_318762.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter... 444 e-122 ref|YP_001239577.1| 3-hydroxyisobutyrate dehydrogenase [Bradyrhi... 441 e-122 >ref|YP_001205173.1| putative 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobium sp. ORS 278] emb|CAL76938.1| putative 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobium sp. ORS 278] Length = 296 Score = 484 bits (1247), Expect = e-135, Method: Compositional matrix adjust. Identities = 249/293 (84%), Positives = 268/293 (91%) Query: 1 MANVAFIGLGNMGGPMAANLIKAGHKVTAFDLVAASRDQAKSDGAAIAESGVGAVKGADV 60 MA +AFIGLGNMGGPMAANL+KAGH+V AFDLV ASR QAK+DGAAIAES V AVKGAD Sbjct: 1 MATIAFIGLGNMGGPMAANLVKAGHQVVAFDLVEASRAQAKADGAAIAESAVVAVKGADA 60 Query: 61 VITMLPAGKHVLGVWNEVLPAMAKGALIIDCSTIDVESAKQAHALAAKHGMASVDAPVSG 120 V+TMLPAGKHVL VWNEV+PAM+KGALIID STIDVESA+ AHALAAKHG+A+VDAPVSG Sbjct: 61 VVTMLPAGKHVLAVWNEVVPAMSKGALIIDSSTIDVESARSAHALAAKHGIAAVDAPVSG 120 Query: 121 GTGGAKGATLTFMCGGEPKAFAAAQPMLANMGKKIVHCGAGGAGQAAKICNNMILGISMI 180 GTGGAK ATLTFMCGGE AFAAA+P+L MGKKIVHCG GAGQAAKICNNMILGISMI Sbjct: 121 GTGGAKAATLTFMCGGEEGAFAAAKPILETMGKKIVHCGGAGAGQAAKICNNMILGISMI 180 Query: 181 AVGEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTYCPVPGPVPTSPANNDYKPGFASNL 240 AVGEAF L EKLGLSHQALFDVASTSSGQCWSLT+YCPVPGPVP SPANNDY+PGFA+ L Sbjct: 181 AVGEAFALGEKLGLSHQALFDVASTSSGQCWSLTSYCPVPGPVPASPANNDYRPGFATAL 240 Query: 241 MVKDLTLAQDAANAAGAVTPLGKHAQEIYKTFDASGHGGVDFSGIIQHVRALA 293 M+KDLTL+QDAA AAGA TPLG+HAQEIYK FDA+GHGGVDFSGIIQHVR LA Sbjct: 241 MLKDLTLSQDAAKAAGAATPLGQHAQEIYKAFDAAGHGGVDFSGIIQHVRKLA 293 >ref|YP_577798.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter hamburgensis X14] gb|ABE63338.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter hamburgensis X14] Length = 299 Score = 462 bits (1188), Expect = e-128, Method: Compositional matrix adjust. Identities = 224/293 (76%), Positives = 253/293 (86%) Query: 1 MANVAFIGLGNMGGPMAANLIKAGHKVTAFDLVAASRDQAKSDGAAIAESGVGAVKGADV 60 MA +AFIGLGNMGGPMAANL KAGHKV FDLV A R AK+DG IA+ AV ADV Sbjct: 1 MATIAFIGLGNMGGPMAANLAKAGHKVNGFDLVPALRGAAKADGVTIADGARAAVTNADV 60 Query: 61 VITMLPAGKHVLGVWNEVLPAMAKGALIIDCSTIDVESAKQAHALAAKHGMASVDAPVSG 120 +ITMLPAG+HV+ VW +V+P +GAL+IDCSTIDVESA++AH LAA+ + SVDAPVSG Sbjct: 61 IITMLPAGRHVVSVWTDVIPCAVRGALMIDCSTIDVESARRAHMLAARAVLLSVDAPVSG 120 Query: 121 GTGGAKGATLTFMCGGEPKAFAAAQPMLANMGKKIVHCGAGGAGQAAKICNNMILGISMI 180 G GGA+GATLTFM GGE +AF AA+P L MGKKIVHCG GAGQAAKICNNMILGISMI Sbjct: 121 GVGGARGATLTFMAGGEAEAFVAAKPFLEAMGKKIVHCGGDGAGQAAKICNNMILGISMI 180 Query: 181 AVGEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTYCPVPGPVPTSPANNDYKPGFASNL 240 AVGEAFVLAEKLGLSHQALFDVAST+SGQCWSLT+YCPVPGPVP SPANNDYKPGFAS L Sbjct: 181 AVGEAFVLAEKLGLSHQALFDVASTASGQCWSLTSYCPVPGPVPASPANNDYKPGFASAL 240 Query: 241 MVKDLTLAQDAANAAGAVTPLGKHAQEIYKTFDASGHGGVDFSGIIQHVRALA 293 M+KDLTLAQ+AA + GA TPLG+HAQ+IYK FDA+G+GGVDFSG+I+H+RALA Sbjct: 241 MLKDLTLAQEAAKSTGAATPLGQHAQDIYKAFDAAGNGGVDFSGVIRHIRALA 293 >ref|ZP_01046632.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter sp. Nb-311A] gb|EAQ35468.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter sp. Nb-311A] Length = 298 Score = 453 bits (1165), Expect = e-125, Method: Compositional matrix adjust. Identities = 217/293 (74%), Positives = 251/293 (85%) Query: 1 MANVAFIGLGNMGGPMAANLIKAGHKVTAFDLVAASRDQAKSDGAAIAESGVGAVKGADV 60 MA +AFIGLGNMGGPMAANL+KA H+V FDLV SRD AK++G IA S AV ADV Sbjct: 1 MAAIAFIGLGNMGGPMAANLVKADHRVVGFDLVPESRDAAKTNGVTIAGSARAAVTNADV 60 Query: 61 VITMLPAGKHVLGVWNEVLPAMAKGALIIDCSTIDVESAKQAHALAAKHGMASVDAPVSG 120 +ITMLPAG+HV+ VW +V+PA +GAL+IDCSTIDVESA++AH LAA+ + SVDAPVSG Sbjct: 61 IITMLPAGRHVVSVWTDVMPAATRGALMIDCSTIDVESARRAHMLAARASLHSVDAPVSG 120 Query: 121 GTGGAKGATLTFMCGGEPKAFAAAQPMLANMGKKIVHCGAGGAGQAAKICNNMILGISMI 180 G GA+ ATLTFM GGE ++F AA+P L MGKKI+HCG G GQAAKICNNMILG+SMI Sbjct: 121 GVVGARDATLTFMAGGEVESFEAAKPFLEAMGKKIIHCGRDGTGQAAKICNNMILGVSMI 180 Query: 181 AVGEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTYCPVPGPVPTSPANNDYKPGFASNL 240 AVGEAFVLAEKLGLSHQALFD AS +SGQCWSLT+YCPVPGPVPTSPAN+ YKPGF S L Sbjct: 181 AVGEAFVLAEKLGLSHQALFDAASNASGQCWSLTSYCPVPGPVPTSPANSGYKPGFVSAL 240 Query: 241 MVKDLTLAQDAANAAGAVTPLGKHAQEIYKTFDASGHGGVDFSGIIQHVRALA 293 M+KDLTLAQ+AA ++GAVTPLG+HAQ+IYK FDA+G+GGVDFSGIIQH+RALA Sbjct: 241 MLKDLTLAQEAAKSSGAVTPLGQHAQDIYKAFDAAGNGGVDFSGIIQHIRALA 293 >ref|YP_318762.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter winogradskyi Nb-255] gb|ABA05410.1| 3-hydroxyisobutyrate dehydrogenase [Nitrobacter winogradskyi Nb-255] Length = 299 Score = 444 bits (1141), Expect = e-122, Method: Compositional matrix adjust. Identities = 213/293 (72%), Positives = 247/293 (84%) Query: 1 MANVAFIGLGNMGGPMAANLIKAGHKVTAFDLVAASRDQAKSDGAAIAESGVGAVKGADV 60 MA +AFIGLGNMGGPMAANL+KAGH V FDLV A D A+++G IA S AV ADV Sbjct: 1 MAAIAFIGLGNMGGPMAANLVKAGHSVVGFDLVPALCDAARTNGVTIAGSARAAVTNADV 60 Query: 61 VITMLPAGKHVLGVWNEVLPAMAKGALIIDCSTIDVESAKQAHALAAKHGMASVDAPVSG 120 +ITMLPAG+HV+ VW +V+PA +GAL+IDCSTIDVESA++AH LAA+ + SVDAPVSG Sbjct: 61 IITMLPAGRHVVSVWTDVMPAATRGALMIDCSTIDVESARRAHMLAARASLHSVDAPVSG 120 Query: 121 GTGGAKGATLTFMCGGEPKAFAAAQPMLANMGKKIVHCGAGGAGQAAKICNNMILGISMI 180 G GA+ ATLTFM GGE ++F A+P L MGKKIVHCG G GQAAKICNNMILG+SMI Sbjct: 121 GVAGARDATLTFMVGGEVESFEDAKPFLEAMGKKIVHCGRDGTGQAAKICNNMILGVSMI 180 Query: 181 AVGEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTYCPVPGPVPTSPANNDYKPGFASNL 240 AV EAFVLAEKLGLSHQALFD AS +SGQCWSLT+YCPVPGPVPTSPANNDY+PGFAS L Sbjct: 181 AVAEAFVLAEKLGLSHQALFDAASKASGQCWSLTSYCPVPGPVPTSPANNDYRPGFASAL 240 Query: 241 MVKDLTLAQDAANAAGAVTPLGKHAQEIYKTFDASGHGGVDFSGIIQHVRALA 293 M+KDLTLA+ AA++ G VTPLG+HAQ+IYK FDA+G+G VDFSGII+H+RALA Sbjct: 241 MLKDLTLARAAADSTGTVTPLGQHAQDIYKAFDAAGNGEVDFSGIIRHIRALA 293 >ref|YP_001239577.1| 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobium sp. BTAi1] gb|ABQ35671.1| 3-hydroxyisobutyrate dehydrogenase [Bradyrhizobium sp. BTAi1] Length = 296 Score = 441 bits (1134), Expect = e-122, Method: Compositional matrix adjust. Identities = 245/293 (83%), Positives = 264/293 (90%) Query: 1 MANVAFIGLGNMGGPMAANLIKAGHKVTAFDLVAASRDQAKSDGAAIAESGVGAVKGADV 60 MA +AFIGLGNMGGPMAANL+KAGHKV AFDLV ASR QAK+DGA IA S + A KGAD Sbjct: 1 MATIAFIGLGNMGGPMAANLVKAGHKVVAFDLVEASRAQAKTDGAEIAASALAAAKGADA 60 Query: 61 VITMLPAGKHVLGVWNEVLPAMAKGALIIDCSTIDVESAKQAHALAAKHGMASVDAPVSG 120 V+TMLPAGKHVL VWNEV+PAMAKGALIID STIDVESA+ AHALAAKHG+A++DAPVSG Sbjct: 61 VVTMLPAGKHVLAVWNEVVPAMAKGALIIDSSTIDVESARAAHALAAKHGIAAIDAPVSG 120 Query: 121 GTGGAKGATLTFMCGGEPKAFAAAQPMLANMGKKIVHCGAGGAGQAAKICNNMILGISMI 180 GTGGAK ATLTFMCGGE AFAAA+P+L MGKKIVHCG GAGQAAKICNNMILGISMI Sbjct: 121 GTGGAKAATLTFMCGGEEGAFAAAKPILEKMGKKIVHCGGAGAGQAAKICNNMILGISMI 180 Query: 181 AVGEAFVLAEKLGLSHQALFDVASTSSGQCWSLTTYCPVPGPVPTSPANNDYKPGFASNL 240 AV EAF L EKLGLSHQALFDVASTSSGQCWSLT+YCPVPGPVP SPANNDYKPGFA+ L Sbjct: 181 AVSEAFALGEKLGLSHQALFDVASTSSGQCWSLTSYCPVPGPVPASPANNDYKPGFATAL 240 Query: 241 MVKDLTLAQDAANAAGAVTPLGKHAQEIYKTFDASGHGGVDFSGIIQHVRALA 293 M+KDLTL+QDAA AAGA TPLG+HAQEIYK F+A+GHGGVDFSGIIQHVR LA Sbjct: 241 MLKDLTLSQDAAKAAGAATPLGQHAQEIYKAFEAAGHGGVDFSGIIQHVRKLA 293